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ADULTERATION OF URINE DRUG TESTING: CASE REPORT AND REVIEW

Cilt: 27 Sayı: 3 31 Aralık 2013
  • Faruk Aşıcıoğlu
  • Zeynep Orhan
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ADULTERATION OF URINE DRUG TESTING: CASE REPORT AND REVIEW

Öz

Drug tests are conducted for individuals having suspected intoxication, having suspected drug use, involving in an accident, being in probation control; applicants during recruitment and prisoners. However, the validity of these tests depend on the urine sample’s being uninterferenced. Because, illicit drug users add easily available common foreign substances(adulterants) into the urine to deceive these tests. Adulterants are classified into two categories. The first category includes classic adulterants comprising of some household chemicals such as chlorine bleach, white vinegar, glutaraldehyde, liquid drain cleaner, sodium nitrite, pyridinium chlorochromate. The second category includes commercial products which can be purchased from certain specialty stores or via internet. Dilution of urine by means of excess water intake is the most basic method used for adulteration. The case we present tried to falsify the result two times by drinking water and once by giving the urine of a different person for the analysis. Adulterant use can be disclosed by presumptive tests such as specific gravity, pH, temperature, creatinine, nitrite, glutaraldehyde levels which are useful for determining whether the urine sample is interferenced or not. Urine dilution in our case is disclosed by the abnormal creatinine concentration of less than 20 mg/dL. This case was presented to draw attention for adulterant use which is not common and well known by scientists in Turkey.

Anahtar Kelimeler

Kaynakça

  1. WongR. The effect of adulterants on urine screen for drugsof abuse: Detection by an on-site dipstick device. Am Clin Lab 2002;21(1)37-9.
  2. Mikkelsen SL, Ash KO. Adulterants causing false negative in illicit drug test. Clin Chem 1988;34(11):2333-36.
  3. Denetimli Serbestlik ve Yardım Merkezleri İle Koruma Kurulları Yönetmeliği (18/04/2007 tarih, 2007/26497 sayılı Resmi Gazete).
  4. Dasgupta A, Wahed A, Wells A. Rapid spot tests for detecting the presence of adulterants in urine specimens submitted for drug testing. Am J Clin Pathol 2002;117(2):325-29.
  5. Burrows DL, Nicolaides A, Rice PJ, Dufforc M, Johnson DA, Ferslew KE. Papain: a novel urine adulterant. J Anal Toxicol 2005;29(5):275-95.
  6. Warner A. Interference of household chemicals in immunoassay methods for drugs of abuse. Clin Chem 1989;35(4):648-51
  7. Baiker C, Serrano L, Lindner B. Hypochlorite adulteration of urine causing decreased concentration of delta 9-THC-COOH by GC/MS. J Anal Toxicol 1994;18(2):101-3.
  8. U.S.Dept. of Health and Human Services. Mandatory Guidelines for Federal Workplace Drug Testing Programs: Final Guidelines Notice. Fed Reg 1988;53:11969-89

Ayrıntılar

Birincil Dil

İngilizce

Konular

Adli Biyoloji

Bölüm

Derleme

Yazarlar

Faruk Aşıcıoğlu Bu kişi benim
Türkiye

Zeynep Orhan Bu kişi benim
Türkiye

Yayımlanma Tarihi

31 Aralık 2013

Gönderilme Tarihi

3 Temmuz 2013

Kabul Tarihi

5 Eylül 2013

Yayımlandığı Sayı

Yıl 2013 Cilt: 27 Sayı: 3

Kaynak Göster

APA
Aşıcıoğlu, F., & Orhan, Z. (2013). ADULTERATION OF URINE DRUG TESTING: CASE REPORT AND REVIEW. Adli Tıp Dergisi, 27(3), 103-106. https://izlik.org/JA76FA93LD
AMA
1.Aşıcıoğlu F, Orhan Z. ADULTERATION OF URINE DRUG TESTING: CASE REPORT AND REVIEW. ATD. 2013;27(3):103-106. https://izlik.org/JA76FA93LD
Chicago
Aşıcıoğlu, Faruk, ve Zeynep Orhan. 2013. “ADULTERATION OF URINE DRUG TESTING: CASE REPORT AND REVIEW”. Adli Tıp Dergisi 27 (3): 103-6. https://izlik.org/JA76FA93LD.
EndNote
Aşıcıoğlu F, Orhan Z (01 Aralık 2013) ADULTERATION OF URINE DRUG TESTING: CASE REPORT AND REVIEW. Adli Tıp Dergisi 27 3 103–106.
IEEE
[1]F. Aşıcıoğlu ve Z. Orhan, “ADULTERATION OF URINE DRUG TESTING: CASE REPORT AND REVIEW”, ATD, c. 27, sy 3, ss. 103–106, Ara. 2013, [çevrimiçi]. Erişim adresi: https://izlik.org/JA76FA93LD
ISNAD
Aşıcıoğlu, Faruk - Orhan, Zeynep. “ADULTERATION OF URINE DRUG TESTING: CASE REPORT AND REVIEW”. Adli Tıp Dergisi 27/3 (01 Aralık 2013): 103-106. https://izlik.org/JA76FA93LD.
JAMA
1.Aşıcıoğlu F, Orhan Z. ADULTERATION OF URINE DRUG TESTING: CASE REPORT AND REVIEW. ATD. 2013;27:103–106.
MLA
Aşıcıoğlu, Faruk, ve Zeynep Orhan. “ADULTERATION OF URINE DRUG TESTING: CASE REPORT AND REVIEW”. Adli Tıp Dergisi, c. 27, sy 3, Aralık 2013, ss. 103-6, https://izlik.org/JA76FA93LD.
Vancouver
1.Faruk Aşıcıoğlu, Zeynep Orhan. ADULTERATION OF URINE DRUG TESTING: CASE REPORT AND REVIEW. ATD [Internet]. 01 Aralık 2013;27(3):103-6. Erişim adresi: https://izlik.org/JA76FA93LD

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