EN
ADULTERATION OF URINE DRUG TESTING: CASE REPORT AND REVIEW
Öz
Drug tests are conducted for individuals having suspected intoxication, having suspected drug
use, involving in an accident,
being in probation control; applicants during recruitment and
prisoners. However, the validity of
these tests depend on the urine
sample’s being uninterferenced.
Because, illicit drug users add
easily available common foreign substances(adulterants) into
the urine to deceive these tests.
Adulterants are classified into
two categories. The first category includes classic adulterants
comprising of some household
chemicals such as chlorine bleach, white vinegar, glutaraldehyde, liquid drain cleaner, sodium
nitrite, pyridinium chlorochromate. The second category includes
commercial products which can
be purchased from certain specialty stores or via internet.
Dilution of urine by means of
excess water intake is the most
basic method used for adulteration. The case we present
tried to falsify the result two
times by drinking water and
once by giving the urine of a different person for the analysis.
Adulterant use can be disclosed by presumptive tests such
as specific gravity, pH, temperature, creatinine, nitrite, glutaraldehyde levels which are
useful for determining whether
the urine sample is interferenced or not. Urine dilution in our
case is disclosed by the abnormal creatinine concentration of
less than 20 mg/dL. This case
was presented to draw attention for adulterant use which is
not common and well known by
scientists in Turkey.
Anahtar Kelimeler
Kaynakça
- WongR. The effect of adulterants on urine screen for drugsof abuse: Detection by an on-site dipstick device. Am Clin Lab 2002;21(1)37-9.
- Mikkelsen SL, Ash KO. Adulterants causing false negative in illicit drug test. Clin Chem 1988;34(11):2333-36.
- Denetimli Serbestlik ve Yardım Merkezleri İle Koruma Kurulları Yönetmeliği (18/04/2007 tarih, 2007/26497 sayılı Resmi Gazete).
- Dasgupta A, Wahed A, Wells A. Rapid spot tests for detecting the presence of adulterants in urine specimens submitted for drug testing. Am J Clin Pathol 2002;117(2):325-29.
- Burrows DL, Nicolaides A, Rice PJ, Dufforc M, Johnson DA, Ferslew KE. Papain: a novel urine adulterant. J Anal Toxicol 2005;29(5):275-95.
- Warner A. Interference of household chemicals in immunoassay methods for drugs of abuse. Clin Chem 1989;35(4):648-51
- Baiker C, Serrano L, Lindner B. Hypochlorite adulteration of urine causing decreased concentration of delta 9-THC-COOH by GC/MS. J Anal Toxicol 1994;18(2):101-3.
- U.S.Dept. of Health and Human Services. Mandatory Guidelines for Federal Workplace Drug Testing Programs: Final Guidelines Notice. Fed Reg 1988;53:11969-89
Ayrıntılar
Birincil Dil
İngilizce
Konular
Adli Biyoloji
Bölüm
Derleme
Yayımlanma Tarihi
31 Aralık 2013
Gönderilme Tarihi
3 Temmuz 2013
Kabul Tarihi
5 Eylül 2013
Yayımlandığı Sayı
Yıl 2013 Cilt: 27 Sayı: 3
APA
Aşıcıoğlu, F., & Orhan, Z. (2013). ADULTERATION OF URINE DRUG TESTING: CASE REPORT AND REVIEW. Adli Tıp Dergisi, 27(3), 103-106. https://izlik.org/JA76FA93LD
AMA
1.Aşıcıoğlu F, Orhan Z. ADULTERATION OF URINE DRUG TESTING: CASE REPORT AND REVIEW. ATD. 2013;27(3):103-106. https://izlik.org/JA76FA93LD
Chicago
Aşıcıoğlu, Faruk, ve Zeynep Orhan. 2013. “ADULTERATION OF URINE DRUG TESTING: CASE REPORT AND REVIEW”. Adli Tıp Dergisi 27 (3): 103-6. https://izlik.org/JA76FA93LD.
EndNote
Aşıcıoğlu F, Orhan Z (01 Aralık 2013) ADULTERATION OF URINE DRUG TESTING: CASE REPORT AND REVIEW. Adli Tıp Dergisi 27 3 103–106.
IEEE
[1]F. Aşıcıoğlu ve Z. Orhan, “ADULTERATION OF URINE DRUG TESTING: CASE REPORT AND REVIEW”, ATD, c. 27, sy 3, ss. 103–106, Ara. 2013, [çevrimiçi]. Erişim adresi: https://izlik.org/JA76FA93LD
ISNAD
Aşıcıoğlu, Faruk - Orhan, Zeynep. “ADULTERATION OF URINE DRUG TESTING: CASE REPORT AND REVIEW”. Adli Tıp Dergisi 27/3 (01 Aralık 2013): 103-106. https://izlik.org/JA76FA93LD.
JAMA
1.Aşıcıoğlu F, Orhan Z. ADULTERATION OF URINE DRUG TESTING: CASE REPORT AND REVIEW. ATD. 2013;27:103–106.
MLA
Aşıcıoğlu, Faruk, ve Zeynep Orhan. “ADULTERATION OF URINE DRUG TESTING: CASE REPORT AND REVIEW”. Adli Tıp Dergisi, c. 27, sy 3, Aralık 2013, ss. 103-6, https://izlik.org/JA76FA93LD.
Vancouver
1.Faruk Aşıcıoğlu, Zeynep Orhan. ADULTERATION OF URINE DRUG TESTING: CASE REPORT AND REVIEW. ATD [Internet]. 01 Aralık 2013;27(3):103-6. Erişim adresi: https://izlik.org/JA76FA93LD
