Rastgele Seçilen IV Serum Setlerinin Sabit Oranlı İnfüzyona Etkileri: In-Vitro Gösterim

Yıl 2021, Cilt: 16 Sayı: 3, 330 - 335, 30.12.2021

Mümin Gökhan Şenocak Latif Emrah Yanmaz Ugur Ersoz Sıtkıcan Okur Ferda Turgut

Öz

Volumetrik infüzyon pompaları, sıvı replasmanlarının yanı sıra damar içi yolla belirli bir sürede anestezik bir maddenin sabit oranlı infüzyonunda kullanılan elektronik cihazlardır. İçerisine yerleştirilen IV (intravenöz) serum seti hortumu üzerine cihaz tarafından yapılan peristaltik bası, set içerisindeki sıvının ilerlemesini ve infüzyonunu sağlar. Pompalarda tercih edilmesi gereken IV setlerin her ne kadar peristaltik basıya uygun nitelikte tercih edilmesi gerekse de rutin klinik uygulamalarda çoğunlukla klinikten rastgele temin edilen serum setleriyle anestezi sürdürülmektedir. Bu çalışmada, bir tanesi volümetrik infüzyon pompası için özel üretilen referans IV serum seti olmak üzere toplam 15 farklı marka IV serum seti kullanıldı. Çapları ve içlerindeki ölü boşluklar ölçüldükten sonra infüzyon pompasına bağlanarak her bir serum setinden bir saat süreyle çeşme suyu geçirildi ve geçirilen sıvı dereceli silindir içerisinde biriktirilerek ölçüldü. Referans IV seti de dahil olmak üzere farklı IV setlerinin farklı hacimlerde sıvı gönderdiği gözlemlendi ve bu durum beklenen sıvı volümünü %19 oranında etkileyebileceğini gösterdi. IV setinin çapının ölü alanları ve infüzyonu yapılan sıvı hacmini etkilediği belirlendi. Sonuç olarak beklenen ve gözlenen infüzyon hacimlerinin birbiriyle örtüşebilmesi için klinikte kullanılan serum setlerinin cihazda önceden tecrübe edilmesinin bir gereklilik olduğu kanısına varıldı.

Anahtar Kelimeler

IV set, infüzyon pompası, sabit oranlı infüzyon, serum seti.

Destekleyen Kurum

Atatürk Üniversitesi Bilimsel Araştırma Projeleri Koordinasyon Birimi

Proje Numarası

TAB-2021-8927

The Effects of Randomly Selected IV Serum Sets on Constant Rate Infusion: In-Vitro Demonstration

Öz

Volumetric infusion pumps are electronic devices used for fluid replacement as well as constant rate infusion of anesthetic drugs. The device provides the infusion of the fluid in the set by performing peristaltic pressure on the IV (intravenous) serum set hose. Although IV sets are preferred by their peristaltic pressure properties, the random IV sets selected from the clinical field are mostly used in anesthesia. A reference infusion set which was a special product for a volumetric infusion pump, and fifteen different branded IV serum sets were used in this study. After measuring the diameters and dead spaces, serum sets were connected to the infusion pump, tap water was passed from each serum set for an hour, and collected in a graduated cylinder and measured. It was observed that the serum sets, including the reference set, may change the expected fluid volume by 19%. The diameter of the IV set affected the dead spaces and infused fluid volume. It was concluded that to overlap the expected and observed fluid volumes, the brands’ infusion capacity on the pump should be tested on the device before the anesthesia for the clinical fields is a requirement.

Anahtar Kelimeler

constant rate infusion, infusion pump, IV set, serum set

Proje Numarası

TAB-2021-8927

Kaynakça

• 1. Yayla S., Kacar C., Kilic E., Kaya S., Kuru M., Ermutlu C. S., Ozaydin I., Huseyinoglu U., Ogun M., 2017. The effects of intrathecal administration of bupivacaine or ropivacaine following administration of propofol in dogs undergoing ovariohysterectomy. Kafkas Univ Vet Fak Derg, 23, 363-367.
• 2. Davis H., Jensen T., Johnson A., Knowles P., Meyer R., Rucinsky R., 2013. AAHA/AAFP fluid therapy guidelines for dogs and cats. J Am Anim Hosp Assoc, 49, 149-159.
• 3. Chappell D., Jacob M., Hofmann-Kiefer K., Conzen P., Rehm M., 2008. A rational approach to perioperative fluid management. Anesthesiology, 109, 723-740.
• 4. Brandstrup B., 2006. Fluid therapy for the surgical patient. Best Pract Res Clin Anaesthesiol, 20, 265-283.
• 5. Cooper A., Lilliman M., 1985. The use of a volumetric infusion pump for the intra-arterial infusion of drugs. Ann R Coll Surg Engl, 67, 1, 11.
• 6. Neff T., Fellmann C., Fuechslin R., Gerber A., Weiss M., 2002. Evaluation of a micro-volumetric infusion pump for continuous intrathecal drug administration in cerebral spasticity. Anesthesiology, 96, A475.
• 7. Escobedo P., Ornelas D., Pozo L., Rosas R., Nemesio N., Hernandez P., 2015. Economic impact of a volumetric infusion pump (infusomat® space)+ central alarm management (one view), in the risk prevention in infusion therapy in the intensive care unit (icu) in Mexico. Health Values, 18, 7, A862.
• 8. Kemmotsu O., Hayashitani S., Kitami Z., Nagai K., Tanaka R., Kozaya T., 1982. Serum lidocaine concentrations during continuous epidural anesthesia with an infusion pump. Masui, 31, 6, 605-610.
• 9. Spadavecchia C., Schmucker N., Schatzmann U., 1999. Investigations into injection anesthesia (TIVA): of the horse with ketamine/guaifenesin/xylazin: experiences with computerized pump infusion. R Soc Chem, 80, 118-122.
• 10. Nagata O., 1998. Development of a Three-Pump Computer-Controlled-Infusion System for Total Intravenous Anesthesia with Propofol, Fentanyl, and Vecuronium: Ci nii ac jp, 377-388.
• 11. Klein S., Greengrass R., Gleason D., Nunley J., Steele S., 1999. Major ambulatory surgery with continuous regional anesthesia and a disposable infusion pump. Anesthesiology, 91, 563-565.
• 12. Sarturi V., Teixeira L., Coradini G., Milech V., Hartmann H., Linhares M., 2021. Total intravenous anesthesia with propofol associated or not with remifentanil, ketamine, or S-ketamine for laparoscopic ovariectomy in female dogs. Top Companion Anim Med, 100575.
• 13. Rastabi H., Khosravi M., Avizeh R., Moslemi M., 2021. Evaluation of the effect of lidocaine epidural injection on immunological indices in dogs under total intravenous anesthesia submitted to ovariohysterectomy. Plos one, 16, 6, e0253731.
• 14. Ashrafi B., Pretto E., Fraker C., 2019. Total intravenous anesthesia with a novel formulation of isoflurane perfluorocarbon-based nano-emulsion: Safety, efficacy and toxicity in dogs. Philadelphia, PA 19103 USA: Lippincott Williams & Wilkins, 65-66.
• 15. Liao P., Sinclair M., Valverde A., Mosley C., Chalmers H., Mackenzie S., 2017. Induction dose and recovery quality of propofol and alfaxalone with or without midazolam coinduction followed by total intravenous anesthesia in dogs. Vet Anaesth Analg, 44, 1016-1026.
• 16. Viviand X., Guidon-Attali C., Granthil C., Martin C., Francois G., 1993. Computer-assisted intravenous anesthesia: value, method and use. Ann Fr Anesth Reanim, 12, 38-47.
• 17. Ramirez Sr E., Calvache JA., 2013. Development of an interactive mobile application based simulator for total intravenous anesthesia. Anesthesiology, A1263.
• 18. Kan K., Levine WC. 2021. Infusion Pumps. Anesthesia Equipment: Elsevier, 351-67.
• 19. Thongpance N., Pititeeraphab Y., Ophasphanichayakul M., 2012. The design and construction of infusion pump calibrator. The 5th 2012 Biomedical Engineering International Conference, IEEE, 1-3.
• 20. Kim YK., Kim KH., Lee DH., Kim KS., Suh JK., Yoo HK., 1984. Measarement of Drop Factor of IV Infusion Set with Infusion Pump. Korean J Anesthesiol, 20, 782-787.
• 21. Yamashita K., Wijayathilaka TP., Kushiro T., Umar MA., Taguchi K., Muir WW., 2007. Anesthetic and cardiopulmonary effects of total intravenous anesthesia using a midazolam, ketamine and medetomidine drug combination in horses. J Vet Med Sci, 69, 7-13.
• 22. Tsai YC., Wang LY., Yeh LS., 2007. Clinical comparison of recovery from total intravenous anesthesia with propofol and inhalation anesthesia with isoflurane in dogs. J Vet Med Sci, 69, 1179-1182.
• 23. Dogan E., Yanmaz L., Senocak MG., Okumus Z., 2016. Comparison of propofol, ketamine and ketofol on intraocular pressure in New Zealand white rabbits. Rev Med Vet, 167, 18-21.
• 24. Yanmaz LE., Doğan E., Şenocak MG., Ersöz U., Sıtkıcan O., 2020. Comparison the Effect of Different Ratios of Ketamine and Propofol (Ketofol) Admixture on Anesthesia Induction in New Zealand White Rabbits. Atatürk University J Vet Sci, 15, 251-256.