Relationship between deep vein thrombosis and serial chest computerized tomography severity scores in COVID-19 patients
Öz
Aim: We aimed to evaluate risk factors for deep vein thrombosis (DVT) in the lower extremities veins in COVID-19 patients and the relationship between DVT and chest Computed Tomography severity scores (CT-SS). To our knowledge, our study is the first to investigate the relationship between the occurrence of DVT and serial chest CT-SS in COVID-19 patients.
Methods: We retrospectively analyzed 131 COVID-19 patients (≥18 years) admitted to our hospital. Two radiologists examined chest CT scans and calculated CT-SS using a visual scoring system. Color Doppler ultrasounds of lower extremity veins were performed for DVT. CT Pulmonary Angiographies (CTPA) were performed on patients clinically suspected of pulmonary embolism (PE).
Results: A total of 131 patients were included in our study. 71/131 (54.2%) of the patients were male. 18/131 (13.7%) patients were treated in ICU, and 18 (13.7%) patients died. 21/131 (16%) patients had DVT in their lower extremities. Chest CTA was performed in 44/131 (33.6%) patients, and PE was detected in 10/44 patients (22.7%). PE was considerably more common in patients with DVT (p = 0.009). The occurrence of DVT was significantly associated with high first chest CT-SS (p=0.002). However, there was no association between the DVT and the second and third CT-SS. Significant associations were found between the development of DVT with elevated serum D-Dimer, CRP, and fibrinogen levels (p<0.001; p=0.014; p=0.031).
Conclusion: The risk of DVT is higher in COVID-19 patients with diffuse pulmonary involvement on chest CT at admission.
Anahtar Kelimeler
Computed tomography angiography, COVID-19, doppler ultrasonography, venous thrombosis
Destekleyen Kurum
Yok
Etik Beyan
This study was approved by the Ethical Committee of Amasya University Faculty of Medicine and was conducted according to the Declaration of Helsinki and Good Clinical Practice (approval number:62, 06 May 2021) and the requirement for informed consent was waived.
Kaynakça
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