CAPRİPOXVİRUSLARIN HAYVAN SAĞLIĞI ÜZERİNDEKİ ETKİLERİ VE GÜNCEL ANTİVİRAL YAKLAŞIMLAR

Yıl 2024, Cilt: 15 Sayı: 2, 86 - 95, 31.08.2024

Sibel Şurak , Zeynep Akkutay Yoldar

https://doi.org/10.38137/vftd.1457492

Öz

Poxviridae ailesinde yer alan capripoxviruslar, lumpy skin disease (LSD) ve koyun-keçi çiçeği gibi önemli ekonomik kayıplara neden olan hastalıklara yol açar. Salgın kaynaklı kayıpların önüne geçebilmek için aşılama ve karantina gibi klasik profilaksi stratejileri uygulanmaktadır. Profilaksinin yanı sıra farklı yaklaşımlarla terapötik etki yaratabilecek antiviral tedaviler geliştirmek de önemli bir araştırma alanıdır. Antivirallerin yüzyıllardır insan ve hayvan sağlığı için kullanılmasına karşın; teknoloji ve bilimin gelişmesi ile, antiviral tedavilerde yeni ve inovatif yaklaşımlar ortaya çıkmaktadır. Nanoteknoloji, bitki bilimi gibi farklı disiplinlerden yararlanarak, capripoxviruslara karşı etkili antiviral ilaçlar geliştirmek için farklı materyallerin antiviral etkinlikleri denenmiştir ve olumlu sonuçlar alınmıştır. Bu derlemede de capripoxvirusların ülkemiz ve dünyadaki önemi ve bu viruslara karşı denenmiş farklı materyallerin antiviral etkileri derlenmiştir. Capripoxviruslara karşı şu anda dünya çapında onaylı bir antiviral bulunmamasına rağmen, bu alandaki araştırmalar hızla ilerlemektedir. Nanoteknolojinin sunduğu imkanlar ve bitkisel kaynaklı antivirallerin potansiyeli, capripoxviruslara karşı etkili tedaviler geliştirmek için büyük umut vadetmektedir.

Anahtar Kelimeler

Antiviral, capripoxvirus, koyun-keçi çiçeği, lumpy skin disease

EFFECTS OF CAPRIPOXVIRUSES ON ANIMAL HEALTH AND CURRENT ANTIVIRAL APPROACHES

Öz

Capripoxviruses, belonging to the Poxviridae family, cause diseases that cause significant economic losses, such as lumpy skin disease (LSD) and sheep-goat pox. Classical prophylaxis strategies such as vaccination and quarantine are applied to prevent epidemic-related losses. In addition to prophylaxis, developing antiviral treatments that can create therapeutic effects with different approaches is also an important area of research. Although antivirals have been used for human and animal health for centuries; With the development of technology and science, new and innovative approaches are emerging in antiviral treatments. Using different disciplines such as nanotechnology and plant science, the antiviral activities of different materials have been tested to develop effective antiviral agents against capripoxviruses and positive results have been obtained. In this review, the importance of capripoxviruses in our country and the world and the antiviral effects of different materials tested against these viruses are compiled. Although there is currently no globally approved antiviral against capripoxviruses, research in this field is progressing rapidly. The opportunities offered by nanotechnology and the potential of plant-derived antivirals hold great promise for developing effective treatments against capripoxviruses.

Anahtar Kelimeler

Antiviral, capripoxviruses, sheep-goat pox, lumpy skin disease

Kaynakça

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