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Study of the performance of the FOOT experiment

Yıl 2019, NSP2018 Özel Sayı, 86 - 92, 28.03.2019

Öz

In the last decade a continuous increase in the number
of cancer patients treated with Particle Therapy (CPT) has been registered. CPT
is still a discipline where the contribution coming from research in physics
plays an important role. For example, different studies have shown that in
proton therapy nuclear inelastic interactions of the incident beam with the
patient tissues may lead to the fragmentation of the target nuclei producing a
non negligible amount of target fragments, which may alter the estimated local
dose deposition, especially in the entrance region. On the other hand, in heavy
ion treatments, the main effect of nuclear inelastic interactions results in
the break up of the incident ion instead of the target nuclei. The produced
fragments have a longer range than the projectile, leading to an undesirable
dose deposition beyond the Bragg peak. At present there is still a lack of
complete and reliable experimental measurements of nuclear reaction cross
sections for fragments produced in the interaction with tissues nuclei (H, C,
Ca, O, N) of 60-250 MeV protons and 100-400 MeV/u carbon ions, which are the
typical energies adopted in CPT treatments. These data will be important to
develop a new generation of high quality treatment planning systems for CPT.

The FOOT (FragmentatiOn Of Target) experiment aims to
fill the gap, performing a set of measurements of nuclear fragmentation cross
sections relevant for CPT.  As far the
study of target fragmentation is concerned, the FOOT experiment will adopt an
inverse kinematic approach to overcome the difficulties related to the short
fragments range (
μm). In order to bypass the difficulties to manage a
pure hydrogen target, it has been chosen a strategy of a double target
separately made of C and C2H4 and the final cross section
on Hydrogen will be obtained by subtraction. Further interest in this type of
measurements comes from the issue of radioprotection in space missions, where
the energy to be considered is higher and close to 1 GeV/u. FOOT consists of
two different setups depending on the detection of heavy and light fragments:
the heavy fragments are detected by a high precision tracking system in
magnetic field, a time of flight measurement system and a calorimeter, while
the lighter ones by a separated emulsion chamber. The optimization and the
performance analysis of the setup have studied by means of the FLUKA(1)(2)(3)
Monte Carlo code and different detectors have been tested.





In this work, an overview of the FOOT experiment and a
report on the study of the detector performances will be presented.

Kaynakça

  • Böhlen T.T. et al, The FLUKA code: Developments and challenges for high energy and medical applications. Nuclear Data Sheets, 120, 211 (2014)
  • Battistoni G. et al, Overview of the FLUKA code. Annals of Nuclear Energy, 82, 10 (2015)
  • Battistoni G. et al, The FLUKA code: An accurate simulation tool for particle therapy. Frontiers in oncology, 6, 116 (2016)
  • Durante M. and Loeffler J., Nat. Rev. Clin. Onc., 7, no. 1, pp. 37, (2010)
  • Schardt D., Elsässer T. and Schulz-Ertner D., Rev. Mod. Phys. 82, 383, (2010)
  • Tommasino F. and Durante M., Cancers, 7, 353, (2015)
  • Dudouet J. et al, Double-differential fragmentation cross-section measurements of 95 MeV/u nucleon 12C beams on thin targets for hadron therapy, Phys. Rev. C, 88, no. 2, (2013)
  • De Lellis G. et al, Emulsion Cloud Chamber technique to measure the fragmentation of high-energy carbon beam, Jinst, 2, (2007)
  • Morrocchi et al, Development and characterization of a ∆E/TOF detector prototype for the FOOT experiment, in press on Nuclear Inst. and Methods in Physics Research, A; doi: 10.1016/j.nima.2018.09.086
  • Cho W.S. et al, OPTIMASS: A package for the minimization of kinematic mass functions with constraints, JHEP, 1601, 26 (2016)

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Yıl 2019, NSP2018 Özel Sayı, 86 - 92, 28.03.2019

Öz

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Kaynakça

  • Böhlen T.T. et al, The FLUKA code: Developments and challenges for high energy and medical applications. Nuclear Data Sheets, 120, 211 (2014)
  • Battistoni G. et al, Overview of the FLUKA code. Annals of Nuclear Energy, 82, 10 (2015)
  • Battistoni G. et al, The FLUKA code: An accurate simulation tool for particle therapy. Frontiers in oncology, 6, 116 (2016)
  • Durante M. and Loeffler J., Nat. Rev. Clin. Onc., 7, no. 1, pp. 37, (2010)
  • Schardt D., Elsässer T. and Schulz-Ertner D., Rev. Mod. Phys. 82, 383, (2010)
  • Tommasino F. and Durante M., Cancers, 7, 353, (2015)
  • Dudouet J. et al, Double-differential fragmentation cross-section measurements of 95 MeV/u nucleon 12C beams on thin targets for hadron therapy, Phys. Rev. C, 88, no. 2, (2013)
  • De Lellis G. et al, Emulsion Cloud Chamber technique to measure the fragmentation of high-energy carbon beam, Jinst, 2, (2007)
  • Morrocchi et al, Development and characterization of a ∆E/TOF detector prototype for the FOOT experiment, in press on Nuclear Inst. and Methods in Physics Research, A; doi: 10.1016/j.nima.2018.09.086
  • Cho W.S. et al, OPTIMASS: A package for the minimization of kinematic mass functions with constraints, JHEP, 1601, 26 (2016)
Toplam 10 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Makaleler
Yazarlar

Yunsheng Dong Bu kişi benim

Yayımlanma Tarihi 28 Mart 2019
Gönderilme Tarihi 4 Aralık 2018
Kabul Tarihi 16 Aralık 2018
Yayımlandığı Sayı Yıl 2019 NSP2018 Özel Sayı

Kaynak Göster

APA Dong, Y. (2019). Study of the performance of the FOOT experiment. ALKÜ Fen Bilimleri Dergisi86-92.
AMA Dong Y. Study of the performance of the FOOT experiment. ALKÜ Fen Bilimleri Dergisi. Published online 01 Mart 2019:86-92.
Chicago Dong, Yunsheng. “Study of the Performance of the FOOT Experiment”. ALKÜ Fen Bilimleri Dergisi, Mart (Mart 2019), 86-92.
EndNote Dong Y (01 Mart 2019) Study of the performance of the FOOT experiment. ALKÜ Fen Bilimleri Dergisi 86–92.
IEEE Y. Dong, “Study of the performance of the FOOT experiment”, ALKÜ Fen Bilimleri Dergisi, ss. 86–92, Mart 2019.
ISNAD Dong, Yunsheng. “Study of the Performance of the FOOT Experiment”. ALKÜ Fen Bilimleri Dergisi. Mart 2019. 86-92.
JAMA Dong Y. Study of the performance of the FOOT experiment. ALKÜ Fen Bilimleri Dergisi. 2019;:86–92.
MLA Dong, Yunsheng. “Study of the Performance of the FOOT Experiment”. ALKÜ Fen Bilimleri Dergisi, 2019, ss. 86-92.
Vancouver Dong Y. Study of the performance of the FOOT experiment. ALKÜ Fen Bilimleri Dergisi. 2019:86-92.