EARLY ONSET HELLP SYNDROME WITH SYSTEMİC LUPUS ERYTEMATOSUS AND ACUTE CHOLECYSTİTİS ATTACK AT 17TH WEEK OF GESTATİON

Yıl 2020, , 46 - 48, 15.01.2020

Gamze Nur Cimilli Şenocak

https://doi.org/10.16948/zktipb.492975

Öz

Hellp syndrome is an atypic, severe and life threatening form of
preeclapmsia, which is usually associated with hemolysis, elevated liver
enzymes and low platelet count. Also it is very important because it causes significantly
maternal and perinatal mortality. It is known that hellp syndrome almost always
occurs after 20 weeks of gestation. But in the presence of some accompanying
diseases, hellp syndrome or severe preeclampsia can occur at earlier
gestational weeks. This may also lead to diagnostic difficulties. In this case,
we described the diagnosis and recovery period of a systemic lupus erytematosus
(SLE) patient who developed hellp syndrome at 17 weeks of gestation. Our experience takes attention that detection
of hellp syndome accompanying diseases like systemic lupus erytematosus
or acute cholecystitis can be difficult and it can occur distinctly at earlier
weeks of gestation. Also the differential diagnosis is very important in such
cases, because many diseases can mimic hellp syndrome.

Anahtar Kelimeler

hellp syndrome, systemic lupus erytematosus, early onset, liver enzymes

17. gebelik haftasında akut kolesistit atağı ve sistemik lupus eritematozus ile birlikte görülen erken başlangıçlı hellp sendromu

Öz

Hellp sendromu, preeklampsinin atipik, şiddetli ve hayatı tehdit eden
bir formu olup genellikle hemoliz, yüksek karaciğer enzimleri ve düşük platelet
düzeyleri ile ilişkilidir. Ayrıca, belirgin maternal ve perinatal mortaliteye
de neden olduğundan önemi büyüktür. Hellp sendromunun hemen her zaman gebeliğin
20. haftadan önce meydana geldiği bilinmektedir. Fakat bazı eşlik eden
hastalıkların varlığında hellp sendromu veya şiddetli preeklampsi daha erken
gebelik haftalarında da görülebilir. Bu durum aynı zamanda tanısal zorluğa da
neden olur. Biz bu olguda, 17. Gebelik haftasında hellp sendromu gelişen bir
sistemik lupus eritematozus (SLE) hastasının tanı ve tedavi periodunu anlattık.
Çalışmamız; hellp sendromunun SLE ya da akut kolesistit gibi eşlik eden hastalıklar
varlığında tespit edilmesinin zorluğuna ve şaşırtıcı olarak erken gebelik
haftalarında meydana gelebilmesine dikkat çekmektedir. Aynı zamanda, böyle
olgularda, birçok hastalık hellp sendromunu taklit edebileceğinden ayırıcı tanı
da çok önemlidir.

Anahtar Kelimeler

hellp sendromu, sistemik lupus eritematozus, erken başlangıç, karaciğer enzimleri

Kaynakça

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