Effect of New Water-Soluble Dendritic Phthalocyanines on Human Colorectal and Liver Cancer Cell Lines

Year 2017, Volume: 21 Issue: 3, 689 - 695, 08.08.2017

Ebru Yabaş , Mustafa Sülü Aykut Özgür Yusuf Tutar

https://doi.org/10.19113/sdufbed.89035

Cited By: 1

Abstract

Human hepatocellular carcinoma (HepG2) cells and colorectal adenocarcinoma (DLD-1) cells were treated with the synthesized water soluble phthalocyanine derivatives to understand the effect of the compounds both on colorectal and liver cancer cells. The compounds inhibited cell proliferation and displayed cytotoxic effect on these cancer cell lines however; the effect of the compounds on healthy control fibroblast cell line was comparatively lower. The compounds can be employed for cancer treatment as anticancer agents.

Keywords

Dendrimer , Anticancer activity; Liver cancer; Colorectal cancer

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