A rare case of perivulvar hemangiosarcoma in a bitch

Abstract

An 11-year old, Rottweiler bitch was presented to the clinic with the complaint of a huge mass protruding from the left side of the vulvar labium. The bitch had been ovariohysterectomized due to the pyometra 2 years ago. The perivulvar mass was surgically removed by using an electrocautery device under general anesthesia. Macroscopically, the pedunculated mass was 20 cm x 25 cm in diameter, capsulated and slightly firm. Histopathological examination revealed that the mass was a hemangiosarcoma originating from the mucosa. Marked anisocytosis and anisokaryosis were noted in microscopic examination. Immunohistochemically, neoplastic cells showed positive staining for von-Willebrand factor-related antigen. On postoperative 3rd and 12th month follow-up protocols, the female dog was in good health condition and no metastases were detected in any organ. In this report, clinical follow-up, histological and immunohistological examination of a rare perivulvar hemangiosarcoma case in a female dog was presented.

Keywords

• Bitch
• Hemangiosarcoma
• Immunohistochemistry
• Perivulvar

Dişi bir köpekte nadir bir perivulvar hemanjiosarkom olgusu

Öz

Onbir yaşında, Rottweiler ırkı, dişi bir köpek vulvar labiumun sol yanından çıkıntı yapan kitle şikayeti ile kliniğimize getirildi. Köpeğe 2 yıl önce pyometra nedeniyle ovariohisterektomi uygulanmıştı. Genel anestezi altında elektrokoter cihazı kullanılarak perivulvar kitle cerrahi olarak çıkarıldı. Makroskopik olarak 20 cm x 25 cm çapında, kapsüllü ve hafif sert saplı kitle görüldü. Histopatolojik incelemede, kitlenin mukozadan köken alan bir hemanjiyosarkom olduğu saptandı. Mikroskobik incelemede belirgin anizositoz ve anizokaryoz kaydedildi. İmmünohistokimyasal olarak neoplastik hücreler, von-Willebrand faktörü ile ilişkili antijen için pozitif boyanma gösterdi. Operasyon sonrası 3. ve 12. ay takip protokollerinde köpeğin sağlık durumu iyiydi ve herhangi bir organa metastaz göstermedi. Bu olgu sunumunda, dişi bir köpekte nadir görülen bir perivulvar hemanjiyosarkom olgusunun klinik takibi, histolojik ve immünohistolojik bulguları sunulmuştur.

Anahtar Kelimeler

• Hemanjiosarkom
• Immunohistokimya
• Dişi Köpek
• Perivulvar

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