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Tıbbi Bitkilerin Doku Şartlandırıcılara İlave Edilmesiyle Antibakteriyel ve Antifungal Etkinlik Sağlanabilir Mi?

Yıl 2023, , 165 - 174, 18.01.2023
https://doi.org/10.54617/adoklinikbilimler.1128243

Öz

Bu çalışmanın amacı, antienflamatuar, antibakteriyel ve antioksidan özelliklerinden faydalanmak amacıyla tıbbi bitkilerin doku şartlandırıcılara ilave edilmesini konu alan literatürlerin taranması ve başarılı bir tedavi için kanıta dayalı bilgi verilmesidir. Bu çalışmada, diş hekimliğinde bitkilerin antimikrobiyal ve antifungal özelliklerinin değerlendirilmesi ve doku şartlandırıcılara ilave edildiğinde elde edilen sonuçların irdelenmesi amacıyla PubMed aracılığı ile Medline veri tabanında literatür taraması yapılmıştır. Araştırılan makaleler sonucunda, bitkilerin doku şartlandırıcılara ilavesinin diş hekimliğinde alternatif bir destekleyici tedavi seçeneği olabileceği tespit edilmiştir. Bununla birlikte, yapılan tüm değerlendirmelerden sonra, bu uygulamaların uzun dönem başarısı ve klinik kullanımları açısından daha ileri çalışmalara ihtiyaç duyulmaktadır.

Destekleyen Kurum

Yok

Proje Numarası

Yok

Teşekkür

Yok

Kaynakça

  • Referans1. Pattanaik S, Vikas B, Pattanaik B, Sahu S, Lodam S. Denture stomatitis: a literature review. J Indian Acad Oral Med Radiol 2010;22:136-40.
  • Referans2. Zissis A, Yannikakis S, Harrison A. Comparison of denture stomatitis prevalence in 2 population groups. Int J Prosthodont 2006;19:621-5.
  • Referans3. Silva MM, Mima EG, Colombo AL, Sanitá PV, Jorge JH, Massucato EM, et al. Comparison of denture microwave disinfection and conventional antifungal therapy in the treatment of denture stomatitis: a randomized clinical study. Oral Surg Oral Med Oral Pathol Oral Radiol 2012;114:469-79.
  • Referans4. Mima EG, Vergani CE, Machado AL, Massucato EM, Colombo AL, Bagnato VS, et al. Comparison of Photodynamic Therapy versus conventional antifungal therapy for the treatment of denture stomatitis: a randomized clinical trial. Clin Microbiol Infect 2012;18:E380-8.
  • Referans5. Darwazeh AM-G, Al-Refai S, Al-Mojaiwel S. Isolation of Candida species from the oral cavity and fingertips of complete denture wearers. J Prosthet Dent 2001;86:420-3.
  • Referans6. Barbeau J, Séguin J, Goulet JP, de Koninck L, Avon SL, Lalonde B, et al. Reassessing the presence of Candida albicans in denture-related stomatitis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003;95:51-9.
  • Referans7. Yamamoto D, Shinohara Y, Nagadome H, Terada Y. Development of tissue conditioner capable of binding with anti-microbial protein lactoferrin. J Prosthodont Res 2009;53:136-41.
  • Referans8. Amin WM, Al-Ali MH, Salim NA, Al-Tarawneh SK. A new form of intraoral delivery of antifungal drugs for the treatment of denture-induced oral candidosis. Eur J Dent 2009;3:257-66.
  • Referans9. Buggapati L. Herbs in dentistry. Int J Pharm Sci Invent 2016;5:7-12.
  • Referans10. Rotblatt M, Ziment I, eds. Evidence-Based Herbal Medicine. Philadelphia: Hanley & Belfus Inc, 2002.
  • Referans11. Taheri JB, Azimi S, Rafieian N, Zanjani HA. Herbs in dentistry. International Dental Journal. 2011;61:287-96.
  • Referans12. Bonou J, Baba-Moussa F, Adéoti Z, Ahouandjinou H, Dougnon V, Dossa D, et al. Antimicrobial activity of essential oils of Lippia multiflora, Eugenia caryophyllata, Mentha piperita and Zingiber officinale on five oral-dental microorganisms. J Pharmacogn Phytochem 2016;5:271-6.
  • Referans13. Krishnamoorthy G, Narayana AI, Peralam PY, Balkrishanan D. To study the effect of Cocos nucifera oil when incorporated into tissue conditioner on its tensile strength and antifungal activity: An in vitro study. J Indian Prosthodont Soc 2019;19:225-32.
  • Referans14. Choonharuangdej S, Amornvit P, Srithavaj T, Alam MK. In vitro anti-candida effect of Thai herbs supplemented in tissue conditioner. Int Med J 2014;21:331-4.
  • Referans15. Srivatstava A, Ginjupalli K, Perampalli NU, Bhat N, Ballal M. Evaluation of the properties of a tissue conditioner containing origanum oil as an antifungal additive. J Prosthet Dent 2013;110:313-9.
  • Referans16. Carretto CFP, Navas EAFA, Paradella TC, Oliveira LD, Junqueira JC, Jorge AOC. Efeitos do chá de tomilho sobre a aderência in vitro de Streptococcus mutans ao esmalte dentário e Candida albicans à resina acrílica. Rev odontol UNESP 2013;36:281-6.
  • Referans17. Gonçalves G, Bottaro M, Nilson A. Effect of the Thymus vulgaris essential oil on the growth of Streptococcus mutans. J Appl Pharm Sci 2011;32:375-80.
  • Referans18. Hosseinzadeh S, Jafarikukhdan A, Hosseini A, Armand R. The application of medicinal plants in traditional and modern medicine: a review of Thymus vulgaris. Int J Clin Med 2015;6:635-42.
  • Referans19. Newman DJ, Cragg GM. Natural products as sources of new drugs over the last 25 years. J Nat Prod 2007;70:461-77.
  • Referans20. Al-Timimi EA, Mohammed AC. Effect of thymus vulgaris extract on streptococci and mutans streptococci, in comparison to chlorhexidine gluconate (in vivo study). J Baghdad Coll Dent 2012;24:116-21.
  • Referans21. Fani M, Kohanteb J. In vitro antimicrobial activity of Thymus vulgaris essential oil against major oral pathogens. Evid Based Complementary Altern Med 2017;22(4):660-666.
  • Referans22. Kavianirad F, Bahador N, Naseri N, Baherimoghadam T, Safaeian R. The antifungal effect of thymus vulgaris on isolated candida albicans from the surface of removable orthodontic appliances. Herb Med J 2019;4(2):55-64.
  • Referans23. Rasooli I, Shayegh S, Taghizadeh M, Astaneh SA. Rosemarinus officinalis and Thymus eriocalyx essential oils combat in vitro and in vivo dental biofilm formation. Pharmacogn Mag 2008;4:65-72.
  • Referans24. Hassan A, Hassan A. In vitro antimicrobial activity of thymus vulgaris, origanum vulgare and rosmarinus officinalis against dental caries pathogens. Ibn al-Haitham J Pure Appl Sci 2017;25:33-9.
  • Referans25. Singh R, Shushni MA, Belkheir A. Antibacterial and antioxidant activities of Mentha piperita L. Arab J Chem 2015;8:322-8.
  • Referans26. Shayegh S, Rasooli I, Taghizadeh M, Alipoor Astaneh SD. Phytotherapeutic inhibition of supragingival dental plaque. Nat Prod Res 2008;22:428-39.
  • Referans27. Rasooli I, Shayegh S, Taghizadeh M, Astaneh SDA. Phytotherapeutic prevention of dental biofilm formation. Phytother Res 2008;22:1162-7.
  • Referans28. Ashrafi B, Rashidipour M, Marzban A, Soroush S, Azadpour M, Delfaniet S, al. Mentha piperita essential oils loaded in a chitosan nanogel with inhibitory effect on biofilm formation against S. mutans on the dental surface. Carbohydr Polym 2019;212:142-9.
  • Referans29. Raghavan R, Devi MS, Varghese M, Joseph A, Madhavan SS, Sreedevi PV. Effectiveness of Mentha piperita leaf extracts against oral pathogens: An in vitro study. J Contemp Dent 2018;19:1042-6.
  • Referans30. Sookto T, Srithavaj T, Thaweboon S, Thaweboon B, Shrestha B. In vitro effects of Salvia officinalis L. essential oil on Candida albicans. Asian Pac J Trop Biomed 2013;3:376-80.
  • Referans31. Narayanan N, Thangavelu L. Salvia officinalis in dentistry. Dent Hypotheses 2015;6:27-30.
  • Referans32. Shahriari S, Barekatain M, Shahtalebi MA, Farhad SZ. Evaluation of preventive antibacterial properties of a glass-ionomer cement containing purified powder of Salvia officinalis: An In vitro Study. Int J Prev Med 2019;10:110.
  • Referans33. Fawzi M, Kamel Z, Farhan S. Anti-inflammatory effect of sage (Salvia officinalis) extracts on oral health. Iraqi Dent J 2017;39:1-6.
  • Referans34. Al-Lamy HAH, Al-Mizraqchi AS. Antibacterial efficiency of salvia officinalis extracts and their effect on growth, adherence and acid production of oral Mutans Streptococci. J Baghdad Coll Dent 2012;24:153-7.
  • Referans35. Aly M, Hanafy R. Assessment of antibacterial effect of Salvia officinalis modified glass ionomer cement: An in vitro study. Egyptian Dent J 2020;66:809-13.
  • Referans36. Beheshti-Rouy M, Azarsina M, Rezaie-Soufi L, Alikhani MY, Roshanaie G, Komaki S. The antibacterial effect of sage extract (Salvia officinalis) mouthwash against Streptococcus mutans in dental plaque: a randomized clinical trial. Iran J Microbiol 2015;7:173-7.
  • Referans37. Smullen J, Finney M, Storey DM, Foster HA. Prevention of artificial dental plaque formation in vitro by plant extracts. J Appl Microbiol 2012;113:964-73.
  • Referans38. Sharma S, Hegde V. Comparative evaluation of antifungal activity of melaleuca oil and fluconazole when incorporated in tissue conditioner: an in vitro study. J Prosthodont 2014;23:367-73.
  • Referans39. Sroisiri T, Boonyanit T. Inhibition of candida adhesion to denture acrylic by Boesenbergia pandurata. Asian Pac J Trop Med 2010;3:272-5.
  • Referans40. Amornvit P, Choonharuangdej S, Srithavaj T. Lemongrass-incorporated tissue conditioner against Candida albicans culture. J Clin Diagnostic Res 2014;8:ZC50-2.
  • Referans41. Barua DR, Basavanna JM, Varghese RK. Efficacy of neem extract and three antimicrobial agents incorporated into tissue conditioner in inhibiting the growth of C. albicans and S. mutans. J Clin Diagnostic Res 2017;11:ZC97-101.
  • Referans42. Mertas A, Garbusińska A, Szliszka E, Jureczko A, Kowalska M, Król W. The influence of tea tree oil (Melaleuca alternifolia) on fluconazole activity against fluconazole-resistant Candida albicans strains. Biomed Res Int. 2015;2015:590470.
  • Referans43. Falah-Tafti A, Jafari AA, Lotfi-Kamran MH, Fallahzadeh H, Hayan RS. A comparison of the efficacy of nystatin and fluconazole incorporated into tissue conditioner on the in vitro attachment and colonization of Candida albicans. J Dent Res 2010;7:18-22.
  • Referans44. Rawat P, Agarwal S, Tripathi S. Effect of addition of antifungal agents on physical and biological properties of a tissue conditioner: An in-vitro study. Adv Pharm Bull 2017;7:485-90.
  • Referans45. Muttagi S, Subramanya JK. Effect of incorporating seed oils on the antifungal property, surface roughness, wettability, weight change, and glucose sorption of a soft liner. J Prosthet Dent 2017;117:178-85.
  • Referans46. Pachava KR, Nadendla LK, Alluri LSC, Tahseen H, Sajja NP. In vitro antifungal evaluation of denture soft liner incorporated with tea tree oil: A new therapeutic approach towards denture stomatitis. J Clin Diagnostic Res 2015;9:ZC62-64.
  • Referans47. Abdulwahhab AR, Jassim RK. The effect of aloe vera extract on adherence of candida albicans and other properties of heat cure denture soft lining material. Int J Med Health Res 2018;7:94-103.
  • Referans48. Kumar G, Jalaluddin M, Rout P, Mohanty R, Dileep C. Emerging trends of herbal care in dentistry. J Clin Diagnostic Res 2013;7:1827-9.
  • Referans49. Azaizeh H, Fulder S, Khalil K, Said O. Ethnobotanical knowledge of local Arab practitioners in the Middle Eastern region. Fitoterapia 2003;74:98-108.

CAN ANTIBACTERIAL AND ANTIFUNGAL EFFECTIVENESS BE PROVIDED BY ADDING MEDICINAL PLANTS TO TISSUE CONDITIONERS?

Yıl 2023, , 165 - 174, 18.01.2023
https://doi.org/10.54617/adoklinikbilimler.1128243

Öz

The aim of this study is to review the literature on the addition of medicinal plants to tissue conditioners in order to benefit from their anti-inflammatory, antibacterial and antioxidant properties and to provide evidence-based information for a successful treatment. In this study, a literature search was conducted in Medline database via PubMed in order to evaluate the antimicrobial and antifungal properties of plants in dentistry and to examine the results obtained when added to tissue conditioners. As a result of the evaluated articles, it has been determined that the addition of plants to tissue conditioners can be an alternative supportive treatment option in dentistry. However, after all the evaluations, further studies are needed in terms of the long-term success and clinical use of these applications.

Proje Numarası

Yok

Kaynakça

  • Referans1. Pattanaik S, Vikas B, Pattanaik B, Sahu S, Lodam S. Denture stomatitis: a literature review. J Indian Acad Oral Med Radiol 2010;22:136-40.
  • Referans2. Zissis A, Yannikakis S, Harrison A. Comparison of denture stomatitis prevalence in 2 population groups. Int J Prosthodont 2006;19:621-5.
  • Referans3. Silva MM, Mima EG, Colombo AL, Sanitá PV, Jorge JH, Massucato EM, et al. Comparison of denture microwave disinfection and conventional antifungal therapy in the treatment of denture stomatitis: a randomized clinical study. Oral Surg Oral Med Oral Pathol Oral Radiol 2012;114:469-79.
  • Referans4. Mima EG, Vergani CE, Machado AL, Massucato EM, Colombo AL, Bagnato VS, et al. Comparison of Photodynamic Therapy versus conventional antifungal therapy for the treatment of denture stomatitis: a randomized clinical trial. Clin Microbiol Infect 2012;18:E380-8.
  • Referans5. Darwazeh AM-G, Al-Refai S, Al-Mojaiwel S. Isolation of Candida species from the oral cavity and fingertips of complete denture wearers. J Prosthet Dent 2001;86:420-3.
  • Referans6. Barbeau J, Séguin J, Goulet JP, de Koninck L, Avon SL, Lalonde B, et al. Reassessing the presence of Candida albicans in denture-related stomatitis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003;95:51-9.
  • Referans7. Yamamoto D, Shinohara Y, Nagadome H, Terada Y. Development of tissue conditioner capable of binding with anti-microbial protein lactoferrin. J Prosthodont Res 2009;53:136-41.
  • Referans8. Amin WM, Al-Ali MH, Salim NA, Al-Tarawneh SK. A new form of intraoral delivery of antifungal drugs for the treatment of denture-induced oral candidosis. Eur J Dent 2009;3:257-66.
  • Referans9. Buggapati L. Herbs in dentistry. Int J Pharm Sci Invent 2016;5:7-12.
  • Referans10. Rotblatt M, Ziment I, eds. Evidence-Based Herbal Medicine. Philadelphia: Hanley & Belfus Inc, 2002.
  • Referans11. Taheri JB, Azimi S, Rafieian N, Zanjani HA. Herbs in dentistry. International Dental Journal. 2011;61:287-96.
  • Referans12. Bonou J, Baba-Moussa F, Adéoti Z, Ahouandjinou H, Dougnon V, Dossa D, et al. Antimicrobial activity of essential oils of Lippia multiflora, Eugenia caryophyllata, Mentha piperita and Zingiber officinale on five oral-dental microorganisms. J Pharmacogn Phytochem 2016;5:271-6.
  • Referans13. Krishnamoorthy G, Narayana AI, Peralam PY, Balkrishanan D. To study the effect of Cocos nucifera oil when incorporated into tissue conditioner on its tensile strength and antifungal activity: An in vitro study. J Indian Prosthodont Soc 2019;19:225-32.
  • Referans14. Choonharuangdej S, Amornvit P, Srithavaj T, Alam MK. In vitro anti-candida effect of Thai herbs supplemented in tissue conditioner. Int Med J 2014;21:331-4.
  • Referans15. Srivatstava A, Ginjupalli K, Perampalli NU, Bhat N, Ballal M. Evaluation of the properties of a tissue conditioner containing origanum oil as an antifungal additive. J Prosthet Dent 2013;110:313-9.
  • Referans16. Carretto CFP, Navas EAFA, Paradella TC, Oliveira LD, Junqueira JC, Jorge AOC. Efeitos do chá de tomilho sobre a aderência in vitro de Streptococcus mutans ao esmalte dentário e Candida albicans à resina acrílica. Rev odontol UNESP 2013;36:281-6.
  • Referans17. Gonçalves G, Bottaro M, Nilson A. Effect of the Thymus vulgaris essential oil on the growth of Streptococcus mutans. J Appl Pharm Sci 2011;32:375-80.
  • Referans18. Hosseinzadeh S, Jafarikukhdan A, Hosseini A, Armand R. The application of medicinal plants in traditional and modern medicine: a review of Thymus vulgaris. Int J Clin Med 2015;6:635-42.
  • Referans19. Newman DJ, Cragg GM. Natural products as sources of new drugs over the last 25 years. J Nat Prod 2007;70:461-77.
  • Referans20. Al-Timimi EA, Mohammed AC. Effect of thymus vulgaris extract on streptococci and mutans streptococci, in comparison to chlorhexidine gluconate (in vivo study). J Baghdad Coll Dent 2012;24:116-21.
  • Referans21. Fani M, Kohanteb J. In vitro antimicrobial activity of Thymus vulgaris essential oil against major oral pathogens. Evid Based Complementary Altern Med 2017;22(4):660-666.
  • Referans22. Kavianirad F, Bahador N, Naseri N, Baherimoghadam T, Safaeian R. The antifungal effect of thymus vulgaris on isolated candida albicans from the surface of removable orthodontic appliances. Herb Med J 2019;4(2):55-64.
  • Referans23. Rasooli I, Shayegh S, Taghizadeh M, Astaneh SA. Rosemarinus officinalis and Thymus eriocalyx essential oils combat in vitro and in vivo dental biofilm formation. Pharmacogn Mag 2008;4:65-72.
  • Referans24. Hassan A, Hassan A. In vitro antimicrobial activity of thymus vulgaris, origanum vulgare and rosmarinus officinalis against dental caries pathogens. Ibn al-Haitham J Pure Appl Sci 2017;25:33-9.
  • Referans25. Singh R, Shushni MA, Belkheir A. Antibacterial and antioxidant activities of Mentha piperita L. Arab J Chem 2015;8:322-8.
  • Referans26. Shayegh S, Rasooli I, Taghizadeh M, Alipoor Astaneh SD. Phytotherapeutic inhibition of supragingival dental plaque. Nat Prod Res 2008;22:428-39.
  • Referans27. Rasooli I, Shayegh S, Taghizadeh M, Astaneh SDA. Phytotherapeutic prevention of dental biofilm formation. Phytother Res 2008;22:1162-7.
  • Referans28. Ashrafi B, Rashidipour M, Marzban A, Soroush S, Azadpour M, Delfaniet S, al. Mentha piperita essential oils loaded in a chitosan nanogel with inhibitory effect on biofilm formation against S. mutans on the dental surface. Carbohydr Polym 2019;212:142-9.
  • Referans29. Raghavan R, Devi MS, Varghese M, Joseph A, Madhavan SS, Sreedevi PV. Effectiveness of Mentha piperita leaf extracts against oral pathogens: An in vitro study. J Contemp Dent 2018;19:1042-6.
  • Referans30. Sookto T, Srithavaj T, Thaweboon S, Thaweboon B, Shrestha B. In vitro effects of Salvia officinalis L. essential oil on Candida albicans. Asian Pac J Trop Biomed 2013;3:376-80.
  • Referans31. Narayanan N, Thangavelu L. Salvia officinalis in dentistry. Dent Hypotheses 2015;6:27-30.
  • Referans32. Shahriari S, Barekatain M, Shahtalebi MA, Farhad SZ. Evaluation of preventive antibacterial properties of a glass-ionomer cement containing purified powder of Salvia officinalis: An In vitro Study. Int J Prev Med 2019;10:110.
  • Referans33. Fawzi M, Kamel Z, Farhan S. Anti-inflammatory effect of sage (Salvia officinalis) extracts on oral health. Iraqi Dent J 2017;39:1-6.
  • Referans34. Al-Lamy HAH, Al-Mizraqchi AS. Antibacterial efficiency of salvia officinalis extracts and their effect on growth, adherence and acid production of oral Mutans Streptococci. J Baghdad Coll Dent 2012;24:153-7.
  • Referans35. Aly M, Hanafy R. Assessment of antibacterial effect of Salvia officinalis modified glass ionomer cement: An in vitro study. Egyptian Dent J 2020;66:809-13.
  • Referans36. Beheshti-Rouy M, Azarsina M, Rezaie-Soufi L, Alikhani MY, Roshanaie G, Komaki S. The antibacterial effect of sage extract (Salvia officinalis) mouthwash against Streptococcus mutans in dental plaque: a randomized clinical trial. Iran J Microbiol 2015;7:173-7.
  • Referans37. Smullen J, Finney M, Storey DM, Foster HA. Prevention of artificial dental plaque formation in vitro by plant extracts. J Appl Microbiol 2012;113:964-73.
  • Referans38. Sharma S, Hegde V. Comparative evaluation of antifungal activity of melaleuca oil and fluconazole when incorporated in tissue conditioner: an in vitro study. J Prosthodont 2014;23:367-73.
  • Referans39. Sroisiri T, Boonyanit T. Inhibition of candida adhesion to denture acrylic by Boesenbergia pandurata. Asian Pac J Trop Med 2010;3:272-5.
  • Referans40. Amornvit P, Choonharuangdej S, Srithavaj T. Lemongrass-incorporated tissue conditioner against Candida albicans culture. J Clin Diagnostic Res 2014;8:ZC50-2.
  • Referans41. Barua DR, Basavanna JM, Varghese RK. Efficacy of neem extract and three antimicrobial agents incorporated into tissue conditioner in inhibiting the growth of C. albicans and S. mutans. J Clin Diagnostic Res 2017;11:ZC97-101.
  • Referans42. Mertas A, Garbusińska A, Szliszka E, Jureczko A, Kowalska M, Król W. The influence of tea tree oil (Melaleuca alternifolia) on fluconazole activity against fluconazole-resistant Candida albicans strains. Biomed Res Int. 2015;2015:590470.
  • Referans43. Falah-Tafti A, Jafari AA, Lotfi-Kamran MH, Fallahzadeh H, Hayan RS. A comparison of the efficacy of nystatin and fluconazole incorporated into tissue conditioner on the in vitro attachment and colonization of Candida albicans. J Dent Res 2010;7:18-22.
  • Referans44. Rawat P, Agarwal S, Tripathi S. Effect of addition of antifungal agents on physical and biological properties of a tissue conditioner: An in-vitro study. Adv Pharm Bull 2017;7:485-90.
  • Referans45. Muttagi S, Subramanya JK. Effect of incorporating seed oils on the antifungal property, surface roughness, wettability, weight change, and glucose sorption of a soft liner. J Prosthet Dent 2017;117:178-85.
  • Referans46. Pachava KR, Nadendla LK, Alluri LSC, Tahseen H, Sajja NP. In vitro antifungal evaluation of denture soft liner incorporated with tea tree oil: A new therapeutic approach towards denture stomatitis. J Clin Diagnostic Res 2015;9:ZC62-64.
  • Referans47. Abdulwahhab AR, Jassim RK. The effect of aloe vera extract on adherence of candida albicans and other properties of heat cure denture soft lining material. Int J Med Health Res 2018;7:94-103.
  • Referans48. Kumar G, Jalaluddin M, Rout P, Mohanty R, Dileep C. Emerging trends of herbal care in dentistry. J Clin Diagnostic Res 2013;7:1827-9.
  • Referans49. Azaizeh H, Fulder S, Khalil K, Said O. Ethnobotanical knowledge of local Arab practitioners in the Middle Eastern region. Fitoterapia 2003;74:98-108.
Toplam 49 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Diş Hekimliği
Bölüm Derleme
Yazarlar

Nevin Tas 0000-0001-8261-7060

Ferhan Egilmez 0000-0001-9325-8761

Proje Numarası Yok
Yayımlanma Tarihi 18 Ocak 2023
Gönderilme Tarihi 9 Haziran 2022
Yayımlandığı Sayı Yıl 2023

Kaynak Göster

Vancouver Tas N, Egilmez F. Tıbbi Bitkilerin Doku Şartlandırıcılara İlave Edilmesiyle Antibakteriyel ve Antifungal Etkinlik Sağlanabilir Mi?. ADO Klinik Bilimler Dergisi. 2023;12(1):165-74.