Osteosarcopenia research, 2001-2025: worldwide bibliometric trends and consequences for clinical and public health practice
Abstract
Aims: Osteosarcopenia, the coexistence of osteoporosis and sarcopenia, is increasingly recognized as a key geriatric syndrome associated with frailty, falls, fractures, disability, and mortality. We aimed to map worldwide publication trends and thematic evolution in osteosarcopenia research.
Methods: We performed a bibliometric analysis of Web of Science Core Collection publications from 2001 to October 2025, restricted to English-language open-access articles with a geriatric and musculoskeletal focus. Analyses included annual scientific production, source and country productivity, keyword co occurrence, thematic mapping, thematic evolution, and multiple correspondence analysis (MCA).
Results: A total of 1,514 articles were identified, with a marked growth in publications after 2017. The most productive countries were China, the United States, and Japan. Core themes centered on sarcopenia, osteoporosis, bone mineral density, and muscle, while thematic analyses highlighted both clinical epidemiological domains and emerging mechanistic topics. MCA suggested a dual-axis conceptual structure linking clinical foundations with biological mechanisms.
Conclusion: Osteosarcopenia research has expanded rapidly since 2017 and evolved into a multidisciplinary domain. These findings support the need to integrate osteosarcopenia into geriatric risk stratification and preventive strategies.
Keywords
Supporting Institution
This study received no financial support from any funding agency or commercial sector.
Ethical Statement
As this study is a bibliometric analysis based on metadata from previously published literature, ethical approval was not required
Thanks
None
References
- Fried LP, Tangen CM, Walston J, et al. Cardiovascular Health Study Collaborative Research Group. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56(3):M146-M156. doi: 10.1093/gerona/56.3.m146
- Cruz-Jentoft AJ, Bahat G, Bauer J, et al. Writing Group for the EWGSOP2; Extended Group for EWGSOP2. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;48(1):16-31. doi:10.1093/ageing/afy169
- Frost HM. Bone’s mechanostat: a 2003 update. Anat Rec A Discov Mol Cell Evol Biol. 2003;275(2):1081-1101. doi:10.1002/ar.a.10119
- Wu CH, Yang KC, Chang HH, Yen JF, Tsai KS, Huang KC. Sarcopenia is related to increased risk for low bone mineral density. J Clin Densitom. 2013;16(1):98-103. doi:10.1016/j.jocd.2012.07.010
- Hassan EB, Duque G. Osteosarcopenia: a new geriatric syndrome. Aust Fam Physician. 2017;46(11):849-853.
- Hirschfeld HP, Kinsella R, Duque G. Osteosarcopenia: where bone, muscle, and fat collide. Osteoporos Int. 2017;28(10):2781-2790. doi:10. 1007/s00198-017-4151-8
- Kirk B, Zanker J, Duque G. Osteosarcopenia: epidemiology, diagnosis, and treatment-facts and numbers. J Cachexia Sarcopenia Muscle. 2020; 11(3):609-618. doi:10.1002/jcsm.12567
- Fagundes Belchior G, Kirk B, Pereira da Silva EA, Duque G. Osteosarcopenia: beyond age-related muscle and bone loss. Eur Geriatr Med. 2020;11(5):715-724. doi:10.1007/s41999-020-00355-6
Details
Primary Language
English
Subjects
Geriatrics and Gerontology, Orthopaedics, Aged Health Care
Journal Section
Research Article
Publication Date
March 10, 2026
Submission Date
January 13, 2026
Acceptance Date
February 4, 2026
Published in Issue
Year 2026 Volume: 8 Number: 2
APA
Topkaya, Y., & Kıraç Utku, İ. (2026). Osteosarcopenia research, 2001-2025: worldwide bibliometric trends and consequences for clinical and public health practice. Anatolian Current Medical Journal, 8(2), 250-256. https://doi.org/10.38053/acmj.1862614
AMA
1.Topkaya Y, Kıraç Utku İ. Osteosarcopenia research, 2001-2025: worldwide bibliometric trends and consequences for clinical and public health practice. Anatolian Curr Med J / ACMJ / acmj. 2026;8(2):250-256. doi:10.38053/acmj.1862614
Chicago
Topkaya, Yüksel, and İrem Kıraç Utku. 2026. “Osteosarcopenia Research, 2001-2025: Worldwide Bibliometric Trends and Consequences for Clinical and Public Health Practice”. Anatolian Current Medical Journal 8 (2): 250-56. https://doi.org/10.38053/acmj.1862614.
EndNote
Topkaya Y, Kıraç Utku İ (March 1, 2026) Osteosarcopenia research, 2001-2025: worldwide bibliometric trends and consequences for clinical and public health practice. Anatolian Current Medical Journal 8 2 250–256.
IEEE
[1]Y. Topkaya and İ. Kıraç Utku, “Osteosarcopenia research, 2001-2025: worldwide bibliometric trends and consequences for clinical and public health practice”, Anatolian Curr Med J / ACMJ / acmj, vol. 8, no. 2, pp. 250–256, Mar. 2026, doi: 10.38053/acmj.1862614.
ISNAD
Topkaya, Yüksel - Kıraç Utku, İrem. “Osteosarcopenia Research, 2001-2025: Worldwide Bibliometric Trends and Consequences for Clinical and Public Health Practice”. Anatolian Current Medical Journal 8/2 (March 1, 2026): 250-256. https://doi.org/10.38053/acmj.1862614.
JAMA
1.Topkaya Y, Kıraç Utku İ. Osteosarcopenia research, 2001-2025: worldwide bibliometric trends and consequences for clinical and public health practice. Anatolian Curr Med J / ACMJ / acmj. 2026;8:250–256.
MLA
Topkaya, Yüksel, and İrem Kıraç Utku. “Osteosarcopenia Research, 2001-2025: Worldwide Bibliometric Trends and Consequences for Clinical and Public Health Practice”. Anatolian Current Medical Journal, vol. 8, no. 2, Mar. 2026, pp. 250-6, doi:10.38053/acmj.1862614.
Vancouver
1.Yüksel Topkaya, İrem Kıraç Utku. Osteosarcopenia research, 2001-2025: worldwide bibliometric trends and consequences for clinical and public health practice. Anatolian Curr Med J / ACMJ / acmj. 2026 Mar. 1;8(2):250-6. doi:10.38053/acmj.1862614
