Rektum Adenokarsinomasının Penil Metastazi

Öz

ÖZ Metastatik penis lezyonları nadir görülen lezyonlardır. Literatürde 500'den az olgu bildirilmiştir. Bu nadir olguların yaklaşık %70' inde primer odak genitoüriner sistemdir. Akciğer, kemik ve rektumdan kaynaklanan olgular daha az sıklıkla bildirilmiştir. Bunlardan sadece 56'sında primer odak rektumdur. Metastatik penis lezyonlarının tipik semptomları yoktur. Hastalar genellikle sert, immobil, ağrısız kitle veya nodül ile başvururlar. Günümüzde en etkili görüntüleme yöntemi Manyetik Rezonans görüntülemedir. Literatürde kemoterapi, total penektomi ve radyoterapi gibi çeşitli palyatif veya küratif tedavi yöntemleri uygulanmıştır. Ancak hasta prognozu kötüdür. Bu hastalarda bildirilen medyan sağkalım yaklaşık dokuz aydır. Bu makalede, bilinen rektum adenokarsinomu olan bir hastada ortaya çıkan penis metastazını görüntüleme bulgularıyla birlikte sunmayı amaçladık.

Anahtar Kelimeler

• Penil metastaz
• Rektum adenokarsinomu
• MRG
• Gastroenteroloji
• Üroloji
• Radyoloji

Penile Metastasis of Rectum Adenocarcinoma

Abstract

Metastatic penile lesions are rare. Less than 500 cases have been reported in the literature. The primary source in approximately 70% of these rare cases is the genitourinary system. Cases originating from the lungs, bone, and rectum have been reported less frequently. In only 56 of these, the primary site was the rectum. There are no typical symptoms of metastatic penile lesions. Patients generally present with a hard, immobile, painless mass or nodule. The most effective imaging method is currently magnetic resonance imaging. Various palliative or curative treatment methods such as chemotherapy, total penectomy and radiotherapy have been reported in the literature. However, patient prognosis is still poor. The reported median survival in these patients is approximately nine months. This paper aims to present a penile metastasis occurring in a patient with known rectum adenocarcinoma, together with the imaging findings.

Keywords

• Penil metastasis
• Rectum adenocarcinoma
• MRI
• Gastroenterology
• Urology
• Radiology

Kaynakça

1. 1. Brady KL, Mercurio MG, Brown MD. Malignant tumors of the penis. Dermatol Surg 2013; 39:527-47.
2. 2. Ketata S, Boulaire JL, Soulimane B, Bargain A. Metachronous metastasis to the penis from a rectal adencarcinoma. Clin Colorectal Cancer 2007; 6:657-9.
3. 3. Polanco-Pujol L, Cano-Velasco J, Moralejo-Garate M, Bataller- Momfort V, Subira-Rios D, Fernandez CH. Penile metastasis from urothelial carcinoma: Review of literature. Arch Esp Urol 2021; 74(2):208-14.
4. 4. Wang Z, Shan J, Zhou X, Wang J, Yu G, Dong W, Huai F, Sun Q, Lu G, Ma Z, Liu H. Surgery, radiotherapy, chemotherapy, targeted therapy, and immunotherapy of rectal adenocarcinoma with penile metastasis: a case report. J Gastrointest Oncol 2023; 14(2):1155-65.
5. 5. Cherian J, Rajan S, Thwaini A, Elmasry Y, Shah T, Puri R. Secondary penile tumours revisited. Int Semin Surg Oncol. 2006; 3:33.
6. 6. Sun JJ, Zhang SY, Tian JJ, Jin BY. Penile metastasis from rectal carcinoma: A case report. World Journal of Clinical Cases 2022; 10(19): 6609-16.
7. 7. Berger AP, Rogatsch H, Hoeltl L, Steiner H, Bartsch G, Hobisch A. Late penile metastasis from primary bladder carcinoma. Urology 2003; 62:145.
8. 8. Dong Z, Qin C, Zhang Q, Zhang L, Yang H, Zhang J, Wang F. Penile metastasis of sigmoid colon carcinoma: a rare case report. BMC Urol 2015; 15:1-4.

9. 9. Yildirim M, Coskun A, Pürten M, Öztekin Ö, Ilhan E. A clinical case of the penile metastasis from the rectal carcinoma. Radiology and Oncology 2010; 44(2):121-3.
10. 10. Yin GL, Zhu JB, Fu CL, Ding RL, Zhang JM, Lin Q. Metachronous isolated penile metastasis from sigmoid colon adenocarcinoma: A case report. World Journal of Clinical Cases 2022; 10(31):11658-64.
11. 11. Lin YH, Kim JJ, Stein NB, Khera M. Malignant priapism secondary to metastatic prostate cancer: A case report and review of literature. Rev Urol 2011; 13:90–4.