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Düzeltme: PKOS Hastalarında Yüksek Kan Basıncı Sıklığı ve Bunun Klinik ve Laboratuvar Parametrelerle İlişkisi

Yıl 2022, Cilt: 11 Sayı: 1, 136 - 142, 28.02.2022
Bu makalenin ilk hali 31 Ağustos 2021 tarihinde yayımlandı. https://dergipark.org.tr/tr/pub/balikesirsbd/issue/64743/962549

Düzeltme Notu

Düzeltme Yazısı / Erratum Düzeltme: Bulmuş, Ö. & Usta, A. (2021). PKOS Hastalarında Yüksek Kan Basıncı Sıklığı ve Bunun Klinik ve Laboratuvar Parametrelerle İlişkisi . Balıkesir Sağlık Bilimleri Dergisi , 10 (2) , 173-179 . DOI: 10.53424/balikesirsbd.962549 referanslı makalede etik kurul bilgilerinin yazarlar tarafından sehven yanlış yazıldığı, bazı imla ve ifade hatalarının olduğu fark edilmiştir. Yapılan bu hatadan dolayı yazarlar okuyuculardan özür dilemektedir. Makale gerekli düzeltmeler yapılarak tekrar yayınlanmıştır.

Öz

Amaç: Polikistik over sendromlu (PKOS) hastalarda kan basıncı (KB) anormalliklerine sıklıkla rastlanmakla beraber hipertansiyon ve PKOS arasındaki ilişki tam olarak aydınlatılamamıştır. Bu çalışmadaki amacımız ACC/AHA tarafından önerilen yeni sınıflandırmaya göre PKOS’lu hastalarda KB değişikliklerini araştırmaktır. Gereç Yöntem: Çalışmada PKOS tanılı 64 hasta ile aynı yaş grubundaki PKOS olmayan 61 hastanın KB ölçümleri ve bazal karakteristik özellikleri birbiri ile karşılaştırıldı. Bulgular: Kontrol grubuyla karşılaştırıldığında, PKOS hastalarının Ferriman Gallwey skoru (p<0.0001), ortalama diyastolik kan basıncı (p= 0.0099), glukoz (p=0.0049), lökosit (p= 0.0319), nötrofil (p=0.0364) ve Lüteinizan Hormon (LH) (p=0.0018) seviyeleri istatistiksel anlamlı olarak daha yüksek bulundu. PKOS ve Kontrol grubu ACC/AHA klavuzuna göre gruplandırıldığında PKOS hastalarının %59.4’ü anormal KB sahipken kontrol grubundaki hastaların ise %47.5’inde anormal KB tespit edildi. Yapılan istatistik analizde gruplar arasında anlamlı fark tespit edildi (p=0.0343). PKOS hastalarında DKB seviyeleri ile VKİ, serum glukoz seviyesi, HOMA-IR, total kolesterol ve LDL kolesterol arasında pozitif korelasyon tespit edildi. Ayrıca PKOS hastalarında DKB ile HDL kolesterol seviyeleri arasında negatif korelasyon tespit edildi. Sonuç: Üreme dönemindeki PKOS hastalarında KB (özellikle DKB) seviyelerinin insülin direnci, hiperandrojenemi ve dislipideminin varlığıyla ilişkili olarak yükselme eğiliminde olduğu, fakat PKOS ve kontrol grubu arasında hipertansiyon görülme sıklığı açısından fark olmadığı tespit edilmiştir.

Kaynakça

  • Alexander, C.J., Tangchitnob, E.P., & Lepor, N.E. (2009). Polycystic ovary syndrome: a major unrecognized cardiovascular risk factor in women. Reviews in Obstetrics and Gynecology, 2(4), 232-239.
  • Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group. (2012). Consensus on women’s health aspects of polycystic ovary syndrome (PCOS). Human Reproduction, 27(1), 14-24. https://doi.org/ 10.1093/humrep/der396
  • Azziz, R., Woods, K.S., Reyna, R., Key, T.J., Knochenhauer, E.S., & Yildiz, B.O. (2004). The prevalence and features of the polycystic ovary syndrome in an unselected population. The Journal of Clinical Endocrinology & Metabolism, 89(6), 2745-2749. https://doi.org/10.1210/jc.2003-032046
  • Bentley-Lewis, R., Seely, E., & Dunaif, A. (2011). Ovarian hypertension: polycystic ovary syndrome. Endocrinology and Metabolism Clinics of North America, 40(2), 433-449. https://doi.org/10.1016/j.ecl.2011.01.009
  • Boomsma, C.M., Fauser, B.C., & Macklon, N.S. (2008). Pregnancy complications in women with polycystic ovary syndrome. Seminars in Reproductive Medicine, 26(1), 72-84. https://doi.org/10.1055/s-2007-992927
  • Burghen, G.A., Givens, J.R., & Kitabchi, A.E. (1980). Correlation of hyperandrogenism with hyperinsulinism in polycystic ovarian disease. The Journal of Clinical Endocrinology & Metabolism, 50(1), 113-116. https://doi.org/ 10.1210/jcem-50-1-113
  • Carmina, E. (2009). Cardiovascular risk and events in polycystic ovary syndrome. Climacteric, 12 (Suppl 1), 22-25. https://doi.org/ 10.1080/13697130903003842
  • Conway, G.S., Agrawal, R., Betteridge, D.J., & Jacobs, H.S. (1992). Risk factors for coronary artery disease in lean and obese women with the polycystic ovary syndrome. Clinical Endocrinology 37(2), 119-125. https://doi.org/ 10.1111/j.1365-2265.1992.tb02295.x Diamanti-Kandarakis, E., Alexandraki, K., Piperi, C., Aessopos, A., Paterakis T, Katsikis I., & Panidis, D. (2007). Effect of metformin administration on plasma advanced glycation end product levels in women with polycystic ovary syndrome. Metabolism, 56(1), 129-134. https://doi.org/ 10.1016/j.metabol.2006.09.006
  • Elting, M.W., Korsen, T.J., Bezemer, P.D., & Schoemaker J. (2001). Prevalence of diabetes mellitus, hypertension and cardiac complaints in a follow-up study of a Dutch PCOS population. Human Reproduction, 16(3), 556-560. https://doi.org/ 10.1093/humrep/16.3.556
  • Ferriman, D., & Gallwey, J.D. (1961). Clinical assessment of body hair growth in women. The Journal of Clinical Endocrinology & Metabolism, 21, 1440-1447. https://doi.org/ 10.1210/jcem-21-11-1440
  • Guo, X., Zhang, X., Guo, L., Li, Z., Zheng, L., Yu, S., Yang, H., Zhou, X., Zhang, X., Sun, Z., Li, J., Sun, Y. (2013). Association between pre-hypertension and cardiovascular outcomes: a systematic review and meta-analysis of prospective studies. Current Hypertension Reports, 15(6), 703-716. https://doi.org/ 10.1007/s11906-013-0403-y
  • Guo, X., Zhang, X., Zheng, L., Guo, L., Li, Z., Yu, S., Yang, H., Zhou, X., Zou, L., Zhang, X., Sun, Z., Li, J., & Sun, Y. (2013). Prehypertension is not associated with all-cause mortality: a systematic review and meta-analysis of prospective studies. PLoS One, 8(4), e61796. https://doi.org/10.1371/journal.pone.0061796
  • Huang, Y., Cai, X., Li, Y., Su, L., Mai, W., Wang, S., Hu, Y., Wu, Y., & Xu, D. (2014). Prehypertension and the risk of stroke: a meta-analysis. Neurology, 82(13), 1153-1161. https://doi.org/ 10.1161/JAHA.114.001519
  • Huang, Y., Cai, X., Liu, C., Zhu, D., Hua, J., Hu, Y., Peng, J., & Xu, D. (2015). Prehypertension and the risk of coronary heart disease in Asian and Western populations: a meta-analysis. Journal of the American Heart Association, 4(2), e001519. https://doi.org/ 10.1161/JAHA.114.001519
  • Huang, Y., Cai, X., Zhang, J., Mai, W., Wang, S., Hu, Y., Ren, H., & Xu, D. (2014). Prehypertension and incidence of ESRD: a systematic review and meta-analysis. American Journal of Kidney Diseases, 63(1), 76-83. https://doi.org/ 10.1053/j.ajkd.2013.07.024
  • Joham, A.E., Boyle, J.A., Zoungas, S., & Teede, H.J. (2015). Hypertension in reproductive-aged women with polycystic ovary syndrome and association with obesity. American Journal of Hypertension, 28(7), 847-851. https://doi.org/ 10.1093/ajh/hpu251
  • Keskin Kurt, R., Okyay, A.G., Hakverdi, A.U., Gungoren, A., Dolapcioglu, K.S., Karateke, A., & Dogan, M.O. (2014). The effect of obesity on inflammatory markers in patients with PCOS: a BMI-matched case-control study. Archives of Gynecology and Obstetrics, 290(2), 315-319. https://doi.org/ 10.1007/s00404-014-3199-3
  • Laffin, L.J., & Bakris, G.L. (2015). Hypertension and new treatment approaches targeting the sympathetic nervous system. Current Opinion in Pharmacology, 21, 20-24. https://doi.org/ 10.1016/j.coph.2014.12.006
  • Lewington, S., Clarke, R., Qizilbash, N., Peto, R., & Collins, R. (2002). Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet, 360, 1903-1913. https://doi.org/ 10.1016/s0140-6736(02)11911-8
  • Lo, J.C., Feigenbaum, S.L., Yang, J., Pressman, A.R., Selby, J.V., & Go, A.S. (2006). Epidemiology and adverse cardiovascular risk profile of diagnosed polycystic ovary syndrome. The Journal of Clinical Endocrinology & Metabolism, 91(4), 1357-1363. https://doi.org/ 10.1210/jc.2005-2430
  • Lord, J.M., Flight, I.H.K., & Norman, R.J. (2003). Metformin in polycystic ovary syndrome: systematic review and meta-analysis. BMJ, 327(7421), 951-953. https://doi.org/ 10.1136/bmj.327.7421.951
  • Meyer, C., McGrath, B.P., & Teede, H.J. (2005). Overweight women with polycystic ovary syndrome have evidence of subclinical cardiovascular disease. The Journal of Clinical Endocrinology & Metabolism, 90(10), 5711-5716. https://doi.org/ 10.1210/jc.2005-0011
  • Orbetzova, M.M., Shigarminova, R.G., Genchev, G.G., Milcheva, B.A., Lozanov, L.B., Genov, N.S., & Zacharieva, S.Z. (2003). Role of 24-hour monitoring in assessing blood pressure changes in polycystic ovary syndrome. Folia Medica, 45(3), 21-25.
  • Orio F Jr, Palomba S, Cascella T, De Simone B, Manguso F, Savastano S, Russo T, Tolino A, Zullo F, Lombardi G, Azziz R, Colao A. (2005). Improvement in endothelial structure and function after metformin treatment in young normal-weight women with polycystic ovary syndrome: results of a 6-month study. The Journal of Clinical Endocrinology & Metabolism, 90(11), 6072-3076. https://doi.org/10.1210/jc.2005-0965
  • Poulter, N.R., Prabhakaran, D., & Caulfield, M. (2015). Hypertension. Lancet, 386(9995), 801-812. https://doi.org/ 10.1016/S0140-6736(14)61468-9
  • Sirmans, S.M., & Pate, K.A. (2014). Epidemiology, diagnosis, and management of polycystic ovary syndrome. Clinical Epidemiology, 6, 1-13. https://doi.org/ 10.2147/CLEP.S37559
  • Stein, I.F., & Leventhal, M.L. (1935). Amenorrhea associated with bilateral polycystic ovaries. American Journal of Obstetrics & Gynecology, 29(2), 181-191. https://doi.org/ 10.1016/S0002-9378(15)30642-6
  • Talbott, E., Clerici, A., Berga, S.L., Kuller, L., Guzick, D., Detre, K., Daniels, T., & Engberg, R.A. (1998). Adverse lipid and coronary heart disease risk profiles in young women with polycystic ovary syndrome: results of a case-control study. Journal of Clinical Epidemiology, 51(5), 415-422. Doi: https://doi.org/ 10.1016/s0895-4356(98)00010-9
  • Vrbíková, J., Cífková, R., Jirkovská, A., Lánská, V., Platilová, H., Zamrazil, V., & Stárka, L. (2003). Cardiovascular risk factors in young Czech females with polycystic ovary syndrome. Human Reproduction, 18(5), 980-984. https://doi.org/10.1093/humrep/deg218
  • Whelton, P.K., Carey, R.M., Aronow, W.S., Casey, D.E., Collins, K.J., Dennison Himmelfarb, C., DePalma, S.M., Gidding, S., Jamerson, K.A., Jones, D.W., MacLaughlin E.J., Muntner P., et al. (2018). 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Journal of the American College of Cardiology, 71(19), e127-e248. https://doi.org/10.1016/j.jacc.2017.11.006
  • Wild, R.A., Carmina, E., Diamanti-Kandarakis, E., Dokras, A., Escobar-Morreale, H.F., Futterweit, W., Lobo, R., Norman, R.J., Talbott, E., & Dumesic, D.A. (2010). Assessment of cardiovascular risk and prevention of cardiovascular disease in women with the polycystic ovary syndrome: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome (AE-PCOS) Society. The Journal of Clinical Endocrinology & Metabolism, 95(5), 2038-2049. https://doi.org/ 10.1210/jc.2009-2724
  • Wild, S., Pierpoint, T., Jacobs, H., & McKeigue, P. (2000). Long-term consequences of polycystic ovary syndrome: results of a 31 year follow-up study. Human Fertility 3(2), 101-105. https://doi.org/ 10.1080/1464727002000198781
  • Willey JZ, Moon YP, Kahn E, Rodriguez CJ, Rundek T, Cheung K, Sacco RL, Elkind MSV. (2014). Population attributable risks of hypertension and diabetes for cardiovascular disease and stroke in the northern Manhattan study. Journal of the American Heart Association, 3(5), e001106. https://doi.org/ 10.1161/JAHA.114.001106
  • Zimmermann, S., Phillips, R.A., Dunaif, A., Finegood, D.T., Wilkenfeld, C., Ardeljan, M., Gorlin, R., Krakoff, L.R. (1992). Polycystic ovary syndrome: lack of hypertension despite profound insulin resistance. The Journal of Clinical Endocrinology & Metabolism, 75(2), 508-513. https://doi.org/10.1210/jcem.75.2.1639952

Düzeltme: The Incidance of High Blood Pressure in Women with PCOS and Its Correlation with Clinical and Biochemical Parameters

Yıl 2022, Cilt: 11 Sayı: 1, 136 - 142, 28.02.2022
Bu makalenin ilk hali 31 Ağustos 2021 tarihinde yayımlandı. https://dergipark.org.tr/tr/pub/balikesirsbd/issue/64743/962549

Düzeltme Notu

Öz

Aim: Although blood pressure abnormalities are frequently encountered in patients with polycystic ovary syndrome (PCOS), the relationship between hypertension and PCOS has not been fully elucidated. Our aim of this study is to investigate BP alteration in patients with PCOS according to the new classification proposed by ACC/AHA guideline. Material and Methods: In this study, we compared the BP measurements and baseline characteristics of 64 patients with PCOS and 61 patients without PCOS in the same age group. Results: Compared with the control group, PCOS patients had increased Ferriman Gallwey score (p<0.0001), mean diastolic blood pressure (p=0.0099), glucose levels (p=0.0049), leukocyte counts (p=0.0319), neutrophil counts (p=0.0364) and LH levels (p=0.0018). When the PCOS and Control patients were classified according to the ACC/AHA guideline, 59.4% of the PCOS patients had abnormal BP, while 47.5% of the patients in the control group had abnormal BP. There was a statistically significant differences between the groups (p=0.0343). The correlation analysis showed that there were positive correlation between DBP levels and BMI, serum glucose level, HOMA-IR, total cholesterol and LDL cholesterol in PCOS patients. In addition, there was a negative correlation between DKB and HDL cholesterol levels in PCOS patients. Conclusion: It has been determined that BP (especially DBP) levels tend to increase in PCOS patients in the reproductive period in relation to the presence of insulin resistance, hyperandrogenemia and dyslipidemia, but there is no difference in the incidence of hypertension between PCOS and control groups.

Kaynakça

  • Alexander, C.J., Tangchitnob, E.P., & Lepor, N.E. (2009). Polycystic ovary syndrome: a major unrecognized cardiovascular risk factor in women. Reviews in Obstetrics and Gynecology, 2(4), 232-239.
  • Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group. (2012). Consensus on women’s health aspects of polycystic ovary syndrome (PCOS). Human Reproduction, 27(1), 14-24. https://doi.org/ 10.1093/humrep/der396
  • Azziz, R., Woods, K.S., Reyna, R., Key, T.J., Knochenhauer, E.S., & Yildiz, B.O. (2004). The prevalence and features of the polycystic ovary syndrome in an unselected population. The Journal of Clinical Endocrinology & Metabolism, 89(6), 2745-2749. https://doi.org/10.1210/jc.2003-032046
  • Bentley-Lewis, R., Seely, E., & Dunaif, A. (2011). Ovarian hypertension: polycystic ovary syndrome. Endocrinology and Metabolism Clinics of North America, 40(2), 433-449. https://doi.org/10.1016/j.ecl.2011.01.009
  • Boomsma, C.M., Fauser, B.C., & Macklon, N.S. (2008). Pregnancy complications in women with polycystic ovary syndrome. Seminars in Reproductive Medicine, 26(1), 72-84. https://doi.org/10.1055/s-2007-992927
  • Burghen, G.A., Givens, J.R., & Kitabchi, A.E. (1980). Correlation of hyperandrogenism with hyperinsulinism in polycystic ovarian disease. The Journal of Clinical Endocrinology & Metabolism, 50(1), 113-116. https://doi.org/ 10.1210/jcem-50-1-113
  • Carmina, E. (2009). Cardiovascular risk and events in polycystic ovary syndrome. Climacteric, 12 (Suppl 1), 22-25. https://doi.org/ 10.1080/13697130903003842
  • Conway, G.S., Agrawal, R., Betteridge, D.J., & Jacobs, H.S. (1992). Risk factors for coronary artery disease in lean and obese women with the polycystic ovary syndrome. Clinical Endocrinology 37(2), 119-125. https://doi.org/ 10.1111/j.1365-2265.1992.tb02295.x Diamanti-Kandarakis, E., Alexandraki, K., Piperi, C., Aessopos, A., Paterakis T, Katsikis I., & Panidis, D. (2007). Effect of metformin administration on plasma advanced glycation end product levels in women with polycystic ovary syndrome. Metabolism, 56(1), 129-134. https://doi.org/ 10.1016/j.metabol.2006.09.006
  • Elting, M.W., Korsen, T.J., Bezemer, P.D., & Schoemaker J. (2001). Prevalence of diabetes mellitus, hypertension and cardiac complaints in a follow-up study of a Dutch PCOS population. Human Reproduction, 16(3), 556-560. https://doi.org/ 10.1093/humrep/16.3.556
  • Ferriman, D., & Gallwey, J.D. (1961). Clinical assessment of body hair growth in women. The Journal of Clinical Endocrinology & Metabolism, 21, 1440-1447. https://doi.org/ 10.1210/jcem-21-11-1440
  • Guo, X., Zhang, X., Guo, L., Li, Z., Zheng, L., Yu, S., Yang, H., Zhou, X., Zhang, X., Sun, Z., Li, J., Sun, Y. (2013). Association between pre-hypertension and cardiovascular outcomes: a systematic review and meta-analysis of prospective studies. Current Hypertension Reports, 15(6), 703-716. https://doi.org/ 10.1007/s11906-013-0403-y
  • Guo, X., Zhang, X., Zheng, L., Guo, L., Li, Z., Yu, S., Yang, H., Zhou, X., Zou, L., Zhang, X., Sun, Z., Li, J., & Sun, Y. (2013). Prehypertension is not associated with all-cause mortality: a systematic review and meta-analysis of prospective studies. PLoS One, 8(4), e61796. https://doi.org/10.1371/journal.pone.0061796
  • Huang, Y., Cai, X., Li, Y., Su, L., Mai, W., Wang, S., Hu, Y., Wu, Y., & Xu, D. (2014). Prehypertension and the risk of stroke: a meta-analysis. Neurology, 82(13), 1153-1161. https://doi.org/ 10.1161/JAHA.114.001519
  • Huang, Y., Cai, X., Liu, C., Zhu, D., Hua, J., Hu, Y., Peng, J., & Xu, D. (2015). Prehypertension and the risk of coronary heart disease in Asian and Western populations: a meta-analysis. Journal of the American Heart Association, 4(2), e001519. https://doi.org/ 10.1161/JAHA.114.001519
  • Huang, Y., Cai, X., Zhang, J., Mai, W., Wang, S., Hu, Y., Ren, H., & Xu, D. (2014). Prehypertension and incidence of ESRD: a systematic review and meta-analysis. American Journal of Kidney Diseases, 63(1), 76-83. https://doi.org/ 10.1053/j.ajkd.2013.07.024
  • Joham, A.E., Boyle, J.A., Zoungas, S., & Teede, H.J. (2015). Hypertension in reproductive-aged women with polycystic ovary syndrome and association with obesity. American Journal of Hypertension, 28(7), 847-851. https://doi.org/ 10.1093/ajh/hpu251
  • Keskin Kurt, R., Okyay, A.G., Hakverdi, A.U., Gungoren, A., Dolapcioglu, K.S., Karateke, A., & Dogan, M.O. (2014). The effect of obesity on inflammatory markers in patients with PCOS: a BMI-matched case-control study. Archives of Gynecology and Obstetrics, 290(2), 315-319. https://doi.org/ 10.1007/s00404-014-3199-3
  • Laffin, L.J., & Bakris, G.L. (2015). Hypertension and new treatment approaches targeting the sympathetic nervous system. Current Opinion in Pharmacology, 21, 20-24. https://doi.org/ 10.1016/j.coph.2014.12.006
  • Lewington, S., Clarke, R., Qizilbash, N., Peto, R., & Collins, R. (2002). Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet, 360, 1903-1913. https://doi.org/ 10.1016/s0140-6736(02)11911-8
  • Lo, J.C., Feigenbaum, S.L., Yang, J., Pressman, A.R., Selby, J.V., & Go, A.S. (2006). Epidemiology and adverse cardiovascular risk profile of diagnosed polycystic ovary syndrome. The Journal of Clinical Endocrinology & Metabolism, 91(4), 1357-1363. https://doi.org/ 10.1210/jc.2005-2430
  • Lord, J.M., Flight, I.H.K., & Norman, R.J. (2003). Metformin in polycystic ovary syndrome: systematic review and meta-analysis. BMJ, 327(7421), 951-953. https://doi.org/ 10.1136/bmj.327.7421.951
  • Meyer, C., McGrath, B.P., & Teede, H.J. (2005). Overweight women with polycystic ovary syndrome have evidence of subclinical cardiovascular disease. The Journal of Clinical Endocrinology & Metabolism, 90(10), 5711-5716. https://doi.org/ 10.1210/jc.2005-0011
  • Orbetzova, M.M., Shigarminova, R.G., Genchev, G.G., Milcheva, B.A., Lozanov, L.B., Genov, N.S., & Zacharieva, S.Z. (2003). Role of 24-hour monitoring in assessing blood pressure changes in polycystic ovary syndrome. Folia Medica, 45(3), 21-25.
  • Orio F Jr, Palomba S, Cascella T, De Simone B, Manguso F, Savastano S, Russo T, Tolino A, Zullo F, Lombardi G, Azziz R, Colao A. (2005). Improvement in endothelial structure and function after metformin treatment in young normal-weight women with polycystic ovary syndrome: results of a 6-month study. The Journal of Clinical Endocrinology & Metabolism, 90(11), 6072-3076. https://doi.org/10.1210/jc.2005-0965
  • Poulter, N.R., Prabhakaran, D., & Caulfield, M. (2015). Hypertension. Lancet, 386(9995), 801-812. https://doi.org/ 10.1016/S0140-6736(14)61468-9
  • Sirmans, S.M., & Pate, K.A. (2014). Epidemiology, diagnosis, and management of polycystic ovary syndrome. Clinical Epidemiology, 6, 1-13. https://doi.org/ 10.2147/CLEP.S37559
  • Stein, I.F., & Leventhal, M.L. (1935). Amenorrhea associated with bilateral polycystic ovaries. American Journal of Obstetrics & Gynecology, 29(2), 181-191. https://doi.org/ 10.1016/S0002-9378(15)30642-6
  • Talbott, E., Clerici, A., Berga, S.L., Kuller, L., Guzick, D., Detre, K., Daniels, T., & Engberg, R.A. (1998). Adverse lipid and coronary heart disease risk profiles in young women with polycystic ovary syndrome: results of a case-control study. Journal of Clinical Epidemiology, 51(5), 415-422. Doi: https://doi.org/ 10.1016/s0895-4356(98)00010-9
  • Vrbíková, J., Cífková, R., Jirkovská, A., Lánská, V., Platilová, H., Zamrazil, V., & Stárka, L. (2003). Cardiovascular risk factors in young Czech females with polycystic ovary syndrome. Human Reproduction, 18(5), 980-984. https://doi.org/10.1093/humrep/deg218
  • Whelton, P.K., Carey, R.M., Aronow, W.S., Casey, D.E., Collins, K.J., Dennison Himmelfarb, C., DePalma, S.M., Gidding, S., Jamerson, K.A., Jones, D.W., MacLaughlin E.J., Muntner P., et al. (2018). 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Journal of the American College of Cardiology, 71(19), e127-e248. https://doi.org/10.1016/j.jacc.2017.11.006
  • Wild, R.A., Carmina, E., Diamanti-Kandarakis, E., Dokras, A., Escobar-Morreale, H.F., Futterweit, W., Lobo, R., Norman, R.J., Talbott, E., & Dumesic, D.A. (2010). Assessment of cardiovascular risk and prevention of cardiovascular disease in women with the polycystic ovary syndrome: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome (AE-PCOS) Society. The Journal of Clinical Endocrinology & Metabolism, 95(5), 2038-2049. https://doi.org/ 10.1210/jc.2009-2724
  • Wild, S., Pierpoint, T., Jacobs, H., & McKeigue, P. (2000). Long-term consequences of polycystic ovary syndrome: results of a 31 year follow-up study. Human Fertility 3(2), 101-105. https://doi.org/ 10.1080/1464727002000198781
  • Willey JZ, Moon YP, Kahn E, Rodriguez CJ, Rundek T, Cheung K, Sacco RL, Elkind MSV. (2014). Population attributable risks of hypertension and diabetes for cardiovascular disease and stroke in the northern Manhattan study. Journal of the American Heart Association, 3(5), e001106. https://doi.org/ 10.1161/JAHA.114.001106
  • Zimmermann, S., Phillips, R.A., Dunaif, A., Finegood, D.T., Wilkenfeld, C., Ardeljan, M., Gorlin, R., Krakoff, L.R. (1992). Polycystic ovary syndrome: lack of hypertension despite profound insulin resistance. The Journal of Clinical Endocrinology & Metabolism, 75(2), 508-513. https://doi.org/10.1210/jcem.75.2.1639952
Toplam 34 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Sağlık Kurumları Yönetimi
Bölüm Makaleler
Yazarlar

Özgür Bulmuş 0000-0001-7736-402X

Akın Usta 0000-0001-8973-4374

Yayımlanma Tarihi 28 Şubat 2022
Gönderilme Tarihi 5 Temmuz 2021
Yayımlandığı Sayı Yıl 2022 Cilt: 11 Sayı: 1

Kaynak Göster

APA Bulmuş, Ö., & Usta, A. (2022). PKOS Hastalarında Yüksek Kan Basıncı Sıklığı ve Bunun Klinik ve Laboratuvar Parametrelerle İlişkisi. Balıkesir Sağlık Bilimleri Dergisi, 11(1), 136-142.

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