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Factors associated with success of induction of labor with dinoprostone vaginal system and outcomes

Yıl 2016, , 6 - 10, 06.03.2016
https://doi.org/10.16948/zktb.08796

Öz

Objective: The aim of this study was to evaluate factors associated with success of induction of labor with dinoprostone vaginal system and assess maternal and fetal outcomes.

Material and Method: One hundred and three patients were evaluated retrospectively. Primary outcomes were considered proportion of women achieving vaginal delivery within 24 hours. Secondary outcome measures were assessed as tachysystole, hyper stimulation, oxytocin requirement, cesarean section rate, fetal distress, meconium stained liquor, postpartum hemorrhage, cervical-vaginal tears, fetal death and vaginal birth achieved post hours, and side effects such as hyperprexia, vomiting, and diarrhea. The factors associated with success of dinoprostone use were evaluated comparing between vaginal birth and cesarean section groups, and fetal outcomes were also assessed.

Results: The success rate of vaginal birth within 24 hours after induction was 28.1%. Age, parity and cervical opening were associated factors with success of achieving vaginal birth within 24 hours (p<0.01). There were no differences between two groups in terms of maternal and fetal outcomes (p>0.05). Apgar scores also were not different between two groups. The maternal and fetal complications which might be attributed to dinoprostone use were rare.

Conclusion: Age, parity and cervical opening were associated factors with success of induction of labor with dinoprostone with rare maternal and fetal complications. 

Kaynakça

  • Madaan M, Agrawal S, Puri M, Nigam A, Kaur H, Trivedi SS. Is low dose vaginal misoprostol better than dinoprostone gel for induction of labor: a randomized controlled trial. J Clin Diagn Res 2014;8(9):OC31-4.
  • WHO recommendations for Induction of labor. World Health Organization 2011. Available from: whqlibdoc.who.int/publications/2011/9789241501156_eng.pdf.
  • Calder AA, Mackenzie IZ. Review of Propess- a controlled release dinoprostone (prostaglandin E2 ) pessary. J Obstet Gynaecol 1997;17 Suppl 2:S53-67.
  • Mukhopadhyay M, Lim KJ, Fairlie FM. Is propess a better method of induction of labour in nulliparous women. J Obstet Gynaecol 2002;22(3):294-5.
  • MacKenzie IZ. Induction of cervical ripening: Evaluation of the prostaglandin E2 release from ‘Propess’ and clinical efficacy and safety in the induction of labour in women with unfavorable and partially favourable cervix. In: Calder AA, Keirse MJNC, MacKenzie IZ, editors. Propess-RS, A Clinical Review. Haslemere, Euromed; 1995, pp 11-15.
  • Westgate J, Williams JA. Evaluation of`Propess-RS: Evaluation of the efficacy, safety and convenience of `Propess-RS’ in the induction of labour. In: Calder AA, Keirse MJNC, MacKenzie IZ, editors. Propess-RS, A Clinical Review. Haslemere, Euromed; 1995, pp 29-35.
  • Browning JJ, Bidgood KA, Calder AA, et al. Propess PMS study: post-marketing surveillance study of the efficacy and safety of ‘Propess’ when administered for the induction of labour at 16 UK centres. Data on: Ferring Pharmaceutical s Ltd., U.K. (1995).
  • Mowat KJ, Carty MJ, and Chat® eld W. R. (1995 ) Propess-RS PMS study. Post-marketing surveillance study of the efficacy, acceptability and safety of `Propess-RS’ at three UK centres . Data on File: Ferring Pharmaceutical s Ltd., U.K.
  • Riboni F, Garofalo G, Pascdi I, Vitulo A, Dell’avanzo W, Battogliarin G, Paternorter D. Labor induction at term: Clinical, biophysical and molecularpredictive factors. Arch Gynrcol Obstet. 2012;28(5):1123-9
  • Crare JM. factors predicting labor inductions success: a critical analysis. Clin Obstet Gynecol. 2006;49(3):573-84.

Vajinal dinoproston sistemi ile yapılan dogum indüksiyonunda başarıyı etkileyen faktörler ve sonuçları

Yıl 2016, , 6 - 10, 06.03.2016
https://doi.org/10.16948/zktb.08796

Öz

Amaç: Bu çalışma dinoproston vajinal sistem ile yapılan doğum indüksiyonunda, başarıyı etkileyen faktörleri, maternal ve fetal sonuçları araştırmayı hedeflemektedir.

Gereç ve Yöntem: Bu retrospektif çalışmada 103 hastanın sonuçları incelendi. Primer sonuç; dinoproston indüksiyonu yapılmış hastaların 24 saat içinde vajinal doğum oranları olarak kabul edildi. Sekonder sonuçlar ise taşisistoli, hiperstimülasyon, oksitosin gerekliliği,  sezeryan gerekliliği, fetal distress, mekonyumla boyalı amnion mayisi, diğer yan etkiler hiperprexi, kusma, ishal, postpartum kanama, cervikal ve vaginal yırtık ile 24 saatten sonraki vajinal doğum olarak değerlendirildi. Dinoproston indüksiyonu sonrası 24 saat içerisinde vajinal doğum başarısı ile ilişkili faktörler ile fetal ve maternal sonuçlar değerlendirildi.

Bulgular: Dinoproston sonrası 24 saat içerisinde vaginal doğum başarısı % 64.1 olarak bulundu. Yaş, parite ve servikal açıklık başarı ile ilişkil faktörler idi (p<0.01). Sezeryana alınan grup ile vajinal doğum yapan grup arasında maternal ve fetal yan etkiler ile komplikasyonlar arasında fark görülmedi (p>0.05). Apgar skorları benzerdi, maternel ve fetal komplikasyonlar nadirdir.

Sonuç: Yaş, parite ve servikal açıklık dinoprostonla yapılan doğum indüksiyonu başarısını etkileyen faktörlerdir. Maternal ve fetal komplikasyonlar ise nadir olarak görülmektedir. 

Kaynakça

  • Madaan M, Agrawal S, Puri M, Nigam A, Kaur H, Trivedi SS. Is low dose vaginal misoprostol better than dinoprostone gel for induction of labor: a randomized controlled trial. J Clin Diagn Res 2014;8(9):OC31-4.
  • WHO recommendations for Induction of labor. World Health Organization 2011. Available from: whqlibdoc.who.int/publications/2011/9789241501156_eng.pdf.
  • Calder AA, Mackenzie IZ. Review of Propess- a controlled release dinoprostone (prostaglandin E2 ) pessary. J Obstet Gynaecol 1997;17 Suppl 2:S53-67.
  • Mukhopadhyay M, Lim KJ, Fairlie FM. Is propess a better method of induction of labour in nulliparous women. J Obstet Gynaecol 2002;22(3):294-5.
  • MacKenzie IZ. Induction of cervical ripening: Evaluation of the prostaglandin E2 release from ‘Propess’ and clinical efficacy and safety in the induction of labour in women with unfavorable and partially favourable cervix. In: Calder AA, Keirse MJNC, MacKenzie IZ, editors. Propess-RS, A Clinical Review. Haslemere, Euromed; 1995, pp 11-15.
  • Westgate J, Williams JA. Evaluation of`Propess-RS: Evaluation of the efficacy, safety and convenience of `Propess-RS’ in the induction of labour. In: Calder AA, Keirse MJNC, MacKenzie IZ, editors. Propess-RS, A Clinical Review. Haslemere, Euromed; 1995, pp 29-35.
  • Browning JJ, Bidgood KA, Calder AA, et al. Propess PMS study: post-marketing surveillance study of the efficacy and safety of ‘Propess’ when administered for the induction of labour at 16 UK centres. Data on: Ferring Pharmaceutical s Ltd., U.K. (1995).
  • Mowat KJ, Carty MJ, and Chat® eld W. R. (1995 ) Propess-RS PMS study. Post-marketing surveillance study of the efficacy, acceptability and safety of `Propess-RS’ at three UK centres . Data on File: Ferring Pharmaceutical s Ltd., U.K.
  • Riboni F, Garofalo G, Pascdi I, Vitulo A, Dell’avanzo W, Battogliarin G, Paternorter D. Labor induction at term: Clinical, biophysical and molecularpredictive factors. Arch Gynrcol Obstet. 2012;28(5):1123-9
  • Crare JM. factors predicting labor inductions success: a critical analysis. Clin Obstet Gynecol. 2006;49(3):573-84.
Toplam 10 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm KADIN HASTALIKLARI VE DOĞUM
Yazarlar

Mehmet Şentürk

Mehmet Budak Bu kişi benim

Yusuf Çakmak

Halit Ataç Bu kişi benim

Mesut Polat

Yayımlanma Tarihi 6 Mart 2016
Yayımlandığı Sayı Yıl 2016

Kaynak Göster

APA Şentürk, M., Budak, M., Çakmak, Y., Ataç, H., vd. (2016). Factors associated with success of induction of labor with dinoprostone vaginal system and outcomes. Zeynep Kamil Tıp Bülteni, 47(1), 6-10. https://doi.org/10.16948/zktb.08796
AMA Şentürk M, Budak M, Çakmak Y, Ataç H, Polat M. Factors associated with success of induction of labor with dinoprostone vaginal system and outcomes. Zeynep Kamil Tıp Bülteni. Mart 2016;47(1):6-10. doi:10.16948/zktb.08796
Chicago Şentürk, Mehmet, Mehmet Budak, Yusuf Çakmak, Halit Ataç, ve Mesut Polat. “Factors Associated With Success of Induction of Labor With Dinoprostone Vaginal System and Outcomes”. Zeynep Kamil Tıp Bülteni 47, sy. 1 (Mart 2016): 6-10. https://doi.org/10.16948/zktb.08796.
EndNote Şentürk M, Budak M, Çakmak Y, Ataç H, Polat M (01 Mart 2016) Factors associated with success of induction of labor with dinoprostone vaginal system and outcomes. Zeynep Kamil Tıp Bülteni 47 1 6–10.
IEEE M. Şentürk, M. Budak, Y. Çakmak, H. Ataç, ve M. Polat, “Factors associated with success of induction of labor with dinoprostone vaginal system and outcomes”, Zeynep Kamil Tıp Bülteni, c. 47, sy. 1, ss. 6–10, 2016, doi: 10.16948/zktb.08796.
ISNAD Şentürk, Mehmet vd. “Factors Associated With Success of Induction of Labor With Dinoprostone Vaginal System and Outcomes”. Zeynep Kamil Tıp Bülteni 47/1 (Mart 2016), 6-10. https://doi.org/10.16948/zktb.08796.
JAMA Şentürk M, Budak M, Çakmak Y, Ataç H, Polat M. Factors associated with success of induction of labor with dinoprostone vaginal system and outcomes. Zeynep Kamil Tıp Bülteni. 2016;47:6–10.
MLA Şentürk, Mehmet vd. “Factors Associated With Success of Induction of Labor With Dinoprostone Vaginal System and Outcomes”. Zeynep Kamil Tıp Bülteni, c. 47, sy. 1, 2016, ss. 6-10, doi:10.16948/zktb.08796.
Vancouver Şentürk M, Budak M, Çakmak Y, Ataç H, Polat M. Factors associated with success of induction of labor with dinoprostone vaginal system and outcomes. Zeynep Kamil Tıp Bülteni. 2016;47(1):6-10.