Yıl 2019,
Cilt: 4 Sayı: 3, 359 - 365, 30.12.2019
Selin Kalkan
,
Mehmet Soner Engin
,
Mustafa Remzi Otağ
Kaynakça
- Al-Seeni, M.N., (2011). Goji extract as antibacterial agent and antioxidant on Roridin E induced hepatotoxicity in male rat. Journal of International Environmental Application And Science, 6(1), 136-140.
- Amagase, H., and Nance, D.M., (2008). A randomized, double-blind, placebocontrolled, clinical study of the general effects of a standardized Lycium barbarum (goji) juice, GoChi. Journal of Alternative and Complementary Medicine, 14, 403-412.
- Ardağ, A., (2008). Antioksidan kapasite tayin yöntemlerinin analitik açıdan karşılaştırılması. Yüksek lisans tezi, Adnan Menderes Üniversitesi, Fen Bilimleri Enstitüsü, Aydın, Türkiye, 70s).
- Barontini, M., Bernini, R., Carastro, I., Gentili, P. and Romani, A., (2014). Synthesis and DPPH radical scavenging activity of novel compounds obtained from tyrosol and cinnamic acid derivatives. New Journal of Chemistry, 38, 809-816.
- Brand-Williams, W., Cavalier, M. E. and Berset, C., (1995). Use of free radical method to evaluate antioxidant activity. Food Science and Technology, 28(1): 25-30.
- Chang, R.C., and So, K.F., (2008). Use of anti-aging herbal medicine, Lycium barbarum, against aging-associated diseases. What do we know so far. Cellular and Molecular Neurobiology, 28(5), 643-52.
- Chao, J.C., Chiang, S.W., Wang, C.C., Tsai, Y.H., and Wu, M.S., (2006). Hot waterextracted Lycium barbarum and Rehmannia glutinosa inhibit proliferation and induce apoptosis of hepatocellular carcinoma cells. World Journal of Gastroenterology, 12(28), 4478-4484.
- CLSI., (2012). Performance Standards for Antimicrobial Susceptebility Testing. Twenty-second Informational Supplement. Clinical and Laboratory Standards Insitute, Wayne, PA, USA, M100-S22. 59p
- Engin, M.S., Kalkan, S., Çay, S., Güder, A., Otağ, M.R., Gür, G., and Kablan, A., (2018). DPPH Radical Scavenging, Phenolic and Antimicrobial Activity of Momordica charantia and Rheum ribes. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 9(4): 447-458.Gan, L., Zhang, S.H., Yang, X. L., & Xu, H.B. (2004). Immunomodulation and antitumor activity by a polysaccharide-protein complex from Lycium barbarum. International Immunopharmacology, 4, 563-569.
- Gong, X., and Rubin, L.P. (2015). Role of macular xanthophylls in prevention of common neovascular retinopathies: Retinopathy of prematurity and diabetic retinopathy. Archives of Biochemistry and Biophysics, 572, 40-48.
- Guo, D.J., Cheng, H.L., Chan, S.W.,and Yu, P.H.F., (2008). Antioxidative activities and the total phenolic contents of tonic Chinese medicinal herbs. Inflammopharmacology, 16, 201-207.
- Haytowitz, D.B., Bhagwat, S., (2010). Database for the oxygen radical absorbance capacity (ORAC) of selected foods, Release 2. Washington (DC): US Department of Agriculture;
- Hsu, H.Y., Yang, J.J., Ho, Y.H., and Lin, C.C., (1999). Difference in the effects of radioprotection between aerial and root parts of Lycium chinense. Journal of Ethnopharmacology, 64(2), 101-108.
- Huang, Y., Lu, J., and Shen, Y. (1999). The protective effects of total flavonoids from Lycium Barbarum L. on lipid peroxidation of liver mitochondria and red blood cell in rats. Wei sheng yan jiu= Journal of hygiene research, 28(2), 115-116.
- Ionica, E.M., Nour, V., and Trandafir, I., (2012). Polyphenols content and antioxidant capacity of goji fruits (Lycium chinense). South Western Journal of Horticulture, Biology and Environment, 3(2), 121-129.
- Jiang, L., (2014). Preparation and antioxidant activity of Lycium barbarum oligosaccharides. Carbohydrate Polymers, 99, 646-648.
- Kosar, M., Altintas, A., Kirimer, N., and Baser, K.H.C., (2003). Determination of the free radicals scavenging activity of Lycium extracts. Chemistry of Natural Compounds, 39, 439-442.
- Li, X., and Zhou, A., (2007). Evaluation of the antioxidant effects of polysaccharides extracted from Lycium barbarum. Medicinal Chemistry Research, 15, 471-482.
- Lin, C., Wang, C., and Chang, S., (2009). Antioxidative activity of polysaccharide fractions isolated from Lycium barbarum Linnaeus. International Journal of Biological Macromolecules, 45, 146-151.
- Manikandan, R., Thiagarajan, R., Goutham, G., Arumugam, M., Beulaja, M., ... Nabavi, S.M. (2016). Zeaxanthin and ocular health, from bench to bedside. Fitoterapia, 109, 58-66.
- Medina, M.B. (2011). Determination of the total phenolics in juices and superfruits by a novel chemical method. Journal of Functional Foods, 3, 79–87.
- Noshada, M. ,Hojjatia, M., and Behbahani, B.A., (2018). Black Zira essential oil: Chemical compositions and antimicrobial activity against the growth of some pathogenic strain causing infection. Microbial Pathogenesis, 116, 153-157.
- Peng, Y., Ma, C., Li, Y., Leung, K.S.Y., Jiang, Z.H., and Zhao, Z., (2005). Quantification of zeaxanthin dipalmitate and total carotenoids in Lycium fruits (Fructus Lycii). Plant Foods for Human Nutrition, 60, 161–164. Potterat, O. (2010). Phytochemistry, pharmacology and safety in the perspective of traditional uses and recent popularity. Planta Medica, 76, 7-19.
- Qian, J.Y., Liu, D., and Huang, A.G., (2004). The efficiency of flavonoids in polar extracts of Lycium chinense Mill. fruits as free radical scavenger. Food Chemistry, 87(2), 283-288.
- Skenderidis, P., Mitsagga, C., Giavasis, I., Petrotos, K., Lampakis, D., Leontopoulos, & Tsakalof, A., (2019). The in vitro antimicrobial activity assessment of ultrasound assisted Lycium barbarum fruit extracts and pomegranate fruit peels. Journal of Food Measurement and Characterization, 1-15.
- Sze, S. C. W., Song, J. X., Wong, R. N. S., Feng, Y. B., Ng, T. B., Tong, Y., & Zhang, K. Y. B. (2008). Application of SCAR (sequence characterized amplified region) analysis to authenticate Lycium barbarum (wolfberry) and its adulterants. Biotechnology and Applied Biochemistry, 51(1), 15-21.
- Türkmen, F.U., Mercimek Takcı, H.A., Sarıgüllü Önalan, F.E., Sağlam, H., (2019). Arum dioscoridis ekstraktlarının toplam fenolik, flavonoid içerikleri ile antioksidan ve antibakteriyel aktivitelerinin araştırılması. Harran Üniversitesi Mühendislik Dergisi, 4(1), 102-108.
- Ulusoy, E., Kolayli, S., and Sarikaya, A.O., (2010). Antioxidant and antimicrobial activity of different floral origin honeys from Turkiye. Journal of Food Biochemistry, 34, 321-335.
- Wang C.C., Chang S.C., Inbaraj B.S., and Chen B.H., (2010). Isolation of carotenoids, flavonoids and polysaccharides from Lycium barbarum L. and evaluation of antioxidant activity. Food Chemistry, 120, 184-192.
- Yin, G., and Dang, Y., (2008). Optimization of extraction technology of the Lycium barbarum polysaccharides by Box–Behnken statistical design. Carbohydrate Polymers, 74(3), 603-610.
- Yu, M.S., Leung, S.K., Lai, S.W., Che, C.M., Zee, S.Y., So, K.F., Yuen, WH., and Chang, R.C.C., (2005). Neuroprotective effects of anti-aging oriental medicine Lycium barbarum against beta-amyloid peptide neurotoxicity. Experimental Gerontology, 40(8), 716-727.
- Zhang, Z., Liu, X., Wu, T., Liu, J., Zhang, X., Yang, X., and Wang, Y., (2011a). Selective suppression of cervical cancer Hela cells by 2-O-β-Dglucopyranosyl- L-ascorbic acid isolated from the fruit of Lycium barbarum L. Cell Biology and Toxicology, 27, 107-121.
- Zhang, Z., Liu, X., Zhang, X., Liu, J., Hao, Y., (2011b). Comparative evaluation of the antioxidant effects of the natural vitamin C analog 2-O-β-D-glucopyranosyl-L-ascorbic acid isolated from Goji berry fruit. Archives of Pharmacal Research, 34, 801-810.
- Zhang, J., (2013). Antioxidant Properties of Goji Berries. Wayne State University Theses. 250p.
- Zhang, K. Y., Leung, H. W., Yeung, H. W., and Wong, R. N. (2001). Differentiation of Lycium barbarum from its related Lycium species using random amplified polymorphic DNA. Planta medica, 67(4), 379-381.
Gojiberry (Lycium barbarum L.) Meyvesinin Farklı Çözgenlerden Elde Edilen Ekstratlarının Toplam Fenolik İçerikleri İle Antioksidan ve Antimikrobiyal Aktivitelerinin Karşılaştırılması
Yıl 2019,
Cilt: 4 Sayı: 3, 359 - 365, 30.12.2019
Selin Kalkan
,
Mehmet Soner Engin
,
Mustafa Remzi Otağ
Öz
Bu çalışmada besleyici ve antioksidan
özelliklere sahip bir "süper gıda" olarak kabul edilen Goji
berry (Lycium barbarum L.) asetik asit+su ve etanol ektraktlarının toplam
fenolik madde miktarı ile antioksidan ve antimikrobiyel aktiviteleri gibi
biyoaktif özellikleri incelenmiştir. Farklı çözücüler kullanılarak hazırlanan
ektratlarda en yüksek toplam fenolik madde içeriği 5148
µg GAE/g ile etanolde tespit edilmiştir. Antioksidan aktivite
sonuçlarına göre en yüksek DPPH inhibisyonu %68,92 olarak asetik asit+su
ektraktında belirlenmiştir. Disk difüzyon yöntemine göre ekstraktların
antimikrobiyel özellikleri değerlendirildiğinde test mikroorganizmalarından Staphylococcus aureus ve Listeria
monocytogenes’ e karşı güçlü bir antimikrobiyel etkiye sahip oldukları
tespit edilmiştir.
Kaynakça
- Al-Seeni, M.N., (2011). Goji extract as antibacterial agent and antioxidant on Roridin E induced hepatotoxicity in male rat. Journal of International Environmental Application And Science, 6(1), 136-140.
- Amagase, H., and Nance, D.M., (2008). A randomized, double-blind, placebocontrolled, clinical study of the general effects of a standardized Lycium barbarum (goji) juice, GoChi. Journal of Alternative and Complementary Medicine, 14, 403-412.
- Ardağ, A., (2008). Antioksidan kapasite tayin yöntemlerinin analitik açıdan karşılaştırılması. Yüksek lisans tezi, Adnan Menderes Üniversitesi, Fen Bilimleri Enstitüsü, Aydın, Türkiye, 70s).
- Barontini, M., Bernini, R., Carastro, I., Gentili, P. and Romani, A., (2014). Synthesis and DPPH radical scavenging activity of novel compounds obtained from tyrosol and cinnamic acid derivatives. New Journal of Chemistry, 38, 809-816.
- Brand-Williams, W., Cavalier, M. E. and Berset, C., (1995). Use of free radical method to evaluate antioxidant activity. Food Science and Technology, 28(1): 25-30.
- Chang, R.C., and So, K.F., (2008). Use of anti-aging herbal medicine, Lycium barbarum, against aging-associated diseases. What do we know so far. Cellular and Molecular Neurobiology, 28(5), 643-52.
- Chao, J.C., Chiang, S.W., Wang, C.C., Tsai, Y.H., and Wu, M.S., (2006). Hot waterextracted Lycium barbarum and Rehmannia glutinosa inhibit proliferation and induce apoptosis of hepatocellular carcinoma cells. World Journal of Gastroenterology, 12(28), 4478-4484.
- CLSI., (2012). Performance Standards for Antimicrobial Susceptebility Testing. Twenty-second Informational Supplement. Clinical and Laboratory Standards Insitute, Wayne, PA, USA, M100-S22. 59p
- Engin, M.S., Kalkan, S., Çay, S., Güder, A., Otağ, M.R., Gür, G., and Kablan, A., (2018). DPPH Radical Scavenging, Phenolic and Antimicrobial Activity of Momordica charantia and Rheum ribes. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 9(4): 447-458.Gan, L., Zhang, S.H., Yang, X. L., & Xu, H.B. (2004). Immunomodulation and antitumor activity by a polysaccharide-protein complex from Lycium barbarum. International Immunopharmacology, 4, 563-569.
- Gong, X., and Rubin, L.P. (2015). Role of macular xanthophylls in prevention of common neovascular retinopathies: Retinopathy of prematurity and diabetic retinopathy. Archives of Biochemistry and Biophysics, 572, 40-48.
- Guo, D.J., Cheng, H.L., Chan, S.W.,and Yu, P.H.F., (2008). Antioxidative activities and the total phenolic contents of tonic Chinese medicinal herbs. Inflammopharmacology, 16, 201-207.
- Haytowitz, D.B., Bhagwat, S., (2010). Database for the oxygen radical absorbance capacity (ORAC) of selected foods, Release 2. Washington (DC): US Department of Agriculture;
- Hsu, H.Y., Yang, J.J., Ho, Y.H., and Lin, C.C., (1999). Difference in the effects of radioprotection between aerial and root parts of Lycium chinense. Journal of Ethnopharmacology, 64(2), 101-108.
- Huang, Y., Lu, J., and Shen, Y. (1999). The protective effects of total flavonoids from Lycium Barbarum L. on lipid peroxidation of liver mitochondria and red blood cell in rats. Wei sheng yan jiu= Journal of hygiene research, 28(2), 115-116.
- Ionica, E.M., Nour, V., and Trandafir, I., (2012). Polyphenols content and antioxidant capacity of goji fruits (Lycium chinense). South Western Journal of Horticulture, Biology and Environment, 3(2), 121-129.
- Jiang, L., (2014). Preparation and antioxidant activity of Lycium barbarum oligosaccharides. Carbohydrate Polymers, 99, 646-648.
- Kosar, M., Altintas, A., Kirimer, N., and Baser, K.H.C., (2003). Determination of the free radicals scavenging activity of Lycium extracts. Chemistry of Natural Compounds, 39, 439-442.
- Li, X., and Zhou, A., (2007). Evaluation of the antioxidant effects of polysaccharides extracted from Lycium barbarum. Medicinal Chemistry Research, 15, 471-482.
- Lin, C., Wang, C., and Chang, S., (2009). Antioxidative activity of polysaccharide fractions isolated from Lycium barbarum Linnaeus. International Journal of Biological Macromolecules, 45, 146-151.
- Manikandan, R., Thiagarajan, R., Goutham, G., Arumugam, M., Beulaja, M., ... Nabavi, S.M. (2016). Zeaxanthin and ocular health, from bench to bedside. Fitoterapia, 109, 58-66.
- Medina, M.B. (2011). Determination of the total phenolics in juices and superfruits by a novel chemical method. Journal of Functional Foods, 3, 79–87.
- Noshada, M. ,Hojjatia, M., and Behbahani, B.A., (2018). Black Zira essential oil: Chemical compositions and antimicrobial activity against the growth of some pathogenic strain causing infection. Microbial Pathogenesis, 116, 153-157.
- Peng, Y., Ma, C., Li, Y., Leung, K.S.Y., Jiang, Z.H., and Zhao, Z., (2005). Quantification of zeaxanthin dipalmitate and total carotenoids in Lycium fruits (Fructus Lycii). Plant Foods for Human Nutrition, 60, 161–164. Potterat, O. (2010). Phytochemistry, pharmacology and safety in the perspective of traditional uses and recent popularity. Planta Medica, 76, 7-19.
- Qian, J.Y., Liu, D., and Huang, A.G., (2004). The efficiency of flavonoids in polar extracts of Lycium chinense Mill. fruits as free radical scavenger. Food Chemistry, 87(2), 283-288.
- Skenderidis, P., Mitsagga, C., Giavasis, I., Petrotos, K., Lampakis, D., Leontopoulos, & Tsakalof, A., (2019). The in vitro antimicrobial activity assessment of ultrasound assisted Lycium barbarum fruit extracts and pomegranate fruit peels. Journal of Food Measurement and Characterization, 1-15.
- Sze, S. C. W., Song, J. X., Wong, R. N. S., Feng, Y. B., Ng, T. B., Tong, Y., & Zhang, K. Y. B. (2008). Application of SCAR (sequence characterized amplified region) analysis to authenticate Lycium barbarum (wolfberry) and its adulterants. Biotechnology and Applied Biochemistry, 51(1), 15-21.
- Türkmen, F.U., Mercimek Takcı, H.A., Sarıgüllü Önalan, F.E., Sağlam, H., (2019). Arum dioscoridis ekstraktlarının toplam fenolik, flavonoid içerikleri ile antioksidan ve antibakteriyel aktivitelerinin araştırılması. Harran Üniversitesi Mühendislik Dergisi, 4(1), 102-108.
- Ulusoy, E., Kolayli, S., and Sarikaya, A.O., (2010). Antioxidant and antimicrobial activity of different floral origin honeys from Turkiye. Journal of Food Biochemistry, 34, 321-335.
- Wang C.C., Chang S.C., Inbaraj B.S., and Chen B.H., (2010). Isolation of carotenoids, flavonoids and polysaccharides from Lycium barbarum L. and evaluation of antioxidant activity. Food Chemistry, 120, 184-192.
- Yin, G., and Dang, Y., (2008). Optimization of extraction technology of the Lycium barbarum polysaccharides by Box–Behnken statistical design. Carbohydrate Polymers, 74(3), 603-610.
- Yu, M.S., Leung, S.K., Lai, S.W., Che, C.M., Zee, S.Y., So, K.F., Yuen, WH., and Chang, R.C.C., (2005). Neuroprotective effects of anti-aging oriental medicine Lycium barbarum against beta-amyloid peptide neurotoxicity. Experimental Gerontology, 40(8), 716-727.
- Zhang, Z., Liu, X., Wu, T., Liu, J., Zhang, X., Yang, X., and Wang, Y., (2011a). Selective suppression of cervical cancer Hela cells by 2-O-β-Dglucopyranosyl- L-ascorbic acid isolated from the fruit of Lycium barbarum L. Cell Biology and Toxicology, 27, 107-121.
- Zhang, Z., Liu, X., Zhang, X., Liu, J., Hao, Y., (2011b). Comparative evaluation of the antioxidant effects of the natural vitamin C analog 2-O-β-D-glucopyranosyl-L-ascorbic acid isolated from Goji berry fruit. Archives of Pharmacal Research, 34, 801-810.
- Zhang, J., (2013). Antioxidant Properties of Goji Berries. Wayne State University Theses. 250p.
- Zhang, K. Y., Leung, H. W., Yeung, H. W., and Wong, R. N. (2001). Differentiation of Lycium barbarum from its related Lycium species using random amplified polymorphic DNA. Planta medica, 67(4), 379-381.