Araştırma Makalesi
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CLINICAL EXPERIENCE IN PERIPARTUM AND POSTPARTUM BLOOD TRANSFUSION PATIENTS

Yıl 2020, Cilt 51, Sayı 1, 31 - 34, 15.01.2020
https://doi.org/10.16948/zktipb.500935

Öz

Objective: We aimed to discuss the indications of blood and blood products transfusion in prepartum, peripartum and postpartum period who delivered in our obstetric clinic.

Materials – Methods: A retrospective, observational study was performed of the patients who were delivered and received blood transfusion, at the Department of Obstetrics and Gynecology of Sancaktepe Training and Research Hospital between 01 February 2018 - 31 October 2018. Data abstracted included demographic features, birth records, time of blood transfusions, indications and results.

Results: During the study period, the records of 3575 patients who delivered in our clinic, were examined. Blood transfusion was performed in 2,65% (n:95) of the patients. Blood transfusion was performed in 5,41% of deliveries by cesarean section and 1,56% in vaginal deliveries. No specific indications for transfusion were identified in 26,3% (n:25) of the patients and 30,5% patients  (n:29) had no risk factors except chronic anemia. The most common obstetric indication  was uterine atony 18,9% (n:18) of the patients. The red blood cells ratio used in the transfused patients was 2,09 ± 1,18 (0-7) units, the fresh frozen plasma ratio was 1,49 ± 1,05 (0-4) units.

Conclusion: Blood and blood products transfusions are life-saving therapies, but they can also cause undesirable complications. We believe that transfusion rates can be reduced by preventing the anemia in pregnancy with appropriate iron and multivitamin supplements by ensuring the regular follow-up of pregnant patients. 

Kaynakça

  • KAYNAKLAR1.Gulumser C, Engin-Ustun Y, Keskin L, Celen S, Sanisoglu S, Karaahmetoglu S, Ozcan A, Sencan I. Maternal mortality due to hemorrhage: population-based study in Turkey J Matern Fetal Neonatal Med. 2018 Jun11:1-72. Balki M, Dhumne S, Kasodekar S, JCA Carvalho. Blood transfusion for primary postpartum hemorrhage: a tertiary care hospital review J ObstetGynaecol Can. 2008;30:1002–7.3. Chawla S, Bal MHK, Vardhan BS, Jose CTBlood Transfusion Practices in Obstetrics: Our Experience J Obstet Gynaecol India. 2018 Jun;68(3):204-2074. Butwick AJ, Aleshi P, Fontaine M, Riley ET, Goodnough LT. retrospective analysis of transfusion outcomes in pregnant patients at tertiary obstetric center. Int J Obstet Anesth. 2009 Oct;18(4):302-8.5. Shander A, Javidroozi M, Ozawa S et al. What is really dangerous: anaemia or transfusion? Br J Anaesth2011; 107(Suppl 1): 141–159.6. Lalonde A. Prevention and treatment of postpartum hemorrhage in low-resource settings. Int J Gynaecol Obstet. 2012 May;117(2):108-187. American College of Obstetricians and Gynecologists Practice Bulletin: Clinical management guidelines for obstetrician-gynecologists Number 76, October 2006: postpartum hemorrhage. Obstet Gynecol 2006;108:1039-47.8. Stones RW, Paterson CM, Saunders NJ. Risk factors for major obstetric haemorrhage. Eur J Obstet Gynaecol 1993;168: 1443–1448.9. Stephens B, Sethna F, Crispin P. Postpartum obstetric red cell transfusion practice: A retrospective study in a tertiary obstetric centre. Aust N Z J Obstet Gynaecol. 2018 Apr;58(2):170-17710. O'Brien KL, Shainker SA, Lockhart EL. Transfusion Management of Obstetric Hemorrhage. Transfus Med Rev. 2018 Oct;32(4):249-255.11.Carroli G, Cuesta C, Abalos E, Gulmezoglu AM. Epidemiology of postpartum haemorrhage: a systematic review. Best PractResClinObstetGynaecol. 2008 Dec;22(6):999-101212. Anderson JM, Etches D.Prevention and management of postpartum hemorrhage. Am Fam Physician. 2007 Mar 15;75(6):875-8213.Neill A, Thornton S. Secondary postpartum haemorr¬hage. J Obstet Gyanecol 2002;22:119-22.14. Centers for Disease Control (CDC). CDC criteria for anemia in children and childbearing- aged women. MMWR Morb Mortal Wkly Rep1989;38(22):400-4.15. World Health Organization. Iron deficiency anaemia assessment prevention and control: a guide for programme managers. Geneva: World Health Organization; 2001;132 16. Abriha A, Yesuf ME, Wassie MM. Prevalence and associated factors of anemia among pregnant women of Mekelletown: a cross sectional study. BMC Res Notes 2014;7:888.17. Maternity care : what is needed for safer motherhood in the community? World Health Organization. Maternal Health and Safe Motherhood Programme. Safe Mother.1992;8:6-8. 18. World Health Organization. Worldwide prevalence of anaemia 1993 – 2005. WHO Global Database on Anaemia. Geneva: World Health Organization; 2008 19. Api O, Bayer F, Akıl A, Bektaş M, Api M, Dabak R, et al. The etiologic and demographicFactors related to anemia prevalence in the pregnant women admitting to an education and research hospital in Istanbul. Perinatoloji Dergisi 2009;17(1):28-33.20. Tunç SY, Görük NY, Ceylan B, Tunç N. The relationship between gestation and iron deficiency anemia in women applied to gynecologic outpatient clinic. J Clin Exp Invest 2012;38(1):49-52.21. Malhotra M, Sharma J, Batra S et al. Maternal and perinatal outcome in varying degrees of anemia. Int J Gynaecol Obstet 2002; 79:93–100.22. Vasudev R, Sawhney V, Dogra M, Raina TR. Transfusion-related adverse reactions: From institutional hemovigilance effort to National Hemovigilance program. Asian J Transfus Sci. 2016 Jan-Jun;10(1):31-623. Santoso JT, Saunders BA, Grosshart K. Massive blood loss and transfusion in obstetrics and gynecology. Obstet Gynecol Surv. 2005 Dec;60(12):827-3724. Treml AB, Gorlin JB, Dutton RP, Scavone BM. Massive Transfusion Protocols: A Survey of Academic Medical Centers in the United States Anesth Analg. 2017 Jan;124(1):277-28125. Bingham D, Lyndon A, Lagrew D, Main EK. A state-wide obstetric hemorrhage quality improvement initiative. Am J Matern Child Nurs. 2011 Sep-Oct;36(5):297-304 26. Vachhani JH, Joshi JR, Bhanvadia VM. Rational use of blood: a study report on single unit transfusion Indian J Hematol Blood Transfus. 2008 Jun;24(2):69-71

PERİPARTUM VE POSTPARTUM KAN TRANSFÜZYONU YAPILAN HASTALARDA KLİNİK DENEYİMLERİMİZ

Yıl 2020, Cilt 51, Sayı 1, 31 - 34, 15.01.2020
https://doi.org/10.16948/zktipb.500935

Öz

Amaç:  Kliniğimizde doğum yapan hastaların prepartum, peripartum ve postpartum dönemdeki kan ve kan ürünleri transfüzyon endikasyonlarını literatür eşliğinde tartışmak.

Materyal- Metod: Sancaktepe Şehit Prof.Dr.İlhan Varank   Eğitim ve Araştırma Hastanesi, Kadın Hastalıkları ve Doğum Kliniği,  01 Şubat 2018-31 Ekim 2018 tarihleri arasında doğum yapan ve kan transfüzyonu yapılan hastaların demografik özellikleri, doğum kayıtları,  kan transfüzyonu zamanı, endikasyonları ve sonuçlarının incelendiği retrospektif gözlemsel bir çalışma yapılmıştır.

Bulgular: Çalışma süresince kliniğimizde doğum yapan 3575 hastanın kayıtları incelenmiştir. Hastaların %2,65’ine (n­:95) kan transfüzyonu yapılmıştır. Sezaryen ile doğumların %5,41’ inde, vajinal doğumların ise %1,56’sında kan transfüzyonu uygulanmıştır. Transfüzyon yapılan hastaların  %26,3‘inde (n:25)  herhangi bir spesifik neden belirtilmez iken %30,5 (n:29) hastada ek risk faktörü olmayıp transfüzyon endikasyonu kronik anemi bulunmuştur. Obstetrik endikasyonlardan en sık uterin atoni %18,9 (n:18) saptanmıştır. Transfüzyon yapılan hastalarda kullanılanan kan ürünleriden eritrosit süspansiyonu ortalama 2,09 ± 1,186 (0-7) ünite, TDP 1,49 ± 1,05 (0-4) ünite uygulanmıştır.

Sonuç: Kan ve kan ürünleri transfüzyonları hayat kurtarıcı tedaviler olmakla beraber istenmeyen komplikasyonlara da neden olabilirler.  Gebe hastaların izlem ve takiplerinin düzenli yapılması sağlanarak uygun demir ve multivitamin takviyeleri ile gebelikte anemiyi önleyerek transfüzyon oranlarının düşürülebileceğini düşünüyoruz. 

Kaynakça

  • KAYNAKLAR1.Gulumser C, Engin-Ustun Y, Keskin L, Celen S, Sanisoglu S, Karaahmetoglu S, Ozcan A, Sencan I. Maternal mortality due to hemorrhage: population-based study in Turkey J Matern Fetal Neonatal Med. 2018 Jun11:1-72. Balki M, Dhumne S, Kasodekar S, JCA Carvalho. Blood transfusion for primary postpartum hemorrhage: a tertiary care hospital review J ObstetGynaecol Can. 2008;30:1002–7.3. Chawla S, Bal MHK, Vardhan BS, Jose CTBlood Transfusion Practices in Obstetrics: Our Experience J Obstet Gynaecol India. 2018 Jun;68(3):204-2074. Butwick AJ, Aleshi P, Fontaine M, Riley ET, Goodnough LT. retrospective analysis of transfusion outcomes in pregnant patients at tertiary obstetric center. Int J Obstet Anesth. 2009 Oct;18(4):302-8.5. Shander A, Javidroozi M, Ozawa S et al. What is really dangerous: anaemia or transfusion? Br J Anaesth2011; 107(Suppl 1): 141–159.6. Lalonde A. Prevention and treatment of postpartum hemorrhage in low-resource settings. Int J Gynaecol Obstet. 2012 May;117(2):108-187. American College of Obstetricians and Gynecologists Practice Bulletin: Clinical management guidelines for obstetrician-gynecologists Number 76, October 2006: postpartum hemorrhage. Obstet Gynecol 2006;108:1039-47.8. Stones RW, Paterson CM, Saunders NJ. Risk factors for major obstetric haemorrhage. Eur J Obstet Gynaecol 1993;168: 1443–1448.9. Stephens B, Sethna F, Crispin P. Postpartum obstetric red cell transfusion practice: A retrospective study in a tertiary obstetric centre. Aust N Z J Obstet Gynaecol. 2018 Apr;58(2):170-17710. O'Brien KL, Shainker SA, Lockhart EL. Transfusion Management of Obstetric Hemorrhage. Transfus Med Rev. 2018 Oct;32(4):249-255.11.Carroli G, Cuesta C, Abalos E, Gulmezoglu AM. Epidemiology of postpartum haemorrhage: a systematic review. Best PractResClinObstetGynaecol. 2008 Dec;22(6):999-101212. Anderson JM, Etches D.Prevention and management of postpartum hemorrhage. Am Fam Physician. 2007 Mar 15;75(6):875-8213.Neill A, Thornton S. Secondary postpartum haemorr¬hage. J Obstet Gyanecol 2002;22:119-22.14. Centers for Disease Control (CDC). CDC criteria for anemia in children and childbearing- aged women. MMWR Morb Mortal Wkly Rep1989;38(22):400-4.15. World Health Organization. Iron deficiency anaemia assessment prevention and control: a guide for programme managers. Geneva: World Health Organization; 2001;132 16. Abriha A, Yesuf ME, Wassie MM. Prevalence and associated factors of anemia among pregnant women of Mekelletown: a cross sectional study. BMC Res Notes 2014;7:888.17. Maternity care : what is needed for safer motherhood in the community? World Health Organization. Maternal Health and Safe Motherhood Programme. Safe Mother.1992;8:6-8. 18. World Health Organization. Worldwide prevalence of anaemia 1993 – 2005. WHO Global Database on Anaemia. Geneva: World Health Organization; 2008 19. Api O, Bayer F, Akıl A, Bektaş M, Api M, Dabak R, et al. The etiologic and demographicFactors related to anemia prevalence in the pregnant women admitting to an education and research hospital in Istanbul. Perinatoloji Dergisi 2009;17(1):28-33.20. Tunç SY, Görük NY, Ceylan B, Tunç N. The relationship between gestation and iron deficiency anemia in women applied to gynecologic outpatient clinic. J Clin Exp Invest 2012;38(1):49-52.21. Malhotra M, Sharma J, Batra S et al. Maternal and perinatal outcome in varying degrees of anemia. Int J Gynaecol Obstet 2002; 79:93–100.22. Vasudev R, Sawhney V, Dogra M, Raina TR. Transfusion-related adverse reactions: From institutional hemovigilance effort to National Hemovigilance program. Asian J Transfus Sci. 2016 Jan-Jun;10(1):31-623. Santoso JT, Saunders BA, Grosshart K. Massive blood loss and transfusion in obstetrics and gynecology. Obstet Gynecol Surv. 2005 Dec;60(12):827-3724. Treml AB, Gorlin JB, Dutton RP, Scavone BM. Massive Transfusion Protocols: A Survey of Academic Medical Centers in the United States Anesth Analg. 2017 Jan;124(1):277-28125. Bingham D, Lyndon A, Lagrew D, Main EK. A state-wide obstetric hemorrhage quality improvement initiative. Am J Matern Child Nurs. 2011 Sep-Oct;36(5):297-304 26. Vachhani JH, Joshi JR, Bhanvadia VM. Rational use of blood: a study report on single unit transfusion Indian J Hematol Blood Transfus. 2008 Jun;24(2):69-71

Ayrıntılar

Birincil Dil Türkçe
Konular Sağlık Bilimleri ve Hizmetleri
Bölüm Orjinal Araştırma
Yazarlar

Elcin İSLEK SECEN (Sorumlu Yazar)
İSTANBUL SANCAKTEPE ŞEHİT PROF.DR.İLHAN VARANK EĞİTİM VE ARAŞTIRMA HASTANESİ
Türkiye


Mehmet Akif SARGIN Bu kişi benim
İSTANBUL SANCAKTEPE ŞEHİT PROF.DR.İLHAN VARANK EĞİTİM VE ARAŞTIRMA HASTANESİ


Esra ÇAMURŞEN Bu kişi benim
İSTANBUL SANCAKTEPE ŞEHİT PROF.DR.İLHAN VARANK EĞİTİM VE ARAŞTIRMA HASTANESİ


İdris YETİMOĞLU Bu kişi benim
İSTANBUL SANCAKTEPE ŞEHİT PROF.DR.İLHAN VARANK EĞİTİM VE ARAŞTIRMA HASTANESİ


Özge KAYMAZ YILMAZ Bu kişi benim
İSTANBUL SANCAKTEPE ŞEHİT PROF.DR.İLHAN VARANK EĞİTİM VE ARAŞTIRMA HASTANESİ


Niyazi TUĞ Bu kişi benim
İSTANBUL SANCAKTEPE ŞEHİT PROF.DR.İLHAN VARANK EĞİTİM VE ARAŞTIRMA HASTANESİ

Yayımlanma Tarihi 15 Ocak 2020
Yayınlandığı Sayı Yıl 2020, Cilt 51, Sayı 1

Kaynak Göster

Bibtex @araştırma makalesi { zktipb500935, journal = {Zeynep Kamil Tıp Bülteni}, issn = {1300-7971}, eissn = {2148-4864}, address = {}, publisher = {Zeynep Kamil Kadın ve Çocuk Hastalıkları EAH}, year = {2020}, volume = {51}, pages = {31 - 34}, doi = {10.16948/zktipb.500935}, title = {PERİPARTUM VE POSTPARTUM KAN TRANSFÜZYONU YAPILAN HASTALARDA KLİNİK DENEYİMLERİMİZ}, key = {cite}, author = {İslek Secen, Elcin and Sargın, Mehmet Akif and Çamurşen, Esra and Yetimoğlu, İdris and Kaymaz Yılmaz, Özge and Tuğ, Niyazi} }
APA İslek Secen, E. , Sargın, M. A. , Çamurşen, E. , Yetimoğlu, İ. , Kaymaz Yılmaz, Ö. & Tuğ, N. (2020). PERİPARTUM VE POSTPARTUM KAN TRANSFÜZYONU YAPILAN HASTALARDA KLİNİK DENEYİMLERİMİZ . Zeynep Kamil Tıp Bülteni , 51 (1) , 31-34 . DOI: 10.16948/zktipb.500935
MLA İslek Secen, E. , Sargın, M. A. , Çamurşen, E. , Yetimoğlu, İ. , Kaymaz Yılmaz, Ö. , Tuğ, N. "PERİPARTUM VE POSTPARTUM KAN TRANSFÜZYONU YAPILAN HASTALARDA KLİNİK DENEYİMLERİMİZ" . Zeynep Kamil Tıp Bülteni 51 (2020 ): 31-34 <https://dergipark.org.tr/tr/pub/zktipb/issue/52318/500935>
Chicago İslek Secen, E. , Sargın, M. A. , Çamurşen, E. , Yetimoğlu, İ. , Kaymaz Yılmaz, Ö. , Tuğ, N. "PERİPARTUM VE POSTPARTUM KAN TRANSFÜZYONU YAPILAN HASTALARDA KLİNİK DENEYİMLERİMİZ". Zeynep Kamil Tıp Bülteni 51 (2020 ): 31-34
RIS TY - JOUR T1 - PERİPARTUM VE POSTPARTUM KAN TRANSFÜZYONU YAPILAN HASTALARDA KLİNİK DENEYİMLERİMİZ AU - Elcin İslek Secen , Mehmet Akif Sargın , Esra Çamurşen , İdris Yetimoğlu , Özge Kaymaz Yılmaz , Niyazi Tuğ Y1 - 2020 PY - 2020 N1 - doi: 10.16948/zktipb.500935 DO - 10.16948/zktipb.500935 T2 - Zeynep Kamil Tıp Bülteni JF - Journal JO - JOR SP - 31 EP - 34 VL - 51 IS - 1 SN - 1300-7971-2148-4864 M3 - doi: 10.16948/zktipb.500935 UR - https://doi.org/10.16948/zktipb.500935 Y2 - 2019 ER -
EndNote %0 Zeynep Kamil Tıp Bülteni PERİPARTUM VE POSTPARTUM KAN TRANSFÜZYONU YAPILAN HASTALARDA KLİNİK DENEYİMLERİMİZ %A Elcin İslek Secen , Mehmet Akif Sargın , Esra Çamurşen , İdris Yetimoğlu , Özge Kaymaz Yılmaz , Niyazi Tuğ %T PERİPARTUM VE POSTPARTUM KAN TRANSFÜZYONU YAPILAN HASTALARDA KLİNİK DENEYİMLERİMİZ %D 2020 %J Zeynep Kamil Tıp Bülteni %P 1300-7971-2148-4864 %V 51 %N 1 %R doi: 10.16948/zktipb.500935 %U 10.16948/zktipb.500935
ISNAD İslek Secen, Elcin , Sargın, Mehmet Akif , Çamurşen, Esra , Yetimoğlu, İdris , Kaymaz Yılmaz, Özge , Tuğ, Niyazi . "PERİPARTUM VE POSTPARTUM KAN TRANSFÜZYONU YAPILAN HASTALARDA KLİNİK DENEYİMLERİMİZ". Zeynep Kamil Tıp Bülteni 51 / 1 (Ocak 2020): 31-34 . https://doi.org/10.16948/zktipb.500935
AMA İslek Secen E. , Sargın M. A. , Çamurşen E. , Yetimoğlu İ. , Kaymaz Yılmaz Ö. , Tuğ N. PERİPARTUM VE POSTPARTUM KAN TRANSFÜZYONU YAPILAN HASTALARDA KLİNİK DENEYİMLERİMİZ. Zeynep Kamil Tıp Bülteni. 2020; 51(1): 31-34.
Vancouver İslek Secen E. , Sargın M. A. , Çamurşen E. , Yetimoğlu İ. , Kaymaz Yılmaz Ö. , Tuğ N. PERİPARTUM VE POSTPARTUM KAN TRANSFÜZYONU YAPILAN HASTALARDA KLİNİK DENEYİMLERİMİZ. Zeynep Kamil Tıp Bülteni. 2020; 51(1): 31-34.
IEEE E. İslek Secen , M. A. Sargın , E. Çamurşen , İ. Yetimoğlu , Ö. Kaymaz Yılmaz ve N. Tuğ , "PERİPARTUM VE POSTPARTUM KAN TRANSFÜZYONU YAPILAN HASTALARDA KLİNİK DENEYİMLERİMİZ", Zeynep Kamil Tıp Bülteni, c. 51, sayı. 1, ss. 31-34, Oca. 2020, doi:10.16948/zktipb.500935