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Elektrofizyolojinin Tarihsel Serüveni: Galvani Sonrası Galvanizm

Year 2022, , 247 - 261, 30.05.2022
https://doi.org/10.31020/mutftd.1037800

Abstract

Elektrofizyolojinin tarihsel sürecini konu aldığımız bu çalışmada Galvani sonrası erken dönem değerlendirilmiştir. Galvani’nin deneylerini onun ölümünden sonra da tekrarlayan Alessandro Volta, çalışmalarını “volta pili” olarak bilinen “sürekli akım kaynağı” buluşu ile taçlandırmıştır. Volta pili, Galvani’nin “canlı elektriği” teorisinde tanımladığı doğal elektrik organını taklit edercesine, aralarında tuzlu suyla ıslatılmış mukavva katmanların bulunduğu iki farklı metalin üst üste diziliminden oluşuyordu. Galvani’nin ölümünden sonra yeğeni, fizikçi Giovanni Aldini, “yeniden canlandırma” deneyleriyle “canlı elektriği” teorisine farklı bir tartışma boyutu kazandırdı. Dayısının aksine Volta’ya daha yakın olan Aldini, reanimasyon deneylerinde Volta pili kullanarak, sonradan “galvanizm” olarak anılan teoriyi tanıtma ve yaygınlaştırma çabasında bulundu. Aldini’nin bu çabaları, “galvanik tedavi” adı altında birçok çalışmayı da tetiklemiş oldu. Faraday’ın “manyetik indüksiyon” kavramı önermesi ve “manyetik bobin” geliştirmesi sonrasında Duchenne de Boulogne, galvanik ve alternatif akımın farklı biyolojik etkilerini ortaya koyarak birçok yanlış uygulamanın yaygınlaşmasını engellemiş olacaktı. Bunun yanı sıra, Galvani’nin önermeleri ve Aldini’nin provokatif çalışmaları, Mary Shelley’nin “Frankenstein” adlı romanında olduğu gibi birçok bilim kurgu eser için de ilham kaynağı olmuştur.
Galvani’den sonra canlı elektriği ile ilgili dönemin en önemli buluşunu Carlo Matteucci yapacaktı. Matteucci, torpil (torpedo) balığının beyin sapındaki “elektrik lob” adı verilen özel bir yapının elektrik deşarjlarını kontrol ettiğini gösterdi. Daha sonra Matteucci, “biyolojik pil“ kavramını bilim dünyasına kazandırarak “elektrik deşarj” ve “aksiyon akımı” önermelerinde de bulunacaktır. Takip eden dönemlerde elektromotor kuvvet birimi olarak “Volt” seçimi, “galvanizm”, “galvanik akım” ve “galvanometre” kavramları ile, Volta ve Galvani bilim camiası tarafından onurlandırılmıştır.

References

  • 1. The Body Electric. Smithsonian Libraries and Archives; Available from: https://library.si.edu/exhibition/fantastic-worlds/body-electric (Erişim tarihi: 15.11.2021).
  • 2. Brown A.S. The science that made Frankenstein: How early experiments with electricity inspired Mary Shelley's reanimated monster. Available from: https://www.insidescience.org/news/science-made-frankenstein (Erişim Tarihi: 15.07.2021).
  • 3. Experiment: The beginning of Modern Neuroscience: The Galvani/Volta Debate. Available from: https://backyardbrains.com/ experiments/Galvani_Volta (Erişim Traihi:15.11.2021).
  • 4. Parent A. Giovanni Aldini: From animal electricity to human brain stimulation. Can. J. Neurol. Sci 2004;31:576-584.
  • 5. Verkhratsky A, Parpura V. History of electrophysiology and the patch clamp. Methods in Molecular Biology 2014;1183:1-19.
  • 6. Wu CH. Electric fish and the discovery of animal electricity: The mystery of the electric fish motivated research into electricity and was instrumental in the emergence of electrophysiology. American Scientsit 1984;72(6):598-607.
  • 7. Brasadola M. Medicine and science in the life of Luigi Galvani (1737-1798). Brain Research Bulletin 1988;46(5):367-80.
  • 8. Underwood E.A. Galvani and the discovery of ‘animal electricity’. Nature 1955;175:441-2.
  • 9. Cavazza M. Laura Bassi and Giuseppe Veratti: an electric couple during the Enlightenment. Contributions to Science 2009;5(1):115-28.
  • 10. Piccolino M. Women in Science: Laura Bassi et Adriana Fiorentini: realisations et difficultes de deux dames italiennes dans les sciences, au18eme et au20eme siecle. Available from: http://marcopiccolino.org/ (Erişim Tarihi: 15.11.2021)
  • 11. Kipnis N. Luigi Galvani and the debate on animal electricity, 1791-1800. Annals of Science 1987;44:107-42.
  • 12. Piccolino M. Animal electricity and the birth of electrophysiology: The legacy of Luigi Galvani. Brain research Bulletin 1998;46(5):381-407.
  • 13. Heilbron JL. The Contributions of Bologna to Galvanism. Historical Studies in the Physical and Biological Science 1991;22(1):57-85.
  • 14. Wu CH. Electric fish and the discovery of animal electricity: The mystery of the electric fish motivated research into electricity and was instrumental in the emergence of electrophysiology. American Scientsit 1984;72(6):598-607.
  • 15. Brasadola M. Medicine and science in the life of Luigi Galvani (1737-1798). Brain Research Bulletin 1988;46(5):367-80.
  • 16. Piccolino M. The bicentennial of the Voltaic battery (1800-2000): the artificial electronic organ. Trends Neurosci 2000;23:147-51.
  • 17. Finger S, Pİccolino M, Stahnisch FW. Alexander von Humboldt: Galvanis, Animal Electricity, and self-experimentation Part 2: The electric eel, animal electricity, and later years. Journal of the History of the Neurosciences 2013;22(4):327-52.
  • 18. Alessandro Volta. Available from: https://www.encyclopedia.com/people/history/ historians-miscellaneous-biographies/alessandro-volta (Erişim Tarihi:15.07.2021)
  • 19. Duke S. Battery technology has changed little since Volta, but are longer lasting batteries finally here? Scence Spinning 2015. Available from: https://i0.wp.com/ sciencespinning.com/wp-content/uploads/2015/09/voltas-battery.jpeg?ssl=1 (Erişim tarihi: 15.07.2021)
  • 20. Mc Comas AJ. Galvani’s Spark; The Story of the Nerve Impulse. Oxford University Press, New York 2011;3-47.
  • 21. npg 2515 (19); Giovanni Aldini. Available from: https://www.npg.org.uk/collections/ search/portrait/mw00077/Giovanni-Aldini (Erişim Tarihi: 15.11.2021).
  • 22. Partin C. Profiles in Cardiology: Alessandro Volta. Clin. Cardiol 2002;25:541-3.
  • 23. Montillo R. The Italian ‘Mad Scientist’ Whose Experiments Inspired Frankenstein. Italian Sons and Daughters of America, 2019. Available from: https://orderisda.org/culture/ literature/the-italian-mad-scientist-whose-experiments-inspired-frankenstein/ (Erişim Tarihi: 15.11.2021)
  • 24. Areas FZS, Areas GPT, Moll Neto R. Giovanni Aldini and his contributions to non-invasive brain stimulation. Arq. Neuro-Psiquiatr 2020;78(11):733-5.
  • 25. Giovanni Aldini, galvanism experiments Wellcome L0007024.jpg; Available from: https://tr.m.wikipedia.org/wiki/Dosya:Giovanni_Aldini,_galvanism_experiments_Wellcome_L0007024.jpg (Erişim Tarihi: 15.11.2021).
  • 26. Essai théorique et expérimental sur le galvanisme, avec une série d'expériences faites en présence des commissaires de l'Institut national de France, et en divers amphithéâtres de Londres, par Jean Aldini,…Avec planches. Available from: https://gallica.bnf.fr/ark:/ 12148/bpt6k61162023.texteImage (Erişim Tarihi: 15.11.2021) .
  • 27. Moruzzi G. The electrophysiological work of Carlo Matteucci.1964. Brain Res Bull 1996;40(2):69-91.
  • 28. Piccolino M, Wade NJ. Carlo Matteucci (1811-1868), the “frogs pile”, and the Risorgimento of electrophysiology. Cortex 2012;48:645-6.
  • 29. Walton G. Elisha Perkins: Eighteenth-century Metallic Tractor Inventor. Available from: https://www.geriwalton.com/elisha-perkins-eighteenth-century-metallic-tractor-inventor/ (Erişim Tarihi: 15.11.2021).
  • 30. The Odd Sallon. 1803: Giovanni Aldini attemts to reanimate the dead. Available from: https://www.oddsalon.com/jan-18-1803-giovanni-aldini-attempts-to-reanimate-the-dead/ (Erişim tarihi: 03.11.2021)
  • 31. Campbell EDR. The Achievement of Duchenne. Proc.Roy.Soc. Med. Section of Physical Medicine 1973;66:4-8,
  • 32. Piccolino M, Bresadola M. Drawing a spark from darkness: John Walsh and electric fish. TRENDS in Neurosciences 2002;25(1):51-7.
  • 33. Mary Wollstonecraft Shelley by Richard Rothwell © National Portrait Gallery, London. Available from: https://www.bl.uk/people/mary-shelley (Erişim Tarihi: 15.11.2021).
  • 34. Mary Shelley, Frankenstein; or, The Modern Prometheus. The most valuable boks in existance 2017. Available from: https://www.telegraph.co.uk/books/authors/the-most-valuable-rare-books-in-existence/mary-shelley-frankenstein-or-the-modern-prometheuslondon-for-lac/ (Erişim Tarihi: 15.11.2021).
  • 35. Carlo Matteucci (1811-1868): Profilo della vita e dell'opera. Catalogue search Wellcome Collection. Available from: https://wellcomecollection.org/ works?query=%22Matteucci,%20Carlo,%201811-1868.%22 (Erişim Tarihi: 15.11.2021).
  • 36. Finger S, Piccolino M. The shocking history of electric fishes. From anicient epoches to the birth of modern neurophysiology. Oxford University Press, New York 2011; 3-201.
  • 37. Tsoucalas G. et al. The “torpedo” effect in medicine. Int Marit Health 2014;64(2):65–7.

Historical Perspective on Early Electrophysiology: Galvanism After Galvani

Year 2022, , 247 - 261, 30.05.2022
https://doi.org/10.31020/mutftd.1037800

Abstract

This study reviews the electrophysiological developments right after Galvani form the historical perspective. Volta, repeating the Galvani's experiments, would lead the invention of battery. The first battery consisted of two different metals placed on top of each other, with layers of cardboard soaked in salty water in between, mimicking the natural electric organ that Galvani described earlier. After the death of Galvani, his nephew, physicist Giovanni Aldini, has brought different dimension of discussion to Galvani’s "animal electricity" theory with his provocative "reanimation" experiments. He used voltaic pile in his demonstrations of “galvanism”. Aldini’s efforts triggered so many medical applications under "galvanic therapy". Thanks to Faraday's proposal of the concept of "magnetic induction" and his invention of "magnetic coil", Duchenne worked with both galvanic and alternating currents for the treatment of certain neuropathic diseases, thus preventing the fantastic misuse of electric current on patients. Galvani's theory and the experiments, specifically Aldini’s demonstrations had also been the source of inspiration for many works of science fiction, such as Mary Shelley's novel "Frankenstein".
After Galvani, Carlo Matteucci would make the most important invention regarding the animal electricity. Matteucci showed a special structure in the torpedo's brain stem, called as "electric lobe" which controls the activity of electric organ. Later, Matteucci would introduce the concept of "biological pile" and make suggestion of phenomenon "electric discharge" and "action current". The history of science honored Volta by using his name as the unit of electromotive force and Galvani by using the terms “galvanism”, “galvanic current” “galvanometer”.

References

  • 1. The Body Electric. Smithsonian Libraries and Archives; Available from: https://library.si.edu/exhibition/fantastic-worlds/body-electric (Erişim tarihi: 15.11.2021).
  • 2. Brown A.S. The science that made Frankenstein: How early experiments with electricity inspired Mary Shelley's reanimated monster. Available from: https://www.insidescience.org/news/science-made-frankenstein (Erişim Tarihi: 15.07.2021).
  • 3. Experiment: The beginning of Modern Neuroscience: The Galvani/Volta Debate. Available from: https://backyardbrains.com/ experiments/Galvani_Volta (Erişim Traihi:15.11.2021).
  • 4. Parent A. Giovanni Aldini: From animal electricity to human brain stimulation. Can. J. Neurol. Sci 2004;31:576-584.
  • 5. Verkhratsky A, Parpura V. History of electrophysiology and the patch clamp. Methods in Molecular Biology 2014;1183:1-19.
  • 6. Wu CH. Electric fish and the discovery of animal electricity: The mystery of the electric fish motivated research into electricity and was instrumental in the emergence of electrophysiology. American Scientsit 1984;72(6):598-607.
  • 7. Brasadola M. Medicine and science in the life of Luigi Galvani (1737-1798). Brain Research Bulletin 1988;46(5):367-80.
  • 8. Underwood E.A. Galvani and the discovery of ‘animal electricity’. Nature 1955;175:441-2.
  • 9. Cavazza M. Laura Bassi and Giuseppe Veratti: an electric couple during the Enlightenment. Contributions to Science 2009;5(1):115-28.
  • 10. Piccolino M. Women in Science: Laura Bassi et Adriana Fiorentini: realisations et difficultes de deux dames italiennes dans les sciences, au18eme et au20eme siecle. Available from: http://marcopiccolino.org/ (Erişim Tarihi: 15.11.2021)
  • 11. Kipnis N. Luigi Galvani and the debate on animal electricity, 1791-1800. Annals of Science 1987;44:107-42.
  • 12. Piccolino M. Animal electricity and the birth of electrophysiology: The legacy of Luigi Galvani. Brain research Bulletin 1998;46(5):381-407.
  • 13. Heilbron JL. The Contributions of Bologna to Galvanism. Historical Studies in the Physical and Biological Science 1991;22(1):57-85.
  • 14. Wu CH. Electric fish and the discovery of animal electricity: The mystery of the electric fish motivated research into electricity and was instrumental in the emergence of electrophysiology. American Scientsit 1984;72(6):598-607.
  • 15. Brasadola M. Medicine and science in the life of Luigi Galvani (1737-1798). Brain Research Bulletin 1988;46(5):367-80.
  • 16. Piccolino M. The bicentennial of the Voltaic battery (1800-2000): the artificial electronic organ. Trends Neurosci 2000;23:147-51.
  • 17. Finger S, Pİccolino M, Stahnisch FW. Alexander von Humboldt: Galvanis, Animal Electricity, and self-experimentation Part 2: The electric eel, animal electricity, and later years. Journal of the History of the Neurosciences 2013;22(4):327-52.
  • 18. Alessandro Volta. Available from: https://www.encyclopedia.com/people/history/ historians-miscellaneous-biographies/alessandro-volta (Erişim Tarihi:15.07.2021)
  • 19. Duke S. Battery technology has changed little since Volta, but are longer lasting batteries finally here? Scence Spinning 2015. Available from: https://i0.wp.com/ sciencespinning.com/wp-content/uploads/2015/09/voltas-battery.jpeg?ssl=1 (Erişim tarihi: 15.07.2021)
  • 20. Mc Comas AJ. Galvani’s Spark; The Story of the Nerve Impulse. Oxford University Press, New York 2011;3-47.
  • 21. npg 2515 (19); Giovanni Aldini. Available from: https://www.npg.org.uk/collections/ search/portrait/mw00077/Giovanni-Aldini (Erişim Tarihi: 15.11.2021).
  • 22. Partin C. Profiles in Cardiology: Alessandro Volta. Clin. Cardiol 2002;25:541-3.
  • 23. Montillo R. The Italian ‘Mad Scientist’ Whose Experiments Inspired Frankenstein. Italian Sons and Daughters of America, 2019. Available from: https://orderisda.org/culture/ literature/the-italian-mad-scientist-whose-experiments-inspired-frankenstein/ (Erişim Tarihi: 15.11.2021)
  • 24. Areas FZS, Areas GPT, Moll Neto R. Giovanni Aldini and his contributions to non-invasive brain stimulation. Arq. Neuro-Psiquiatr 2020;78(11):733-5.
  • 25. Giovanni Aldini, galvanism experiments Wellcome L0007024.jpg; Available from: https://tr.m.wikipedia.org/wiki/Dosya:Giovanni_Aldini,_galvanism_experiments_Wellcome_L0007024.jpg (Erişim Tarihi: 15.11.2021).
  • 26. Essai théorique et expérimental sur le galvanisme, avec une série d'expériences faites en présence des commissaires de l'Institut national de France, et en divers amphithéâtres de Londres, par Jean Aldini,…Avec planches. Available from: https://gallica.bnf.fr/ark:/ 12148/bpt6k61162023.texteImage (Erişim Tarihi: 15.11.2021) .
  • 27. Moruzzi G. The electrophysiological work of Carlo Matteucci.1964. Brain Res Bull 1996;40(2):69-91.
  • 28. Piccolino M, Wade NJ. Carlo Matteucci (1811-1868), the “frogs pile”, and the Risorgimento of electrophysiology. Cortex 2012;48:645-6.
  • 29. Walton G. Elisha Perkins: Eighteenth-century Metallic Tractor Inventor. Available from: https://www.geriwalton.com/elisha-perkins-eighteenth-century-metallic-tractor-inventor/ (Erişim Tarihi: 15.11.2021).
  • 30. The Odd Sallon. 1803: Giovanni Aldini attemts to reanimate the dead. Available from: https://www.oddsalon.com/jan-18-1803-giovanni-aldini-attempts-to-reanimate-the-dead/ (Erişim tarihi: 03.11.2021)
  • 31. Campbell EDR. The Achievement of Duchenne. Proc.Roy.Soc. Med. Section of Physical Medicine 1973;66:4-8,
  • 32. Piccolino M, Bresadola M. Drawing a spark from darkness: John Walsh and electric fish. TRENDS in Neurosciences 2002;25(1):51-7.
  • 33. Mary Wollstonecraft Shelley by Richard Rothwell © National Portrait Gallery, London. Available from: https://www.bl.uk/people/mary-shelley (Erişim Tarihi: 15.11.2021).
  • 34. Mary Shelley, Frankenstein; or, The Modern Prometheus. The most valuable boks in existance 2017. Available from: https://www.telegraph.co.uk/books/authors/the-most-valuable-rare-books-in-existence/mary-shelley-frankenstein-or-the-modern-prometheuslondon-for-lac/ (Erişim Tarihi: 15.11.2021).
  • 35. Carlo Matteucci (1811-1868): Profilo della vita e dell'opera. Catalogue search Wellcome Collection. Available from: https://wellcomecollection.org/ works?query=%22Matteucci,%20Carlo,%201811-1868.%22 (Erişim Tarihi: 15.11.2021).
  • 36. Finger S, Piccolino M. The shocking history of electric fishes. From anicient epoches to the birth of modern neurophysiology. Oxford University Press, New York 2011; 3-201.
  • 37. Tsoucalas G. et al. The “torpedo” effect in medicine. Int Marit Health 2014;64(2):65–7.
There are 37 citations in total.

Details

Primary Language Turkish
Subjects Clinical Sciences
Journal Section Review
Authors

Erhan Kiziltan 0000-0001-6029-3835

Nizamettin Dalkılıç 0000-0002-2306-4467

Publication Date May 30, 2022
Submission Date December 17, 2021
Published in Issue Year 2022

Cite

APA Kiziltan, E., & Dalkılıç, N. (2022). Elektrofizyolojinin Tarihsel Serüveni: Galvani Sonrası Galvanizm. Mersin Üniversitesi Tıp Fakültesi Lokman Hekim Tıp Tarihi Ve Folklorik Tıp Dergisi, 12(2), 247-261. https://doi.org/10.31020/mutftd.1037800
AMA Kiziltan E, Dalkılıç N. Elektrofizyolojinin Tarihsel Serüveni: Galvani Sonrası Galvanizm. Mersin Üniversitesi Tıp Fakültesi Lokman Hekim Tıp Tarihi ve Folklorik Tıp Dergisi. May 2022;12(2):247-261. doi:10.31020/mutftd.1037800
Chicago Kiziltan, Erhan, and Nizamettin Dalkılıç. “Elektrofizyolojinin Tarihsel Serüveni: Galvani Sonrası Galvanizm”. Mersin Üniversitesi Tıp Fakültesi Lokman Hekim Tıp Tarihi Ve Folklorik Tıp Dergisi 12, no. 2 (May 2022): 247-61. https://doi.org/10.31020/mutftd.1037800.
EndNote Kiziltan E, Dalkılıç N (May 1, 2022) Elektrofizyolojinin Tarihsel Serüveni: Galvani Sonrası Galvanizm. Mersin Üniversitesi Tıp Fakültesi Lokman Hekim Tıp Tarihi ve Folklorik Tıp Dergisi 12 2 247–261.
IEEE E. Kiziltan and N. Dalkılıç, “Elektrofizyolojinin Tarihsel Serüveni: Galvani Sonrası Galvanizm”, Mersin Üniversitesi Tıp Fakültesi Lokman Hekim Tıp Tarihi ve Folklorik Tıp Dergisi, vol. 12, no. 2, pp. 247–261, 2022, doi: 10.31020/mutftd.1037800.
ISNAD Kiziltan, Erhan - Dalkılıç, Nizamettin. “Elektrofizyolojinin Tarihsel Serüveni: Galvani Sonrası Galvanizm”. Mersin Üniversitesi Tıp Fakültesi Lokman Hekim Tıp Tarihi ve Folklorik Tıp Dergisi 12/2 (May 2022), 247-261. https://doi.org/10.31020/mutftd.1037800.
JAMA Kiziltan E, Dalkılıç N. Elektrofizyolojinin Tarihsel Serüveni: Galvani Sonrası Galvanizm. Mersin Üniversitesi Tıp Fakültesi Lokman Hekim Tıp Tarihi ve Folklorik Tıp Dergisi. 2022;12:247–261.
MLA Kiziltan, Erhan and Nizamettin Dalkılıç. “Elektrofizyolojinin Tarihsel Serüveni: Galvani Sonrası Galvanizm”. Mersin Üniversitesi Tıp Fakültesi Lokman Hekim Tıp Tarihi Ve Folklorik Tıp Dergisi, vol. 12, no. 2, 2022, pp. 247-61, doi:10.31020/mutftd.1037800.
Vancouver Kiziltan E, Dalkılıç N. Elektrofizyolojinin Tarihsel Serüveni: Galvani Sonrası Galvanizm. Mersin Üniversitesi Tıp Fakültesi Lokman Hekim Tıp Tarihi ve Folklorik Tıp Dergisi. 2022;12(2):247-61.

Cited By

Elektrofizyolojinin Tarihsel Serüveni: Galvani Sonrası Geç Dönem
Mersin Üniversitesi Tıp Fakültesi Lokman Hekim Tıp Tarihi ve Folklorik Tıp Dergisi
https://doi.org/10.31020/mutftd.1228469
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