BibTex RIS Kaynak Göster

Estrogen and progesteron receptor expression in cellular leiomyomas and leiomyosarcomas

Yıl 2003, Cilt: 34 Sayı: 4, 19 - 21, 01.05.2003

Gözde Kır Handan Çetiner Ayşe Gürbüz Sadiye Eren

Öz

Objective:To evaluate estrogen(ER) and progesteron(PR) receptor expression in cellular leiomyomas and leiomyosarcomas Materials and Methods: The study includes 17 cases of cellular leiomyoma(CM) and 7 cases of leiomyosarcoma(LMS) which were diagnosed in Pathology Department of Zeynep Kamil Hoşpital between 1997 and 2003 years. One paraffin-embedded tümör tissue per each case were analyzed immunohistochemically for ER and PR ,receptors. Results: None of LMSs showed 'overexpression' for PR. Out-of 17 CMs 13 showed PR overexpression.(LMS PR overexpressionxCMPR overexpression,p

Anahtar Kelimeler

Leiomyoma Leiomyosarcoma Receptors Estrogen Receptors Progesterone

Kaynakça

  • 1. Zaloudek CJ, Hendrickson MR. Mesenchymal tumors of the uterus. In: Kurman RJ, ed. Blaustein's Pathology of Female Genital Tract. 5th ed. New York: Springer-Verlag 2 002: 561-616
  • 2. Buttrom VC, Reiter RC. Uterine leiomyomata: etiology symptomatology and management. Fertil Steril 1981, 36:433-5
  • 3. Kamaguchi K, Fujii S, Konishi I, Nanbu Y, Nonogaki H, Mori T. Mitotik activity in uterine leimyoma during the menstrual cycle. Am J Obstet Gynecoll989; 160: 637-41
  • 4. Kawaguchi K, Fujii S, Konishi I, et al
  • Immunohistochemical analysis of oestrogen receptors, progesterone receptors and Ki-67 in leiomyoma and myometrium during the menstruial cycle and pregnancy. Virchoows Arch PatholAnat 1991, 419: 309-15
  • 5. Brandon DD, Bethea CL, Strawn EY, et al
  • Progesterone receptor messenger ribonucleic acid and protein are overexpresses in human uterine leiomyomas. Am ] Obstet Gynecol 1993; 169: 78- 85
  • 6. Mittal K, Popiolek D, Demopoulos Rl. Uterine myxoid leiomyosarcoma within a leiomyoma. Human Pathol 2000; 31: 398-400
  • 7. Scurry}, FRCPA, Hack M. Leiomyosarcoma arising in a lipoleiomyosarcoma. Gynecol Oncol 1990; 39: 381-3
  • 8. Montague A, Swariz DP, Woodruff JD. Sarcoma arising in leiomyoma of uterus. Am J Obstet Gynecol 1965; 92: 421-7
  • 9. Hendrickson MR, Kempson RL. Pure mesenchymal neoplasms of the uterine corpus. In; FoxH, Wells M. Eds. Obstetrical and Gynecological Pathology. Vol 1. 5th edn. Edinburg, London ; Churchill Livingstone; 2003 : 497-548
  • 10. Carcangiu ML, Chambers JT, VaynickIM, Pino M, Schwartz PE. Immunhis to chemical evaluation of estrogen and progesterone receptor content in 183 patients with endometrial carcinoma. Part I: clinical and histologic correlations. Am J Clin Pathol 1990; 94: 247-54
  • 11. Kounelis S, Kapranos N, Kouri E. Et al
  • Immuno his to chemical profile of endometrial adenocarcinoma: astudy of 61 cases and review of the literature. Mod Pathol 2000; 13: 379-88
  • 12. Pertschuk LP, Masood S, Simone J. et al Estrogen receptor immuno cytochemistry in endometrial carcinoma: a prognostic marker for survival. Gynecol Oncol 1996; 63: 28-33
  • 13. Fukuda K, MoriM, Uchiyama M, IwaiK, Iwasaka T, Sugimori H. Prognostic significance of progesterone receptor immuno his to chemistry in endometrial carcinoma. Gynecol Oncol 1998; 69: 220-5
  • 14. Sivridis E, GiatromanolakiA, Koukourakis M, Anastasiadis P. Endometrial carcinoma: association with low angiogenesis andbcl-2 expression. Vfrhows Arch 2001; 438: 470-7
  • 15. IwaiK, Fukuda K, Hachisuga T. Etal. Prognostic signicance of progesterone receptor immunohistochemistry for lymph node metastases in endometrial carcinoma. Gynecol Oncol 1999; 72: 351-9
  • 16. ZhaiYL, KobayashiY, Mori A et al. Expression of steroid receptors, Ki-67 and p 53 in uterine leiomyosarcomas. IntJ Gynecol Pathol 1999; 18: 20-8
  • 17. Mittal K, Demopoulos RI. MIB-1 (Ki-67), p 53, estrogen receptor and progesterone receptor expression in uterine smooth muscle tumors. Hum Pathol 2001; 32: 984-7

Selüler leiomyon ve leiomyosarkomlarda östrojen ve progesteron reseptör ekspresyonu

Yıl 2003, Cilt: 34 Sayı: 4, 19 - 21, 01.05.2003

Gözde Kır Handan Çetiner Ayşe Gürbüz Sadiye Eren

Öz

Amaç: Selüler leiomyom ve leimyo sarkomların Ostrojen ve progesteron reseptör ekspresyonlarını değerlendirmek. Materyal ve Method: 1997-2003 yıUarı arasında Zeynep Kamil Hastanesi Patoloji Bölümünde tanı almış 17 selüler leimyom ve 7 leiomyosarkom olgusu çalışma kapsamına alındı. Tümörleri temsil eden birer parafin blokda immunhisto kimyasal yöntemle östrojen ve progesteron reseptör boyanması incelendi. Bulgular: Leiomy'Osarkomların hiçbirinde progesteron resptörü için "overexpression"'(OE) izlenmedi. Onyedi adet selüler leibmyomun 13 ünde OE saptandı (LMS PR-OE x SM PR-OE, p

Anahtar Kelimeler

Leyomiyom Leyomiyosarkom Reseptörler östrojen Reseptörler progesteron

Kaynakça

  • 1. Zaloudek CJ, Hendrickson MR. Mesenchymal tumors of the uterus. In: Kurman RJ, ed. Blaustein's Pathology of Female Genital Tract. 5th ed. New York: Springer-Verlag 2 002: 561-616
  • 2. Buttrom VC, Reiter RC. Uterine leiomyomata: etiology symptomatology and management. Fertil Steril 1981, 36:433-5
  • 3. Kamaguchi K, Fujii S, Konishi I, Nanbu Y, Nonogaki H, Mori T. Mitotik activity in uterine leimyoma during the menstrual cycle. Am J Obstet Gynecoll989; 160: 637-41
  • 4. Kawaguchi K, Fujii S, Konishi I, et al
  • Immunohistochemical analysis of oestrogen receptors, progesterone receptors and Ki-67 in leiomyoma and myometrium during the menstruial cycle and pregnancy. Virchoows Arch PatholAnat 1991, 419: 309-15
  • 5. Brandon DD, Bethea CL, Strawn EY, et al
  • Progesterone receptor messenger ribonucleic acid and protein are overexpresses in human uterine leiomyomas. Am ] Obstet Gynecol 1993; 169: 78- 85
  • 6. Mittal K, Popiolek D, Demopoulos Rl. Uterine myxoid leiomyosarcoma within a leiomyoma. Human Pathol 2000; 31: 398-400
  • 7. Scurry}, FRCPA, Hack M. Leiomyosarcoma arising in a lipoleiomyosarcoma. Gynecol Oncol 1990; 39: 381-3
  • 8. Montague A, Swariz DP, Woodruff JD. Sarcoma arising in leiomyoma of uterus. Am J Obstet Gynecol 1965; 92: 421-7
  • 9. Hendrickson MR, Kempson RL. Pure mesenchymal neoplasms of the uterine corpus. In; FoxH, Wells M. Eds. Obstetrical and Gynecological Pathology. Vol 1. 5th edn. Edinburg, London ; Churchill Livingstone; 2003 : 497-548
  • 10. Carcangiu ML, Chambers JT, VaynickIM, Pino M, Schwartz PE. Immunhis to chemical evaluation of estrogen and progesterone receptor content in 183 patients with endometrial carcinoma. Part I: clinical and histologic correlations. Am J Clin Pathol 1990; 94: 247-54
  • 11. Kounelis S, Kapranos N, Kouri E. Et al
  • Immuno his to chemical profile of endometrial adenocarcinoma: astudy of 61 cases and review of the literature. Mod Pathol 2000; 13: 379-88
  • 12. Pertschuk LP, Masood S, Simone J. et al Estrogen receptor immuno cytochemistry in endometrial carcinoma: a prognostic marker for survival. Gynecol Oncol 1996; 63: 28-33
  • 13. Fukuda K, MoriM, Uchiyama M, IwaiK, Iwasaka T, Sugimori H. Prognostic significance of progesterone receptor immuno his to chemistry in endometrial carcinoma. Gynecol Oncol 1998; 69: 220-5
  • 14. Sivridis E, GiatromanolakiA, Koukourakis M, Anastasiadis P. Endometrial carcinoma: association with low angiogenesis andbcl-2 expression. Vfrhows Arch 2001; 438: 470-7
  • 15. IwaiK, Fukuda K, Hachisuga T. Etal. Prognostic signicance of progesterone receptor immunohistochemistry for lymph node metastases in endometrial carcinoma. Gynecol Oncol 1999; 72: 351-9
  • 16. ZhaiYL, KobayashiY, Mori A et al. Expression of steroid receptors, Ki-67 and p 53 in uterine leiomyosarcomas. IntJ Gynecol Pathol 1999; 18: 20-8
  • 17. Mittal K, Demopoulos RI. MIB-1 (Ki-67), p 53, estrogen receptor and progesterone receptor expression in uterine smooth muscle tumors. Hum Pathol 2001; 32: 984-7
Toplam 20 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Makaleler
Yazarlar

Gözde Kır Bu kişi benim

Handan Çetiner Bu kişi benim

Ayşe Gürbüz Bu kişi benim

Sadiye Eren Bu kişi benim

Yayımlanma Tarihi 1 Mayıs 2003
Yayımlandığı Sayı Yıl 2003 Cilt: 34 Sayı: 4

Kaynak Göster

APA Kır, G., Çetiner, H., Gürbüz, A., Eren, S. (2003). Selüler leiomyon ve leiomyosarkomlarda östrojen ve progesteron reseptör ekspresyonu. Zeynep Kamil Tıp Bülteni, 34(4), 19-21. https://doi.org/10.16948/zktb.87506
AMA Kır G, Çetiner H, Gürbüz A, Eren S. Selüler leiomyon ve leiomyosarkomlarda östrojen ve progesteron reseptör ekspresyonu. Zeynep Kamil Tıp Bülteni. Mayıs 2003;34(4):19-21. doi:10.16948/zktb.87506
Chicago Kır, Gözde, Handan Çetiner, Ayşe Gürbüz, ve Sadiye Eren. “Selüler Leiomyon Ve Leiomyosarkomlarda östrojen Ve Progesteron reseptör Ekspresyonu”. Zeynep Kamil Tıp Bülteni 34, sy. 4 (Mayıs 2003): 19-21. https://doi.org/10.16948/zktb.87506.
EndNote Kır G, Çetiner H, Gürbüz A, Eren S (01 Mayıs 2003) Selüler leiomyon ve leiomyosarkomlarda östrojen ve progesteron reseptör ekspresyonu. Zeynep Kamil Tıp Bülteni 34 4 19–21.
IEEE G. Kır, H. Çetiner, A. Gürbüz, ve S. Eren, “Selüler leiomyon ve leiomyosarkomlarda östrojen ve progesteron reseptör ekspresyonu”, Zeynep Kamil Tıp Bülteni, c. 34, sy. 4, ss. 19–21, 2003, doi: 10.16948/zktb.87506.
ISNAD Kır, Gözde vd. “Selüler Leiomyon Ve Leiomyosarkomlarda östrojen Ve Progesteron reseptör Ekspresyonu”. Zeynep Kamil Tıp Bülteni 34/4 (Mayıs 2003), 19-21. https://doi.org/10.16948/zktb.87506.
JAMA Kır G, Çetiner H, Gürbüz A, Eren S. Selüler leiomyon ve leiomyosarkomlarda östrojen ve progesteron reseptör ekspresyonu. Zeynep Kamil Tıp Bülteni. 2003;34:19–21.
MLA Kır, Gözde vd. “Selüler Leiomyon Ve Leiomyosarkomlarda östrojen Ve Progesteron reseptör Ekspresyonu”. Zeynep Kamil Tıp Bülteni, c. 34, sy. 4, 2003, ss. 19-21, doi:10.16948/zktb.87506.
Vancouver Kır G, Çetiner H, Gürbüz A, Eren S. Selüler leiomyon ve leiomyosarkomlarda östrojen ve progesteron reseptör ekspresyonu. Zeynep Kamil Tıp Bülteni. 2003;34(4):19-21.