Is there a relationship between vascular flow parameters of carotid arterial system and trigeminal neuralgia?

Yıl 2024, Cilt: 10 Sayı: 2, 148 - 154, 30.08.2024

Ela Kaplan , Mehtap Koparal

https://doi.org/10.30569/adiyamansaglik.1506395

Öz

Aim: To investigate the flow velocity values and resistance parameters determined by carotid artery doppler ultrasonography (DUS) examination in patients with trigeminal neuralgia (TN).
Materials and Methods: 79 patients diagnosed with TN and who underwent carotid DUS were included in the study. Spectral examination results were recorded for the TN side and the healthy side.
Results: Peak systolic velocity (PSV) internal carotid artery (ICA), resistive index (RI) (ICA) and PSV (ICA)/PSV external carotid (ECA) values in patients were relatively higher in arterial structures on the TN clinical side compared to the healthy side. RI (ICA)/RI common carotid artery (CCA) value was also high in arterial structures on the TN diagnosed side.
Conclusion: It was shown that especially ICA flow velocity and vascular resistance parameters increased in the carotid arterial system on the TN side. These findings indicate that flow parameters in the carotid artery system may also be effective in TN pathophysiology.

Anahtar Kelimeler

Trigeminal neuralgia, Carotid artery, Doppler ultrasound imaging

Etik Beyan

Ethics committee approval for this study was obtained from the regional hospital ethics committee Medicine Non-invasive Clinical Research Ethics Committee (Date: 16/02/2022, Decision No: 2022/2-4). All procedures were utilized in accordance with the Declaration of Helsinki.

Destekleyen Kurum

None

Teşekkür

Authors would like to thank Assoc. Prof. Dr. Erman Altunışık for his support during this study.

Karotis arteryel sistem vasküler akım parametreleri ile trigeminal nevralji arasında ilişki var mıdır?

Öz

Amaç: Trigeminal nevralji (TN) hastalarında karotis arter doppler ultrasonografi (DUS) incelemesi ile saptanan akım hızı değerleri ve direnç parametrelerini araştırmak.
Gereç ve Yöntem: TN tanısı almış 79 hastaya karotis DUS yapıldı. Spektral inceleme sonuçları TN'li bölge ve sağlam bölge için kaydedildi.
Bulgular: Hastalarda peak sistolik hız (PSV) internal karotis arter (ICA), rezitif indeks (RI) (ICA) ve PSV (ICA)/PSV eksternal karotis (ECA) değerleri TN kliniği olan taraftaki arteriyel yapılarda sağlıklı tarafa göre nispeten yüksekti. RI (ICA)/RI common carotis arter (CCA) değeri de TN tanısı olan taraftaki arteriyel yapılarda yüksekti.
Sonuç: Özellikle ICA akım hızı ve vasküler direnç parametrelerinin TN tarafında karotis arteriyel sistemde arttığı gösterildi. Bu bulgular karotid arter sistemindeki akış parametrelerinin TN patofizyolojisinde etkili olabileceğini göstermektedir.

Anahtar Kelimeler

Trigeminal nevralji, Karotis arteri, Doppler ultrason görüntüleme

Kaynakça

• Gambeta E, Chichorro JG, Zamponi GW. Trigeminal neuralgia: An overview from pathophysiology to pharmacological treatments. Mol Pain. 2020;16:1744806920901890. doi:10.1177/1744806920901890
• Jones MR, Urits I, Ehrhardt KP, et al. A Comprehensive Review of Trigeminal Neuralgia. Curr Pain Headache Rep. 2019;23(10):74. doi:10.1007/s11916-019-0810-0
• Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition. Cephalalgia. 2018;38(1):1-211. doi:10.1177/0333102417738202
• Lambru G, Zakrzewska J, Matharu M. Trigeminal neuralgia: a practical guide. Pract Neurol. 2021;21(5):392-402. doi:10.1136/practneurol-2020-002782
• Bendtsen L, Zakrzewska JM, Heinskou TB, et al. Advances in diagnosis, classification, pathophysiology, and management of trigeminal neuralgia. Lancet Neurol. 2020;19(9):784-796. doi:10.1016/S1474-4422(20)30233-7
• Maarbjerg S, Benoliel R. The changing face of trigeminal neuralgia-A narrative review. Headache. 2021;61(6):817-837. doi:10.1111/head.14144
• Cruccu G, Gronseth G, Alksne J, et al. AAN-EFNS guidelines on trigeminal neuralgia management. Eur J Neurol. 2008;15(10):1013-1028. doi:10.1111/j.1468-1331.2008.02185.x
• Gronseth G, Cruccu G, Alksne J, et al. Practice parameter: the diagnostic evaluation and treatment of trigeminal neuralgia (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the European Federation of Neurological Societies. Neurology. 2008;71(15):1183-1190.
• Cruccu G, Finnerup NB, Jensen TS, et al. Trigeminal neuralgia: New classification and diagnostic grading for practice and research. Neurology. 2016;87(2):220-228. doi:10.1212/WNL.0000000000002840
• Sarsam Z, Garcia-Fiñana M, Nurmikko TJ, Varma TR, Eldridge P. The long-term outcome of microvascular decompression for trigeminal neuralgia. Br J Neurosurg. 2010;24(1):18-25. doi:10.3109/02688690903370289.
• Sindou M, Leston J, Howeidy T, Decullier E, Chapuis F. Micro-vascular decompression for primary Trigeminal Neuralgia (typical or atypical). Long-term effectiveness on pain; prospective study with survival analysis in a consecutive series of 362 patients. Acta Neurochir (Wien). 2006;148(12):1235-1245. doi:10.1007/s00701-006-0809-2
• Pignoli P, Tremoli E, Poli A, Oreste P, Paoletti R. Intimal plus medial thickness of the arterial wall: a direct measurement with ultrasound imaging. Circulation. 1986;74(6):1399-1406. doi:10.1161/01.cir.74.6.1399
• Wong M, Edelstein J, Wollman J, Bond MG. Ultrasonic-pathological comparison of the human arterial wall. Verification of intima-media thickness. Arterioscler Thromb. 1993;13(4):482-486. doi:10.1161/01.atv.13.4.482
• Leal PR, Barbier C, Hermier M, Souza MA, Cristino-Filho G, Sindou M. Atrophic changes in the trigeminal nerves of patients with trigeminal neuralgia due to neurovascular compression and their association with the severity of compression and clinical outcomes. J Neurosurg. 2014;120(6):1484-1495. doi:10.3171/2014.2.JNS131288
• Leal PRL, Roch JA, Hermier M, Souza MAN, Cristino-Filho G, Sindou M. Structural abnormalities of the trigeminal root revealed by diffusion tensor imaging in patients with trigeminal neuralgia caused by neurovascular compression: a prospective, double-blind, controlled study. Pain. 2011;152(10):2357-2364. doi:10.1016/j.pain.2011.06.029
• Shimizu M, Imai H, Kagoshima K, Umezawa E, Shimizu T, Yoshimoto Y. Detection of compression vessels in trigeminal neuralgia by surface-rendering three-dimensional reconstruction of 1.5- and 3.0-T magnetic resonance imaging. World Neurosurg. 2013;80(3-4):378-385. doi:10.1016/j.wneu.2012.05.030.
• DeSouza DD, Davis KD, Hodaie M. Reversal of insular and microstructural nerve abnormalities following effective surgical treatment for trigeminal neuralgia. Pain. 2015;156(6):1112-1123. doi:10.1097/j.pain.0000000000000156
• Bots ML, Hoes AW, Koudstaal PJ, Hofman A, Grobbee DE. Common carotid intima-media thickness and risk of stroke and myocardial infarction: the Rotterdam Study. Circulation. 1997;96(5):1432-1437. doi:10.1161/01.cir.96.5.1432
• Grobbee DE, Bots ML. Carotid artery intima-media thickness as an indicator of generalized atherosclerosis. J Intern Med. 1994;236(5):567-573. doi:10.1111/j.1365-2796.1994.tb00847.x
• Nishiyama Y, Katsumata T, Otori T, Katayama Y. Carotid hemodynamic parameters are useful for discriminating between atherothrombotic infarction and lacunar infarction. J Stroke Cerebrovasc Dis. 2010;19(6):441-449. doi:10.1016/j.jstrokecerebrovasdis.2009.08.005