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Öz

Aim: Leiomyosarcoma is a rare malign neoplasm of the uterus. The current retrospective study examined leiomyosarcoma who were evaluated at our institution over a 8 year period.Material-Method: Clinical records of the cases operated with the diagnosis of leiomyosarcoma, between January 2005 and October 2013, reviewed retrospectively. All material belonging to 22 cases were evaluated histologically.Results: There were 22 females, whose age range from 41 to 73 (median 54 years). The neoplasm measured from 1,5 to 16 cm greatest diameter ( median 8,8 cm).Conclusion: In conclusion, leiomyosarcoma is a aggressive neoplasm. The diagnosis of leiomyosarcomas depends on a combination of microscopic features. Our cases clinicopathological correlation values were parallel to the literature.

Anahtar Kelimeler

• Leiomyosarcoma, uterus, immunohistochemistry, anaplasia, mitoticindexCiLT: 45 YIL : 2014 SAYI: 2ZEYNEP KAMİL TIP BÜLTENİ 2014;45:65-70KLiNiK ARAŞTIRMA

Uteri̇n Lei̇omyosarkom: 22 Olguda Patolojik Değerlendirme (Uterine Leiomyosarcoma: Pathologic evaluation of 22 Cases)

Öz

Amaç: Leiomyosarkom uterusun nadir görülen malign bir tümörüdür. Bu retrospektif çalışmada 8 yıllık periotta bölümümüzde değerlendirilmiş leiomyosarkom tanısı almış olgular çalışılmıştır.

Materyal-Metod: Ocak 2005 ile  Ekim 2013 tarihleri arasında leiomyosarkom tanısı ile opere edilen olguların tüm hastane kayıtları geriye yönelik olarak değerlendirildi. 22 hastaya ait tüm materyeller histolojik olarak değerlendirildi.

Bulgular: Yaşları 41 ile 73 arasında değişen (ortalama 54) 22 kadın hasta değerlendirildi. Tümörlerin en geniş çapları 1,5 ile 16 cm arasında değişiyordu (ortalama 8,8).

Sonuç: Leiomyosarkom agresif bir neoplazmdır. Leiomyosarkomların tanısı kombine mikroskopik bulgulara dayanmaktadır. Bizim olgularımızın klinikopatolojik verileri literatür verilerine paralellik göstermekteydi.

Anahtar Kelimeler: leiomyosarkom, uterus, immunohistokimya, anaplazi, mitotik endeks.

Abstract

Aim: Leiomyosarcoma is a rare malign neoplasm of the uterus. The current retrospective study examined leiomyosarcoma who were evaluated at our institution over a  8 year period.

Material-Method: Clinical records of the cases operated with the diagnosis of leiomyosarcoma, between January 2005 and October 2013, reviewed retrospectively. All material belonging to 22 cases were evaluated histologically.

Results: There were  22 females, whose age range from 41 to 73 (median 54 years). The neoplasm measured from 1,5 to 16 cm greatest diamater ( median 8,8 cm).

Conclusion: In conclusion, leiomyosarcoma is a aggressive neoplasm. The diagnosis of leiomyosarcomas depends on a combination of microscopic features. Our  cases  clinicopathological correlation values were parallel to the literature.

Keywords: Leiomyosarcoma, uterus, immunohistochemistry,  anaplasia, mitotic index

Anahtar Kelimeler

• leiomyosarkom, uterus, immunohistokimya,anaplazi,mitotik endeks.

Kaynakça

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