Determination of Optimum Transfer Day According to Mother's Age in Frozen-Thawed Embryo Cycles

Abstract

Aim: In this study, it was aimed to investigate the effect of transfer day according to maternal age in frozen embryo transfer cycles to determine which age group and which embryo transfer day is optimum.

Material and Method: 205 couples were retrospectively analyzed and included in the study. Patients were divided into 3 groups according to the maternal age. The first group consisted of 63 patients under 30 years old, the second group consisted of 109 patients between 30 - 37 years old, and third group consisted of 33 patients higher than 37 years of age. Patients in each group were separated according to the day of embryo transfer whether on the 3rd or 5th day and pregnancy rates were determined.

Results: Although there were no statistically significant difference between pregnancy rates in the first and second groups (38.7%, 31.2% and 31.6%, 30.6 % respectively), the success rate of the 3rd day transfer in group 3 was about 2.5 times higher than in the fifth day ET group (28% - 12.5% respectively).

Conclusion: It was observed that in the patients under the age of 30 and between the ages of 30-37, the day of transfer did not affect the outcome but in the advanced age group of 37 years embryo transfers on the third day gave better pregnancy results.

Keywords

• Frozen-Thawed Embryo Transfer
• Embryo Development
• ICSI
• Blastocyst

Dondurulmuş- Çözülmüş Embriyo Sikluslarında Anne Yaşına Göre Optimum Transfer Gününün Belirlenmesi

Öz

Amaç: Bu çalışmamızda, dondurma çözme sikluslarında anne yaşına göre transfer gününün etkisini inceleyerek hangi yaş grubunda hangi embriyo transfer gününün daha etkili olduğunun araştırılması amaçlanmıştır.

Materyal ve Method: 205 çift retrospektif olarak incelenerek çalışmaya alınmıştır.  Hastalar anne yaşına göre 3 gruba bölünmüştür. Birinci grup 30 yaş altı 63 hastadan, 2. grup 30-37 yaşa arası 109 hastadan ve 3. grup 37 yaşından büyük 33 hastadan oluşmuştur. Her bir gruptaki hastalar embriyo transferlerinin 3. ya da 5. günde yapılmış olmasına bağlı olarak ayrılmış ve gebelik oranları belirlenmiştir.

Bulgular: 1. ve 2. gruplarda gebelik oranları arasında istatistiksel olarak anlamlı bir fark belirlenmemesine karşılık (%38.7, %31.2 ve %31.6, %30.6 sırasıyla) 3. grupta 3. gün transferindeki başarı oranının 5. güne göre yaklaşık 2.5 kat daha fazla olduğu (%28 - %12.5 sırasıyla) belirlenmiştir.

Sonuç: 30 yaş altı ve 30-37 yaş arası hastalarda transfer gününün sonuçları etkilemediği ancak 37 yaşından büyük ileri yaş grubunda 3. gün embriyo transferlerinin daha iyi gebelik sonucu verdiği gözlemlenmiştir.

Anahtar Kelimeler

• Dondurma Çözme Embriyo Transferi
• Embriyo Gelişimi
• ICSI
• Blastosist

Kaynakça

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