Clinical Research

The Relationship Between Variations In the Circle of Willis and Multiple Intracerebral Aneurysms

Volume: 12 Number: 1 June 26, 2026
TR EN

The Relationship Between Variations In the Circle of Willis and Multiple Intracerebral Aneurysms

Abstract

ABSTRACT Objective To investigate the association between variations in the Circle of Willis (COW) and the prevalence of multiple intracerebral aneurysms. Material and Methods This retrospective study analyzed 1,205 patients who underwent cerebral Computed Tomography Angiography at Akdeniz University between January 2013 and September 2019. We assessed the correlation between COW variations and aneurysm incidence, focusing on demographics and specific anatomical variations. Results The study identified a 21% incidence of intracerebral aneurysms, considerably higher than the typically reported 1-6%. Notably, variations such as anterior cerebral artery A1 segment aplasia were prevalent in patients with aneurysms, particularly older females. A significant association was found between these anatomical variations and the occurrence of multiple aneurysms. Conclusion Variations in the COW are significantly associated with the presence of intracerebral aneurysms. Furthermore, specific types of variation were independently associated with both single and multiple aneurysms. Our findings emphasize the importance of detailed neurovascular imaging in enhancing the detection and management of aneurysms.

Keywords

References

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Details

Primary Language

English

Subjects

Radiology and Organ Imaging

Journal Section

Clinical Research

Publication Date

June 26, 2026

Submission Date

July 21, 2025

Acceptance Date

September 17, 2025

Published in Issue

Year 2026 Volume: 12 Number: 1

APA
Kahraman, F., Özgür, Ö., Gündüz, D., Heperenler, E., & Oktay, C. (2026). The Relationship Between Variations In the Circle of Willis and Multiple Intracerebral Aneurysms. Akdeniz Tıp Dergisi, 12(1). https://doi.org/10.53394/akd.1747682
AMA
1.Kahraman F, Özgür Ö, Gündüz D, Heperenler E, Oktay C. The Relationship Between Variations In the Circle of Willis and Multiple Intracerebral Aneurysms. Akd Med J. 2026;12(1). doi:10.53394/akd.1747682
Chicago
Kahraman, Fulya, Özhan Özgür, Demet Gündüz, Erhan Heperenler, and Cemil Oktay. 2026. “The Relationship Between Variations In the Circle of Willis and Multiple Intracerebral Aneurysms”. Akdeniz Tıp Dergisi 12 (1). https://doi.org/10.53394/akd.1747682.
EndNote
Kahraman F, Özgür Ö, Gündüz D, Heperenler E, Oktay C (June 1, 2026) The Relationship Between Variations In the Circle of Willis and Multiple Intracerebral Aneurysms. Akdeniz Tıp Dergisi 12 1
IEEE
[1]F. Kahraman, Ö. Özgür, D. Gündüz, E. Heperenler, and C. Oktay, “The Relationship Between Variations In the Circle of Willis and Multiple Intracerebral Aneurysms”, Akd Med J, vol. 12, no. 1, June 2026, doi: 10.53394/akd.1747682.
ISNAD
Kahraman, Fulya - Özgür, Özhan - Gündüz, Demet - Heperenler, Erhan - Oktay, Cemil. “The Relationship Between Variations In the Circle of Willis and Multiple Intracerebral Aneurysms”. Akdeniz Tıp Dergisi 12/1 (June 1, 2026). https://doi.org/10.53394/akd.1747682.
JAMA
1.Kahraman F, Özgür Ö, Gündüz D, Heperenler E, Oktay C. The Relationship Between Variations In the Circle of Willis and Multiple Intracerebral Aneurysms. Akd Med J. 2026;12. doi:10.53394/akd.1747682.
MLA
Kahraman, Fulya, et al. “The Relationship Between Variations In the Circle of Willis and Multiple Intracerebral Aneurysms”. Akdeniz Tıp Dergisi, vol. 12, no. 1, June 2026, doi:10.53394/akd.1747682.
Vancouver
1.Fulya Kahraman, Özhan Özgür, Demet Gündüz, Erhan Heperenler, Cemil Oktay. The Relationship Between Variations In the Circle of Willis and Multiple Intracerebral Aneurysms. Akd Med J. 2026 Jun. 1;12(1). doi:10.53394/akd.1747682