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Diabetic wound healing with medicinal plants: Past and present approaches

Cilt: 6 Sayı: 3 30 Aralık 2025
Pranjal Sachan *, Anjali Pandey
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Diabetic wound healing with medicinal plants: Past and present approaches

Öz

Diabetic wounds are characterized by their tendency to heal slowly, exhibit persistent inflammation, and become readily infected, which significantly complicates the overall wound-healing process. While conventional treatments often fall short in delivering lasting solutions, medicinal plants have emerged as a promising alternative for wound care. Rooted in ancient healing traditions, these herbal remedies are now gaining scientific recognition for their effectiveness in managing diabetic wounds. Compounds such as flavonoids, alkaloids, tannins, and terpenoids contribute to wound healing by exhibiting antimicrobial, anti-inflammatory, antioxidant, and angiogenic properties. These bioactive constituents accelerate tissue regeneration while minimizing complications, making them valuable in diabetic wound management. This review aims to connect traditional herbal wisdom with modern scientific insights by exploring key medicinal plants, their phytochemical mechanisms, and their therapeutic benefits in wound healing. With further clinical research and advancements in biotechnology, these natural remedies could become integral to mainstream diabetic wound care, providing safer, more affordable, and sustainable treatment options.

Anahtar Kelimeler

Diabetic wounds, herbal medicine, phytotherapy, tissue regeneration, angiogenesis, inflammation

Kaynakça

  1. Aboelsoud, N. H. (2010). Herbal medicine in ancient Egypt. Journal of Medicinal Plants Research, 4(2), 082–086.
  2. Akanda, M. K. M., Hasan, A. H. M. N., Mehjabin, S., Parvez, G. M. M., Yasmin, S., Akhtar, M. S., Anjum, S., Ashique, S., Sulatana, R., & Ansari, M. Y. (2025). Carica papaya in health and disease: a review of its bioactive compounds for treating various disease conditions, including anti-inflammatory and anti-arthritic activities. Inflammopharmacology, 33(6), 3051–3084. https://doi.org/10.1007/s10787-025-01780-4
  3. Arribas-López, E., Zand, N., Ojo, O., Snowden, M. J., & Kochhar, T. (2022). A systematic review of the effect of Centella asiatica on wound healing. International Journal of Environmental Research and Public Health, 19(6), 3266. https://doi.org/10.3390/ijerph19063266
  4. Bharathy, P., & Thanikachalam, P. V. (2024). Harnessing traditional herbal medicine: Molecular insights into diabetic wound healing for modern therapeutics. Digital Chinese Medicine, 7(4), 388–404. https://doi.org/10.1016/j.dcmed.2025.01.003
  5. Bhowmik, D., Gopinath, H., Kumar, B. P., Duraivel, S., Aravind, G., & Kumar, K. P. (2013). Medicinal uses of Punica granatum and its health benefits. Journal of Pharmacognosy and Phytochemistry, 1(5), 1-5.
  6. Budovsky, A., Yarmolinsky, L., & Ben-Shabat, S. (2015). Effect of medicinal plants on wound healing. Wound Repair and Regeneration, 23(2), 171–183. https://doi.org/10.1111/wrr.12274
  7. Chithra, P., Sajithlal, G. B., & Chandrakasan, G. (1998). Influence of aloe vera on the healing of dermal wounds in diabetic rats. Journal of ethnopharmacology, 59(3), 195–201.
  8. Diniz, L. R. L., Calado, L. L., Duarte, A. B. S., & de Sousa, D. P. (2023). Centella asiatica and Its Metabolite Asiatic Acid: Wound Healing Effects and Therapeutic Potential. Metabolites, 13(2), 276. https://doi.org/10.3390/metabo13020276
  9. Dwivedi, J., Kumar, P., Sachan, P., Singh, C., Saxena, B., Wal, A., & Wal, P. (2025). Phyto-pharmacological potential of Aegle marmelos (L.) for neurological disorders: Progress and prospects. Recent Patents on Food, Nutrition & Agriculture, 16(1), 12–30.
  10. Elanthamilan, E., & Wang, S. F. (2025). Honeycomb-like mesoporous activated carbon derived from Annona squamosa fruit seeds: As a high-performance electrode material for symmetric and asymmetric supercapacitors. Journal of Energy Storage, 132, 117738. https://doi.org/10.1016/j.est.2025.117738

Kaynak Göster

APA
Sachan, P., & Pandey, A. (2025). Diabetic wound healing with medicinal plants: Past and present approaches. Journal of Integrative and Anatolian Medicine, 6(3), 209-222. https://doi.org/10.53445/batd.1701433
AMA
1.Sachan P, Pandey A. Diabetic wound healing with medicinal plants: Past and present approaches. J. Integr. Anatol. Med. 2025;6(3):209-222. doi:10.53445/batd.1701433
Chicago
Sachan, Pranjal, ve Anjali Pandey. 2025. “Diabetic wound healing with medicinal plants: Past and present approaches”. Journal of Integrative and Anatolian Medicine 6 (3): 209-22. https://doi.org/10.53445/batd.1701433.
EndNote
Sachan P, Pandey A (01 Aralık 2025) Diabetic wound healing with medicinal plants: Past and present approaches. Journal of Integrative and Anatolian Medicine 6 3 209–222.
IEEE
[1]P. Sachan ve A. Pandey, “Diabetic wound healing with medicinal plants: Past and present approaches”, J. Integr. Anatol. Med., c. 6, sy 3, ss. 209–222, Ara. 2025, doi: 10.53445/batd.1701433.
ISNAD
Sachan, Pranjal - Pandey, Anjali. “Diabetic wound healing with medicinal plants: Past and present approaches”. Journal of Integrative and Anatolian Medicine 6/3 (01 Aralık 2025): 209-222. https://doi.org/10.53445/batd.1701433.
JAMA
1.Sachan P, Pandey A. Diabetic wound healing with medicinal plants: Past and present approaches. J. Integr. Anatol. Med. 2025;6:209–222.
MLA
Sachan, Pranjal, ve Anjali Pandey. “Diabetic wound healing with medicinal plants: Past and present approaches”. Journal of Integrative and Anatolian Medicine, c. 6, sy 3, Aralık 2025, ss. 209-22, doi:10.53445/batd.1701433.
Vancouver
1.Pranjal Sachan, Anjali Pandey. Diabetic wound healing with medicinal plants: Past and present approaches. J. Integr. Anatol. Med. 01 Aralık 2025;6(3):209-22. doi:10.53445/batd.1701433