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AKUT KORONER SENDROMLU HASTALARDA ÇOK DAMAR HASTALIĞI İLE KARDİYOVASKÜLER RİSK FAKTÖRLERİ ARASINDAKİ İLİŞKİ The Association Between Multivessel Disease and Cardiovascular Risk Factors in Patients with Acute Coronary Syndrome

Cilt: 9 Sayı: 4 27 Aralık 2019
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AKUT KORONER SENDROMLU HASTALARDA ÇOK DAMAR HASTALIĞI İLE KARDİYOVASKÜLER RİSK FAKTÖRLERİ ARASINDAKİ İLİŞKİ The Association Between Multivessel Disease and Cardiovascular Risk Factors in Patients with Acute Coronary Syndrome

Öz

ÖZET Amaç: Akut koroner sendrom olgularında ciddi darlık olan koroner arter sayısı ile kardiyovasküler risk faktörleri arasındaki ilişki değerlendirildi. Yöntemler: Bu çalışma retrospektif olarak dizayn edildi. 2016–2018 tarihleri arasında akut koroner sendrom sebebiyle koroner anjiografi yapılan 904 hasta çalışmaya dahil edildi. Ciddi koroner arter darlığı olmayan ve koroner operasyon geçiren hastalar çalışma dışı bırakıldı. Hastalar kritik koroner arter darlıklarına göre tek damar hastalığı (TDH) ve çok damar hastalığı (ÇDH) olacak şekilde iki gruba ayrıldı. ÇDH ile TDH olanlar klasik kardiyovasküler risk faktörleri açısından karşılaştırıldı. Bulgular: Hastaların 544’ünde (%60) ÇDH 365’inde (%40) TDH saptandı. ÇDH olan grupta yaş, hipertansiyon ve diyabet mellitus istatistiksel olarak daha fazla saptandı (sırasıyla p<0.001, p=0.003, p=0.005). TDH olan grupta ise erkek cinsiyet, aile öyküsü ve sigara içiciliği istatistiksel olarak daha fazla saptandı (sırasıyla p=0.006, p<0.001, p<0.001). Sonuç: Diyabet ve hipertansiyon ÇDH grubunda yüksek saptanırken aile öyküsü ve sigara içiciliği TDH grubunda yüksek saptandı. Akut koroner sendrom hastalarında bu risk faktörlerin göz önünde bulundurulması önemlidir. Anahtar Kelimeler: Koroner arter hastalığı; Kardiyovasküler risk faktörleri; Koroner anjiografi ABSTRACT Aim: The relationship between the number of coronary arteries with severe stenosis and cardiovascular risk factors was evaluated in patients with acute coronary syndrome. Material-Method: This study was designed retrospectively. 904 patients who underwent coronary angiography for acute coronary syndrome between 2016–2018 were included in the study. Patients who underwent coronary bypass surgery and didn’t have severe coronary artery disease were excluded. The patients were divided into two groups according to critical coronary artery stenosis as single vessel disease and multiple vessel disease. The relationship between multivessel disease and risk factors was compared. Results: Multivessel disease was detected in 544 (60%) patients and single vessel disease in 365 (40%) patients. Age, hypertension and diabetes were found to be higher in multivessel disease (respectively p<0.001, p=0.003, p=0.005). Male gender, family history and smoking were found to be higher in the single vessel disease. Conclusion: Diabetes and hypertension were higher in multivessel disease group, while family history and smoking were higher in single vessel disease group. It is important to consider these risk factors in patients with acute coronary syndrome. Key Words: Coronary artery disease; Cardiovascular risk factors; Coronary angiography

Anahtar Kelimeler

Kaynakça

  1. 1. Onat A, Kaya A, Akbaş Şimşek T, Şimşek B, Tusun E, Karadeniz Y, et al. Twenty-five years of the TARF study: The 2015 survey, and temporal trends in mortality and loss to follow-up. Turk Kardiyol Dern Ars. 2016; 44(5):365-70. 2. Alpert JS, Thygesen K, Antman E, Bassand JP. Myocardial infarction redefined--a consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction. J Am Coll Cardiol. 2000; 36(3):959-69. 3. Demir V, Yılmaz S, Ede H, Turan Y. Correlation of Resting Heart Rate with the Severity and Complexity of Coronary Artery Disease: A Single-Center Retrospective Study. Int J Prev Med. 2019; 7;10:104.4. Park DW, Clare RM, Schulte PJ, Pieper KS, Shaw LK, Califf RM, et al. Extent, location, and clinical significance of non-infarct-related coronary artery disease among patients with ST-elevation myocardial infarction. JAMA. 2014; 19;312(19):2019-27. 5. Fox K, GarciaMA, Ardissino D, Buszman P, Camici PG, Crea F, et al. Guidelines on the management of stable angina pectoris: executive summary: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology. Eur Heart J. 2006; 27:1341–81. 6. TEMD Obezite, Lipid Metabolizması, Hipertansiyon Çalışma Grubu. Obezite tanı ve tedavi kılavuzu, Türkiye Endokrinoloji ve Metabolizma Derneği 2017; 11-19. [İnternet: Türkiye Endokrinoloji ve Metabolizma Derneği]. Erişim: http://www.temd.org.tr/files/file/OBEZITE_TTK_web.pdf. 7. Demir V, Samet Y, Akboga MK. Association of lymphocyte-monocyte ratio and monocyte-to-high-density lipoprotein ratio with the presence and severity of rheumatic mitral valve stenosis. Biomark Med. 2017; 11(8):657-63. 8. Alp Ç, Dogru MT, Karadeniz M, Sarak T, Demir V, Çelik Y, et al. Serum pentraxin-3 levels and flow-mediated dilation in dipper and non-dipper hypertension. J Clin Lab Anal. 2019; 33(3):e22718. 9. Kumar A, Cannon CP. Acute coronary syndromes: diagnosis and management. Part I. Mayo Clin Proc. 2009; 84:917–38. 10. Ahmed MH, Awadalla H, Elmadhoun WM, Osman M, Noor SK, Almobarak AO. Prevalence and risk factors for acute coronary syndrome among sudanese individuals with diabetes: a population-based study. Cardiol Res. 2017; 8:184–9. 11. Larifla L, Armand C, Velayoudom-Cephise FL, Weladji G, Michel CT, Blanchet-Deverly A, et al. Distribution of coronary artery disease severity and risk factors in Afro-Caribbeans. Arch Cardiovasc Dis. 2014; 107(4):212-8. 12. Delp MD, Behnke BJ, Spier SA, Wu G, Muller-Delp JM. Ageing diminishes endothelium-dependent vasodilatation and tetrahydrobiopterin content in rat skeletal muscle arterioles. J Physiol. 2008; 15;586(4):1161-8. 13. Veeranna V, Pradhan J, Niraj A, Fakhry H, Afonso L. Traditional cardiovascular risk factors and severity of angiographic coronary artery disease in the elderly. Prev Cardiol. 2010;13(3):135-40. 14. Frei B, Forte TM, Ames BN, Cross CE. Gas phase oxidants of cigarette smoke induce lipid peroxidation and changes in lipoprotein properties in human blood plasma. Protective effects of ascorbic acid. Biochem J. 1991; 1;277 ( Pt 1):133-8. 15. Rival J, Riddle JM, Stein PD. Effects of chronic smoking on platelet function. Thromb Res. 1987; 45:75. 16. Haffner SM, Lehto S, Rönnemaa T, Pyörälä K, Laakso M. Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. N Engl J Med. 1998; 23;339(4):229-34. 17. Fuster V, Alexander RW O’Rourke R: Hurst’s The Heart. 10. Baskısının Türkçe çevirisi. And Danışmanlık Eğitim Yayıncılık ve Organizasyon Ltd. Şti.1. Basım. 2002; p. 1065-109.

Ayrıntılar

Birincil Dil

Türkçe

Konular

Sağlık Kurumları Yönetimi

Bölüm

Olgu Sunumu

Yazarlar

Muhammed Karadeniz Bu kişi benim
Türkiye

Taner Sarak Bu kişi benim
Türkiye

Vahit Demir Bu kişi benim
Türkiye

Yayımlanma Tarihi

27 Aralık 2019

Gönderilme Tarihi

1 Aralık 2019

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 2019 Cilt: 9 Sayı: 4

DOI

https://doi.org/10.16919/bozoktip.600489

IZ

https://izlik.org/JA42WC44RM

Kaynak Göster

RIS / Bibtex
APA
Alp, Ç., Karadeniz, M., Sarak, T., & Demir, V. (2019). AKUT KORONER SENDROMLU HASTALARDA ÇOK DAMAR HASTALIĞI İLE KARDİYOVASKÜLER RİSK FAKTÖRLERİ ARASINDAKİ İLİŞKİ The Association Between Multivessel Disease and Cardiovascular Risk Factors in Patients with Acute Coronary Syndrome. Bozok Tıp Dergisi, 9(4), 131-135. https://doi.org/10.16919/bozoktip.600489
AMA
1.Alp Ç, Karadeniz M, Sarak T, Demir V. AKUT KORONER SENDROMLU HASTALARDA ÇOK DAMAR HASTALIĞI İLE KARDİYOVASKÜLER RİSK FAKTÖRLERİ ARASINDAKİ İLİŞKİ The Association Between Multivessel Disease and Cardiovascular Risk Factors in Patients with Acute Coronary Syndrome. Bozok Tıp Dergisi. 2019;9(4):131-135. doi:10.16919/bozoktip.600489
Chicago
Alp, Çağlar, Muhammed Karadeniz, Taner Sarak, ve Vahit Demir. 2019. “AKUT KORONER SENDROMLU HASTALARDA ÇOK DAMAR HASTALIĞI İLE KARDİYOVASKÜLER RİSK FAKTÖRLERİ ARASINDAKİ İLİŞKİ The Association Between Multivessel Disease and Cardiovascular Risk Factors in Patients with Acute Coronary Syndrome”. Bozok Tıp Dergisi 9 (4): 131-35. https://doi.org/10.16919/bozoktip.600489.
EndNote
Alp Ç, Karadeniz M, Sarak T, Demir V (01 Aralık 2019) AKUT KORONER SENDROMLU HASTALARDA ÇOK DAMAR HASTALIĞI İLE KARDİYOVASKÜLER RİSK FAKTÖRLERİ ARASINDAKİ İLİŞKİ The Association Between Multivessel Disease and Cardiovascular Risk Factors in Patients with Acute Coronary Syndrome. Bozok Tıp Dergisi 9 4 131–135.
IEEE
[1]Ç. Alp, M. Karadeniz, T. Sarak, ve V. Demir, “AKUT KORONER SENDROMLU HASTALARDA ÇOK DAMAR HASTALIĞI İLE KARDİYOVASKÜLER RİSK FAKTÖRLERİ ARASINDAKİ İLİŞKİ The Association Between Multivessel Disease and Cardiovascular Risk Factors in Patients with Acute Coronary Syndrome”, Bozok Tıp Dergisi, c. 9, sy 4, ss. 131–135, Ara. 2019, doi: 10.16919/bozoktip.600489.
ISNAD
Alp, Çağlar - Karadeniz, Muhammed - Sarak, Taner - Demir, Vahit. “AKUT KORONER SENDROMLU HASTALARDA ÇOK DAMAR HASTALIĞI İLE KARDİYOVASKÜLER RİSK FAKTÖRLERİ ARASINDAKİ İLİŞKİ The Association Between Multivessel Disease and Cardiovascular Risk Factors in Patients with Acute Coronary Syndrome”. Bozok Tıp Dergisi 9/4 (01 Aralık 2019): 131-135. https://doi.org/10.16919/bozoktip.600489.
JAMA
1.Alp Ç, Karadeniz M, Sarak T, Demir V. AKUT KORONER SENDROMLU HASTALARDA ÇOK DAMAR HASTALIĞI İLE KARDİYOVASKÜLER RİSK FAKTÖRLERİ ARASINDAKİ İLİŞKİ The Association Between Multivessel Disease and Cardiovascular Risk Factors in Patients with Acute Coronary Syndrome. Bozok Tıp Dergisi. 2019;9:131–135.
MLA
Alp, Çağlar, vd. “AKUT KORONER SENDROMLU HASTALARDA ÇOK DAMAR HASTALIĞI İLE KARDİYOVASKÜLER RİSK FAKTÖRLERİ ARASINDAKİ İLİŞKİ The Association Between Multivessel Disease and Cardiovascular Risk Factors in Patients with Acute Coronary Syndrome”. Bozok Tıp Dergisi, c. 9, sy 4, Aralık 2019, ss. 131-5, doi:10.16919/bozoktip.600489.
Vancouver
1.Çağlar Alp, Muhammed Karadeniz, Taner Sarak, Vahit Demir. AKUT KORONER SENDROMLU HASTALARDA ÇOK DAMAR HASTALIĞI İLE KARDİYOVASKÜLER RİSK FAKTÖRLERİ ARASINDAKİ İLİŞKİ The Association Between Multivessel Disease and Cardiovascular Risk Factors in Patients with Acute Coronary Syndrome. Bozok Tıp Dergisi. 01 Aralık 2019;9(4):131-5. doi:10.16919/bozoktip.600489