Sağlıklı, Foliküler ve Luteal Kistli İneklerde Repeat Breeder Durumu, Fertilite Başarısı ve Bazı Kan Parametrelerinin Araştırılması

Öz

Bu çalışmada, sütçü ineklerde tedavi edilmiş foliküler ve luteal kistlerle repeat breeder oranı arasındaki ilişki araştırılmaktadır. Ayrıca bazı biyokimyasal parametreler ölçülerek gruplar arasındaki farkın belirlenmesi ve bunun fertilite başarısına etkisinin belirlenmesi amaçlanmaktadır. Çalışma foliküler kist (Grup 1; n = 30), luteal kist (Grup 2; n = 20) ve kontrol (Grup 3; n= 20) grupları olmak üzere üç grup üzerinde yürütüldü. E2 ve AST seviyeleri diğer gruplara göre Grup 3'te arttı (P<0.05; P<0.01). Kolesterol düzeyi Grup 2'de (P<0.01) en yüksekti ve Grup 3'e kıyasla Grup 1'de arttı (P<0.01). Glikoz düzeyi Grup 1'e göre Grup 2'de azaldı (P<0.05). ALP ve GGT seviyeleri diğer gruplara kıyasla Grup 2'de arttı (P<0.01). ALT düzeyi Grup 2'ye kıyasla Grup 3'te yükseldi (P<0.01). Diğer gruplarla karşılaştırıldığında, gebelik başına suni tohumlama oranı Grup 3'te azalırken (P<0.01), Grup 2'de repeat breeder oranı önemli ölçüde arttı (P<0.01). Sonuç olarak, hem luteal hem de foliküler kistlerin fertilite üzerinde yıkıcı etkileri oldu, ancak repeat breeder oranı sadece luteal kistli ineklerde artış gösterdi

Anahtar Kelimeler

• Foliküler kist
• inek
• luteal kist
• ovaryum
• repeat breeder

Investigation of Repeat Breeder Status, Fertility Success and Some Blood Parameters in Healthy, Follicular, and Luteal Cystic Cows

Abstract

The present study investigated the relationship between treated follicular and luteal cysts and repeat breeder rate in dairy cows. In addition, it was aimed to determine the difference between the groups by measuring biochemical parameters and the effect of this on fertility success. The study was comprised of three groups; follicular cyst (Group 1; n = 30), luteal cyst (Group 2; n = 20), and control (Group 3; n = 20) groups. The E2 and AST levels increased in Group 3 compared to other groups (P<0.05; P<0.01). Cholesterol level was highest in Group 2 (P<0.01), and it is also increased in Group 1 compared to Group 3 (P<0.01). Glucose level decreased in Group 2 compared to Group 1 (P<0.05). ALP and GGT levels increased in Group 2 compared to other groups (P<0.01). ALT level increased in Group 3 compared to Group 2 (P<0.01). Compared to other groups, the artificial insemination rate per pregnancy decreased in Group 3 (P<0.01), and repeat breeder status significantly increased in Group 2 (P<0.01). In conclusion, both luteal and follicular cysts have devastating effects on fertility, but repeat breeder status increased in only cows with luteal cysts.

Keywords

• Cow
• follicular cyst
• luteal cyst
• ovary
• repeat breeder

Kaynakça

1. 1. Borş SI., Borş A., 2020. Ovarian cysts, an anovulatory condition in dairy cattle. J Vet Med Sci, 82, 1515-1522.
2. 2. Pesantez JL., Ortiz O., Hernandez-Ceron J., 2016. Incidence of ovarian follicular cysts and their effect on reproductive performance in dairy cows: A case study in Mexico. Arch Med Vet, 48, 289-291.
3. 3. Yazlık MO., Çolakoğlu HE., Kaya U., 2017. İsviçre esmeri ineklerde kistik ve dominant folikül sıvılarının metabolik ve iyon kompozisyonlarının karşılaştırılması. Vet Hekim Der Derg, 88, 15-25.
4. 4. Jeengar K., Chaudhary V., Kumar A., Raiya S., Gaur M., Purohit GN., 2018. Ovarian cysts in dairy cows: old and new concepts for definition, diagnosis and therapy. Anim Reprod, 11, 63-73.
5. 5. Hombalegowda H., Ramakrishnappa N., Siddaraju NK., Sringeshwaraiah NC., Guelal S., 2019. Factors influencing cystic ovarian disease in Holstein Friesian (HF) crossbred cattle. SSR Inst Int J Life Sci, 5, 2317-2321.
6. 6. Mimoune N., Azzouz MY., Khelef D., Kaidi R., 2021. Ovarian cysts in cattle: a review. Vet Stanica, 52, 587-603.
7. 7. Mimoune N., Baazizi R., Azzouz MY., Benaissa MH., Kaidi R., 2019. Basic and new concepts of ovarian cyst pathogenesis in cattle. Vet, 68, 73-80.
8. 8. Brodzki P., Brodzki A., Krakowski L., Dabrowski R., Szczubiał M., Bochniarz M., 2019. Levels of selected cytokines and acute–phase proteins in the serum of dairy cows with cystic ovarian disease and those in follicular and luteal phases of normal ovarian cycle. Res Vet Sci, 123, 20-25.

9. 9. Nora M., Rachid K., Abdelmoumene G., Hocine BM., Yassine AM., 2018. Characterization of ovarian follicular and cystic fluids in cows. Vet, 67, 73-79
10. 10. Bartolome JA., Thatcher WW., Melendez P., Risco CA., Archbald LF., 2005. Strategies for the diagnosis and treatment of ovarian cysts in dairy cattle. J Am Vet Med Assoc, 227, 1409-1414.
11. 11. Moss N., Lean IJ., Reid SWJ., Hodgson DR., 2002. Risk factors for repeat-breeder syndrome in New South Wales dairy cows. Prev Vet Med, 54, 91-103.
12. 12. Lopez-Gatius F., Garcia-Ispierto I., 2020. Treatment with an elevated dose of the GnRH analogue dephereline in the early luteal phase improves pregnancy rates in repeat-breeder dairy cows. Theriogenology, 155, 12-16.
13. 13. Funeshima N., Miura R., Katoh T., Yaginuma H., Kitou T., Yoshimura I., Konda K., Hamano S., Shirasuna K., 2021. Metabolomic profiles of plasma and uterine luminal fluids from healthy and repeat breeder Holstein cows. BMC Vet Res, 17, 1-10.
14. 14. Nowicki A., 2021. Embryo transfer as an option to improve fertility in repeat breeder dairy cows. J Vet Sci, 65, 231-237.
15. 15. Salasel B., Mokhtari A., Taktaz T., 2010. Prevalence, risk factors for and impact of subclinical endometritis in repeat breeder dairy cows. Theriogenology, 74, 1271-1278.
16. 16. Lopez-Gatius F., Lopez-Bejar M., 2002. Reproductive performance of dairy cows with ovarian cysts after different GnRH and cloprostenol treatments. Theriogenology, 58, 1337-1348.
17. 17. Khosa BK., 2020. Repeat Breeding: A Dent to Dairy Farm Economy. Int J Curr Microbiol App Sci, 9, 4085-4091.
18. 18. Amiridis GS., Tsiligianni TH., Dovolou E., Rekkas C., Vouzaras D., Menegato I., 2009. Combined administration of gonadotropin-releasing hormone, progesterone, and meloxicam is an effective treatment for the repeat-breeder cow. Theriogenology, 72, 542-548.
19. 19. Abdalla H., de Mestre AM., Salem SE., 2020. Efficacy of ovulation synchronization with timed artificial insemination in treatment of follicular cysts in dairy cows. Theriogenology, 154, 171-180.
20. 20. Sakaguchi M., Sasamoto Y., Suzuki T., Takahashi Y., Yamada Y., 2006. Fate of cystic ovarian follicles and the subsequent fertility of early postpartum dairy cows. Vet Rec, 159, 197-201.
21. 21. Çolakoğlu HE., Yazlık MO., Pekcan M., Kaya U., Kaçar C., Vural MR., Kurt S., Yildirim MM., Bas A., Küplülü Ş., 2019. Impact of Prepartum body condition score loss on metabolic status during the transition period and subsequent fertility in Brown Swiss dairy cows. J Vet Res, 63, 375-382.
22. 22. Macmillan K., Gobikrushanth M., Helguera IL., Behrouzi A., Colazo MG., 2020. Relationships between early postpartum nutritional and metabolic profiles and subsequent reproductive performance of lactating dairy cows. Theriogenology, 151, 52-57.
23. 23. Kendall NR., Flint APF., Mann GE., 2009. Incidence and treatment of inadequate postovulatory progesterone concentrations in repeat breeder cows. Vet J, 181, 158-162.
24. 24. Ueno D., Goto A., Hazano K., Haneda S., Matsui M., 2021. Sustained high progesterone concentrations during estradiol-progesterone based estrus synchronization protocol in Japanese Black cows affects fertility by influencing preovulatory follicle size and its ovulation. Jpn J Vet Res, 69, 151-161.
25. 25. Vanholder T., Leroy JL., Dewulf J., Duchateau L., Coryn M., de Kruif A., Opsomer G., 2005. Hormonal and metabolic profiles of high-yielding dairy cows prior to ovarian cyst formation or first ovulation post partum. Reprod Domest Anim, 40, 460-467.
26. 26. Westwood CT., Lean IJ., Garvin JK., 2002. Factors influencing fertility of Holstein dairy cows: a multivariate description. J Dairy Sci, 85, 3225-3237.
27. 27. Puppel K., Kuczynska B., 2016. Metabolic profiles of cow's blood; a review. J Sci Food Agric, 96, 4321-4328.
28. 28. Jorritsma R., Wensing T., Krui, TA., Vos PL., Noordhuizen JP., 2003. Metabolic changes in early lactation and impaired reproductive performance in dairy cows. Vet Res, 34, 11-26.