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İNSAN SAĞLIĞI VE BESLENME FİZYOLOJİSİ AÇISINDAN MAGNEZYUM

Yıl 2019, Cilt: 2 Sayı: 3, 26 - 33, 01.01.2019

Fatma Ergün

Öz

Canlıların yaşamsal faaliyetlerinde önemli işlevlere sahip olan magnezyum, insan vücudunda, intrasellüler miktar olarak potasyumdan sonra ikinci, genel olarak vücutta 70 kg’lık bir insanda 2000 mEq bulunan dördüncü iz elementtir. Bu derlemede; çok sayıda enzimin reaksiyonunda aktif olarak görev alan magnezyumun genel ve fizyolojik özellikleri, sağlık açısından önemi, eksikliğine ve fazlalığına bağlı metabolizma bozuklukları ve vücut magnezyum dengesinde ikinci derece etkili olan gastrointestinal emilimini etkileyen faktörler özetlenmeye çalışılmıştır

Anahtar Kelimeler

Magnezyum Beslenme Sindirim Hipomagnezemi Hipermagnezemi

Kaynakça

  • Altura BM, Altura BT, Carella A, et al. Mg+2- Ca+2 interaction in contractility of vascular smooth muscle: Mg+2 versus organic calcium channel blockers on myogenic tone and agonist-induced responsivenss of blood vessels, Can. J. Physiol. Pharmacol.1986; 65: 729-745.
  • Altura BT, Brust M, Bloom S, et al. Magnesium dietary intake modulates blood lipid levels and atherogenesis. Proc. Natl. Acad. Sci 1990; 87: 1840-44.
  • Altura BM, Altura BT. Cardiovascular risk factors and magnesium: relationships to atherosclerosis, ischemic heart disease and hypertension, Magnes Trace Elem,1991-92:182-92.
  • Altura BM, Zhang A, Altura BT. Magnesium,hypertensive vascular diseases, atherogenesis, subcellüler compartmentation of Ca+2 and Mg+2 and vascular contractility, Miner Electrolyte Metab,1993; 19: 323-336.
  • Alvarez-Lefmans FJ, Giraldez F, Gamino SM. Intracellular free magnesium in excitable cells: Its measurement and its biologic significance. Can J Physiol Pharmacol 1987; 65: 915-25.
  • Anne K. Magnesium and calcium in drinking water and heart diseases. Encyclopedia of Environmental Health. ; 535-544. Barbagallo M, Dominguez LJ, Galioto A, et al. Role of magnesium in insulin action, diabetes and cardio- metabolic syndrome X. Mol Aspects Med 2003; 24: 39-52.
  • Bohl CH, Volpe SL. Magnesium and exercise. Critical Rev Food Sci Nutr 2002; 42: 533-63.
  • Bringhurst FR, Demay MB, Kronenberg M. Hormones and disorders of mineral metabolism. In Williams Textbook of Endocrinology. Eds: Kronenberg HM, Melmed S, Polonsky KS, Larsen PR. Chapter 27, 11th ed. Saunders, Philadelphia 2008; 1203-1268.
  • Bringhurst FR, Demay MB, Krane SM, Kronenberg HM. Bone and mineral metabolism in health and disease. In Harrison’s Endocrinology. Eds: Jameson JL. Chapter 25, 2nd ed. McGraw Hill. New York, 2010; 388-405.
  • Cari AB, Ashwood E. Tietz textbook of Clinical Chemistry;3 ed.1999; 1034-1036, 1408-1410, 1441-1442.
  • Costello R, Wallace TC, Rosanoff A. Magnesium. Adv Nutr 2016; 7: 199-201.
  • Dahl C, Sogaard AJ, Tell GS, et al. Nationwide data on municipal drinking water and hip fracture: Could calcium and magnesium be protective? A NOREPOS study. Bone 2013; 57: 84-91.
  • Elin RJ. Magnesium metabolism in health and disease. Dis Mon 1988; 34: 161-219.
  • Glasdam SM, Glasdam S, Peters GH. The importance of magnesium in the human body: a systematic literature review. Advances in Clinical Chemistry 2016; 73: 169-187.
  • Gröber U, Schmidt J, Kisters K. Magnesium in prevention and therapy. Nutrients 2015; 7: 8199-8226.
  • Keskin H, 1975, Gıda Kimyası. İstanbul Ünv. Yayınları Sayı: 1980, Şirketi Mürettibiye Basımevi, İstanbul.
  • Lang UE, Beglinger C, Schweinfurth N, et al. Nutritional Aspects of Depression. Cell Physiol Biochem 2015; : 1029-43.
  • Lee EJ, Ayoub IA, Harris FB, et al. Mexiletine and magnesium independently, but not combined, protect against permenant focal cerebral ischemia in Wistar rats. J Neurosci Res 1999; 58: 442-48.
  • Maclntyre I, Boss S, Troughton VA, Parathyroid hormoneand magnesium homocstasis. Nature 1963; 198: 1058- ,
  • McLean RM. Magnesium and its therapeutic uses: A review. Am J Med 1994; 96:63-76.
  • Manuel Y, Keenoy B, Moorkens G, et al. Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: Effects of supplementation with magnesium. J Am Coll Nutr 2000; 19: 374-82.
  • Maier JAM, Mazur A. Magnesium. Reference Module in Food Science Encyclopedia of Food and Health. 2016; 592.
  • Mascarenhas R, Vashistha H, Kumbala D. Magnesium Disorders. Hosp Med Clin 2015; 549-564.
  • Marino PL. Calcium and magnesium in critical illness: A practical approach. In: Sivak ED, Higgins TL, Seiver A, eds. The high risk patient: Management of the critically ill. Baltimore: Williams and Wilkins, 1995; 1183-95.
  • Özgürtaş T ve Kutluay T. Magnezyumun metabolizması ve ölçümü. T Klin Tıp Bilimleri 2002; 22: 530-534
  • Quamme GA, Dirks JH. The physiology of renal magnesium handling. Renal Physiol. 1986; 9: 257-269.
  • Pham PCT, Pham PAT, Pham SV, Pham PTT, Pham PMT, Pham PTT. Hypomagnesemia: a clinical perspective. International Journal of Nephrology and Renovascular Disease 2014; 7: 219-230.
  • Peuhkuri K, Sihlova N. Diet promotes sleep duration and quality, Nutrition Research 2012; 32: 309-319.
  • Rayssiguer Y. Role of magnesium and potassium in pathogenesis of arteriosclerosis. Magnesium 1984; 3(4-6): 38.
  • Reinhart RA. Magnesium deficiency: Recognition and treatment in emergency medicine setting. Am J Emerg Med 1992; 10: 78-83.
  • Sawka MN, Montain SJ. Fluid and electrolyte supplementation for exercise heat stress. Am J Clin Nutr 2000; 72: 72.
  • Seo JW, Park TJ. Magnesium metabolism. Electrolyte & Blood Pressure 2008; 6: 86-95.
  • Sözen T. Metabolik Kemik Hastalıkları. 2013 Ankara.17-57.
  • Şahin ÖA. Akut İskemik İnmede Magnezyum Düzeyinin Risk ve Prognostik Faktör Olarak Değerlendirilmesi Uzmanlık Tezi Dr. İstanbul-2008. Türkiye www.gidahareketi.org/su/ambalajli_sular_tablosu.pdf Erişim Tarihi: 01.01.2018. Su Raporu Tablosu 05.2014 Güncelleme No:9
  • Wallach J. Interpretation of Diagnostic Tests: A synopsis of laboratory medicine fifth edition, Little, Brown and Company 2000; pg 49.
  • Wen SF, Wong NL, Dirks JH. Evidence for renal magnesium secretion during magnesium infusion in the dog. Am J Physiol. 1971; 220: 33-37.
  • Whang R. Magnesium deficiency: Pathogenesis, prevelance, and clinical implications. Am J Med 1987; 82: 24
  • Whang R, Ryder KW. Frequency of hipomagnesemi and hypermagnesemi: Requested vs routine. JAMA 1990; : 3063-4.
  • White RE, Hartzell HO. Magnesium ions in cardiac function. Biochem Pharmacol 1989; 38: 859-67.
  • Worcester EM, Coe FL. Nephrolithiasis. Prim Care Clin Office Pract 2008; 35: 369-391,

Yıl 2019, Cilt: 2 Sayı: 3, 26 - 33, 01.01.2019

Fatma Ergün

Öz

Magnesium having important functions in the vital activities of living things; In the human body, it is the fourth trace element found in the second after potassium, in general in the body, generally in the body 2000 mEq in a 70 kg human . In this review; The general and physiological characteristics of Magnesium, which is active in the reaction of thousands of enzymes, the importance of health, metabolic disorders due to deficiency and excess, and factors affecting the gastrointestinal absorption of body magnesium balance are tried to be summarized briefly

Anahtar Kelimeler

Magnesium Nutrition Digestion Hypomagnesemia Hypermagnezemia

Kaynakça

  • Altura BM, Altura BT, Carella A, et al. Mg+2- Ca+2 interaction in contractility of vascular smooth muscle: Mg+2 versus organic calcium channel blockers on myogenic tone and agonist-induced responsivenss of blood vessels, Can. J. Physiol. Pharmacol.1986; 65: 729-745.
  • Altura BT, Brust M, Bloom S, et al. Magnesium dietary intake modulates blood lipid levels and atherogenesis. Proc. Natl. Acad. Sci 1990; 87: 1840-44.
  • Altura BM, Altura BT. Cardiovascular risk factors and magnesium: relationships to atherosclerosis, ischemic heart disease and hypertension, Magnes Trace Elem,1991-92:182-92.
  • Altura BM, Zhang A, Altura BT. Magnesium,hypertensive vascular diseases, atherogenesis, subcellüler compartmentation of Ca+2 and Mg+2 and vascular contractility, Miner Electrolyte Metab,1993; 19: 323-336.
  • Alvarez-Lefmans FJ, Giraldez F, Gamino SM. Intracellular free magnesium in excitable cells: Its measurement and its biologic significance. Can J Physiol Pharmacol 1987; 65: 915-25.
  • Anne K. Magnesium and calcium in drinking water and heart diseases. Encyclopedia of Environmental Health. ; 535-544. Barbagallo M, Dominguez LJ, Galioto A, et al. Role of magnesium in insulin action, diabetes and cardio- metabolic syndrome X. Mol Aspects Med 2003; 24: 39-52.
  • Bohl CH, Volpe SL. Magnesium and exercise. Critical Rev Food Sci Nutr 2002; 42: 533-63.
  • Bringhurst FR, Demay MB, Kronenberg M. Hormones and disorders of mineral metabolism. In Williams Textbook of Endocrinology. Eds: Kronenberg HM, Melmed S, Polonsky KS, Larsen PR. Chapter 27, 11th ed. Saunders, Philadelphia 2008; 1203-1268.
  • Bringhurst FR, Demay MB, Krane SM, Kronenberg HM. Bone and mineral metabolism in health and disease. In Harrison’s Endocrinology. Eds: Jameson JL. Chapter 25, 2nd ed. McGraw Hill. New York, 2010; 388-405.
  • Cari AB, Ashwood E. Tietz textbook of Clinical Chemistry;3 ed.1999; 1034-1036, 1408-1410, 1441-1442.
  • Costello R, Wallace TC, Rosanoff A. Magnesium. Adv Nutr 2016; 7: 199-201.
  • Dahl C, Sogaard AJ, Tell GS, et al. Nationwide data on municipal drinking water and hip fracture: Could calcium and magnesium be protective? A NOREPOS study. Bone 2013; 57: 84-91.
  • Elin RJ. Magnesium metabolism in health and disease. Dis Mon 1988; 34: 161-219.
  • Glasdam SM, Glasdam S, Peters GH. The importance of magnesium in the human body: a systematic literature review. Advances in Clinical Chemistry 2016; 73: 169-187.
  • Gröber U, Schmidt J, Kisters K. Magnesium in prevention and therapy. Nutrients 2015; 7: 8199-8226.
  • Keskin H, 1975, Gıda Kimyası. İstanbul Ünv. Yayınları Sayı: 1980, Şirketi Mürettibiye Basımevi, İstanbul.
  • Lang UE, Beglinger C, Schweinfurth N, et al. Nutritional Aspects of Depression. Cell Physiol Biochem 2015; : 1029-43.
  • Lee EJ, Ayoub IA, Harris FB, et al. Mexiletine and magnesium independently, but not combined, protect against permenant focal cerebral ischemia in Wistar rats. J Neurosci Res 1999; 58: 442-48.
  • Maclntyre I, Boss S, Troughton VA, Parathyroid hormoneand magnesium homocstasis. Nature 1963; 198: 1058- ,
  • McLean RM. Magnesium and its therapeutic uses: A review. Am J Med 1994; 96:63-76.
  • Manuel Y, Keenoy B, Moorkens G, et al. Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: Effects of supplementation with magnesium. J Am Coll Nutr 2000; 19: 374-82.
  • Maier JAM, Mazur A. Magnesium. Reference Module in Food Science Encyclopedia of Food and Health. 2016; 592.
  • Mascarenhas R, Vashistha H, Kumbala D. Magnesium Disorders. Hosp Med Clin 2015; 549-564.
  • Marino PL. Calcium and magnesium in critical illness: A practical approach. In: Sivak ED, Higgins TL, Seiver A, eds. The high risk patient: Management of the critically ill. Baltimore: Williams and Wilkins, 1995; 1183-95.
  • Özgürtaş T ve Kutluay T. Magnezyumun metabolizması ve ölçümü. T Klin Tıp Bilimleri 2002; 22: 530-534
  • Quamme GA, Dirks JH. The physiology of renal magnesium handling. Renal Physiol. 1986; 9: 257-269.
  • Pham PCT, Pham PAT, Pham SV, Pham PTT, Pham PMT, Pham PTT. Hypomagnesemia: a clinical perspective. International Journal of Nephrology and Renovascular Disease 2014; 7: 219-230.
  • Peuhkuri K, Sihlova N. Diet promotes sleep duration and quality, Nutrition Research 2012; 32: 309-319.
  • Rayssiguer Y. Role of magnesium and potassium in pathogenesis of arteriosclerosis. Magnesium 1984; 3(4-6): 38.
  • Reinhart RA. Magnesium deficiency: Recognition and treatment in emergency medicine setting. Am J Emerg Med 1992; 10: 78-83.
  • Sawka MN, Montain SJ. Fluid and electrolyte supplementation for exercise heat stress. Am J Clin Nutr 2000; 72: 72.
  • Seo JW, Park TJ. Magnesium metabolism. Electrolyte & Blood Pressure 2008; 6: 86-95.
  • Sözen T. Metabolik Kemik Hastalıkları. 2013 Ankara.17-57.
  • Şahin ÖA. Akut İskemik İnmede Magnezyum Düzeyinin Risk ve Prognostik Faktör Olarak Değerlendirilmesi Uzmanlık Tezi Dr. İstanbul-2008. Türkiye www.gidahareketi.org/su/ambalajli_sular_tablosu.pdf Erişim Tarihi: 01.01.2018. Su Raporu Tablosu 05.2014 Güncelleme No:9
  • Wallach J. Interpretation of Diagnostic Tests: A synopsis of laboratory medicine fifth edition, Little, Brown and Company 2000; pg 49.
  • Wen SF, Wong NL, Dirks JH. Evidence for renal magnesium secretion during magnesium infusion in the dog. Am J Physiol. 1971; 220: 33-37.
  • Whang R. Magnesium deficiency: Pathogenesis, prevelance, and clinical implications. Am J Med 1987; 82: 24
  • Whang R, Ryder KW. Frequency of hipomagnesemi and hypermagnesemi: Requested vs routine. JAMA 1990; : 3063-4.
  • White RE, Hartzell HO. Magnesium ions in cardiac function. Biochem Pharmacol 1989; 38: 859-67.
  • Worcester EM, Coe FL. Nephrolithiasis. Prim Care Clin Office Pract 2008; 35: 369-391,
Toplam 40 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Araştırma Makalesi
Yazarlar

Fatma Ergün Bu kişi benim

Yayımlanma Tarihi 1 Ocak 2019
Yayımlandığı Sayı Yıl 2019 Cilt: 2 Sayı: 3

Kaynak Göster

APA Ergün, F. (2019). İNSAN SAĞLIĞI VE BESLENME FİZYOLOJİSİ AÇISINDAN MAGNEZYUM. Kırşehir Ahi Evran Üniversitesi Sağlık Bilimleri Dergisi, 2(3), 26-33.

Dergimiz; Türk Medline, Sobiad Atıf Dizini, Türk Eğitim İndeksi, Türkiye Atıf Dizini (Turkiye Citation Index)' te taranmaktadır.


Dergimizin Önceki Editörleri:

2017-2019: Doç. Dr. Rıdvan Karabulut


Dr. Öğr. Üyesi Elif Tuba KOÇ, aniden aramızdan ayrıldığı güne kadar, dergimize Çocuk Sağlığı ve Hastalıkları Hemşireliği alanında alan editörü olarak önemli katkılar sağladı. Onun çaba ve gayretini, değerli emeğini ve aziz hatırasını saygı, sevgi ve özlemle anıyoruz.