Willis Poligonu Varyasyonları ile Çoklu İntraserebral Anevrizmalar Arasındaki İlişki

Öz

ÖZ Amaç Willis Poligonu (WP) varyasyonları ile çoklu intraserebral anevrizma görülme sıklığı arasındaki ilişkiyi araştırmak. Gereç ve Yöntemler Bu retrospektif çalışmada, Ocak 2013 ile Eylül 2019 tarihleri arasında Akdeniz Üniversitesinde Beyin Bilgisayarlı Tomografi Anjiyografisi yapılan 1.205 hasta analiz edildi. WP varyasyonlarının anevrizma insidansı ile olan ilişkisi; demografik veriler ve spesifik anatomik varyasyonlara odaklanılarak değerlendirildi. Bulgular Çalışmada intraserebral anevrizma insidansı %21 olarak tespit edildi; bu oran literatürde bildirilen %1-6’lık aralığın oldukça üzerindedir. Özellikle ön serebral arter A1 segmenti aplazisi gibi varyasyonlar, anevrizması olan özellikle ileri yaş kadın hastalarda daha sık görüldü. Bu anatomik varyasyonlar ile çoklu anevrizma varlığı arasında anlamlı bir ilişki saptandı. Sonuç Willis Poligonu varyasyonları ile intraserebral anevrizma varlığı arasında anlamlı bir ilişki bulunmaktadır. Ayrıca bazı spesifik varyasyon tipleri, hem tekil hem de çoklu anevrizmalarla bağımsız olarak ilişkili bulunmuştur. Bulgularımız, anevrizmaların tespiti ve yönetiminde detaylı nörovasküler görüntülemenin önemini vurgulamaktadır.

Anahtar Kelimeler

• İntraserebral anevrizma
• Willis Poligonu
• Bilgisayarlı Tomografi Anjiyografi

The Relationship Between Variations In the Circle of Willis and Multiple Intracerebral Aneurysms

Öz

ABSTRACT Objective To investigate the association between variations in the Circle of Willis (COW) and the prevalence of multiple intracerebral aneurysms. Material and Methods This retrospective study analyzed 1,205 patients who underwent cerebral Computed Tomography Angiography at Akdeniz University between January 2013 and September 2019. We assessed the correlation between COW variations and aneurysm incidence, focusing on demographics and specific anatomical variations. Results The study identified a 21% incidence of intracerebral aneurysms, considerably higher than the typically reported 1-6%. Notably, variations such as anterior cerebral artery A1 segment aplasia were prevalent in patients with aneurysms, particularly older females. A significant association was found between these anatomical variations and the occurrence of multiple aneurysms. Conclusion Variations in the COW are significantly associated with the presence of intracerebral aneurysms. Furthermore, specific types of variation were independently associated with both single and multiple aneurysms. Our findings emphasize the importance of detailed neurovascular imaging in enhancing the detection and management of aneurysms.

Anahtar Kelimeler

• Intracerebral aneurysms
• Circle of Willis
• Computed Tomography Angiography

Kaynakça

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