TAVUKLARDA CORONAVİRUS VE ENFEKSİYÖZ BRONŞİTİS AŞILARI

Yıl 2022, , 110 - 117, 15.06.2022

Özlem Kardoğan

https://doi.org/10.35864/evmd.1004464

Cited By: 1

Öz

: Enfeksiyöz bronşitis (IB), kanatlı hayvan endüstrisindeki özellikle genç ve yetişkin yumurtacı ve broyler tavukların, solunum ve ürogenital sistemlerinde lezyonlara yol açan bu nedenle karkas gelişimi ve yumurta kalitesinde düşmeye neden olan prevalansı yüksek ve önemli ekonomik kayıplardan sorumlu akut, yüksek derecede bulaşıcı viral bir enfeksiyondur. Enfeksiyöz Bronşitis ilk kez 1930 yılında Amerika Birleşik Devletlerinde tavuklarda akut solunum yolu hastalığı olarak tanımlanmış, 1936 yılında ise etkeni olan virus (IBV) izole edilmiştir. Ülkemizde de ilk kez 1978 yılında Ankara bölgesindeki taramalarda aşısız sürülerde yapılan serolojik çalışmalarda belirlenmiş, 1980’li yıllarda tavuk yetiştiriciliğindeki hızlı artışa paralel olarak ülke genelinde yayılmıştır. Kapsamlı aşılama olsa bile, ticari olarak IB salgınları kümes hayvanları üreticileri için önemli bir sorun olmaya devam etmektedir. Sürekli olarak yeni serotipler ve varyantlar ortaya çıkmakta, bu da kümes hayvanı üreticilerini ve hayvan sağlığı şirketlerini aşılama planlarını sürekli olarak değerlendirmeye ve yeni aşılar üretmeye zorlamaktadır.

Anahtar Kelimeler

Enfeksiyöz Bronşitis, Tavuk Coronavirus, Tavuk coronavirus aşıları, Spike

CORONAVIRUS AND INFECTIOUS BRONCHITIS VACCINES IN CHICKENS

Öz

: Enfectious bronchitis (IB) is an acute, highly contagious viral enfection that causes lesions in the respiratory and urogenital systems of the poultry industry, especially young and adult layers and broiler chickens, thus causing a decrease in carcass development and egg quality, and is responsible for significant economic losses. Enfectious Bronchitis was first defined as an acute respiratory disease in chickens in the United States in 1930, and the causative virus (IBV) was isolated in 1936. It was first determined in our country in 1978 in serological studies conducted in unvaccinated flocks in Ankara region, and it spread throughout the country in parallel with the rapid increase in chicken breeding in the 1980s. Commercially, IB outbreaks remain a major problem for poultry producers, even with extensive vaccination. New serotypes and variants are constantly appearing, forcing poultry producers and animal health companies to constantly evaluate vaccination plans and produce new vaccines.

Anahtar Kelimeler

Chicken, Infectious Bronchitis, Chicken coronavirus, Chicken coronavirus vaccines, Spike

Kaynakça

• KAYNAKLAR Aral EM. (2016). Türkiye'de İnfeksiyöz Bronşitis Viruslarının RT-PCR ile Saptanması ve Moleküler Karakterizasyonu. Ankara Üni. Sağ. Bil. Ens. Doktora Tezi.
• Armesto M, Evans S, Cavanagh D, Abu-Median AB, Keep S, Britton P. (2011). A recombinant avian infectious bronchitis virus expressing a heterologous spike gene belonging to the 4/91 serotype. PLoS One e24352.
• Aziz T. (2020) Avian infectious bronchitis virus: infection, evolution, and immunity https://www.thepoultrysite.com/articles/avian-infectious-bronchitis-virus-infection-evolution-and-immunity. Erişim:06.12.2020.
• Bande F, Arshad SS, Hair Bejo M, Moeini H, Omar AR. (2015). Progress and challenges toward the development of vaccines against avian infectious bronchitis. J. Immunol. Res. 1–12.
• Bentley K, Armesto M, Britton P. (2013). Infectious bronchitis virus as a vector for the expression of heterologous genes. PLoS One 8, e67875.
• Bijlenga G. (1960). Untersuchungen u ̈ ber dei Wirksamkeit eines lebenden Impfstoffes gegen die infektio ̈ se Bronchitis der Hu ̈ hner mit einem am bebru ̈ teten Hu ̈ hnerei adaptierten, dem Trinkwasser zugefu ̈gten, autochthonen Virus-Stamm (Investigations on the Activ-ity of a Living Vaccine Against Infectious Bronchitis of Chickens with an Embryonated Egg-Adapted Autogenous Virus Strain Applied in the Drinking Water). Doctor’s Thesis. Berne, Switzerland.
• Boltz DA, Nakai M and Bahra JM. (2004). Avian infectious bronchitis virus: A possible cause of reduced fertility in the rooster. Avian Dis., 48: 909-915.
• Britton P, Evans S, Dove B, Davies M, Casais R, Cavanagh D. (2005). Generation of a recombinant avian coronavirus infectious bronchitis virus using transient dominant selection. J. Virol. Methods 123,. 203–211.
• Callison SA, Hilt DA, Boynton TO, Sample BF, Robison R, Swayne DE, Jackwood MW. (2006). Development and evaluation of a real-time Taqman RT-PCR assay for the detection of infectious bronchitis virus from infected chickens. J. Virol. Methods 138, 60–65.
• Casais R, Dove B, Cavanagh, D, Britton P. (2003). Recombinant avian infectious bronchitis virus expressing a heterologous spike gene demonstrates that the spike protein is a determinant of cell tropism. J. Virol. 77, 9084–9089.
• Casais R, Davies M, Cavanagh D, Britton P. (2005). Gene 5 of the avian coronavirus infectious bronchitis virus is not essential for replication. J. Virol. 79, 8065– 8078.
• Cavanagh D, Davis DJ, Cook J, Li D, Kant A, and Koch G. (1992). Location of the amino acid differences in the Si spike glycoprotein subunit of closely related serotypes of infectious bronchitis virus. Avian Pathol. 21: 33-43.
• Cavanagh D, Elus MM, and Cook JK. (1997). The pathogenicity of new variant IBV isolates need sequence variation in the SI spike protein of infectious bronchitis virus and the extent of cross-protection in vivo. Avian Pathol. 26:63.
• Cavanagh D. (2001) A nomenclature for avian coronavirus isolates and the question of species status. Avian Pathol. 30, 109–115. Cavanagh D. (2003). Severe acute respirarory syndrome vaccine development: experience of vaccination against avian infec¬tious bronchitis coronovirus. Avian Pathol. 32(6), 567-582.
• Cavanagh D. (2005). Coronaviruses in poultry and other birds. Avian Pathol. 34, 439–448.
• Cavanagh D. (2007). Coronavirus avian infectious bronchitis virus. Vet. Res. 38, 281–297.
• Cavanagh D, Casais R, Armesto M, Hodgson T, Izadkhasti S, Davies M, Lin F, Tarpey I, Britton P. (2007). Manipulation of the infectious bronchitis coronavirus genome for vaccine development and analysis of the accessory proteins. Vaccine 25, 5558–5562.
• Cavanagh D, Gelb J. (2008). Infectious bronchitis. In Saif YM, Fadly AM, Glisson JR, McDougald LR, Nolan LK & Swayne DE. (Eds.). Diseases of Poultry 12th edn (pp. 117–135). Ames, Iowa, USA: Blackwell Publishing Professional.
• Cook JKA, Orbell SJ, Woods MA, Huggins MB.(1999). Breadth of protection of the respiratory tract provided by different live-attenuated infectioius bronchitis vaccines against challenge with infectious bronchitis viruses of heterologous serotypes. Avian Pathol. 28, 477–485.
• Cook J, Jackwood M. (2020). www.enfeksiyoz-bronsitis.com. Erişim Tarihi:27.11. 2020.
• Çelebi M. (2009). Yeni Bir İnfeksiyöz Bronşitis Virusu Olan 4/91 (793b)’in Ege Bölgesinde varlığının Ortaya Konulması. Doktora Tezi Adnan Menderes Üni. Sağ. Bil. Ens.
• Çöven F. (2012). Kanatlıların Enfeksiyöz Bronşitis Hastalığı Yumurta Bülteni. sayı:10;14-16.
• Darteil R, Bublot M, Laplace E, Bouquet JF, Audonnet JC, Rivière M. (1995). Herpesvirus of turkey recombinant viruses expressing infectious bursal disease virus (IBDV) VP2 immunogen induce protection against an IBDV virulent challenge in chickens. Virology 211, 481–490.
• de Wit JJ, Cook JK and Van Der Heıjden HM. (2011). Infectious bronchitis virus variants: a review of the history, current situation and control measures. Avian Pathol. 40, 223–235.
• Esendal MÖ. (2002). Enfeksiyöz Bronsitis, Kanatlı Hayvan Hastalıkları. Editörler: İzgür.M., Akan.M., Medisan Yayınları.50. Ankara, 155-162.
• Fang Y, Yujun Z, Yongting H, Jianyang Q, Wenxin L, Wenhui J, Xuying L, Qian W, Xiumin S, Zhong L. (2013). Protection of chickens against infectious bronchitis virus with a multivalent DNA vaccine and boosting with an inactivated vaccine. J. Vet. Sci. 14, 53–60.
• Goncagül G, Kardoğan Ö, Günaydın E. (2020). İç Anadolu'da enfeksiyöz bronşit virüsü aşılamasının etkinliği. Etlik Mikrobiyoloji Derg, cilt 31 sayı 2 syf 147-153.
• Gelb Jr, Rosenberger J, Fries JK, Cloud PA, Odor SS, Dohms EM, Jaeger JS. (1989). Protection afforded infectious bronchitis virus-vaccinated sentinel chickens raised in a commercial environment. Avian Dis. 33, 764–769.
• Guo Z, Wang H, Yang T, Wang X, Lu D, Li Y, Zhang Y. (2010). Priming with a DNA vaccine and boosting with an inactivated vaccine enhance the immune response against infectious bronchitis virus. J. Virol. Methods 167, 84–89.
• Hodgson T, Casais R, Dove B, Britton P, Cavanagh D. (2004). Recombinant infectious bronchitis coronavirus Beaudette with the spike protein gene of the pathogenic M41 strain remains attenuated but induces protective immunity. J. Virol. 78, 13804–13811.
• Hudu SA, Shinkafi SH, Umar S. (2016). An overview of recombinant vaccine technology, adjuvantts ant vaccine delivery method. International Journal of Pharmacy and Pharmaceutical Sciences. 8(11): 19-24.
• Jackwood MW. (2012). Review of Infectious Bronchitis Virus Around the World Avian Diseases. Vol. 56, No. 4 pp. 634-641.
• Jackwood MW, de Wit S. (2013). Infectious bronchitis. In: Swayne, D.E., Glisson, J.R., McDougald, L.R., Nolan, L.K., Suarez, D.L., Nair, V. (Eds.), Diseases of Poultry. Wiley-Blackwell Publishing, Ames, Iowa, Ames, IA,. pp. 139–160.
• Jackwood MW, Hilt DA, Sellers HS, Williams SM, Lasher HN. (2010). Rapid heat-treatment attenuation of infectious bronchitis virus. Avian Pathol.. 39, 227–233.
• Jackwood MW, Jordan BJ, Roh HJ, Hilt DA, Williams SM. (2015). Evaluating protection against infectious bronchitis virus by clinical signs, ciliostasis, challenge virus detection, and histopathology. Avian Dis.. 59, 368–374.
• Johnson MA, Pooley C, Ignjatovic J, Tyack SG. (2003). A recombinant fowl adenovirus expressing the S1 gene of infectious bronchitis virus protects against challenge with infectious bronchitis virus. Vaccine 21,. 2730–2736.
• Jordan BJ. (2016). Spray Application of Infectious Bronchitis Virus Vaccines in the Hatchery: How Efficient are We? XXIV Congreso de Avicultura Centroamericany del Caribe. http://www.anaviguatemala.org/xxiv-congreso-de-avicultura-centroamericano-y-del caribe/2016.
• Jordan BJ. (2017). Vaccination against infectious bronchitis virus: A continuous challenge. Veterinary Microbiology, 206. 137–143.
• Jungherr EI, Chomiak TW, Luginbuhl RE. (1956). Immunologic differences in strains of infectious bronchitis virus. Proc. 60th Annual Meeting U.S. Livestock Sanitary Association.. 203-209.
• Kahya S, Çöven F, Temelli S, Eyigör A, Çarlı KT. (2013). Presence of IS/1494/06 genotype-related infectious bronchitis virus in breeder and broiler flocks in Turkey. Ankara Üniv Vet Fak Derg. 60, 27-31.
• Ladman BS, Loupos AB, Gelb Jr. J. (2006). Infectious broncihitis virus SI gene sequence comparison is a better predictor of challenge of immunity in chickens than serotyping by virus neutralization. Avian Pathol. 35:127-133.
• Lee CW, Hilt DA, Jackwood MW. (2003). Typing of field isolates of infectious bronchitis virus based on the sequence of the hypervariable region in the SI gene. J. Vet. Diagn. Invest. 15:344-348.
• Li M, Wang XY, Wei P, Chen QY, Wei ZJ, Mo ML. (2011). Serotype and genotype diversity of infectious bronchitis viruses isolated during 1985—2008 in Guangxi, China. Arch. Virol. 57:467.
• Li H, Wang Y, Han Z, Wang Y, Liang S, Jiang L, Hu Y, Kong X, Liu S. (2016). Recombinant duck enteritis viruses expressing major structural proteins of the infectious bronchitis virus provide protection against infectious bronchitis in chickens. Antiviral Res. 130, 19–26.
• Morgan RW, Gelb Jr, Schreurs J, Lutticken CS, Rosenberger D, Sondermeijer PJ. (1992). Protection of chickens from Newcastle and Marek's diseases with a recombinant herpesvirus of turkeys vaccine expressing the Newcastle disease virus fusion protein. Avian Dis. 36, 858–870.
• OIE 2018. Manual of standards for diagnostic tests and vaccines. Office International des Epizooties, Chapter 3.3.2.World Organisation for Animal Health, Paris. Erişim tarihi:12.06.2021.
• Öngör H, Timurkaan N, Çöven F, Karabulut B, Eröksüz H, Çetinkaya B. (2021). Detection of Israel variant 2 (IS/1494/06) genotype of Infectious Bronchitis Virus in a layer chicken flock. Ankara Univ Vet Fak Derg, 68, 167-172, 2021 DOI: 10.33988/auvfd.756970.
• Pharmacopoeia. (2016). Avian Infectious Bronchitis Vaccine (live). European Pharmacopoeia, pp. 1008–1010.
• Purswell JL, Fritz BK, Branton SL, Leigh SA. (2008). Effects of system pressure and nozzle type on spray application of avian vaccines. Appl. Eng. Agric. 24,785–789.
• Rautenschlein S, Hans-Christian P (2021). Infectious bronchitis: 80 years of control efforts to combat a Coronavirus infection in poultry. Berliner und Münchener tierärztliche Wochenschrift Vol. 134, No.1 DOI:10.2376/1439-0299-2020-27.
• Roh HJ, Jordan BJ, Hilt DA, Jackwood MW. (2014). Detection of infectious bronchitis virus with the use of real-time quantitative reverse transcriptase- PCR and correlation with virus detection in embryonated eggs. Avian Dis. 58, 398–403.
• Roh HJ, Jordan BJ, Hilt DA, Ard MB, Jackwood MW. (2015). Hatchery spray cabinet administration does not damage avian coronavirus infectious bronchitis virus vaccine based on analysis by electron microscopy and virus titration. Avian Dis. 9, 149–152.
• Terregino C, Toffan A, Beato MS, Nardi RD, Vascellari M, Meini A, Ortali G, Mancin M, Capua I. (2008). Pathogenicity of a QX strain of infectious bronchitis virus in specific pathogen free and commercial broiler chickens, and evaluation of protection induced by a vaccination programme based on the Ma5 and 4/91 serotypes. Avian Pathol. 37, 487–493.
• Toro H, Zhang JF, Gallardo RA, van Santen VL, van Ginkel FW, Joiner KS, Breedlove C. (2014). S1 of distinct IBV population expressed from recombinant adenovirus confers protection against challenge. Avian Dis. 58, 211–215.
• Toro H, van Santen VL, Ghetas, AM, Joiner KS. (2015). Cross-protection by infectious bronchitis viruses under controlled experimental conditions. Avian Dis. 59, 532–536.
• USDA. 1999. Title 9, Code of Federal Regulations, Standard Requirements for IBV Vaccines. Animal and Plant Health Inspection Service, USDA Section 113 p.
• Vagnozzi A, Zavala G, Riblet SM, Mundt A, Garcia M. (2012). Protection induced by commercially available live-attenuated and recombinant viral vector vaccines against infectious laryngotracheitis virus in broiler chickens. Avian Pathol. 41, 21–31.
• Valastro V, Holmes EC, Britton P, Fusaro A, Jackwood MW, Cattoli G et al. (2016). S1 gene-based phylogeny of infectious bronchitis virus: An attempt to harmonize virus classification. Infection, Genetics and Evolution, 39, 349-364.
• Yılmaz H, Altan E, Çizmecigil UY, et al (2016). Phylogeny and S1 gene variation of infectious bronchitis virus detected in broilers and layers in Turkey. Avian Dis, 60, 596-602.
• Wang Y, Wang Y, Zhang Z, Fan G, Jiang Y, Liu Xiang E, Ding J, Wang S. (1998). Isolation and identification of glandular stomach type IBV (QX IBV) in chickens. Chin. J. Anim. Quar. 15, 1–3.
• Wang N, Shang J, Jiang J and Du L(2020). Subunit Vaccines Against Emerging Pathogenic Human Coronaviruses Front. Microbiol. doi.org/10.3389/fmicb.2020.00298.
• Wickramasinghe INA, van Beurden SJ, Weerts E, Verheije MH. (2014). The avian coronavirus spike protein. Virus Res. 194, 37–48. 142.