Importance of Routine Biopsy in Percutaneous Vertebroplasty Surgery Applied for the Treatment of Vertebral Compression Fractures
Öz
Aim: The purpose of this study was to emphasize the importance of conducting a biopsy during percutaneous vertebroplasty surgery for vertebral compression fractures.
Material and Method: 73 patients with vertebral compression fractures who did not have primary malignancy or metabolic disease were included in the study. All patients had percutaneous vertebroplasty and biopsies were obtained during the procedure. Fracture levels were recorded. The patients’ preoperative and postoperative pain levels were evaluated with VAS scores.
Results: Of the 73 patients we treated, 13 were male and 60 were female. The patients’ average age was 75.60 (range 51-91). Biopsies were obtained from 116 fractured vertebral levels of a total of 73 patients. The biopsy of 1 patient (0.86%) was observed to be compatible with multiple myeloma. The mean VAS score of the patients was 9.22 preoperatively and 1.34 in the postoperative 6th week. No statistically significant relationship between fracture level or patient age and pain was found (p>0.05).
Conclusions: In the study, it was seen that even if osteoporosis is very common in the etiology of patients operated on due to VCF, it is important to take biopsies from all levels. Although rare, unexpected malignancies can be considered a cause of VCFs.
Anahtar Kelimeler
Compression fracture, Vertebroplasty, Biopsy, Pain, Malignancy
Proje Numarası
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Kaynakça
- Anselmetti, G. C., Corrao, G., Monica, P. D., Tartaglia, V., Manca, A., Eminefendic, H., … Regge, D. (2007). Pain Relief Following Percutaneous Vertebroplasty: Results of a Series of 283 Consecutive Patients Treated in a Single Institution. CardioVascular and Interventional Radiology, 30(3), 441–447. doi:10.1007/s00270-006-0146-0
- Cooper, C., Atkinson, E. J., MichaelO’Fallon, W., & Melton, J. L. (2009). Incidence of clinically diagnosed vertebral fractures: A population-based study in rochester, minnesota, 1985-1989. Journal of Bone and Mineral Research, 7(2), 221–227. doi: 0.1002/jbmr.5650070214
- Donnally III, C. J., DiPompeo, C. M., & Varacallo, M. (2023). Vertebral Compression Fractures. Treasure Island (FL), StatPearls Publishing.
- Ensrud, K. E., & Schousboe, J. T. (2011). Vertebral Fractures. New England Journal of Medicine, 364(17), 1634–1642. doi: 10.1056/NEJMcp1009697
- Ettinger, B., Black, D. M., Nevitt, M. C., Rundle, A. C., Cauley, J. A., Cummings, S. R., & Genant, H. K. (1992). Contribution of vertebral deformities to chronic back pain and disability. Journal of Bone and Mineral Research, 7(4), 449–456. doi:10.1002/jbmr.5650070413
- Evans, A. J., Kip, K. E., & Boutin, S. M. (2009). Prospective assessment of pain and functional status after vertebroplasty for treatment of vertebral compression fractures. Journal of NeuroInterventional Surgery, 1(1), 66–70. doi:10.1136/jnis.2009.000158
- Francis, R. M., Baillie, S. P., Chuck, A. J., Crook, P. R., Dunn, N., Fordham, J. N., … Rodgers, A. (2004). Acute and long-term management of patients with vertebral fractures. QJM, 97(2), 63–74. doi:10.1093/qjmed/hch012
- Gangi, A., Guth, S., Imbert, J. P., Marin, H., & Dietemann, J.-L. (2003). Percutaneous Vertebroplasty: Indications, Technique, and Results. RadioGraphics, 23(2), e10–e10. doi:10.1148/rg.e10
- Garfin, S. R., Buckley, R. A., & Ledlie, J. (2006). Balloon Kyphoplasty for Symptomatic Vertebral Body Compression Fractures Results in Rapid, Significant, and Sustained Improvements in Back Pain, Function, and Quality of Life for Elderly Patients. Spine, 31(19), 2213–2220. doi:10.1097/01.brs.0000232803.71640.ba
- Ho, C.-S., Choi, W.-M., Chen, C., Chen, W.-Y., & Chan, W. P. (2005). Metastasis in vertebra mimicking acute compression fractures in a patient with osteoporosis. Clinical Imaging, 29(1), 64–67. doi:10.1016/j.clinimag.2004.04.025