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Development of a Cost-Effective Novel CNN Model for Breast Cancer Classification in Histopathological Images

Cilt: 29 Sayı: 3 31 Aralık 2024
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Development of a Cost-Effective Novel CNN Model for Breast Cancer Classification in Histopathological Images

Öz

Cancer, is a leading cause of disease and death worldwide, affecting both advanced industrialized and developing nations. Breast cancer, specifically among women, is a highly prevalent and serious type of cancer, making it a focal point for extensive research in the field of medicine. In the diagnosis of breast cancer, histopathological images play a crucial role because of the abundance of valuable phenotypic information they contain. To enhance the accuracy and objectivity of breast histopathological image analysis (BHIA), classification, and detection tasks are performed on these images using deep learning architecture approaches. In a preliminary experiment conducted in this paper using the Breast Cancer Histopathological Database (BreakHis), four state-of-the-art and custom CNN architectures were proposed. The experimental results demonstrate the notable performance of the proposed custom model at 40x and 200x magnification factors, reaching accuracies of 97.49% and 97.77%, surpassing other models. The ResNet-50 model achieved higher accuracy at 100x and 400x magnifications, with accuracies of 98.56% and 96.43%, respectively. Compared to other state-of-the-art models, the proposed CNN model not only shows efficient training with a significantly shorter timeframe but also features a reduced number of layers, highlighting its superior computational efficiency. Although the parameter count is higher than that of one of the models, the model strikes a favorable balance between computational efficiency and model capacity. In light of the achieved outcomes and the existing literature, forthcoming studies endeavor can be pursued further to enhance the performance values in breast cancer classification.

Anahtar Kelimeler

Breast cancer, Classification, CNN, Deep learning, Histopathology Images

Kaynakça

  1. Addo, D., Zhou, S., Sarpong, K., Nartey, O. T., Abdullah, M. A., Ukwuoma, C. C., & Al-antari, M. A. (2024). A hybrid lightweight breast cancer classification framework using the histopathological images. Biocybernetics and Biomedical Engineering, 44(1), 31-54. https://doi.org/10.1016/j.bbe.2023.12.003
  2. Ali, M. S., Miah, M. S., Haque, J., Rahman, M. M., & Islam, M. K. (2021). An enhanced technique of skin cancer classification using deep convolutional neural network with transfer learning models. Machine Learning with Applications, 5, 100036. https://doi.org/10.1016/j.mlwa.2021.100036
  3. Alom, M. Z., Yakopcic, C., Nasrin, M. S., Taha, T. M., & Asari, V. K. (2019). Breast cancer classification from histopathological images with inception recurrent residual convolutional neural network. Journal of Digital Imaging, 32, 605-617. https://doi.org/10.1007/s10278-019-00182-7
  4. Arnold, M., Morgan, E., Rumgay, H., Mafra, A., Singh, D., Laversanne, M., Vignat, J., Gralow, J. R., Cardoso, F., & Siesling, S. (2022). Current and future burden of breast cancer: Global statistics for 2020 and 2040. The Breast, 66, 15-23. https://doi.org/10.1016/j.breast.2022.08.010
  5. Boumaraf, S., Liu, X., Wan, Y., Zheng, Z., Ferkous, C., Ma, X., Li, Z., & Bardou, D. (2021a). Conventional machine learning versus deep learning for magnification dependent histopathological breast cancer image classification: A comparative study with visual explanation. Diagnostics, 11(3), 528. https://doi.org/10.3390/diagnostics11030528
  6. Boumaraf, S., Liu, X., Zheng, Z., Ma, X., & Ferkous, C. (2021b). A new transfer learning based approach to magnification dependent and independent classification of breast cancer in histopathological images. Biomedical Signal Processing and Control, 63, 102192. https://doi.org/10.1016/j.bspc.2020.102192
  7. Brown, J. S., Amend, S. R., Austin, R. H., Gatenby, R. A., Hammarlund, E. U., & Pienta, K. J. (2023). Updating the definition of cancer. Molecular Cancer Research, 21(11), 1142-1147. https://doi.org/10.1158/1541-7786.MCR-23-0411
  8. Budak, Ü., & Güzel, A. (2020). Automatic grading system for diagnosis of breast cancer exploiting co-occurrence shearlet transform and histogram features. IRBM, 41(2), 106-114. https://doi.org/10.1016/j.irbm.2020.02.001.
  9. Burçak, K. C., Baykan, Ö. K., & Uğuz, H. (2021). A new deep convolutional neural network model for classifying breast cancer histopathological images and the hyperparameter optimisation of the proposed model. The Journal of Supercomputing, 77(1), 973-989. https://doi.org/10.1007/s11227-020-03321-y
  10. Chattopadhyay, S., Dey, A., Singh, P. K., Oliva, D., Cuevas, E., & Sarkar, R. (2022a). MTRRE-Net: A deep learning model for detection of breast cancer from histopathological images. Computers in Biology and Medicine, 150, 106155. https://doi.org/10.1016/j.compbiomed.2022.106155

Kaynak Göster

APA
Jaf, K. N. N., & İnik, Ö. (2024). Development of a Cost-Effective Novel CNN Model for Breast Cancer Classification in Histopathological Images. Yüzüncü Yıl Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 29(3), 896-912. https://doi.org/10.53433/yyufbed.1498736
AMA
1.Jaf KNN, İnik Ö. Development of a Cost-Effective Novel CNN Model for Breast Cancer Classification in Histopathological Images. YYUFBED. 2024;29(3):896-912. doi:10.53433/yyufbed.1498736
Chicago
Jaf, Karwan Noori Nadr, ve Özkan İnik. 2024. “Development of a Cost-Effective Novel CNN Model for Breast Cancer Classification in Histopathological Images”. Yüzüncü Yıl Üniversitesi Fen Bilimleri Enstitüsü Dergisi 29 (3): 896-912. https://doi.org/10.53433/yyufbed.1498736.
EndNote
Jaf KNN, İnik Ö (01 Aralık 2024) Development of a Cost-Effective Novel CNN Model for Breast Cancer Classification in Histopathological Images. Yüzüncü Yıl Üniversitesi Fen Bilimleri Enstitüsü Dergisi 29 3 896–912.
IEEE
[1]K. N. N. Jaf ve Ö. İnik, “Development of a Cost-Effective Novel CNN Model for Breast Cancer Classification in Histopathological Images”, YYUFBED, c. 29, sy 3, ss. 896–912, Ara. 2024, doi: 10.53433/yyufbed.1498736.
ISNAD
Jaf, Karwan Noori Nadr - İnik, Özkan. “Development of a Cost-Effective Novel CNN Model for Breast Cancer Classification in Histopathological Images”. Yüzüncü Yıl Üniversitesi Fen Bilimleri Enstitüsü Dergisi 29/3 (01 Aralık 2024): 896-912. https://doi.org/10.53433/yyufbed.1498736.
JAMA
1.Jaf KNN, İnik Ö. Development of a Cost-Effective Novel CNN Model for Breast Cancer Classification in Histopathological Images. YYUFBED. 2024;29:896–912.
MLA
Jaf, Karwan Noori Nadr, ve Özkan İnik. “Development of a Cost-Effective Novel CNN Model for Breast Cancer Classification in Histopathological Images”. Yüzüncü Yıl Üniversitesi Fen Bilimleri Enstitüsü Dergisi, c. 29, sy 3, Aralık 2024, ss. 896-12, doi:10.53433/yyufbed.1498736.
Vancouver
1.Karwan Noori Nadr Jaf, Özkan İnik. Development of a Cost-Effective Novel CNN Model for Breast Cancer Classification in Histopathological Images. YYUFBED. 01 Aralık 2024;29(3):896-912. doi:10.53433/yyufbed.1498736