Evaluation of incidental prostate cancer in patients who underwent radical cystectomy and its effect on survival

Yıl 2024, Cilt: 10 Sayı: 3, 211 - 217, 31.12.2024

Abuzer Öztürk , İsmail Emre Ergin , Hüseyin Saygın , Aydemir Asdemir

https://doi.org/10.30569/adiyamansaglik.1513534

Öz

Aim: Our study aimed to investigate the incidence of incidental prostate adenocarcinoma, its histopathological results and its effect on survival in patients who underwent radical cystectomy due to bladder tumor.
Materials and Methods: Patients who underwent radical cystectomy with a diagnosis of bladder tumor in our clinic in the last ten years and who had no preoperative suspicion or diagnosis of prostate cancer were included in the study. Patients were divided into two groups those with and without incidentally prostate cancer. Both groups were compared in terms of age, PSA value, histopathological features and overall survival.
Results: 15 (22.6%) of 79 patients who underwent radical cystectomy and were followed up for an average of 62 months were incidentally diagnosed with prostate adenocarcinoma. There was a significant difference between mean PSA value in patients with prostate cancer and the group without prostate cancer (p=0.004). When we evaluated it in terms of five-year overall survival, no significant difference was found between the two groups.
Conclusion: Although incidental prostate cancer does not seem to affect survival, it is necessary to follow up regularly in the presence of prostate cancer and be more careful, especially in the presence of locally advanced prostate cancer.

Anahtar Kelimeler

Cystectomy, Survival, Incidental prostate adenocarcinoma, Urotelial bladder carcinoma

Etik Beyan

The study protocol received scrutiny and approval from the Sivas Cumhuriyet University Clinical Research Ethics Committee (decision no: 2023-07/02, date: 20.07.2023). Our study was conducted in accordance with the principles of the Declaration of Helsinki. Informed consent form were obtained from all patients.

Destekleyen Kurum

No person/organization is supporting this study financially.

Radikal sistektomi uygulanan hastalarda insidental prostat kanserinin değerlendirilmesi ve sağkalım üzerindeki etkisi

Öz

Amaç: Çalışmamızda mesane tümörü nedeniyle radikal sistektomi uygulanan hastalarda rastlantısal prostat adenokarsinomu görülme sıklığı, histopatolojik sonuçları ve sağ kalım üzerine etkisinin araştırılması amaçlandı.
Gereç ve Yöntem: Çalışmaya son 10 yıl içinde kliniğimizde mesane tümörü tanısıyla radikal sistektomi yapılan, ameliyat öncesi prostat kanseri şüphesi veya tanısı olmayan hastalar dahil edildi. Hastalar rastlantısal prostat kanseri saptanan ve saptanmayan grup olarak ikiye ayrıldı. Her iki grup yaş, PSA değeri, histopatolojik özellikler ve genel sağkalım açısından karşılaştırıldı.
Bulgular: Radikal sistektomi uygulanan ve ortalama 62 ay takip edilen 79 hastanın 15'ine (%22,6) insidental prostat adenokarsinomu tanısı konuldu. Prostat kanserli hastalar ile prostat kanseri olmayan grup arasında ortalama PSA değeri arasında anlamlı fark vardı (p=0,004). Beş yıllık genel sağkalım açısından değerlendirdiğimizde iki grup arasında anlamlı fark bulunamadı.
Sonuç: İnsidental prostat kanseri sağ kalımı etkilemiyor gibi görünse de prostat kanseri varlığında düzenli takip yapmak ve özellikle lokal ileri prostat kanseri varlığında daha dikkatli olmak gerekir.

Anahtar Kelimeler

Sistektomi, Sağkalım, Rastlantısal prostat adenokarsinomu, Ürotelyal mesane karsinomu

Etik Beyan

The study protocol received scrutiny and approval from the Sivas Cumhuriyet University Clinical Research Ethics Committee (decision no: 2023-07/02, date: 20.07.2023). Our study was conducted in accordance with the principles of the Declaration of Helsinki. Informed consent form were obtained from all patients.

Destekleyen Kurum

No person/organization is supporting this study financially.

Kaynakça

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