Research Article

Comparison of the effects of isokinetic exercise system and home exercise program on balance, gait analysis, pain severity and quality of life in patients with bilateral knee osteoarthritis

Volume: 8 Number: 2 March 10, 2026

Comparison of the effects of isokinetic exercise system and home exercise program on balance, gait analysis, pain severity and quality of life in patients with bilateral knee osteoarthritis

Abstract

Aims: Our aim in this study is to compare the effects of isokinetic exercise system and home based exercise program on balance and gait analysis, pain severity and quality of life in patients with knee osteoarthritis (OA). Methods: A total of 60 patients diagnosed with primary knee OA were included in the study. The patients were divided into two groups. The first group received conventional electrotherapy for 10 sessions along with a six-week home-based program consisting of isometric and isotonic strengthening exercises targeting the knee flexor and extensor muscles, performed three times per week. The second group received conventional electrotherapy for 10 sessions combined with a six-week isokinetic strengthening program targeting the knee flexor and extensor muscles, performed three times per week under the supervision of a physiotherapist. At the beginning and end of the treatment, patients were evaluated using the Visual Analog Scale (VAS), the Western Ontario and McMaster Universities Arthritis Index (WOMAC), the Short Form-36 (SF-36), the 6-Minute Walk Test (6-MWT), the Timed Up and Go Test (TUG), the Berg Balance Scale (BBS), and spatiotemporal gait analysis parameters (cadence, swing and stance phase percentages, stride length, step width, step time, and gait speed). Results: The isokinetic exercise group exhibited statistically significant improvements over the home exercise group in activity VAS scores, the emotional role difficulty and mental health subscales of the SF-36, and the 6-MWT distances (p<0.05). In contrast, the home exercise group demonstrated superior improvement in the physical role difficulty subscale of the SF-36 when compared to the isokinetic exercise group (p<0.05). No statistically significant differences were observed between the two groups in the other evaluated parameters (p>0.05). Conclusion: In patients with knee osteoarthritis, non-pharmacological treatment modalities that support gait and balance biomechanics have been shown to exert beneficial effects, particularly on pain and functional status; moreover, the isokinetic exercise program was found to be superior to the conventional home exercise program with respect to activity-related VAS scores, mental health parameters, and functional capacity.

Keywords

Supporting Institution

No supporting institution

Project Number

1

Ethical Statement

This study was conducted in accordance with the principles of the Declaration of Helsinki. The study protocol was approved by the Ethics Committee No. 2 of the Ministry of Health Ankara Bilkent City Hospital (approval date: February 16, 2022; decision no: E2-22-1355). Written informed consent was obtained from all participants prior to their inclusion in the study. The authors declare that they have no conflicts of interest.

Thanks

I would like to express my sincere gratitude to my family for their continuous moral and financial support, and to my wife, Dr. Merve Kahyaoğlu, for her unwavering support and understanding throughout my residency training.

References

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  2. Lange AK, Vanwanseele B, Fiatarone Singh MA. Strength training for treatment of osteoarthritis of the knee: a systematic review. Arthritis Rheum. 2008;59(10):1488-1494. doi:10.1002/art.24118
  3. Røgind H, Bibow-Nielsen B, Jensen B, Møller HC, Frimodt-Møller H, Bliddal H. The effects of a physical training program on patients with osteoarthritis of the knees. Arch Phys Med Rehabil. 1998;79(11):1421-1427. doi:10.1016/s0003-9993(98)90238-6
  4. Segal NA, Torner JC, Felson D, et al. Effect of thigh strength on incident radiographic and symptomatic knee osteoarthritis in a longitudinal cohort. Arthritis Rheum. 2009;61(9):1210-1217. doi:10.1002/art.24541
  5. McAlindon TE, Cooper C, Kirwan JR, Dieppe PA. Determinants of disability in osteoarthritis of the knee. Ann Rheum Dis. 1993;52(4):258-262. doi:10.1136/ard.52.4.258
  6. Slemenda C, Brandt KD, Heilman DK, et al. Quadriceps weakness and osteoarthritis of the knee. Ann Intern Med. 1997;127(2):97-104. doi:10. 7326/0003-4819-127-2-199707150-00001
  7. Hassan BS, Mockett S, Doherty M. Static postural sway, proprioception, and maximal voluntary quadriceps contraction in patients with knee osteoarthritis and normal control subjects. Ann Rheum Dis. 2001;60(6): 612-618. doi:10.1136/ard.60.6.612
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Details

Primary Language

English

Subjects

Physical Medicine and Rehabilitation

Journal Section

Research Article

Publication Date

March 10, 2026

Submission Date

December 25, 2025

Acceptance Date

January 29, 2026

Published in Issue

Year 2026 Volume: 8 Number: 2

APA
Kahyaoğlu, M., Varan, E., Ordu Gökkaya, N. K., & Eser, F. (2026). Comparison of the effects of isokinetic exercise system and home exercise program on balance, gait analysis, pain severity and quality of life in patients with bilateral knee osteoarthritis. Anatolian Current Medical Journal, 8(2), 210-217. https://doi.org/10.38053/acmj.1849097
AMA
1.Kahyaoğlu M, Varan E, Ordu Gökkaya NK, Eser F. Comparison of the effects of isokinetic exercise system and home exercise program on balance, gait analysis, pain severity and quality of life in patients with bilateral knee osteoarthritis. Anatolian Curr Med J / ACMJ / acmj. 2026;8(2):210-217. doi:10.38053/acmj.1849097
Chicago
Kahyaoğlu, Melih, Edip Varan, Nilüfer Kutay Ordu Gökkaya, and Filiz Eser. 2026. “Comparison of the Effects of Isokinetic Exercise System and Home Exercise Program on Balance, Gait Analysis, Pain Severity and Quality of Life in Patients With Bilateral Knee Osteoarthritis”. Anatolian Current Medical Journal 8 (2): 210-17. https://doi.org/10.38053/acmj.1849097.
EndNote
Kahyaoğlu M, Varan E, Ordu Gökkaya NK, Eser F (March 1, 2026) Comparison of the effects of isokinetic exercise system and home exercise program on balance, gait analysis, pain severity and quality of life in patients with bilateral knee osteoarthritis. Anatolian Current Medical Journal 8 2 210–217.
IEEE
[1]M. Kahyaoğlu, E. Varan, N. K. Ordu Gökkaya, and F. Eser, “Comparison of the effects of isokinetic exercise system and home exercise program on balance, gait analysis, pain severity and quality of life in patients with bilateral knee osteoarthritis”, Anatolian Curr Med J / ACMJ / acmj, vol. 8, no. 2, pp. 210–217, Mar. 2026, doi: 10.38053/acmj.1849097.
ISNAD
Kahyaoğlu, Melih - Varan, Edip - Ordu Gökkaya, Nilüfer Kutay - Eser, Filiz. “Comparison of the Effects of Isokinetic Exercise System and Home Exercise Program on Balance, Gait Analysis, Pain Severity and Quality of Life in Patients With Bilateral Knee Osteoarthritis”. Anatolian Current Medical Journal 8/2 (March 1, 2026): 210-217. https://doi.org/10.38053/acmj.1849097.
JAMA
1.Kahyaoğlu M, Varan E, Ordu Gökkaya NK, Eser F. Comparison of the effects of isokinetic exercise system and home exercise program on balance, gait analysis, pain severity and quality of life in patients with bilateral knee osteoarthritis. Anatolian Curr Med J / ACMJ / acmj. 2026;8:210–217.
MLA
Kahyaoğlu, Melih, et al. “Comparison of the Effects of Isokinetic Exercise System and Home Exercise Program on Balance, Gait Analysis, Pain Severity and Quality of Life in Patients With Bilateral Knee Osteoarthritis”. Anatolian Current Medical Journal, vol. 8, no. 2, Mar. 2026, pp. 210-7, doi:10.38053/acmj.1849097.
Vancouver
1.Melih Kahyaoğlu, Edip Varan, Nilüfer Kutay Ordu Gökkaya, Filiz Eser. Comparison of the effects of isokinetic exercise system and home exercise program on balance, gait analysis, pain severity and quality of life in patients with bilateral knee osteoarthritis. Anatolian Curr Med J / ACMJ / acmj. 2026 Mar. 1;8(2):210-7. doi:10.38053/acmj.1849097

 

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