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GIDALARDA BİYOJENAMİNLERLE İLGİLİ YASAL DÜZENLEMELER

Yıl 2012, Sayı: 12, - , 08.08.2014

Öz

Biyojen aminler amino asitlerin mikrobiyal dekarboksilasyonu ile veya aldehitlerin amino asit transaminaz enzimi ile deaminasyonu ile oluşmaktadırlar. Histamin, tiramin, putresin, kadaverin, triptamin, 2-feniletilamin, spermin, spermidin, agmatin, etilamin ve etanolamin gıdalarda oluşan başlıca biyojen aminlerdir.Yapılan çalışmalarda scombroid balık, peynir, sucuk, sauerkraut (susuz lahana turşusu), şarap ve birada yüksek düzeylerde biyojen amin tespit edilmiştir. Yüksek düzeyde biyojen amin içeren gıda tüketiminin başağrısı, mide bulantısı, kalp rahatsızlıkları, sindirim sorunlarına yol açtığı bilinmektedir.İnsanlarda biyojen aminlerin neden olduğu intoksikasyon düzeyini belirlemek oldukça güçtür. Çünkü bu durum kişilerin duyarlılığına ve diğer aminlerin varlığına bağlıdır. Öğün başına 40 mg biyojen amin alımı potansiyel toksik olarak rapor edilmiştir. Tüm biyojen aminler aynı toksik etkiye sahip olmadıklarından histamin, tiramin ve 2-feniletilamin düşünülerek bu genelleme yapılmıştır. Bu nedenle ABD, İsveç, Avusturya ve Hollanda gibi ülkeler çeşitli gıdalarda biyojen aminler özellikle histamin için maksimum limit değerlerini içeren düzenlemeler yapmıştır. Türkiye'de konuyla ilgili sadece bir adet yasal düzenleme olup bu da balıkta histamin içindir. Bu çalışmanın amacı gıdalarda biyojen aminlerle ilgili yasal düzenlemelerin
bir derlemesini gerçekleştirmektir.


Anahtar Kelimeler: Biyojen amin, gıda, histamin, tiramin, 2-feniletilamin

Kaynakça

  • Alberto, M. R., Arena, M. E., Narda, M. M. 2002. A comparative survey of two analytical methods for identificationand
  • quantification of biogenic amines. Food Control, 13(2):125-129. Anlı,R.E.,Vural,N.,Yılmaz, S.,Vural,Y.H., 2004.
  • The determination of biogenic amines inTurkish redwines.Journal of FoodComposition andAnalysis, 17?53-62
  • Anonim, 2008. Su ürünleri yönetmeliği, No: 2008/27004, Ek-9, Türkiye Cumhuriyeti, Tarım ve Köyişleri Bakanlığı,
  • Koruma veKontrolGenelMüdürlüğü.Askar,A.,Treptow,H., 1986.
  • BiogeneAmine inLebensmitteinVorkommen,Bedeutung undBestimmung,Eugen
  • UlmerGmbHand Co. Stuggart,Germany.Aygün, O., Schneider, E., Scheuer, R., Usleber, E., Gareis, M., Martlbauer, M.,
  • Comparison of Elisa and HPLC for the determination of histamine in cheese. Journal of Agricultural and Food
  • Chemistry, 47: 1961-1964.
  • Ayhan, K., Kolsarici, N., Ozkan, G. A., 1999. The effects of a starter culture on the formation of biogenic amines in
  • Turkish Soudjoucks. Meat Science, 5:183–188.
  • Azim, Ö., 2002. Gıdalarda Yüksek Basınç Sıvı Kromatografisi (HPLC) ile Biyojen Amin Analizleri, Yüksek Lisans
  • Tezi, Ege Üniversitesi Fen Bilimleri Enstitüsü, 89 s.
  • Bardocz, S., 1995. Polyamines in food and their consequences for food quality and human health. Trends in Food
  • Science andTechnology, 6:341–346.
  • Bjeldanes, L. F., Schutz, D. E., Morris, M. M., 1978. On the aetiology of scombroid poisoning: cadaverine potentiation
  • of histamine toxicity in the guinea-pig. Food and CosmeticsToxicology, 16:157–159.
  • Chang, S. F., Ayres, J. W., Sandine, W. E., 1985. Analysis of cheese for histamine, tyramine, tryptamine, histidine,
  • tyrosine and tryptophan. Journal of Dairy Science, 68:2840-2846.
  • Chiacchierini, E., Restuccia, D., Vinci, G., 2006. Evaluation of two different extraction methods for chromatographic
  • determination of bioactive amines in tomato products. Talanta, 69:548-555.
  • Custodio, F. B., Tavares, E., Gloria, M. B. A., 2007. Extraction of bioactive amines from grated parmesan cheese using
  • acid, alkaline and organic solvents, Journal of Food Composition and Analysis, 20: 280-288.
  • Eerola, S., Sagues, A. X. R., Lilleberg, L., Aalto, H., 1997. Biogenic amines in dry sausages during shelf-life storage.
  • Zeitung Lebensmittel For Untersuchung und ForschungA, 205:351–355.
  • Emborg, J., Dalgaard, P., 2006. Formation of histamine and biogenic amines in cold-smoked tuna: an investigation of
  • psychrotolerant bacteria from samples implicated in cases of histamine fish poisoning. Journal of Food Protection,
  • :897–906.
  • st Food and Drug Administration (FDA), 1996. Fish & fisheries products hazards & controls guide (1 ed.)Washington,
  • DC: FDA, Center for Food Safety andAppliedNutrition, Office of Seafood.
  • Gloria, M. B. A., Watson, B. T., Simon-Sarkadi, L., Daeschel, M. A., 1998. A survey of biogenic amines in Oregon
  • PinotNoir and Cabernet SauvignonWines.American Journal of Enology andViticulture, 49 (3):279-282.
  • Gonzaga, V. E., Lescano, A. G., Huaman, A. A., Salmn-Mulanovich, G., Blazes, D. L., 2009. Histamine levels in fish
  • from markets in Lima, Peru. Journal of Food Protection, 72:1112–1117.
  • Halasz, A., Barath, A., Simon-Sarkadi, L., Holzapfel, W., 1994. Biogenic amines and their production by
  • microorganisms in food.Trends in Food Science andTechnology, 5:42-49.
  • Hernandez-Jover, T., Izquierdo-Pulido, M., Veciana-Nogues, M.T., Marine-Font, A., Vidal-Carou, M. C., 1997.
  • Biogenic amines and polyamine contents in meat and meat products. Journal of Agricultural and Food
  • Chemistry,45:2098–2102.
  • Hornero-Mendez, D., Garrido-Fernandez, A., 1997. Rapid high performance liquid chromatography analysis of
  • biogenic amines in fermented vegetable brines. Journal of Food Protection, 60(4):414-419.
  • Ö. Özdestan ve A. Üren / Gıda ve Yem Bilimi - Teknolojisi Dergisi / Journal of Food and Feed Science - Technology 12:37-40 (2012)
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  • Künsch, U., Scharer, H., Pulver, D., Temperli, A., 1989. Formation of biogenic amines during sauerkraut fermentation.
  • International Conference Biotechnology and Food, Stuttgart.
  • Landete, J. M., Ferrer, S., Pardo, I., 2007. Biogenic amine production by lactic acid bacteria, acetic acid bacteria and
  • yeast isolated from wine. Food Control, 18 (12):1569-1574.
  • Lange, J., Wittmann, C., 2002. Enzyme sensor array for the determination of biogenic amines in food samples.
  • Analytical and Bioanalytical Chemistry, 372 (2):276-283.
  • Lange, J., Thomas, K., Wittmann, C., 2002. Comparison of a capillary electrophoresis method with high-performance
  • liquid chromatography for the determination of biogenic amines in various food samples. Journal of Chromatography
  • B, 779:229-239.
  • Latorre-Moratalla, M. L., Bover-Cid, S., Talon, R., Garriga, M., Zanardi, E., Ianieri, A., ve ark., 2010. Strategies to
  • reduce biogenic amine accumulation in traditional sausage manufacturing. LWT-Food Science andTechnology, 43:20-
  • -
  • Lehtonen, P., 1996. Determination of amines and amino acids in wine. American Journal of Enology and Viticulture,
  • :127-133.
  • Lonvaud-Funel, A., 2001. Biogenic Amines in wines: Role of lactic acid bacteria. FEMS Microbiology Letters, 199:9-
  • -
  • Mafra, I., Herbert, P., Santos, L., Barros, P., Alves, A., 1999. Evaluation of biogenic amines in some Portuguese quality
  • wines by HPLC fluorescence detection of OPA derivatives. American Journal of Enology and Viticulture, 50 (1):128-
  • -
  • Maijala, R., Eerola, S., 1993. Contaminant lactic acid bacteria of dry sausages produce histamine and tyramine. Meat
  • Science, 35(3):387-395.
  • Martinez-Villaluenga, C., Frıasa, J., Gulewicz, P., Gulewicz, K., Vidal-Valverde, C., 2008. Food safety evaluation of
  • broccoli and radish sprouts. Food and ChemicalToxicology, 46:1635-1644.
  • McCabe-Sellers, B. J., Staggs, C. G., Bogle, M. L., 2006. Tyramine in foods and monoamine oxidase inhibitor drugs: a
  • crossroad where medicine, nutrition, pharmacy, and food industry converge. Journal of Food Composition and
  • Analysis, 19:58–65.
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  • emerging approaches. Journal of Food Science, 75(7):139-150.
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  • *Bu makalenin bir kısmıNAFI 2011 Uluslararası Gıda Kongresinde poster bildiri olarak sunulmuştur.
Yıl 2012, Sayı: 12, - , 08.08.2014

Öz

Kaynakça

  • Alberto, M. R., Arena, M. E., Narda, M. M. 2002. A comparative survey of two analytical methods for identificationand
  • quantification of biogenic amines. Food Control, 13(2):125-129. Anlı,R.E.,Vural,N.,Yılmaz, S.,Vural,Y.H., 2004.
  • The determination of biogenic amines inTurkish redwines.Journal of FoodComposition andAnalysis, 17?53-62
  • Anonim, 2008. Su ürünleri yönetmeliği, No: 2008/27004, Ek-9, Türkiye Cumhuriyeti, Tarım ve Köyişleri Bakanlığı,
  • Koruma veKontrolGenelMüdürlüğü.Askar,A.,Treptow,H., 1986.
  • BiogeneAmine inLebensmitteinVorkommen,Bedeutung undBestimmung,Eugen
  • UlmerGmbHand Co. Stuggart,Germany.Aygün, O., Schneider, E., Scheuer, R., Usleber, E., Gareis, M., Martlbauer, M.,
  • Comparison of Elisa and HPLC for the determination of histamine in cheese. Journal of Agricultural and Food
  • Chemistry, 47: 1961-1964.
  • Ayhan, K., Kolsarici, N., Ozkan, G. A., 1999. The effects of a starter culture on the formation of biogenic amines in
  • Turkish Soudjoucks. Meat Science, 5:183–188.
  • Azim, Ö., 2002. Gıdalarda Yüksek Basınç Sıvı Kromatografisi (HPLC) ile Biyojen Amin Analizleri, Yüksek Lisans
  • Tezi, Ege Üniversitesi Fen Bilimleri Enstitüsü, 89 s.
  • Bardocz, S., 1995. Polyamines in food and their consequences for food quality and human health. Trends in Food
  • Science andTechnology, 6:341–346.
  • Bjeldanes, L. F., Schutz, D. E., Morris, M. M., 1978. On the aetiology of scombroid poisoning: cadaverine potentiation
  • of histamine toxicity in the guinea-pig. Food and CosmeticsToxicology, 16:157–159.
  • Chang, S. F., Ayres, J. W., Sandine, W. E., 1985. Analysis of cheese for histamine, tyramine, tryptamine, histidine,
  • tyrosine and tryptophan. Journal of Dairy Science, 68:2840-2846.
  • Chiacchierini, E., Restuccia, D., Vinci, G., 2006. Evaluation of two different extraction methods for chromatographic
  • determination of bioactive amines in tomato products. Talanta, 69:548-555.
  • Custodio, F. B., Tavares, E., Gloria, M. B. A., 2007. Extraction of bioactive amines from grated parmesan cheese using
  • acid, alkaline and organic solvents, Journal of Food Composition and Analysis, 20: 280-288.
  • Eerola, S., Sagues, A. X. R., Lilleberg, L., Aalto, H., 1997. Biogenic amines in dry sausages during shelf-life storage.
  • Zeitung Lebensmittel For Untersuchung und ForschungA, 205:351–355.
  • Emborg, J., Dalgaard, P., 2006. Formation of histamine and biogenic amines in cold-smoked tuna: an investigation of
  • psychrotolerant bacteria from samples implicated in cases of histamine fish poisoning. Journal of Food Protection,
  • :897–906.
  • st Food and Drug Administration (FDA), 1996. Fish & fisheries products hazards & controls guide (1 ed.)Washington,
  • DC: FDA, Center for Food Safety andAppliedNutrition, Office of Seafood.
  • Gloria, M. B. A., Watson, B. T., Simon-Sarkadi, L., Daeschel, M. A., 1998. A survey of biogenic amines in Oregon
  • PinotNoir and Cabernet SauvignonWines.American Journal of Enology andViticulture, 49 (3):279-282.
  • Gonzaga, V. E., Lescano, A. G., Huaman, A. A., Salmn-Mulanovich, G., Blazes, D. L., 2009. Histamine levels in fish
  • from markets in Lima, Peru. Journal of Food Protection, 72:1112–1117.
  • Halasz, A., Barath, A., Simon-Sarkadi, L., Holzapfel, W., 1994. Biogenic amines and their production by
  • microorganisms in food.Trends in Food Science andTechnology, 5:42-49.
  • Hernandez-Jover, T., Izquierdo-Pulido, M., Veciana-Nogues, M.T., Marine-Font, A., Vidal-Carou, M. C., 1997.
  • Biogenic amines and polyamine contents in meat and meat products. Journal of Agricultural and Food
  • Chemistry,45:2098–2102.
  • Hornero-Mendez, D., Garrido-Fernandez, A., 1997. Rapid high performance liquid chromatography analysis of
  • biogenic amines in fermented vegetable brines. Journal of Food Protection, 60(4):414-419.
  • Ö. Özdestan ve A. Üren / Gıda ve Yem Bilimi - Teknolojisi Dergisi / Journal of Food and Feed Science - Technology 12:37-40 (2012)
  • Ö. Özdestan ve A. Üren / Gıda ve Yem Bilimi - Teknolojisi Dergisi / Journal of Food and Feed Science - Technology 12:38-40 (2012)
  • Künsch, U., Scharer, H., Pulver, D., Temperli, A., 1989. Formation of biogenic amines during sauerkraut fermentation.
  • International Conference Biotechnology and Food, Stuttgart.
  • Landete, J. M., Ferrer, S., Pardo, I., 2007. Biogenic amine production by lactic acid bacteria, acetic acid bacteria and
  • yeast isolated from wine. Food Control, 18 (12):1569-1574.
  • Lange, J., Wittmann, C., 2002. Enzyme sensor array for the determination of biogenic amines in food samples.
  • Analytical and Bioanalytical Chemistry, 372 (2):276-283.
  • Lange, J., Thomas, K., Wittmann, C., 2002. Comparison of a capillary electrophoresis method with high-performance
  • liquid chromatography for the determination of biogenic amines in various food samples. Journal of Chromatography
  • B, 779:229-239.
  • Latorre-Moratalla, M. L., Bover-Cid, S., Talon, R., Garriga, M., Zanardi, E., Ianieri, A., ve ark., 2010. Strategies to
  • reduce biogenic amine accumulation in traditional sausage manufacturing. LWT-Food Science andTechnology, 43:20-
  • -
  • Lehtonen, P., 1996. Determination of amines and amino acids in wine. American Journal of Enology and Viticulture,
  • :127-133.
  • Lonvaud-Funel, A., 2001. Biogenic Amines in wines: Role of lactic acid bacteria. FEMS Microbiology Letters, 199:9-
  • -
  • Mafra, I., Herbert, P., Santos, L., Barros, P., Alves, A., 1999. Evaluation of biogenic amines in some Portuguese quality
  • wines by HPLC fluorescence detection of OPA derivatives. American Journal of Enology and Viticulture, 50 (1):128-
  • -
  • Maijala, R., Eerola, S., 1993. Contaminant lactic acid bacteria of dry sausages produce histamine and tyramine. Meat
  • Science, 35(3):387-395.
  • Martinez-Villaluenga, C., Frıasa, J., Gulewicz, P., Gulewicz, K., Vidal-Valverde, C., 2008. Food safety evaluation of
  • broccoli and radish sprouts. Food and ChemicalToxicology, 46:1635-1644.
  • McCabe-Sellers, B. J., Staggs, C. G., Bogle, M. L., 2006. Tyramine in foods and monoamine oxidase inhibitor drugs: a
  • crossroad where medicine, nutrition, pharmacy, and food industry converge. Journal of Food Composition and
  • Analysis, 19:58–65.
  • Naila, A., Flint, S., Fletcher, G., Bremer, P., Meerdink, G., 2010. Control of biogenic amines in food-existing, and
  • emerging approaches. Journal of Food Science, 75(7):139-150.
  • Nizamlıoğlu, M., 1990. Kaşar ve tulum peynirlerinde histamin ve tiramin düzeyleri. Doktora Tezi, Selçuk Üniversitesi
  • Sağlık Bilimleri Enstitüsü, Konya.
  • Nout, M. J. R., 1994. Fermented foods and food safety. Food Research International, 27(3): 291–298.
  • Ordonez, A. I., Ibanez, F. C., Torre, P., Barcina, Y., 1997. Formation of biogenic amines in Idiazabal Ewe's-milkcheese:
  • Effect of ripening, pasteurization and starter. Journal of Food Protection, 60 (11):1371-1375.
  • Önal, A., 2007. Current analytical methods for the determination of biogenic amines in foods. Food Chemistry,
  • : 1475-1486. Özdestan, Ö., Üren, A., 2006. Biyojen amin analiz yöntemleri. Akademik Gıda, 4(20):19-24.
  • Özdestan, Ö., Üren, A., 2009. A method for benzoyl chloride derivatization of biogenic amines for high performace
  • liquid chromatography. Talanta, 78:1321-1326.
  • Özdestan, Ö.,Alpözen, E., Güven, G., Üren,A., 2012. Monitoring of biogenic amines in kumru:Atraditional fermented
  • cereal food. International Journal of Food Properties, in press, DOI: 10.1080/10942912.2010.511754.
  • Özdestan, Ö., Üren, A., 2010. Biogenic amine content of kefir: A fermented dairy product. European Food Research
  • and Technology, 231 (1), 101-107.
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  • Ö. Özdestan ve A. Üren / Gıda ve Yem Bilimi - Teknolojisi Dergisi / Journal of Food and Feed Science - Technology 12:40-40 (2012)
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  • *Bu makalenin bir kısmıNAFI 2011 Uluslararası Gıda Kongresinde poster bildiri olarak sunulmuştur.
Toplam 155 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Makaleler
Yazarlar

Özgül Özdestan

Ali Üren Bu kişi benim

Yayımlanma Tarihi 8 Ağustos 2014
Yayımlandığı Sayı Yıl 2012 Sayı: 12

Kaynak Göster

APA Özdestan, Ö., & Üren, A. (2014). GIDALARDA BİYOJENAMİNLERLE İLGİLİ YASAL DÜZENLEMELER. Gıda Ve Yem Bilimi Teknolojisi Dergisi(12).

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Gıda ve Yem Bilimi-Teknolojisi Dergisi  CC BY-NC-ND 4.0 lisansı altında lisanslanmıştır
 Journal of Food and Feed Science-Technology is licensed under CC BY-NC-ND 4.0