Araştırma Makalesi
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Etlik Piliçlerde Kullanılan Çeşitli Veteriner İlaçlarının Kalıntıları Üzerine Pişirme, Dondurma ve Benzeri İşlemlerinin Etkilerinin Araştırılması -Kinolon Grubu Bazı Antibakteriyellerin incelenmesi

Yıl 2002, Cilt: 13 Sayı: 1, 56 - 76, 01.06.2002

Öz

Bu araştırma, hayvan hastalıklarının tedavisinde sıklıkla kullanılan sulfonamid grubu
ilaçlardan sulfadimetoksin, sulfakinoksalin ve sulfadoksinin etlik piliçlerin göğüs, but ve
karaciğer dokularındaki kalıntıları üzerine çeşitli pişirme işlemlerinin (ızgara, tuzlu ve tuzsuz
haşlama)ve derin dondurucuda (-1 8°C) farklı sürelerde bekletmenin etkilerini belirlemek
amacıyla yapılmıştır.
Yapılan analizler sonucunda farklı pişirme işlemlerinin sulfadimetoksin, sulfakinoksalin
ve sulfadoksin kalıntıları üzerinde belirgin bir azalmaya neden olduğu, derin dondurucuda
farklı sürelerde bekletmede ise sülfadoksin için sadece but dokusunda, sülfakinoksalin için ise
sadece göğüs dokusunda 20 günlük saklama ile istatistikse~ olarak önemli bir azalma (p<0.05)
bulunmuştur.

Kaynakça

  • ASCALONE V (1980). Assay of trimethoprim, sulfamethoxazole and its N4-acetyl metabolile in biological fluids by high-pressure liquid chromatography. High Resolution Chromatogr Commun, 3:261-264.
  • BAYDAN E (1996). Türkiye'de veteriner ilaçlarımn dünü ve bugünü. Türk Vet Hek Derg, 8: 4-5.
  • BEVILL RF (1984). Factors influencing the occurrence of drug residues in animal tissues after the use of antimicrobial agents in animal feeds. JAVMA, ı 85: ı ı24- I 126.
  • BOlSON JO ET AL (1992). Effect ofcoldtenıperature storage on stability of benzylpenicillin residues in plasma and tissues of food-producing animals. JAOAC International, 75: 974-978.
  • EPSTEIN RL ET AL (ı 988). lnfluence of heat and cure preservatives on residues of sulfamethazine, chloramphenicol, and cyromazine in muscle tissue. J Agric Food Chem, 36:1009-0ı2.
  • HASSETT T ET AL (1990). The effect of cooking on drug residues in nıeat and offal. EuroResidue Conference on Residues of Veterinary Oru gs in Food, pp.2 I I -2 ı 5.
  • INGLlS JM AND KATZ SE (ı978). Determination of streptomycin residues in eggs and stability of residues after cooking J Ass oc Off Anal C hem, 6 ı: ı 098-1102.
  • KATZ SE AND LEVINE PR (1978). Determination of neomycin residues in eggs and stability of residues after cooking J Assoc Off Anal Ch em, 61: 1 ı 03-1106.
  • KAYA S (2000). Kemoterapötikler. İçinde: Veteriner Uygulamalı Farmakoıoji (Eds.S. Kaya, i. Pirinçci, A. Bilgili) Cilt2, Baskı2. Medisan Yayınevi. Seri 42, Ankara.
  • Kaya S VE ARK (1992). Mezbahadan sağlanan Siğır et, karaciğer ve böbrek örneklerinde antibiyotik kalıntıları. AÜ Vet Fak Derg, 39:13-29.
  • LASHEV LD AND MIHAILOV R (1994).Pharmacokinetics ofsulphamethaxazole and tremethoprim administered intravenously and orally to japanese quails. J Vet Pharmacol Ther, 17:327-30.
  • LI T, QIAO GL, HU GZ, MENG FD, QIU YS, ZHANG XY, GUO WX, YlE HL, LI SF AND LI SY ( 1995). Comparative plasma and tissue pharmacokinetics and drug residue profi/es of different chemotherapeutants in fowls and rabbits. J Vet Phar:macol Ther, 18: 260-73.
  • LOSCHER W, FASSEENDER CP, WEISSING M AND KIETZMANN M ( 1990). Drug plasma !eve/s fallawing admin~ istration of trimethoprim and sulphonamide combinations to broilers. J Vet Pharmacol Ther, 13: 309-ı9.
  • NOUWS JFM (1981). Tolerances and · detection of antimicrobial residues in slaughtered animals. Are für Lebensmitteıhygi, 32: 92-ı40.
  • NOUWS JFM AND ZIV G (ı976). The effect ofstorage at 4°C on antibiotic residues in kidney and meat tissues of dairy cows. Tijdschr Diergeneesk, ıoı: ıı45.
  • O'BRIEN JJ ET AL (1980). Antibiotic residues in meat: cooking and cold storage effects. Vet Re c, 106: 365.
  • ÖZKAZANÇ N VE KAYA S (1983). Hayvanların pişmemiş yenilebilir dokularında sulfonamid analizi. Ankara Üniv Vet Fak Derg, 30: 624-638 . .
  • ROSE MD ET AL (1995). The effect of cooking on veterinGJ·y drug residues in food: Clenbuterol. Food Add Contamin, 12: 67- 76.
  • ROSE MD ET AL (ı 995). The effect of cooking on veterinary drug residues in food : Levamisole. Food Add Contamin, 12: 185-ı94 .
  • WAGNER lG (1975). Fundamentals of Clinical Pharmacokineties. Ist Ed. Drug Intelligence Publications, Ine., Hamilton, lllionis.

THE EFFECTS OF COOKING, FREEZlNG AND SOME SIMILAR PROCESSES ON THE VETERINARY DRUG RESIDUES IN BROILER TISSUES- Research of some antibacterials group of quinolone

Yıl 2002, Cilt: 13 Sayı: 1, 56 - 76, 01.06.2002

Öz

This study was performed to determine effect of different cooking processed and different
stocking time at -1 8°C on sulfadimethoxine, sulfaquinoxaline, and sulfadoxine residues in
broiler tissues.
The tissues have been processed by grilling and boiling in water with salt and without
salt (both tissue and its gravy). After cooking processed sulfadimethoxine, sulfaquinoxaline
and sulfadoxine levels in tissue were measured (as ppm). The results of analysis indicated that
the sulfadimethoxine, sulfaquinoxaline and sulfadoxine residues of in the poultry tissues significantly
decreased after the different cooking procedures. But sulfadimethoxine,- sulfaquinoxaline
and sulfadoxine residues of in the poultry tissues didn't decrease different stocking
time at -1 8°C

Kaynakça

  • ASCALONE V (1980). Assay of trimethoprim, sulfamethoxazole and its N4-acetyl metabolile in biological fluids by high-pressure liquid chromatography. High Resolution Chromatogr Commun, 3:261-264.
  • BAYDAN E (1996). Türkiye'de veteriner ilaçlarımn dünü ve bugünü. Türk Vet Hek Derg, 8: 4-5.
  • BEVILL RF (1984). Factors influencing the occurrence of drug residues in animal tissues after the use of antimicrobial agents in animal feeds. JAVMA, ı 85: ı ı24- I 126.
  • BOlSON JO ET AL (1992). Effect ofcoldtenıperature storage on stability of benzylpenicillin residues in plasma and tissues of food-producing animals. JAOAC International, 75: 974-978.
  • EPSTEIN RL ET AL (ı 988). lnfluence of heat and cure preservatives on residues of sulfamethazine, chloramphenicol, and cyromazine in muscle tissue. J Agric Food Chem, 36:1009-0ı2.
  • HASSETT T ET AL (1990). The effect of cooking on drug residues in nıeat and offal. EuroResidue Conference on Residues of Veterinary Oru gs in Food, pp.2 I I -2 ı 5.
  • INGLlS JM AND KATZ SE (ı978). Determination of streptomycin residues in eggs and stability of residues after cooking J Ass oc Off Anal C hem, 6 ı: ı 098-1102.
  • KATZ SE AND LEVINE PR (1978). Determination of neomycin residues in eggs and stability of residues after cooking J Assoc Off Anal Ch em, 61: 1 ı 03-1106.
  • KAYA S (2000). Kemoterapötikler. İçinde: Veteriner Uygulamalı Farmakoıoji (Eds.S. Kaya, i. Pirinçci, A. Bilgili) Cilt2, Baskı2. Medisan Yayınevi. Seri 42, Ankara.
  • Kaya S VE ARK (1992). Mezbahadan sağlanan Siğır et, karaciğer ve böbrek örneklerinde antibiyotik kalıntıları. AÜ Vet Fak Derg, 39:13-29.
  • LASHEV LD AND MIHAILOV R (1994).Pharmacokinetics ofsulphamethaxazole and tremethoprim administered intravenously and orally to japanese quails. J Vet Pharmacol Ther, 17:327-30.
  • LI T, QIAO GL, HU GZ, MENG FD, QIU YS, ZHANG XY, GUO WX, YlE HL, LI SF AND LI SY ( 1995). Comparative plasma and tissue pharmacokinetics and drug residue profi/es of different chemotherapeutants in fowls and rabbits. J Vet Phar:macol Ther, 18: 260-73.
  • LOSCHER W, FASSEENDER CP, WEISSING M AND KIETZMANN M ( 1990). Drug plasma !eve/s fallawing admin~ istration of trimethoprim and sulphonamide combinations to broilers. J Vet Pharmacol Ther, 13: 309-ı9.
  • NOUWS JFM (1981). Tolerances and · detection of antimicrobial residues in slaughtered animals. Are für Lebensmitteıhygi, 32: 92-ı40.
  • NOUWS JFM AND ZIV G (ı976). The effect ofstorage at 4°C on antibiotic residues in kidney and meat tissues of dairy cows. Tijdschr Diergeneesk, ıoı: ıı45.
  • O'BRIEN JJ ET AL (1980). Antibiotic residues in meat: cooking and cold storage effects. Vet Re c, 106: 365.
  • ÖZKAZANÇ N VE KAYA S (1983). Hayvanların pişmemiş yenilebilir dokularında sulfonamid analizi. Ankara Üniv Vet Fak Derg, 30: 624-638 . .
  • ROSE MD ET AL (1995). The effect of cooking on veterinGJ·y drug residues in food: Clenbuterol. Food Add Contamin, 12: 67- 76.
  • ROSE MD ET AL (ı 995). The effect of cooking on veterinary drug residues in food : Levamisole. Food Add Contamin, 12: 185-ı94 .
  • WAGNER lG (1975). Fundamentals of Clinical Pharmacokineties. Ist Ed. Drug Intelligence Publications, Ine., Hamilton, lllionis.
Toplam 20 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Veteriner Cerrahi
Bölüm Araştırma Makaleleri
Yazarlar

Emine Baydan Bu kişi benim

Rauf Akkaya Bu kişi benim

Bünyamin Traş Bu kişi benim

Ali Bilgili Bu kişi benim

Saadettin Tanyıldızı Bu kişi benim

Ayhan Filazi Bu kişi benim

Ender Yarsan Bu kişi benim

Mehmet Özdemir Bu kişi benim

Yayımlanma Tarihi 1 Haziran 2002
Gönderilme Tarihi 1 Ocak 2002
Yayımlandığı Sayı Yıl 2002 Cilt: 13 Sayı: 1

Kaynak Göster

APA Baydan, E., Akkaya, R., Traş, B., Bilgili, A., vd. (2002). Etlik Piliçlerde Kullanılan Çeşitli Veteriner İlaçlarının Kalıntıları Üzerine Pişirme, Dondurma ve Benzeri İşlemlerinin Etkilerinin Araştırılması -Kinolon Grubu Bazı Antibakteriyellerin incelenmesi. Etlik Veteriner Mikrobiyoloji Dergisi, 13(1), 56-76.


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