Prognostik significance of deep adenomyotic foci involvement with minimal invasion of surrounding myometrium in endometrial carcinoma

Abstract

Objective: To investigate prognostic significance ofdeep adenomyotic foci involvement with minimal invasion of surrounding myometrium in endometrial carcinoma Material and Method: Six cases of endometrial adenocarcinoma involving adenomyosis as defined above were followed-up between 7 and 27 months(mean 17 months). All cases were InternationalFederation of Gynecology and Obstetrics (FIGO) grade I and FIGO stage I. Resuts: After 7-27 months follow-up, ali cases were alive with no evidence of recurrent disease. Conlusion: Because of the small number of cases in this study and the short duration of follow up, we couldn't get any statistical support. Eventhough, deep adenomyotic foci involvement with minimal invasion of surrounding myometrium in endometrial carcinoma don't seem to behave like ordinary myoinvasion at same level. it is necessary further investigations with large number of cases and long follow-up periods on this subject which has not been completely enlightened yet.

Keywords

• Endometriosis,Endometrial Neoplasms,Genital Neoplasms, Female

Derin adenomyozis odaklarında endometrial karsinom tutulumu ve bu odaklara komşu minimal myoinvazyonun prognostik önemi

Öz

Amaç: Derin adenomyozis odaklarında, yüzey endometriumdan kaynaklanan endometrial karsinom tutulumu ve bu odaklara komşu minimal myoinvazyonun prognostik önemini araştırmak. Materyal ve Metod : Yukarıdaki tanıma, uyan, uluslararası jinekoloji ve obstetrik federasyonu (FIGO) grade I ve FIGO evre I olan altı adet endometrial karsinomlu olgu 7-27 (ortalama 17)' ay arasında değişen süreyle izlendi. Bulgular 7-27 ay arasında değişen süreyle izlem sonucunda, altı olgunun hiçbirinde nüks ya da ölüm saptanmadı. Sonuçlar. Olgu sayısının azlığı ve takip süresinin kısalığı nedeniyle istatiksel olarak desteklenmiş bir sonuca ulaşamamakla birlikte, bulgularımız; endometrial karsinom tarafından tutulmuş derin adenomyozis odaklan ve buna komşu minimal myoınvazyonun,derin gerçek myoinvazyon gibi davranmadığını düşündürmektedir. Henüz aydınlanmamış olan bu konuda geniş ve uzun takipli çalışmalara ihtiyaç vardır.

Anahtar Kelimeler

• Endometriyoz,Endometriyum neoplazmları,Genital neoplazmlar, dişi

Kaynakça

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