Comparison of behavioral and hematological parameters before and after treatment in dogs with demodicosis

Year 2022, Volume: 93 Issue: 2, 99 - 104, 15.06.2022

Mustafa Koçkaya

https://doi.org/10.33188/vetheder.1006457

Abstract

This study aims to compare behavioral and hematological parameters of 12 dogs with demodectic mange infection before and after the treatment. Following the parasitological examination, an appropriate treatment protocol was planned for the dogs diagnosed with demodex canis. Blood samples were collected from the cephalic vein of the dogs and transferred into vacuum tubes containing EDTA before and after the treatment A complete blood count was performed for all dogs. Behavioral parameters before and after treatment were obtained with a video camera recording system. Compared to pre-treatment values, WBC, Mon (%), Neu (%), MCHC, and Eos (%) values were significantly lower after treatment while Lymph (%), RBC, Hb, MCV, MCH values were significantly higher after treatment, and the difference between the values was found to be statistically significant (P<0.01). Behavior parameters related to stress were detected in fewer dogs after the treatment compared to pre-treatment. This study provided valuable inputs to the literature as the concurrent examination of blood parameters and stress behavior was performed for the first time in dogs with demodectic mange infection.

Keywords

Blood parameters,, demodicosis,, dogs,, stress behaviors

Demodikozisli köpeklerde tedavi öncesi ve sonrasında davranış ve hematolojik parametrelerin karşılaştırılması

Abstract

Bu çalışmanın amacı demodektik uyuz enfeksiyonu olan 12 adet köpekte tedavi öncesi ve sonrasında hematolojik verilerle birlikte davranış parametrelerinin karşılaştırılmasıdır. Yapılan parazitolojik muayene sonucunda köpeklerde demodex canis tespit edildi ve uygun tedavi protokolü planlandı. Köpeklerden tedavi öncesinde ve tedavi tamamlandıktan sonra kan örnekleri tekniğine uygun olarak sefalik venden EDTA’lı vakumlu tüplere alındı ve tam kan sayımı yapıldı. Çalışmada tedavi öncesi ve tedavi sonrası davranış parametreleri video kamara kayıt sistemi ile elde edildi. WBC, Mon (%), Neu (%), MCHC ve Eos (%) değerlerinde tedavi sonrasında tedavi öncesine göre daha düşük, Lenf (%), RBC, Hb, MCV, MCH değerleri ise tedavi sonrasında tedavi öncesine göre daha yüksek tespit edildi ve değerler arasındaki fark istatistiksel olarak anlamlı bulundu (P<0.01). Her bir stres davranış parametresi tedavi sonrasında tedavi öncesine göre daha az sayıda köpekte gözlemlendi. Bu çalışma demodektik uyuz enfekiyonu olan köpeklerde kan ve stres davranış parametrelerinin birlikte incelenmesi yönüyle literatürde önemli bir yere sahip olacaktır.

Keywords

Demodikozis,, kan parametreleri,, köpekler,, stres davranışları

References

• Aydın ON (2002): Ağrı ve ağrı mekanizmalarına güncel bakış. ADÜ Tıp Fak Derg, 3(2), 37 – 48.
• Barcelos AM, Mills DS, Zulch H (2015): Clinical indicators of occult musculoskeletal pain in aggressive dogs. VetRecord, 176(18), 465-465. doi.org/10.1136/vr.102823
• Beerda B, Schilder MBH, Van Hoof JARAM, De Vries HW, Mol JA (2000): Behavioural and hormonal indicators of enduring environmental stress in dogs. Anim Welfare, 9, 49–62.
• Beigh SA, Soodan JS, Nazki S, Khan AM (2014): Oxidative stress, hematobiochemical parameters, trace elements and vitamins in dogs with zinc responsive dermatosis. Vet Arhiv, 84, 591-600.
• Broom DM, Johnson KG (1993): Stress and animal welfare. 1st ed. Springer Netherlands.
• Camps T, Amat M, Mariotti VM, Brech SL, Manteca X (2012): Pain-related aggression in dogs: 12 clinical cases. J Vet Beh Clin Appl Res,7(2), 99-102. doi.org/10.1016/j.jveb.2011.08.002
• Chávez F (2016): Case Report of Afoxolaner Treatment for Canine Demodicosis in Four Dogs Naturally Infected with Demodex canis. Inter J Appl Res Vet Med, 14, 123-127.
• Demirbaş YS, Emre B (2015): Stresin Köpeklerde Davranış Üzerine Etkileri. MAKÜ Sag Bil Enst Derg, 3(1), 34-42.
• Denerolle P, White SD, Taylor TS, Vandenabeele SI (2007): Organic diseases mimicking acral lick dermatitis in six dogs. J Am Anim Hosp Assoc, 43, 215–220.
• Fagundes AL, Hewison L, McPeake KJ, Zulch H, Mills DS (2018): Noise sensitivities in Dogs: An exploration of signs in Dogs with and without Musculoskeletal Pain Using Qualitative content Analysis. Front Vet Sci, 5, 17. https://doi.org/10.3389/fvets.2018.00017
• Gortel K (2006): Update on canine demodicosis. Vet Clin North Am Small Anim Pract, 36, 229–241.
• Gökalp G, Kırbaş A (2020): Köpek Demodikozisinde Genel Tanı ve Tedavi Yöntemleri. Bozok Vet Sci, 1(1), 51-60.
• Haleem AMM, Salib FA, Farag HS (2015): Evaluation of Haematological Parameters, Biochemical Parameters and Thyroxin Level in Dogs with Generalized Demodicosis. Global Veterinaria, 15(1), 133-136. DOI: 10.5829/idosi.gv.2015.15.01.96125
• Koçkaya M, Şireli M (2015): Comparison of behavioral and physiological responses of Kangal dogs in different livestock flocks. Ankara Üniv Vet Fak Derg, 62, 261-267. DOI:10.1501/Vetfak_0000002690
• Koçkaya M, Özşensoy Y, İnsal B (2019): Comparisons of some physiological and stress behaviour parameters of Kangal shepherd dogs with and without ankyloglossia in different environmental tempetarures. Turk J Vet Anim Sci, 43(3), 314-322.
• Lindsay SR (2001): Handbook of applied dog behavior and training. 1st ed. Vol. 2, Etiology and assessment of behavior problems. Iowa State University Press, Ames, Iowa.
• Maden M, Er C, Kav K, Özdemir Ö (2012): İngiliz Pointer Irkı Bir Köpekte Demodex Canis Kökenli Atipik Dermatitis Olgusunun Başarılı Sağaltımı. Kafkas Univ Vet Fak Derg, 18(6), 1073-1077. DOI:10.9775/kvfd.2012.7158.
• Martin P, Bateson P (1993): Measuring behaviour. An introductory guide. 2nd ed. Aufl., Cambridge University Press, Cambridge, Melbourne, New York.
• Mills DS, Bedard ID, Gruen M, Klinck MP, McPeake KJ, Barcelos AM, Hewison L, Haevermaet HV, Denenberg S, Hauser H, Koch C, Ballantyne K, Wilson C, Mathkari CV, Pounder J, Garcia E, Darder P, Fatjo J, Levine E (2020): Pain and Problem Behavior in Cats and Dogs. Animals, 10(2), 318. doi.org/10.3390/ani10020318
• Moberg GP (1987): A model for assessing the impact of behavioral stress on domestic animals. J Anim Sci, 65, 1228-1235.
• Paterson TE, Halliwell RE, Fields PJ, Louw ML, Louw JP, Ball GS, Pinckney RD, McKibben JS (2009): Treatment of canine-generalized demodicosis: a blind, randomized clinical trial comparing the efficacy of Advocate® (Bayer Animal Health) with ivermectin. Vet Dermatol, 20, 447–455.
• Reddy BS, Kumari KN, Sivajothi S (2015): Haemato-biochemical findings and thyroxin levels in canine demodicosis. Comp Clin Pathol, 24, 287–290. DOI 10.1007/s00580-014-1893-y
• Sakina A, Mandial RK, Mudasir Q (2012): Haematobiochemical changes in canine demodecosis. Vet Scan, 7, 75-78.
• Sharma P, Wadhwa DR, Katoch A, Sharma A (2018): Epidemiological, clinico-haematological and therapeutic studies on canine demodicosis. J Dairy Vet Anim Res, 7, 109‒113. DOI: 10.15406/jdvar.2018.07.00200
• SPSS (2013): IBM SPSS Statistics for Windows, Version 22.0. Armonk, NY:IBM Corp.
• Şentürk Aİ (2018): Ağrı Değerlendirilmesi: Tipleri ve Mekanizmaları. Med Res Rep, 1(3), 78-81.
• Toates F (2004): Cognition, motivation, emotion and action: A dynamic and vulnerable interdependence. Appl Anim Behav Sci, 86, 173–204.