Antioxidative capacities of some GABAA receptor modulating food plants

Sümeyye Şahin

doi:10.29278/azd.602839

Antioxidative capacities of some GABAA receptor modulating food plants

Öz

Reactive oxygen species cause oxidative stress associated with some health issues such as neurodegenerative diseases. Some antioxidants show neuroprotective activity and regulate neuronal activity through positive modulation of GABA_A receptors. In this study, the antioxidative capacity of some novel GABA_A receptor modulating food plants, including lavender, clove and four Sideritis species (S. arguta, S. sipylea, S. condensata, and S. stricta) was investigated using ABTS assay. The aqueous clove extract showed the most potent antioxidant effect and its IC₅₀ value was found to be 3.76 μg/mL. The antioxidant capacity of Trolox was lower (IC₅₀: 4.63 μg/mL) than that of the clove extract, but higher than those of the other food extracts. The aqueous lavender extract exhibited less antioxidant activity compared to Sideritis species, except S. sipylea that had the least antioxidant capacity (IC₅₀: 20.75 μg/mL). In conclusion, these results confirm that GABA_Areceptor modulating food plants possess strong antioxidative activity.

Anahtar Kelimeler

Sideritis,Lavanta,Karanfil

References

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Details

Primary Language

English

Subjects

Agricultural Engineering

Journal Section

Research Article

Authors

Sümeyye Şahin ^*
0000-0002-9344-7690
Türkiye

Publication Date

December 20, 2019

Submission Date

August 6, 2019

Acceptance Date

December 13, 2019

Published in Issue

Year 2019 Volume: 8 Number: 2

DOI

https://doi.org/10.29278/azd.602839

IZ

https://izlik.org/JA48NX35FC

Cite

RIS / Bibtex

APA

Şahin, S. (2019). Antioxidative capacities of some GABAA receptor modulating food plants. Akademik Ziraat Dergisi, 8(2), 237-242. https://doi.org/10.29278/azd.602839