Histologic chorioamnionitis and preterm delivery

Öz

Objective: To determine the effects of histological chorioamnionitis in preterm delivery and to investigate the other causes. Material and Methods: The study group consisted of 65 preterm and 71 term pregnancies who are singleton, in active labor and without rupture of membranes. The patients were questioned about their obstetric history, and blood, urine sample for laboratory analysis and vaginal culture were obtained. All placentas were evaluated histopathologically and searched for histological chorioamnionitis. Results: In 2 (3.1%) of 65 preterm labors and 1 (%1.4) of 71 term labors, histological chorioamnionitis was detected. In terms of histological chorioamnionitis, there was no statistical difference between the groups (p>0.05). Also, in terms of history of previous cesarean section, gestational diabetes mellitus and history of urinary tract infection, statistically significant difference were present between preterm and term groups (p=0.007, 0.043, 0.04). Conclusion: The result of our study does not show the relationship between histological chorioamnionitis and preterm delivery. It might be due to the small size of our sample group. Therefore, a better understanding of the presence of histological chorioamnionitis on preterm delivery, there is requirement of longdated several studies.

Anahtar Kelimeler

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Histolojik koioamnionitin erken doğum üzerindeki etkisi

Öz

Amaç: Histolojik korioamniorıitin erken doğum üzerindeki etkisini ve erken doğumu etkileyen diğer faktörleri araştırmak amaçlanmıştır.. Yöntem: Çalışmada aktif eylemde olan , erken membrane rupture olmayan ve tekil gebelikleri içeren 65 preterm ve 71 term gebelerden alınan plasentalar histopatolojik olarak incelenmiştir. Bunun yanında tüm hastalardan obstetric anamnez, kan, idrar ve vajinal kültür örnekleri alınarak olası etiyolojik faktörler araştırılmıştır. Bulgular: Plasentaların histopatolojik olarak incelenmesi sonrası preterm doğumlar içerisinde 2 (3.1%), term doğumlar içerisinde 1 (%1.4) oranında histolojik korioamnit saptanmıştır. Geçirilmiş sezaryen doğum öyküsü, bu gebeliğinde saptanan gestasyonel diyabet ve idrar yolu enfeksiyonu hikayesi pretem doğum yapan gebelerde istatiksel anlamlı olarak daha yüksek bulunmuştur. Sonuç: Bu çalışmanın sonucunda histolojik koryoamniyonit ve preterm doğum ilişkisi koryoamniyonit vakalarının sayıca yetersiz olmasından dolayı söylenemez.Bu nedenle bu konuda daha fazla sayıda ve uzun süreli çalışmalara ihtiyaç vardır.

Anahtar Kelimeler

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Kaynakça

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