Dirençli bakterilerle komplike köpek kronik yangısal pododermatit: klinik vaka serileri

Öz

Pododermatit, tırnak derisinin, interdigital boşluğun, taban pedlerinin ve tırnak kıvrımlarının yangısı olarak tanımlanır. Pedal foliküliti ve furunküloz olarak bilinen karmaşık durumlar, çok faktörlü yapıları nedeniyle sıklıkla karmaşık tanı ve tedavi gerektirir. Kronik ve ilerleyici pododermatit semptomları gösteren dört köpek, Ondokuzmayıs Üniversitesi Hayvan Hastanesi'ne getirildi. Eksüdatların bakteriyolojik incelemesi, Alman Çoban, Labrador Retriever ve Setter ırkı köpeklerde Metisiline Dirençli Staphylococcus aureus (MRSA) enfeksiyonu ortaya konuldu. MRSA izolatı sırasıyla sadece teikoplanin, gentamisin ve enrofloksasine duyarlı olark bulundu. Melez ırk köpekte, ampisilin/sulbaktama duyarlı Vankomisin Dirençli Enterococcus spp. izole edildi. Antinükleer Antikor Testleri yüksek pozitif titreler ortaya çıkardı. Her bir köpeğe duyarlı antibiyotikler prednizolon tedavisi kombinasyonu ile birlikte kullanılması önemli bir iyileşme sağladı. Sonuç olarak, köpeklerde kronik pododermatit vakalarında antibiyotiğe dirençli bakteriler ve immünomodülatör yanıt veren etiyoloji birlikte değerlendirilmelidir.

Anahtar Kelimeler

• Köpek
• Pododermatit
• Dirençli Bakteri
• İmmunmodülatör

Canine chronic inflammatory pododermatitis complicated with resistant bacteria: clinical case series

Abstract

Pododermatitis is defined as the inflammation of the paw skin of nails, interdigital space, base pads, and nail folds. Complex conditions known as pedal folliculitis and furunculosis often need complicated diagnosis and treatment because of their multifactorial nature. Four dogs with symptoms of chronic and progressive pododermatitis were admitted to the Ondokuzmayis University Animal Hospital. Bacteriological examination of exudates revealed Methicillin Resistant Staphylococcus aureus (MRSA) infection in German Shepherd, Labrador Retriever and Setter dogs. The MRSA isolate was sensitive only to teicoplanin, gentamicin and enrofloxacin, respectively. From the infection of the mixed-breed dog, ampicillin/sulbactam susceptible Vancomycin-Resistant Enterococcus spp. was isolated. Antinuclear Antibody Tests revealed high positive titers. The use of antibiotics sensitive for each dog together with the combination of prednisolone treatment resulted in significant recovery. In conclusion, antibiotic-resistant bacteria and immunomodulatory responsive etiology should be considered together in cases of chronic pododermatitis in dogs.

Keywords

• dog
• pododermatitis
• immunomodulatory
• resistant bacteria

Kaynakça

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