<i>Mentha longifolia</i> (L.) ssp. <i>longifolia</i> Essential Oil: Source of Natural Antioxidant and Antimutagen as Food Additive

Year 2018, Volume: 22 Issue: 1, 64 - 69, 16.04.2018

Rukiye Boran , Aysel Ugur

https://doi.org/10.19113/sdufbed.83327

Cited By: 1

Abstract

This research was performed to control the antioxidant activity, mutagenicity and antimutagenic effect of Mentha longifolia (L.) ssp. longifolia essential oil (EO), which is considered as a possible ingredient when producing healthy food. The antiradical activity was established using DPPH (2,2-diphenyl-1-picrylhydrazyl radical) and β-carotene/linoleic acid bleaching assays. The total phenolic content in the EO was evaluated by Folin Ciocalteau method (FCR).  Ames Salmonella/microsome mutagenicity assay was applied todetect possible mutagenic and antimutagenic behavior. Our observations reveal that the IC₅₀ value for DPPH radicals was 5.27 ± 0.13 mg/mL. The total antioxidant efficiency increased with an increase in the concentration of the EO, and IC₅₀ value 11.7 ± 0.21 mg/mL. The total of phenolics was 186 ± 8.9 mg/g gallic acid equivalent/EO. Also, any concentrations of the EO used did not show mutagenic action but exhibited strong antimutagenic effects at 10.0-4.0 µg/plate concentrations. This research proposes that because of the antioxidant and antimutagenic characteristics, the EO is very advantageous and significant to the company’s manufacturing food additives.

Keywords

Antimutagenic, Antioxidant; Essential oil; Food ingredient; Mentha longifolia

References

• [1] Alamed, J., Chaiyasit, W., McClements D. J., Decker E. A. 2009. Relationships between free radical scavenging and antioxidant activity in foods. Journal of Agricultural and Food Chemistry, 8, 2969-2976.
• [2] Kubow S. 1990. Toxicity of dietary lipid peroxidation products. Trends in Food Science & Technology, 1,67-71.
• [3] Lobo, V., Pati, A., Phatak, A., Chandra, N. 2010. Free radicals, antioxidants and functional foods: Impact on human health. Pharmacognosy Reviews, 4(8), 118-126.
• [4] Wanasundra, P. K. J. P. D., Shahidi, F. 2005. Antioxidants: Science, technology, and applications. In F. Shahidi editor, Bailey’s industrial oil, fat products 6th edition, N.J. Hoboken, John Wiley and Sons Inc. 431-489s.
• [5] Shahidi, F., Ambigaipalan, P. 2015. Phenolics and polyphenolics in foods, beverages and spices: Antioxidant activity and health effects – A review. Journal of Functional Foods, 18, 820-897.
• [6] Padmashree, A., Roopa, N., Semwal, A.D., Sharma, G.K., Agathian, G., Bawa, A.S. 2007. Star-anise (Illicium verum) and black caraway (Carum nigrum) as natural antioxidants. Food Chemistry, 104 (1), 59-66.
• [7] Negi, P.S. 2012. Plant extracts for the control of bacterial growth: Efficacy, stability and safety issues for food application. International Journal of Food Microbiology, 156, 7-17.
• [8] Bajpai, V.K., Baek, K.H., Kang, S.C. 2012. Control of Salmonella in foods by using essential oils: a review. Food Research International, 45, 722-734.
• [9] Teixeira, B., Marques, A., Ramos, C., Batista, I., Serrano, C., Matos, O., Neng, N.R., Nogueira, J.M.F., Saraiva, J.A., Nunes, M.L. 2012. European pennyroyal (Mentha pulegium) from Portugal: chemical composition of essential oil and antioxidant and antimicrobial properties of extracts and essential oil. Industrial Crops and Products, 36, 81-87.
• [10] Llana-Ruiz-Cabello, M., Pichardo, S., Maisanaba, S., Puerto, M., Prieto, A.I., Gutiérrez-Praena, D., Jos, A., Cameán, A.M.2015. In vitro toxicological evaluation of essential oils and their main compounds used in active food packaging: A review. Food and Chemical Toxicology, 81, 9-27.
• [11] Prakash, B., Kiran, S. 2016. Essential oils: a traditionally realized natural resource for food. Current Science, 110(10), 1890-1892.
• [12] Gulluce, M., Sahin, F., Sokmen, M., Ozer, H., Daferera, D., Sokmen, A., Polissiou, M., Adiguzel, A., Ozkan, H.2007. Antimicrobial and antioxidant properties of the essential oils and methanol extract from Menthalongifolia L. ssp. longifolia. Food Chemistry, 103, 1449-1456.
• [13] Mkaddem, M., Bouajila, J., Ennajar, M., Lebrihi, A., Mathieu, F. Romdhane, M. 2009. Chemical composition and antimicrobial and antioxidant activities of Mentha (longifolia L. and viridis) essential oils. Journal of Food Science, 74(7), 358-363.
• [14] Sarac, N., Ugur, A. 2009. The in vitro antimicrobial activities of the essential oils of some Lamiaceae species from Turkey. Journal of Medicinal Food, 12(4), 902-907.
• [15] Barros, A de S., Morais, S.M., Ferreiraa, P.A.T., Vieira, Í.P.G., Craveiroc, A.A., Fontenelle, R.O.S., de Menezes, J.E.S.A., da Silva, F.W.F.de Sousa,H. A. 2015. Chemical composition and functional properties of essential oils from Mentha species. Industrial Crops and Products, 76, 557-564.
• [16] Alsarar, A.S., Hussein, H.I., Abobakr, Y., Bayoumi, A. E., Alotaibi, M. T. 2014. Fumigant toxicity and antiacetylcholinesterase activity of Saudi Mentha longifolia and Lavandula dentata species against Callosobruchus maculatus (F.) (Coleoptera: Bruchidae). Turkish Journal of Entomology. 38, 11-18.
• [17] Jalilzadeh-Amin G., Maham M. 2015. Antidiarrheal activity and acute oral toxicity of Mentha longifolia L. essential oil. Avicenna Journal of Phytomedicine, 5(2), 128-1237.
• [18] Ebrahimabadi, A.H., Mazoochi, A., Kashi, F.J., Djafari-Bidgoli, Z., Batooli, H. 2010. Essential oil composition and antioxidant and antimicrobial properties of the aerial parts of Salvia eremophilaBoiss.from Iran. Food and Chemical Toxicology, 48(5), 1371-1376.
• [19] Rauter, A.P., Dias, C., Martins, A., Branco, I., Neng, N.R., Nogueira, J. M., Goulart, M., Silva, F.V.M., Justino, J., Trevitt, C., Waltho, J.P. 2012. Non-toxic Salvia sclareoides Brot. extracts as a source of functional food ingredients: Phenolic profile, antioxidant activity and prion binding properties. Food Chemistry, 132, 1930-1935.
• [20] Singleton, V.L., Orthofer, R., Lamuel-Raventos, R.M., 1999. Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin-Ciocalteu reagent. Methods in Enzymology, 299, 152-178.
• [21] Mortelmans, K., Zeiger, E. 2000. The Ames Salmonella/microsome mutagenicity assay. Mutation Research, 455, 29-60.
• [22] Maron, D., Ames, B. N. 1983. Revised methods for the Salmonella mutagenicity test. Mutation Research, 113, 173-215.
• [23] Taghvaei, M., Jafari, S. M. 2015. Application and stability of natural antioxidants in edible oils in order to substitute synthetic additives. Journal of Food Science and Technology, 52(3), 1272-1282.
• [24] Shahidi F., 1998. Indicators for evaluation of lipid oxidation and off-flavor development in food. Elsevier Amsterdam, The Netherlands, 55s.
• [25] Chahmi, N., Anissi, J., Jennan, S., Farah, A.,Sendide, K. El Hassoun, M., 2015. Antioxidant activities and total phenol content of Inula viscose extracts selected from three regions of Morocco. Asian Pacific Journal of Tropical Biomedicine, 5(3), 228-233.
• [26] Ramarathnam, N., Osawa, T., Namiki, M. Tashiro, T. 1986. Studies on the relationship between antioxidative activity of rice hull and germination ability of rice seeds. Journal of the Science of Food and Agriculture, 37, 719-726.
• [27] Al-Ali, K., Abdelrazik, M., Alghaithy, A., Diab, A., El-Beshbishy, H., Baghdadi H. 2014. Antimutagenic and anticancer activity of Al Madinah Alhasawy mint (Mentha longifolia) leaves extract. Pakistan Journal of Biological Sciences, 17, 1231-1236.
• [28] Baris O., Karadayi, M., Yanmis, D., Guvenalp, Z., Bal, T., Gulluce, M., 2011. Isolation of 3 flavonoids from Mentha longifolia (L.) Hudson subsp. Longifolia and determination of their genotoxic potentials by using the E. coli WP2 test system. Journal of Food Science, 76(9), 212-217.
• [29] Gulluce, M., Orhan, F., Adiguzel, A., Bal, T., Guvenalp, Z. Dermirezer, L. O. 2013. Determination of antimutagenic properties of apigenin-7-O-rutinoside, a flavonoid isolated from Mentha longifolia (L.) Huds. ssp. longifolia withyeast DEL assay. Toxicology and Industrial Health, 29(6), 534-540.
• [30] Ghahramanifar, M., Mirzaei, M., Mirzaei, A. Azemi, M. 2013. Cytotoxicity and antimutagenicity screening of 5 Iranian medicinal plants using Artemia urmiana and Ames Test. International Journal of Biology, Pharmacy and Allied Sciences, 2(3), 654-664.
• [31] Orhan, F., Barış, Ö., Yanmış, D., Bal, T., Güvenalp, Z., Güllüce, M. 2012. Isolation of some luteolin derivatives from Menthalongifolia (L.)Hudson subsp. longifolia and determination of their genotoxic potencies. Food Chemistry, 135(2), 764-769.