Are cardiac and oxidant-antioxidant status different in female cats in sexual cycle

Yıl 2025, Cilt: 96 Sayı: 1, 23 - 31, 15.01.2025

İshak Gökçek , Ahmet Gözer

https://doi.org/10.33188/vetheder.1527937

Öz

This study aimed to investigate the levels of cardiac troponin I (cTnI), malondialdehyde (MDA), glutathione (GSH), and glutathione peroxidase (GSH-Px) during the sexual cycle in domestic female cats. For this purpose, blood samples were collected from twenty-six cats, with an equal number of animals in each group. The cats were divided into two groups luteal and non-luteal periods based on their progesterone levels. Malondialdehyde was used to assess the oxidant status, while GSH and GSH-Px were used to evaluate the antioxidant status. Cardiac troponin I levels were measured to assess cardiac status. The results revealed no significant differences in cardiac troponin I, MDA, or GSH levels between the groups, while GSH-Px levels showed a statistically significant difference. In conclusion, further research is necessary to explore the molecular mechanisms involved in the sexual cycle of domestic female cats

Anahtar Kelimeler

Domestic cats, cardiac status, oxidant-antioxidant status, sexual cycle

Dişi kedilerde kardiyak ve oksidan-antioksidan durum seksüel siklus dönemlerinde farklı mıdır?

Öz

Bu çalışmada seksüel siklus dönemindeki evcil dişi kedilerde kardiyak troponin I (cTnI), malondialdehid (MDA), glutatyon (GSH) ve glutatyon peroksidaz (GSH- Px) düzeylerinin araştırılması amaçlandı. Bu amaç doğrultusunda her grupta eşit sayıda hayvan olacak şekilde yirmi altı adet kediden kan örnekleri alınarak progesteron seviyelerine göre luteal ve non-luteal dönem olmak üzere iki gruba ayrıldı. Elde edilen kan örneklerinde oksidan durum değerlendirilmesi amacıyla MDA, antioksidan durum için GSH, GSH-Px; kardiyak durum için ise kardiyak troponin I seviyeleri ölçüldü. Elde edilen kan örneklerinde kardiyak troponin I, MDA ve GSH seviyelerinin gruplar arası istatiksel farklılığa neden olmadığı görülürken GSH- Px’in ise iki grup arasında istatiksel anlamda birbirinden farklı olduğu görüldü. Sonuç olarak evcil dişi kedilerde seksüel siklus dönemindeki moleküler mekanizmaların ortaya konması amacıyla daha ileri araştırmaların yapılması gerekliliği görülmektedir.

Anahtar Kelimeler

evcil kediler, kardiyak durum, oksidan-antioksidan durum, seksüel siklus

Kaynakça

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