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Fatty Acid Analysis and Biological Activity of Jordanian Propolis

Year 2018, Volume: 1 Issue: 3 - 2nd Propolis Conference Special Issue, 33 - 33, 08.12.2018

Ashok K. Shakya Shankar Katekhaye Ghaleb A. Orıquat Rajashri R. Naık Rajashri R. Naık Anant Paradkar Hugo Fearnley James Fearnley

https://izlik.org/JA97AR35XP

Abstract

Propolis is a resinous
natural product collected by bees (Apis
mellifera) from tree exudates which is widely used in folk medicine1.
Reports on Jordanian Propolis reveal the presence of new chemical compound
4(Z)-1-3-dihydroxyeupha-7,24-dien-26-oic acid2 along with other
compounds like pinobanksin-3-O-acetate,
pinocemberin, chrysin3 and lignoceric acid2. The
present study was carried out to investigate the fatty acid composition,
antioxidant and xanthine oxidase inhibition activity of Jordanian Propolis,
collected from Al-Ghour region. The hexane extract of Jordanian Propolis
contains different fatty acids, which are reported first time, using GC-FID. The
major fatty acid identified were palmitic acid (44.5%), Oleic acid (18:1∆9cis, 24.6%), Arachidic acid (7.4%), Stearic acid (5.4%),
linoleic acid (18:2∆9-12cis, 3.1%), caprylic acid
(2.9%),  lignoceric acid (2.6%), cis-11,14-eicosadienoic acid (20:2∆11-14cis, 2.4%), palmitoleic
acid (1.5%), cis-11-eicosenoic acid (1.2%), α–linolenic acid (18:3∆9-12-15cis, 1.1%), cis-13,16-docosadienoic acid (22:2∆13-16cis, 1.0%), along with
minor constituents like saturated fatty acids. Antioxidant properties of the
hexane extract were determined via DPPH radical scavenging, β-carotene
bleaching assay and NO scavenging assay. The extract produced significant
antioxidant activity in-vitro. The
extract also exhibit appreciable xanthine oxidase inhibitory activity in-vitro.

Keywords

Propolis Naturel product DPPH In vitro

References

  • 1. Toreti, V.C., Sato, H.H., Pastore, G.M. and Park, Y.K., 2013. Recent progress of propolis for its biological and chemical compositions and its botanical origin. Evidence-based complementary and alternative medicine, 2013. http://dx.doi.org/10.1155/2013/697390
  • 2. Shaheen, S.A., Zarga, M.H.A., Nazer, I.K., Darwish, R.M. and Al-Jaber, H.I., 2011. Chemical constituents of Jordanian propolis. Natural product research, 25(14), 1312-1318.
  • 3. Darwish, R.M., Ra'ed, J., Zarga, M.H.A. and Nazer, I.K., 2010. Antibacterial effect of Jordanian propolis and isolated flavonoids against human pathogenic bacteria. African Journal of Biotechnology, 9(36). 5966-5974

Year 2018, Volume: 1 Issue: 3 - 2nd Propolis Conference Special Issue, 33 - 33, 08.12.2018

Ashok K. Shakya Shankar Katekhaye Ghaleb A. Orıquat Rajashri R. Naık Rajashri R. Naık Anant Paradkar Hugo Fearnley James Fearnley

https://izlik.org/JA97AR35XP

Abstract

References

  • 1. Toreti, V.C., Sato, H.H., Pastore, G.M. and Park, Y.K., 2013. Recent progress of propolis for its biological and chemical compositions and its botanical origin. Evidence-based complementary and alternative medicine, 2013. http://dx.doi.org/10.1155/2013/697390
  • 2. Shaheen, S.A., Zarga, M.H.A., Nazer, I.K., Darwish, R.M. and Al-Jaber, H.I., 2011. Chemical constituents of Jordanian propolis. Natural product research, 25(14), 1312-1318.
  • 3. Darwish, R.M., Ra'ed, J., Zarga, M.H.A. and Nazer, I.K., 2010. Antibacterial effect of Jordanian propolis and isolated flavonoids against human pathogenic bacteria. African Journal of Biotechnology, 9(36). 5966-5974
There are 3 citations in total.

Details

Primary Language English
Journal Section Conference Paper
Authors

Ashok K. Shakya This is me

Shankar Katekhaye This is me

Ghaleb A. Orıquat This is me

Rajashri R. Naık This is me

Rajashri R. Naık This is me

Anant Paradkar This is me

Hugo Fearnley This is me

James Fearnley This is me

Publication Date December 8, 2018
IZ https://izlik.org/JA97AR35XP
Published in Issue Year 2018 Volume: 1 Issue: 3 - 2nd Propolis Conference Special Issue

Cite

APA Shakya, A. K., Katekhaye, S., Orıquat, G. A., Naık, R. R., Naık, R. R., Paradkar, A., Fearnley, H., & Fearnley, J. (2018). Fatty Acid Analysis and Biological Activity of Jordanian Propolis. Journal of Apitherapy and Nature, 1(3), 33-33. https://izlik.org/JA97AR35XP
AMA 1.Shakya AK, Katekhaye S, Orıquat GA, et al. Fatty Acid Analysis and Biological Activity of Jordanian Propolis. J.Apit.Nat. 2018;1(3):33-33. https://izlik.org/JA97AR35XP
Chicago Shakya, Ashok K., Shankar Katekhaye, Ghaleb A. Orıquat, et al. 2018. “Fatty Acid Analysis and Biological Activity of Jordanian Propolis”. Journal of Apitherapy and Nature 1 (3): 33-33. https://izlik.org/JA97AR35XP.
EndNote Shakya AK, Katekhaye S, Orıquat GA, Naık RR, Naık RR, Paradkar A, Fearnley H, Fearnley J (December 1, 2018) Fatty Acid Analysis and Biological Activity of Jordanian Propolis. Journal of Apitherapy and Nature 1 3 33–33.
IEEE [1]A. K. Shakya et al., “Fatty Acid Analysis and Biological Activity of Jordanian Propolis”, J.Apit.Nat., vol. 1, no. 3, pp. 33–33, Dec. 2018, [Online]. Available: https://izlik.org/JA97AR35XP
ISNAD Shakya, Ashok K. - Katekhaye, Shankar - Orıquat, Ghaleb A. - Naık, Rajashri R. - Naık, Rajashri R. - Paradkar, Anant - Fearnley, Hugo - Fearnley, James. “Fatty Acid Analysis and Biological Activity of Jordanian Propolis”. Journal of Apitherapy and Nature 1/3 (December 1, 2018): 33-33. https://izlik.org/JA97AR35XP.
JAMA 1.Shakya AK, Katekhaye S, Orıquat GA, Naık RR, Naık RR, Paradkar A, Fearnley H, Fearnley J. Fatty Acid Analysis and Biological Activity of Jordanian Propolis. J.Apit.Nat. 2018;1:33–33.
MLA Shakya, Ashok K., et al. “Fatty Acid Analysis and Biological Activity of Jordanian Propolis”. Journal of Apitherapy and Nature, vol. 1, no. 3, Dec. 2018, pp. 33-33, https://izlik.org/JA97AR35XP.
Vancouver 1.Shakya AK, Katekhaye S, Orıquat GA, Naık RR, Naık RR, Paradkar A, et al. Fatty Acid Analysis and Biological Activity of Jordanian Propolis. J.Apit.Nat. [Internet]. 2018 Dec. 1;1(3):33-. Available from: https://izlik.org/JA97AR35XP

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