ISIRGAN OTU BİYOAKTİF BİLEŞENLERİ VE ANALİTİK YÖNTEMLERLE İNCELENMESİ

Year 2024, , 40 - 50, 30.04.2024

Ayça İdil Öztürk , Zafer Ömer Özdemir

https://doi.org/10.53445/batd.1309813

Abstract

Bu çalışmanın amacı Urtica dioica L. (Isırgan otu) bitkisinin biyoaktif bileşenlerinin terapötik endikasyonları, analiz edilmesi ve bu doğrultuda kullanılan analitik yöntemlerin incelenmesidir.

Keywords

Isırgan otu (Urtica dioica sp.), yaprak, kök, flavonoid, spektroskopi, spektrofotometri.

BIOACTIVE COMPONENTS OF STINGING NETTLE AND ITS DETERMINATION BY ANALYTICAL METHODS

Abstract

The aim of this study is to analyze the therapeutic indications of the bioactive components of the Stinging nettle (Urtica dioica L.) plant and to analyze the analytical methods used for this purpose.

Keywords

Stinging nettle (Urtica dioica sp.), leaf, root, flavonoid, spectroscopy, spectrophotometry.

References

• Ait, A., Said, H., Benmoussa, A., Sbai, I., Otmani, E. L. ve Derfoufi, S. (2015). Highlights on nutritional and therapeutic value of stinging nettle (Urtica Dioica). International Journal of Pharmacy and Pharmaceutical Sciences, 7(10),8-14.
• Asgarpanah, J. ve Mohajerani, R. (2012). Phytochemistry and pharmacologic properties of Urtica dioica L. Journal of Medicinal Plants Research, 6(46), 5714-5719. doi:10.5897/JMPR12.540
• Aydın, H. B. (2022). Aydın, H.B. Isırgan Otu (Urtica Dioica L.) Ekstraktının Gıda Kaynaklı Campylobacter jejuni Üzerine Antimikrobiyal Aktivitesinin İncelenmesi, İstanbul .
• Bhusal, K. K., Magar, S. K., Thapa, R., Lamsal, A., Bhandari, S., Maharjan, R., Shrestha, J. (2022). Nutritional and pharmacological importance of stinging nettle (Urtica dioica L.): A review. Heliyon. Elsevier Ltd. doi:10.1016/j.heliyon.2022.e09717
• Cesur, A. ve Soyer, Y. (2021). Determination of Antimicrobial Effect of The Aqueous Extract of Stinging Nettle (Urtica dioica) on Biofilm Formation of Salmonella Enterica Serovars. Gıda, 46(2), 324-338. doi:10.15237/gida.gd21016
• Çolak, S., Çömlekcioğlu, N., Aygan, A. (2020). Urtica dioica Bitki Özütlerinin Antioksidan ve Antimikrobiyal Aktivitelerinin İncelenmesi. Eurasian Journal of Biological and Chemical Sciences, 3(Suppl 1)), 206-212. doi:10.46239/ejbcs.730669
• Devkota, H. P., Paudel, K. R., Khanal, S., Baral, A., Panth, N., Adhikari-Devkota, A., Hansbro, P. M. (2022). Stinging Nettle (Urtica dioica L.): Nutritional Composition, Bioactive Compounds, and Food Functional Properties. Molecules. MDPI. doi:10.3390/molecules27165219
• Đurović, S., Micić, D., Šorgić, S., Popov, S., Gašić, U., Tosti, T., Zeković, Z. (2023). Recovery of Polyphenolic Compounds and Vitamins from the Stinging Nettle Leaves: Thermal and Behavior and Biological Activity of Obtained Extracts. Molecules, 28(5), 2278. doi:10.3390/molecules28052278
• Đurović, S., Pavlić, B., Šorgić, S., Popov, S., Savić, S., Pertonijević, M., Zeković, Z. (2017). Chemical composition of stinging nettle leaves obtained by different analytical approaches. Journal of Functional Foods, 32, 18-26. doi:10.1016/j.jff.2017.02.019
• Đurović, S., Pezo, L., Gašić, U., Gorjanović, S., Pastor, F., Bazarnova, J. G., Zeković, Z. (2023). Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction. Foods, 12(4). doi:10.3390/foods12040809
• Erarslan, Z. B., Ecevit Genc, G. ve Kultur, S. (2020). Medicinal plants traditionally used to treat skin diseases in Turkey – Eczema, psoriasis, vitiligo. Ankara Universitesi Eczacilik Fakultesi Dergisi. doi:10.33483/jfpau.586114
• Hürriyet Gazetesi. (2020).Hürriyet Gazetesi. 28 Mayıs 2023 tarihinde https://www.hurriyet.com.tr/lezizz/giresun-usulu-isirgan-corbasi-tarifi-41563851 adresinden erişildi.
• Jeszka-Skowron, M., Zgoła-Grześkowiak, A., Frankowski, R., Grześkowiak, T. ve Jeszka, A. M. (2022). Variation in the Content of Bioactive Compounds in Infusions Prepared from Different Parts of Wild Polish Stinging Nettle (Urtica Dioica L.). Molecules, 27(13). doi:10.3390/molecules27134242
• Karakaş, S. (2003). Isırgan Otu Toprak Altı Ve Toprak Üstü Kısımlarından Isırgan Otu Ekstraktının Eldesi ve Özelliklerinin İncelenmesi (İstanbul Teknik Üniversitesi Fen Bilimleri Enstitüsü).
• Karakuş S. A. ve Şen Ö. (2021). Jinekolojik Kanserlerde Kullanılan Tamamlayıcı ve Alternatif Tedavi Yöntemleri. Izmir Democracy University Health Sciences Journal. doi:10.52538/iduhes.874763
• Kavalalı, G. (2011a). Kavalalı, Gülsel. Lokman Hekim Journal (C. 1). http://lokmanhekim.mersin.edu.tr adresinden erişildi.
• Kavalalı, G. (2011b). Kavalalı, Gülsel. Lokman Hekim Journal (C. 1). http://lokmanhekim.mersin.edu.tr adresinden erişildi.
• Koraqi, H., Qazimi, B., Khalid, W., Stanoeva, J. P., Sehrish, A., Siddique, F., Zongo, E. (2023). Optimized conditions for extraction, quantification and detection of bioactive compound from Nettle (Urtica dioica L.) using the deep eutectic solvents, ultra-sonication and liquid chromatography-mass spectrometry (LC-DAD-ESI-MS/MS). International Journal of Food Properties, 26(1), 2171-2185. doi:10.1080/10942912.2023.2244194
• Otles, S. ve Yalcin, B. (2012). Phenolic compounds analysis of root, stalk, and leaves of nettle. The Scientific World Journal, 2012. doi:10.1100/2012/564367
• Hakan, Ö. Z. E. R., Çoban, F., Bouljak, M. S. (2020). Doğu Anadolu Bölgesinin Önemli Tıbbi-Aromatik Bitkileri. Erciyes Tarım ve Hayvan Bilimleri Dergisi, 3(1), 16-23.
• Paulauskienė, A., Tarasevičienė, Ž. ve Laukagalis, V. (2021). Influence of harvesting time on the chemical composition of wild stinging nettle (Urtica dioica l.). Plants, 10(4). doi:10.3390/plants10040686
• Rafajlovska, V., Djarmati, Z., Najdenova, V., Cvetkov, L. (2002). Extraction of stinging nettle (Urtica dioica L.) with supercritical carbondioxide. Balıkesir Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 4(2), 49-52.
• Petruzzello, M. (2024). Stinging nettle. Encyclopedia Britannica. https://www.britannica.com/plant/stinging-nettle
• Taheri, Y., Quispe, C., Herrera-Bravo, J., Sharifi-Rad, J., Ezzat, S. M., Merghany, R. M., Cho, W. C. (2022). Urtica dioica -Derived Phytochemicals for Pharmacological and Therapeutic Applications. Evidence-based Complementary and Alternative Medicine. doi:10.1155/2022/4024331
• Temiz, E., Koyuncu, İ., Saadat, S., Yüksekdağ, Ö. ve Award, Y. (2021). Exploring the Antiproliferative Mechanisms of Urtica dioica L. extract in Human Promyelocytic Leukemia Cell Line. Harran Üniversitesi Tıp Fakültesi Dergisi, 18(3), 468-474. doi:10.35440/hutfd.1012538
• Uzun Yaylacı, E. (2021). Antibacterial Effects of Boric Acid Against Aquatic Pathogens. Journal of Anatolian Environmental and Animal Sciences, 6(2), 240-244. doi:10.35229/jaes.881144
• Wetherilt, H. (1989). Isırgan Otu Yaprak ve Tohumların Besleyici Özellikleri ve Antitümörel Etkileri, İstanbul.
• Yalçın, B. (2011). Isırgan Otundaki (Urtica Dioica) Bazı Fenolik Bileşiklerin İncelenmesi, İzmir.