Non-sendromik dudak-damak yarıklı hastalarda 2.premolar ve 3.molar agenezisi

Year 2019, Volume: 6 Issue: 4, 189 - 194, 11.11.2019

İmran Güner Akgül Burcu Evlice

Abstract

Amaç: Bu çalışmanın amacı non-sendromik dudak-damak
yarıklı (DDY) hastalarda maksiller ve mandibular 2. premolar (2PM) ve 3. molar
(3M) agenezisinin prevalansını belirlemek ve agenezinin yarık bölgesi ile olan
ilişkisini saptamaktır.

Gereç ve Yöntemler: Bu retrospektif çalışmada 2009-2018 tarihleri arasında Çukurova
Üniversitesi Diş Hekimliği Fakültesi’ne başvuran 201 DDY’li hastanın
radyografik verileri ve hasta kayıtları incelendi. Asgari yaş sınırı 12 olarak
belirlendi ve hastalar farklı yaşlarda alınan en az 2 Ortopantomograf ve konik
ışınlı bilgisayarlı tomografi görüntüsünün olması ve herhangi bir
genetik/doğumsal sendromunun bulunmaması şartıyla çalışmaya dahil edildi.

Bulgular: 201 hastanın 85’i kadın, 116’sı erkekti. Hasta grubunda tek taraflı DDY
olan 139 hastanın 51’i sağ, 88’i sol tarafta yarık hattına sahipti. İki taraflı
DDY olan hasta sayısı 62 idi. Hastaların % 38.3’ünde 3M agenezisi, %32.3’ünde
2PM agenezisi saptandı. 109 hastada (% 54.2) en az bir diş eksikliği olduğu
görüldü. Tüm yarık tiplerinde maksillada (N=56), mandibuladan (N=6) veya her
iki çenede olduğundan (N=47) daha fazla eksik dişe rastlanmıştır (p < 0.05).

Sonuç: Elde ettiğimiz veriler DDY’li bireylerde 3M ve 2PM agenezisinin yaygın
olduğunu göstermektedir. DDY’nin lokalizasyonu ile etkilenen ve karşı çenedeki
eksik 2PM ve 3M arasında anlamlı bir ilişki bulunmamaktadır.

ANAHTAR KELİMELER

Diş agenezisi, dudak-damak yarığı,
non-sendromik

Keywords

Diş agenezisi, dudak-damak yarığı, non-sendromik

References

• 1. Menezes C, de Arruda JA, Silva LV, Monteiro JL, Caribé P, Álvares P, at al. Nonsyndromic cleft lip and/or palate: A multicenter study of the dental anomalies involved. J Clin Exp Dent. 2018 Aug 1;10(8):e746-e750. 2. Dixon MJ, Marazita ML, Beaty TH, Murray JC. Cleft lip and palate: understanding genetic and environmental influences. Nat Rev Genet. 2011;12:167-78. 3. Murray JC. Face facts: genes, environment, and clefts. Am J Hum Genet. 1995;57:227-32. 4. Harvold E. Observations on the development of the upper jaw by harelip and cleft. Odontologisk Tidskrift 1947;55:292-3. 5. Harvold E. Cleft lip and palate morphologic studies of the facial skeleton. Am J Orthod 1954;40:493-506. 6. Shapira Y, Lubit E, Kuftinec MM. Congenitally missing second premolars in cleft lip and cleft palate children. Am J Orthod Dentofacial Orthop. 1999 Apr;115(4):396-400. 7. Ranta R. Comparison of tooth formation in noncleft and cleft-affected children with and without hypodontia. J Dent Child 1982;49:197-9. 8. Ranta R. Hypodontia and delayed development of the second premolars in cleft palate children. Eur J Orthod 1983;5:145-8. 9. Olin WH. Dental anomalies in cleft lip and palate patients. Angle Orthod 1964;64:119-23. 10. Fernandez CCA, Pereira CVCA, Luiz RR, Faraco IM Jr, Marazita ML, Arnaudo M, at al. Third molar agenesis as a potential marker for craniofacial deformities. Arch Oral Biol. 2018 Apr;88:19-23. 11. Bartzela TN, Carels CE, Bronkhorst EM, Rønning E, Rizell S, Kuijpers-Jagtman AM. Tooth agenesis patterns in bilateral cleft lip and palate. Eur J Oral Sci. 2010;118:47–52. 12. Bartzela TN, Carels CEL, Bronkhorst EM, Kuijpers AM. Tooth agenesis patterns in unilateral cleft lip and palate in humans. Arch Oral Biol. 2013;58:596–602. 13. Celikoglu M, Kamak H. Patterns of third-molar agenesis in an orthodontic patient population with different skeletal malocclusions. Angle Orthod. 2012 Jan;82(1):165-9. 14. Massler M, Schour I, Poncher HG. Developmental pattern of the child as reflected in the calcification pattern of the teeth. Am J Dis Child 1941;62:33-67. 15. Barka G, Marathiotis K, Protogerakis M, Zafeiriadis A. Radiographic evaluation of third molar genesis in Greek orthodontic patients. Int J Gen Med. 2013 Sep 16;6:747-55. doi: 10.2147/IJGM.S42929. eCollection 2013. 16. Ravn J.J. Aplasia, supernumerary teeth and fused teeth in the primary dentition: an epidemiologic study. Scand. J. Dent Res. 1971;79:1–6. 17. Ranta R. Eruption of the premolars and canines and factors affecting in the unilateral cleft lip and palate cases. Proc Finn Dent Soc 1971;67:350-5. 18. Brown RV. The pattern and frequency of congenital absence of teeth [Master’sThesis]. State University of Iowa, June 1955. 19. Clayton JM. Congenital dental anomalies occurring in 3,557 children. J Dent Child 1956;23:206-8. 20. Valinoti JR Jr. The congenitally absent premolar problem. Angle Orthod 1958;28:36-46. 21. Bohn A. Dental anomalies in harelip and cleft palate. Acta Odontol Scand(Supp. 38) 1963;21:1-109. 22. Fishman LS. Factors related to tooth number, eruption time, and tooth position in cleft palate individuals. ASDC J Dent Child. 1970 Jul-Aug;37(4):303-6. 23. Kaur B, Sheikh S, Pallagatti S. Radiographic assessment of agenesis of third molars and para-radicular third molar radiolucencies in population of age group18–25 years old–a radiographic survey. Arch. Oral Res. 2012;8, 13–18. 24. Alam M.K, Hamza M.A, Khafiz M.A, Rahman S.A, Shaari R, Hassan A. Multi variate analysis of factors affecting presence and/or agenesis of third molar tooth. PLoS ONE. 2014;9(6):e101157. 25. Lynham A. Panoramic radiographic survey of hypodontia in Australian Defence Force recruits. Aust Dent J. 1990;35: 19-22. 26. Grahnen H. Hypodontia in the permanent dentition. A clinical and genetical investigation. Odont Revy. 1956;7: 1-100. 27. Kazanci F, Celikoglu M, Miloglu O, Oktay H. Third-molar agenesis among patients from the East Anatolian region of Turkey. J Contemp Dent Pract. 2010;11:E033-40. 28. Ranta R. The development of the permanent teeth in children with complete cleft lip and palate [Thesis]. Proc Finn Dent Soc (Supp. III) 1972;68:1-27.