TÜRKİYE’DE BULUNAN VİTİLOGOLU HASTALARIN İŞİTMELERİNİN DEĞERLENDİRİLMESİ An Evaluation of the Hearing Examinations of Vitiligo Patients in Turkey

Öz

Amaç: Vitiligo, depigmente makula ve belirgin melanosit yıkımıyla karekterize edinsel, idiopatik, otoimmün

bir hastalıktır. Çalışma vitilogo hastalarında olası odyolojik anormallikleri saptamak için planlandı. Konvansiyonel

odyolojik testlerle (saf ses eşiği ) ve transient otoakustik emisyon (TEOAE) ile vitiligo hastalarında koklear

fonksiyonları ölçtük ve kontrol grubuyla karşılaştırdık.

Materyal ve Metot: Vitiligolu 32 hasta cinsiyetçe benzer 32 sağlıklı kişi çalışmaya alındı. Odyometrik ve

TEOAE testleri hasta ve kontrol grubunda yapıldı. Odyometrik ölçümler ses geçirmeyen kabinde saf ses odyometriyle

yapıldı. Saf ses eşikleri 250-6000 Hz’de her kulak için ölçüldü.

Bulgular: Odyometrik bulgular vitiligolu hastalar ve kontrol grubu arasında 250-6000 Hz arası saf ses eşiklerinde

fark olmadığını ortaya koydu. Vitiligolu hastalarda saf ses odyogramda sensörinöral işitme kaybı yoktu.

Vitiligolu hastalarda saf ses odyometride değişiklik olmasa da transient otoakustik emisyon değerlerindeki düşmelerin

dış tüy hücrelerini etkilediği düşünülebilir.

Sonuç: Konvansiyonel odyometri ile birlikte TEOAE testleri koklear disfonsiyonun erken tanısında güvenilir

testlerdir. Vitiligolu hastalarda hastalığın ilerlemesi ve erken fark edilmesi açısından odyolojik incelemenin rutin

olarak yapılması gerektiğini düşünüyoruz.

ABSTRACT

Objective: Vitiligo is an acquired, idiopathic autoimmune disease characterized by depigmented maculae and

marked with melanocyte destruction. The study was performed to detect possible audiological abnormalities

in vitiligo patients. We aimed to use conventional audiological tests (pure tone threshold) and altered cochlear

function, by measuring and analyzing transient evoked otoacoustic emission (TEOAE) testing any subclinical

auditory abnormalities of in patients with vitiligo, compared with controls.

Materials and Methods: Thirty-three patients with vitiligo and 32 age- and sex-matched healthy control

cases were included in this study. Audiometric and TEOAE testings for both ears were performed for both

patients and controls. Audiometric examinations were performed using a pure tone audiometer in a silent

cabin. Pure tone thresholds were determined for each ear at frequencies of 250 – 6000 Hz for air conduction.

Results: Findings of the audiometric tests indicate that there was no difference between vitiligo and control

group cases in pure tone threshold values between 250 and 6000 Hz. There was not sensorineural hearing

loss on pure-tone audiogram in patients with vitiligo. Although there is no change in pure tone audiometry

in vitiligo patients, it is considered that reductions in transient evoked otoacoustic emission values began to

affect the outer hairy cells.

Conclusion: Conventional audiometry with TEOAE testing are reliable tests for the early detection of cochlear

dysfunction. All patients with vitiligo required routine monitoring and audiological assessments for early

identification and monitoring of changes as the disease progresses.

Anahtar Kelimeler

• Vitiligo; Odyometri; Transient uyarılmış otoakustik emisyon; Koklear disfonksiyon.

Kaynakça

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