A review: secondary metabolites of Uvaria chamae p. Beauv. (Annonaceae) and their biological activities
Abstract
Uvaria chamae p. Beauv., synthesizes and accumulates a variety of secondary metabolites from its root, stem, leaf and fruit. These consist mainly of essential oils, flavonoids, alkaloids and annonaceous acetogenins. Some of these biologically active secondary metabolites validate the claim made in traditional system of medicine. The present review summarizes the information available on the secondary metabolites isolated from U. chamae and their biological activities.
Keywords
Secondary metabolites,alkaloids,Essential oils,Flavonoids,Annonaceous acetogenins
References
- Abu T., Ajaiyeoba E.O., Abiodun O.O., Ogbole OO. 2018. Antioxidant and anti-inflammatory intestinal effect of Uvaria chamae P. Beauv (Annonaceae) in acetic acid-induced acute colitis in rats. Book of Abstract, The Nigerian society of Pharmacognosy (NSP) 30th AGM/14th scientific conference; Page 48.
- Achenbach, H., Hohn, M., Waibel, R., Nkunya, M.H.H., Jonker, S.A. & Muhie, S. (1997). Oxygenated pyrenes, their potential biosynthetic precursor and benzylated dihydroflavones from two African Uvaria species. Phytochemistry; 2:395-364. http://dx:doi.org/10.1016/s0031-9422(96) 00448-7.
- Adams, M.R. & Moss M.O. (1999). Food Microbiology. Cambridge: The Royal Society of Chemistry, pp. 471 – 476. Adepiti A.O., Taiwo, O.E., Dada, A.D. (2013). Evaluation of the in vivo antimalarial potentials of the leaf and fruit of Uvaria chamae P. Beauv. (Annonaceae). Planta medica, 013.
- Ake-Assi, L., Abeye, J., Guinko, S., Giguet, R. &Bangavou, Y. (1981). Contribution l’identificationet au recensement des plantes utilises dans la medicine traditionnelle et la pharmacopéeen. Republique Centrafricaine. Paris, Agencede Cooperation Culturelle et Technique.
- Alali, F.Q., Liu, X.X. & McLaughlin, J.L. (1999).Annonaceous acetogenins: Recent progress. J. Nat. Prod., 62, 504–540.http://dx:doi.org/10.1021/np980406d.
- Anam, E.M., Ekpa, O.D., Gariboldi, P.V., Morah, F.N.I. & Dosunmu, M.I. (1993). 6”-Hydroxybenzyl diuvaretins and related-compounds from Xylopia africana (Benth) Oliver. Indian J. Chem. B; 32:1051–1054.
- Arbonnier, M. (2000).Arbres, arbustesetlianes des zones sechesd’Afrique de l’ouest. CIRAD, MNHN, UICN. 541pp.
- Arbonnier, M. (2004).Trees, Shrubs and Lianas of West African Dry Zones. Germany: CIRAD Press Ltd. pp. 243 - 248.Verdict Press, p. 191.
- Awodiran, M.O., Adepiti, A.O. & Akinwunmi, K.F. (2017).Assessment of the cytotoxicity and genotoxicity properties of Uvaria chamae P. Beauv (Annonaceae) and Morinda lucida Benth (Rubiaceae) in mice. Drug and chemical toxicology, http://dx:doi.org/10.1080/01480545.2017.1365884.
- Ayedoun, M.A., Moudachirou, M., Adeoti, B.S., Menut, C., Lamaty, G. & Bessiére, J.M. (1999).Aromatic plants of Tropical West Africa. VII. Essential oil of leaf and root bark of Uvaria chamae P. Beauv. from Benin. Journal of Essential Oil Research 11:23-26. http://dx:doi.org/10.1080/10412905.1999.9701060.


