Year 2020, Volume 4 , Issue 4, Pages 394 - 399 2020-12-15

The antioxidant and antialzhemier activities of the Diplotaenia turcica with phytochemical analysis

Ugur OZDEK [1]

Diplotaenia turcica is an endemic plant that grows in eastern Turkey. This herb is used in herbal cheese, in meals and in traditional therapies. In this study, we aimed to examine some of the biochemical activities of this plant. Liquid chromatography-mass spectrometry (LC-MS) analysis was conducted on hydro alcohol extract of aerial part of DT. This analysis was applied to determine the total phenolic and flavonoid content, antioxidant and anti-alzheimer activities. LC-MS analysis showed that malic acid and quinic acid were found to be major compounds. The key flavonoids detected were hesperidine and rutine. The end of examination, the total amount of phenolic compound of extract was measured as 27.54 μg PEs/mg. And the total flavonoid amount was measured as 7.31 μg KEs/mg. β-carotene-linoleic acid test, DPPH free radical scavenging method, and ABTS cation radical scavenging outcomes were determined as IC50 of 169.71 μg/mL, 164.42 and 68.74 μg/mL, respectively. Cholinesterase inhibition test which indicate of alzheimer's did not inhibit acetylcholinesterase (AChE), but butyrylcholinesterase (BCHE) enzyme inhibition was 76.57%. As a result, further studies are needed in order to use Diplotaenia turcica plant for treatment or support purposes in the health field.
Diplotaenia turcica, Antialzhemier, Antioxidant, Activities
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Primary Language en
Subjects Environmental Sciences, Soil Science
Published Date December 2020
Journal Section Research Articles

Orcid: 0000-0002-0709-1545
Author: Ugur OZDEK (Primary Author)
Institution: Van Yuzuncu Yil University, Vocational School of Health Services, 65080 Van, Turkey
Country: Turkey

Thanks I would like to thank Mr. Mehmet Fırat for taxonomic examination of the plant and Mr. Mehmet Boğa for his support.

Application Date : July 24, 2020
Acceptance Date : September 23, 2020
Publication Date : December 15, 2020

APA Ozdek, U . (2020). The antioxidant and antialzhemier activities of the Diplotaenia turcica with phytochemical analysis . International Journal of Agriculture Environment and Food Sciences , 4 (4) , 394-399 . DOI: 10.31015/jaefs.2020.4.1