Measurement of Kidney Dimensions by Ultrasonography and Investigation of the Incidence of Polycystic Kidney Disease in Van Cats

Abstract

This study was conducted to measure kidney size in Van cats using ultrasonography and to investigate the incidence of polycystic kidney disease (PKD). The study's animal material consisted of 80 Van cats of different ages, genders, and eye colors. After performing general clinical examinations on the animals, measurements of the right and left kidneys (kidney length, height, width, volume, cortex length, medulla length, abdominal aorta, and RI) were taken using an ultrasound device. Ultrasound examinations conducted on Van cats of different ages, genders, and eye colors revealed that kidney size varied according to age group, but gender and eye color had no effect on kidney size. In kidney measurements performed on cats of different age groups, it was determined that the measurements in both the right and left kidneys showed statistically significant differences between groups. It was observed that these values generally increased from group 1 to group 4 (Group 1: <6 mounts; Group 2: ≥6-<12 mounts; Group 3: ≥12-<24 mounts; Group 4: ≥24 mounts) and that kidney size varied according to age. The findings were recorded. The right and left kidneys of the cats were examined using ultrasound to investigate whether they had PKD, and no cats were found to have PKD. In conclusion, this study was the first to investigate the determination of normal kidney size and the presence of PKD in Van cats using ultrasonography. None of the cats included in the study had PKD, and there were no differences in kidney size compared to other cat breeds.

Keywords

• Kidney
• Kidney
• kidney measurement
• PKD ultrasonography
• Van cat

Kaynakça

1. 1.Eroğlu T. Türkiye’deki Bazı Kedi Irklarının GenetikYapılarının Mıkrosatellitlerle İncelenmesi. Yüksek LisansTezi. Konya Selçuk Üniversitesi; 2007.
2. 2.Özkan C, Karaca M, Özdal N. Topical selamectin treatmentof otodectes cynotis in Van cats. Türkiye Parazitol Derg.2013;37:269-272.
3. 3.Bilgiç B, Özkan C, Moscati L, et al. Redox balance in Vancats and it’s association with age, gender and eye color. JHellenic Vet Med Soc. 2024;75(2):7301-7308.
4. 4.Karadağ S. Türkiye'nin yerel ırklarından Ankara ve Vankedilerinin ırk özellikleri. Manas J Agric Vet Life Sci.2025;15(1):161-166.
5. 5.Çayır N. Kedilerde Farklı Görüntüleme Yöntemleri ileBöbreklerin Morfolojik İncelenmesi. Yüksek Lisans Tezi.Aydın Adnan Menderes Üniversitesi; 2008.
6. 6.Şındak N, Şelçukbiricik H. Köpeklerin karın içi organhastalıklarının ultrasonografi ile değerlendirilmesi. Van VetJ.2006;17(1-2):75-79.
7. 7.Şirin ÖŞ, Fidan M, Bumin A. Acil veteriner hekimliğindeultrasonografik muayene yöntemleri. Erciyes Üniv Vet FakDerg. 2021;18(1):57-61.
8. 8.Canooğlu E. Kedilerde Meme Bezinin UltrasonografikMuayenesi. Çelik HA, editör. Evcil Hayvanlarda Meme Sağlığıve Hastalıklarında Ultrasonografinin Yeri ve Önemi. Ankara:Türkiye Klinikleri Yayınevi;2024;10(1):40-46.

9. 9. Silva CEF, Foncesa MAFS, Borges GS, Costa DV, Lopes MM,Öliverira LM. Gastrointestinal ultrasound in dogs:scientometric analysis. Adv Res. 2024;25(6):21-28.
10. 10.Şen Y, Turan E. Basic ultrasonography. Türkiye Klinikleri JVet Sci. 2025;11(1):49-53.
11. 11.Debruyn K, Haers H, Combes A, et al. Ultrasonographyof the feline kidney: technique, anatomy and changesassociated with disease. J Feline Med Surg. 2012;14:794-803.
12. 12.Kaymaz AA, Bayrakal A. Üriner Sistem Ultrasonografisi.Bayrakal A, İskefli O, editörler. Kedi ve Köpeklerde TemelUltrasonografi ve Ekokardiyografi. Ankara: Güneş TıpKitapevi; 2021:195-221.
13. 13.Bayrakal A, İskefli O. Böbrekler ve Üreterler. Bayrakal A, Vet Sci Pract. 2026;21(1):1-9. doi: 10.17094/vetsci.1752619 İskefli O, editörler. Uygulamalı Küçük Hayvan Ultrasonografisi. Ankara: Güneş Tıp Kitapevi; 2024:81-90.
14. 14.Turgut K. Veteriner Klinik Laboratuvar Teşhis. 2. Baskı.Ankara, Bahçıvanlar Basım Sanayi AŞ; 2000.
15. 15.Alkan Z. Kedilerde böbreklerin ultrasonografikanatomisi. Kafkas Üniv Vet Fak Derg. 1995;1(1):42-46.
16. 16.Clorkson CE, Flecher TF. Anatomy and physiology.Bartges J, Polzin JD, eds. Nephrology and Urology of SmallAnimals. New Delhi India: Wiley-BlackwellPuplishing;2011:3-10.
17. 17.Debruyn K, Paepa D, Daminet S, et al. Renal dimensionsat ultrasonograpyhy in healthy Ragdoll cats with normalkidney morphology: Correlation with age, gender andbodyweight. J Feline Med Surg. 2013;15(12):1046-1051.
18. 18.Jaturanratsamee K, Choisunirachon N, Soontornvipart K,Darawiroj D, Srisowanna N, Thanaboonnipat C.Ultrasonographic kidney length-to-abdominal aorticdiameter for the diagnosis of feline chronic kidney disease:A preliminary study. Vet World. 2023;16(5):1114-1121.
19. 19.Anjou MA, Penninck D. Kidneys and ureters. Anjou MA,Penninck D, eds. Atlas of Small Animal Ultrasonography.USA: Blackwell Publishing; 2013:331-360.
20. 20.Nivy R, Lyons AL, Aroch I, Segev G. Polycystic kidneydisease in four British shorthair cats with successfultreatment of bacterial cyst infection. J Small anim Pract.2015;56:585-589.
21. 21.Schirrer L, Marin-Garcia JP, Llobat L. Feline polycystickidney disease: An update. Vet Sci. 2021;8:269.
22. 22.Woszuk JN, Sobczak M, Sawicz Z, et al. First report onthe presence of a common pathogenic variant in the PKD1gene, causing polycystic kidney disease, in a series of relatedSphynx cats. Top Compain Anim Med. 2024;63:100928.
23. 23.Saberi N, Khaksar E, Molazem M, Rafiee SM.Cardiovascular changes in Persian cats with polycystickidney disease: a study of cardiac troponin I,echocardiography and blood pressure. J Feline Med Surg.2025;27(1):1-7.
24. 24.Griffin S. Feline abdominal ultrasonography: What’snormal? What’s abnormal? The kidneys and perinephricspace. J Feline Med Surg. 2020;22:409-427.
25. 25.Reichle KJ, Dibartola PS, Leveille R. Renalultrasonographic and computed tomographic appearance,volume, and function of cats with autosomal dominantpolycystic kidney disease. Vet Radiol Ultrasound.2002;43(4):368-373.
26. 26.Lee YJ, Chen HY, Hsu WL, Ou CM, Wong ML. Diagnosis offeline polycystic kidney disease by a combination ofultrasonographic examination and PKD1 gene analysis. VetRec. 2010;167:614-617.
27. 27.Gabow PA. Autosomal dominant polycystic kidneydisease: More than a renal disease. Am J Kidney Dis.1990;16(5):403-413.
28. 28.Beck C, Lavelle RB. Feline polycystic kidney disease inPersian and other cats: A prospective study usingultrasonography. Aust Vet J. 2001;79(3):181-184.
29. 29.Tümer K, İssi M. Chronic renal failure associated withpolycystic kidney disease in a Persian cat. F Ü Sağ Bil VetDerg. 2017;31(3):265-267.
30. 30.Bonazzi M, Volta A, Gnudi G, et al. Comparison betweenultrasound and genetic testing for the early diagnosis ofpolycystic kidney disease in Persian and Exotic Shorthaircats. J Feline Med Surg. 2009;11:430-434.
31. 31.Lyons AL, Biller SD, Erdman AC, et al. Feline polycystickidney disease mutation identified in PKD1. J Am SocNephrol. 2004;15(10):2548-2555.
32. 32.Lulich JP, Osbone CA. Polycystic kidney disease. Tillet LP,Smith WKF, eds. Blackwells Five-Minute Veterinary Consult:Canine and Feline. New Delhi India: Wiley-BlackwellPublished; 2011:1121.
33. 33.Tipisca V, Murino C, Cortese L, et al. Resistive index forkidney evaluation in normal and diseased cats. J Feline MedSurg. 2016;18(6):471-475.
34. 34.Widmer RW, Mattoon JS, Vaden SL. Urinary tract.Mattoon JS, Sellon RK, Berry CR, eds. Small AnimalDiagnostic Ultrasound. Chine: Elsevier; 2020:583-630.
35. 35.Canpolat İ. Renal ultrasonographic anatomy in dogs andcats. Turk J Vet Anim Sci. 1996;20(6):419-423.
36. 36.Park I, Lee H, Kim J, et al. Ultrasonographic evaluation ofrenal dimension and resistive index in clinically healthyKorean domestic short-hair cats. J Vet Sci. 2009;9:415-419.
37. 37.Novellas R, Ruiz De Gopegui R, Espada Y. Assessment ofrenal vascular resistance and blood pressure in dogs andcats with renal disease. Vet Rec. 2010;166:618-623.
38. 38.Temiz S. Kedilerde Hernia Diafragmatikanın BöbrekResiztif ve Pulzatif İndeks Değerlerine Etkisi. Yüksek LisansTezi. Ankara Üniversitesi; 2017.
39. 39.Ostrowska J, Kielbowiez Z, Dorobisz ZU, Atamaniuk W,Fulbiszewska PA, Kinda W. Resistive index (RI) obtained inrenal interlobar arteries of normal dog and cat by means ofdoppler ultasonograpy. Pak Vet J. 2016;36(01):45-48.
40. 40.River JB, Walter AP, Polzin JD, King LV. Duplex dopplerestimation of intrarenal pourcelot resistive index in dog andcat with renal disease. JVIM. 1997;11(4):250-260.
41. 41.Gönül R, Koenhemsi L, Oralkan D, Or ME, Uysal A. Kronikböbrek yetmezliği bulunan bir kedide renal vaskuler direncindoppler ultrasonografi ile saptanması. Van Vet J.2011;22(2):111-113.
42. 42.Barthez P, Riviver P, Begon D. Prevalence of polycystickidney disease in Persian and Persian related cats in France.J Feline Med Surg. 2003;5:345-347.
43. 43.Cannon JM, Mackay AD, Barr FJ, Rudorfh H, Bradley KJHones TJG. Prevalence of polycystic kidney disease inPersian cats in the United Kingdom.