C VİTAMİNİNİN 2-KETO-L-GULONİK ASİT MOLEKÜLÜNDEN ÜRETİMİ İÇİN FARKLI METOTLARIN ARAŞTIRILMASI

Year 2023, , 394 - 404, 15.04.2023

Ceren Mutlu , Cihadiye Candal Uslu , Mustafa Erbas

https://doi.org/10.15237/gida.GD22126

Abstract

Araştırmada farklı metotlar kullanılarak 2-keto-L-gulonik asit molekülünün esterifikasyonu ve laktonizasyonu ile ülkemizde ilk defa C vitamini üretiminin gerçekleştirilmesi amaçlanmıştır. Bu amaç doğrultusunda C vitamininin üretimi için dört metot, C vitamininin sodyum tuzunun üretimi için dört metot ve C vitamininin potasyum tuzunun üretimi için ise bir metot olmak üzere toplamda dokuz farklı metot kullanılarak denemeler yapılmıştır. Elde edilen bulgulara göre; doğrudan C vitamini üretimi için %36.07 verim ile Metot-I’in, C vitamininin sodyum tuzu üretimi için %58.56 verim ile Metot-VIII’in ve C vitamininin potasyum tuzu üretimi için ise %28.22 verim ile Metot-IX’un kullanılabileceği değerlendirilmiştir.

Keywords

2-keto-L-gulonik asit, askorbik asit, esterifikasyon, lakton

Supporting Institution

TÜBİTAK

Project Number

118O859

Thanks

Projeye (1005-Ulusal Yeni Fikirler ve Ürünler Araştırma Destek Programı-Proje No: 118O859) verdikleri destek nedeniyle Türkiye Bilimsel ve Teknolojik Araştırma Kurumu’na (TÜBİTAK) teşekkür ederiz.

INVESTIGATION OF DIFFERENT METHODS FOR PRODUCTION OF VITAMIN C FROM 2-KETO-L-GULONIC ACID MOLECULE

Abstract

In the study, it was aimed to produce vitamin C for the first time in our country by esterification and lactonization of 2-keto-L-gulonic acid molecule using different methods. For this purpose, experiments were carried out using a total of nine different methods as four methods to produce vitamin C, four methods to produce the sodium salt of vitamin C, and one method to produce the potassium salt of vitamin C. According to the obtained results, it was evaluated that Method-I with a yield of 36.07% for the direct production of vitamin C, Method-VIII with a yield of 58.56% for the production of vitamin C sodium salt, and Method-IX with a yield of 28.22% for the production of vitamin C potassium salt could be used.

Keywords

2-keto-L-gulonic acid, ascorbic acid, esterification, lacton

Project Number

118O859

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