Diagnostic tests in allergy skin tests, IgE and Specific IgE

Yıl 2010, Cilt: 41 Sayı: 2, 87 - 94, 01.03.2010

Levent Midyat

Öz

The prevalence of allergic diseases has been increasing in recent years, and therefore it is very important to evaluate these patients with appopriate diagnostic tests. Taking a detailed, comprehensive history, and performing a good physical examination of the patient, are the first steps in diagnosing the patient. After the history and physical examination, ordering the appropriate diagnostic tests, and clinical evaluation of the results of these tests are very important. In diagnosing an allergic patient, mainly there are two types of tests; in vitro and in vivo. Serum total IgE, specific IgE, eosinophil count and basophil mediator secretion test are the basic in vitro tests, while skin prick tests and provocation tests are the main in vivo tests.

Anahtar Kelimeler

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Alerjide tanısal testler deri testleri, IgE ve Spesifik IgE

Öz

Son yıllarda alerjik hastalıkların sıklığının giderek artması nedeniyle, tanısal yaklaşım da büyük önem kazanmaktadır. Alerjik hastalıkların tanısında, tüm hastalıklar da olduğu gibi ilk basamak, hastanın semptomlarının ayrıntılı sorgulandığı iyi bir öykü alınması ve özellikle alerjik hastalıkların klinik belirtilerinin arandığı sistemik bir muayenenin yapılmasıdır. Öykü ve fizik muayene sonrasında uygun laboratuar testlerinin istenmesi ve bunların klinik yorumu son derece önemlidir. Alerjik hastalıkların tanısında kullanılan testler, invitro ve invivo testler olarak iki gruba ayrılabilinir. İnvitro testler, başlıca serum total IgE, spesifik IgE, eozinofil sayımları ve bazofil mediyatör salgılama testi gibi hücresel testler, invivo testler ise, başlıca deri testleri ve provokasyon testlerinden oluşmaktadır

Anahtar Kelimeler

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Kaynakça

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