KOLOREKTAL POLİPLERİN KLİNİKOPATOLOJİK ÖZELLİKLERİ: TÜRKİYE'NİN KUZEY-DOĞU ANADOLU BÖLGESİNDEN RETROSPEKTİF BİR ÇALIŞMA

Öz

Amaç: Bu çalışmanın amacı kolon poliplerinin lokalizasyon, prezentasyon ve histopatolojik özelliklerini incelemektir.

Gereç ve Yöntemler: 2014-2016 yılları arasında Ağrı Devlet Hastanesi ve Erzurum Bölge Eğitim ve Araştırma Hastanesi'nde kolon polibi nedeni ile kolonoskopi yapılan 123 hastanın 153 biyopsi örneğini retrospektif olarak inceledik.

Bulgular: Ortalama yaş 58.9 ± 15.6 yıldı (Dağılım: 19-90 yıl). Hastaların 78'i (% 63,4) erkek, 45'i (% 36,6) kadındı. 25 (% 20.3) hastada iki veya üç (çoklu) polip vardı. 4 biyopsi örneğinde (% 2.6) tübüler adenomadan karsinom tanısı kondu. En yaygın polip türü adenomatöz polip (n: 123,% 80.3) idi. Poliplerin en sık anatomik lokasyonları 45 (% 29.4) olguda rektum, 45 (% 29.4) olguda sigmoid kolon idi. Poliplerin ortalama büyüklüğü 4,1 mm (aralık: 1 mm-20 mm) idi. Yüksek dereceli displazi, 123 (% 13.2) adenomatöz polipten 20'sinde saptandı. Yüksek dereceli displazi ve düşük dereceli displazili adenomatöz poliplerde ortalama çaplar anlamlı olarak farklıydı (p <0.05).

Sonuç: Poliplerin çoğu 50 yaş ve üzerindeki hastalarda tanımlandı. Poliplerin % 50'sinden fazlası kolonun rektosigmoid bölümünde bulundu. Poliplerin çoğunluğu adenomatöz idi ve geniş çaplı poliplerde yüksek dereceli displazi saptandı.

Anahtar Kelimeler

• adenoma,displazi,adenomatöz polipler

CLINICOPATHOLOGIC FEATURES OF COLORECTAL POLYPS: A RETROSPECTIVE STUDY FROM NORTH-EASTERN ANATOLIA REGION OF TURKEY

Öz

Objectives: The aim of this study is to examine the patient characteristics, locations, presentations and histopathological features of colon polyps.

Material and methods: We analyzed 153 biopsy specimens of 123 patients who underwent colonoscopy with biopsy of colonic polyps during a two-year period from 2014 to 2016, in Ağrı State Hospital and Erzurum Regional Training and Research Hospital, retrospectively. 

Results: The mean age was 58.9±15.6 years (Range: 19-90 years).  78 (63.4%) patients were males and 45 (36.6%) patients were females. 25 (20.3%) patients had two or three (multiple) polyps. In 4 biopsy specimens (2.6%) were diagnosed with carcinoma arose from tubular adenomas. The most common type of polyp was the adenomatous polyp (n:123, 80.3%).  The most common anatomical locations of polyps were the rectum in 45 (29.4%) cases and the sigmoid colon in 45 (29.4%) cases. The mean size of polyps was 4.1 mm (range: 1mm-20 mm). High-grade dysplasia was found in 20 of 123 (13.2%) adenomatous polyps. Mean diameters were significantly different in adenomatous polyps with high-grade dysplasia and low-grade dysplasia (p<0.05).

Conclusion: Most of the polyps were identified in patients aged 50 years or older. More than 50% of the polyps were found in the rectosigmoid part of the colon. The majority of the polyps were adenomatous and high-grade dysplasia was detected in large diameter polyps. 

Anahtar Kelimeler

• dysplasia,adenoma,adenomatous polyps

Kaynakça

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